메뉴 건너뛰기




Volumn 70, Issue 4, 1998, Pages 442-454

Proteolytic cleavage and activation of PAK2 during UV irradiation- induced apoptosis in A431 cells

Author keywords

A431 cells; Apoptosis; CPP32 caspase 3; PAK2; UV irradiation

Indexed keywords

APOPTOSIS; ARTICLE; DNA CLEAVAGE; ENZYME ACTIVATION; ENZYME INHIBITION; IMMUNOBLOTTING; PRIORITY JOURNAL; PROTEIN DEGRADATION; ULTRAVIOLET IRRADIATION;

EID: 0032531273     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19980915)70:4<442::AID-JCB2>3.0.CO;2-J     Document Type: Article
Times cited : (42)

References (52)
  • 2
    • 0029134875 scopus 로고
    • Activation of an S6/H4 kinase (PAK65) from human placenta by intramolecular and intermolecular autophosphorylation
    • Benner GE, Dennis PB, Masaracchia RA (1995): Activation of an S6/H4 kinase (PAK65) from human placenta by intramolecular and intermolecular autophosphorylation. J Biol Chem 270: 21121-21128.
    • (1995) J Biol Chem , vol.270 , pp. 21121-21128
    • Benner, G.E.1    Dennis, P.B.2    Masaracchia, R.A.3
  • 3
    • 0031026569 scopus 로고    scopus 로고
    • p21-activated kinase has substrate specificity similar to Acanthamoeba myosin I heavy chain kinase and activates Acanthamoeba myosin I
    • Brzeska H, Knaus UG, Wang Z-Y, Bokoch GM, Korn ED (1997): p21-activated kinase has substrate specificity similar to Acanthamoeba myosin I heavy chain kinase and activates Acanthamoeba myosin I. Proc Natl Acad Sci USA 94: 1092-1095.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 1092-1095
    • Brzeska, H.1    Knaus, U.G.2    Wang, Z.-Y.3    Bokoch, G.M.4    Korn, E.D.5
  • 4
    • 0028176651 scopus 로고
    • Oxidative stress as a mediator of apoptosis
    • Buttke TM, Sandstrom (1994): Oxidative stress as a mediator of apoptosis. Immunol. Today 15: 7-10.
    • (1994) Immunol. Today , vol.15 , pp. 7-10
    • Buttke, T.M.1    Sandstrom2
  • 6
    • 0028329953 scopus 로고
    • JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
    • Derijard B, Hibi M, Wu IH, Barrett T, Su B, Deng T, Karin M, Davis RJ (1994): JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76: 1025-1037.
    • (1994) Cell , vol.76 , pp. 1025-1037
    • Derijard, B.1    Hibi, M.2    Wu, I.H.3    Barrett, T.4    Su, B.5    Deng, T.6    Karin, M.7    Davis, R.J.8
  • 7
    • 0030806351 scopus 로고    scopus 로고
    • Comparison of apoptosis in wild-type and Fas-resistant cells: Chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions
    • Eischen CM, Kottke TJ, Martins LM, Basi GS, Tung JS, Earnshaw WC, Leibson PJ, Kaufmann SH (1997): Comparison of apoptosis in wild-type and Fas-resistant cells: chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions. Blood 90: 935-943.
    • (1997) Blood , vol.90 , pp. 935-943
    • Eischen, C.M.1    Kottke, T.J.2    Martins, L.M.3    Basi, G.S.4    Tung, J.S.5    Earnshaw, W.C.6    Leibson, P.J.7    Kaufmann, S.H.8
  • 10
    • 0027973061 scopus 로고
    • CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 β-converting enzyme
    • Fernandes-Alnemri T, Litwack G, Alnemri ES (1994): CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 β-converting enzyme. J Biol Chem 269: 30761-30764.
    • (1994) J Biol Chem , vol.269 , pp. 30761-30764
    • Fernandes-Alnemri, T.1    Litwack, G.2    Alnemri, E.S.3
  • 11
    • 0026456536 scopus 로고
    • DNA damage-induced gene expression: Signal transduction and relation to growth factor signalling
    • Herrlich P, Ponta H, Rahmsdorf HJ (1992): DNA damage-induced gene expression: signal transduction and relation to growth factor signalling. Rev Physiol Biochem Pharmacol 119: 187-223.
    • (1992) Rev Physiol Biochem Pharmacol , vol.119 , pp. 187-223
    • Herrlich, P.1    Ponta, H.2    Rahmsdorf, H.J.3
  • 12
    • 0029915841 scopus 로고    scopus 로고
    • Molecular cloning and sequencing of the cytostatic G protein-activated protein kinase PAK I
    • Jakobi R, Chen C-J, Tuazon PT, Traugh JA (1996): Molecular cloning and sequencing of the cytostatic G protein-activated protein kinase PAK I. J Biol Chem 271: 6206-6211.
    • (1996) J Biol Chem , vol.271 , pp. 6206-6211
    • Jakobi, R.1    Chen, C.-J.2    Tuazon, P.T.3    Traugh, J.A.4
  • 13
    • 0024358172 scopus 로고
    • A sensitive method for detection of calmodulin-dependent protein kinase II activity in sodium dodecyl sulfate-polyacrylamide gel
    • Kameshita I, Fujisawa H (1989): A sensitive method for detection of calmodulin-dependent protein kinase II activity in sodium dodecyl sulfate-polyacrylamide gel. Anal Biochem 183: 139-143.
    • (1989) Anal Biochem , vol.183 , pp. 139-143
    • Kameshita, I.1    Fujisawa, H.2
  • 14
    • 0015383455 scopus 로고
    • Apoptosis: A basis biological phenomenon with wide-ranging implication in tissue kinetics
    • Kerr J, Wyllie A, Currie A (1972): Apoptosis: A basis biological phenomenon with wide-ranging implication in tissue kinetics. Br J Cancer 26: 239-257.
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.1    Wyllie, A.2    Currie, A.3
  • 16
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during assembly of the head of bacteriophage T4
    • Laemmli UK (1970): Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature 227: 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 18
    • 0028290902 scopus 로고
    • The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis
    • Lee S, Esteban M (1994): The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis. Virology 199: 491-496.
    • (1994) Virology , vol.199 , pp. 491-496
    • Lee, S.1    Esteban, M.2
  • 19
    • 0029812075 scopus 로고    scopus 로고
    • UV irradiation-induced apoptosis leads to activation of a 36-kDa myelin basic protein kinase in HL-60 cells
    • Lu ML, Sato M, Cao B, Richie JP (1996): UV irradiation-induced apoptosis leads to activation of a 36-kDa myelin basic protein kinase in HL-60 cells. Proc Natl Acad Sci USA 93: 8977-8982.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 8977-8982
    • Lu, M.L.1    Sato, M.2    Cao, B.3    Richie, J.P.4
  • 20
    • 0028078824 scopus 로고
    • A brain serine/threonine protein kinase activated by Cdc 42 and Rac 1
    • Manser E, Leung T, Salihuddin H, Zhao Z-s, Lim L (1994): A brain serine/threonine protein kinase activated by Cdc 42 and Rac 1. Nature 367: 40-46.
    • (1994) Nature , vol.367 , pp. 40-46
    • Manser, E.1    Leung, T.2    Salihuddin, H.3    Zhao, Z.-S.4    Lim, L.5
  • 21
    • 0031036626 scopus 로고    scopus 로고
    • Expression of constitutively active α-PAK reveals effects of the kinase on actin and focal complexes
    • Manser E, Huang H-Y, Loo T-H, Chen X-Q, Dong J-M, Leung T, Lim L (1997): Expression of constitutively active α-PAK reveals effects of the kinase on actin and focal complexes. Mol Cell Biol 17: 1129-1143.
    • (1997) Mol Cell Biol , vol.17 , pp. 1129-1143
    • Manser, E.1    Huang, H.-Y.2    Loo, T.-H.3    Chen, X.-Q.4    Dong, J.-M.5    Leung, T.6    Lim, L.7
  • 22
    • 0029056399 scopus 로고
    • A novel serine kinase activated by racl/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20
    • Martin GA, Bollag G, McCormick F, Abo A. (1995): A novel serine kinase activated by racl/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20. EMBO J 14: 1970-1978.
    • (1995) EMBO J , vol.14 , pp. 1970-1978
    • Martin, G.A.1    Bollag, G.2    McCormick, F.3    Abo, A.4
  • 24
    • 0031106612 scopus 로고    scopus 로고
    • Apoptosis: Alive and kicking in 1997
    • Martins LM, Earnshaw WC (1997): Apoptosis: alive and kicking in 1997. Trends Cell Biol 7: 111-114.
    • (1997) Trends Cell Biol , vol.7 , pp. 111-114
    • Martins, L.M.1    Earnshaw, W.C.2
  • 28
    • 0029891838 scopus 로고    scopus 로고
    • The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A
    • Orth K, Chinnaiyan AM, Garg M, Froelich CJ, Dixit VM (1996): The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A. J Biol Chem 271: 16443-16446.
    • (1996) J Biol Chem , vol.271 , pp. 16443-16446
    • Orth, K.1    Chinnaiyan, A.M.2    Garg, M.3    Froelich, C.J.4    Dixit, V.M.5
  • 29
    • 0018902461 scopus 로고
    • Use of glutaraldehyde as a coupling agent for proteins and peptides
    • Reichlin M (1980): Use of glutaraldehyde as a coupling agent for proteins and peptides. Methods Enzymol 70: 159-165.
    • (1980) Methods Enzymol , vol.70 , pp. 159-165
    • Reichlin, M.1
  • 30
    • 0030918572 scopus 로고    scopus 로고
    • Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2
    • Rudel T, Bokoch GM (1997): Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2. Science 276: 1571-1574.
    • (1997) Science , vol.276 , pp. 1571-1574
    • Rudel, T.1    Bokoch, G.M.2
  • 31
    • 0027196547 scopus 로고
    • Control of programmed cell death in normal and leukemic cells: New implications for therapy
    • Sachs L, Loterm J (1993): Control of programmed cell death in normal and leukemic cells: New implications for therapy. Blood 82: 15-21.
    • (1993) Blood , vol.82 , pp. 15-21
    • Sachs, L.1    Loterm, J.2
  • 32
    • 0031127255 scopus 로고    scopus 로고
    • Emerging from the Pak: The p21-activated protein kinase family
    • Sells MA, Chernoff J (1997): Emerging from the Pak: the p21-activated protein kinase family. Trends Cell Biol 7: 162-167.
    • (1997) Trends Cell Biol , vol.7 , pp. 162-167
    • Sells, M.A.1    Chernoff, J.2
  • 35
    • 0028291525 scopus 로고
    • JNK is involved in signal integration during costimulation of T lymphocytes
    • Su B, Jacinto E, Hibi M, Kallunki T, Karin M, Ben-Neriah Y (1994): JNK is involved in signal integration during costimulation of T lymphocytes. Cell 77: 727-736.
    • (1994) Cell , vol.77 , pp. 727-736
    • Su, B.1    Jacinto, E.2    Hibi, M.3    Kallunki, T.4    Karin, M.5    Ben-Neriah, Y.6
  • 36
    • 0028842508 scopus 로고
    • Identification and molecular cloning of a p21cdc42/rac1-activated serine/threonine kinase that is rapidly activated by thrombin in platelets
    • Teo M, Manser E, Lim L (1995): Identification and molecular cloning of a p21cdc42/rac1-activated serine/threonine kinase that is rapidly activated by thrombin in platelets. J Biol Chem 270: 26690-26697.
    • (1995) J Biol Chem , vol.270 , pp. 26690-26697
    • Teo, M.1    Manser, E.2    Lim, L.3
  • 37
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson CB (1995): Apoptosis in the pathogenesis and treatment of disease. Science 267: 1456-1462.
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 40
    • 0027153429 scopus 로고
    • Microinjected catalytic subunit of cAMP-dependent protein kinase induced apoptosis in myeloid leukemia (IPC-81) cells
    • Vintermyr I, Gjertsen B, Lanotte M, Soskeland S (1993): Microinjected catalytic subunit of cAMP-dependent protein kinase induced apoptosis in myeloid leukemia (IPC-81) cells. Exp Cell Res 206:157-161.
    • (1993) Exp Cell Res , vol.206 , pp. 157-161
    • Vintermyr, I.1    Gjertsen, B.2    Lanotte, M.3    Soskeland, S.4
  • 41
    • 0028168593 scopus 로고
    • Ich-1, and Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death
    • Wang L, Miura M, Bergeron L, Zhu H, Yuan J (1994): Ich-1, and Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death. Cell 78: 739-750.
    • (1994) Cell , vol.78 , pp. 739-750
    • Wang, L.1    Miura, M.2    Bergeron, L.3    Zhu, H.4    Yuan, J.5
  • 43
    • 0018830636 scopus 로고
    • Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
    • Wyllie AH (1980) Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284: 555-556.
    • (1980) Nature , vol.284 , pp. 555-556
    • Wyllie, A.H.1
  • 44
  • 45
    • 0023664496 scopus 로고
    • Identification and characterization of a phosphorylation-activated, cAMP and Ca2+-independent protein kinase in brain
    • Yang S-D, Fong Y-L, Yu J-S, Liu J-S (1987a): Identification and characterization of a phosphorylation-activated, cAMP and Ca2+-independent protein kinase in brain. J Biol Chem 262: 7034-7040.
    • (1987) J Biol Chem , vol.262 , pp. 7034-7040
    • Yang, S.-D.1    Fong, Y.-L.2    Yu, J.-S.3    Liu, J.-S.4
  • 46
    • 0023645158 scopus 로고
    • Characterization of an autophosphory-lation-dependent multifunctional protein kinase from liver
    • Yang S-D, Chang S-Y, Soderling TR (1987b): Characterization of an autophosphory-lation-dependent multifunctional protein kinase from liver. J Biol Chem 262: 9421-9427.
    • (1987) J Biol Chem , vol.262 , pp. 9421-9427
    • Yang, S.-D.1    Chang, S.-Y.2    Soderling, T.R.3
  • 47
    • 0028176874 scopus 로고
    • Protein kinase FA/glycogen synthase kinase-3 predominantly phosphorylates the in vivo site Thr97-Pro in brain myelin basic protein. Evidence for Thr-Pro and Ser-Arg-X-X-Ser as consensus sequences motif
    • Yu J-S, Yang S-D (1994a): Protein kinase FA/glycogen synthase kinase-3 predominantly phosphorylates the in vivo site Thr97-Pro in brain myelin basic protein. Evidence for Thr-Pro and Ser-Arg-X-X-Ser as consensus sequences motif. J Neurochem 62:1596-1603.
    • (1994) J Neurochem , vol.62 , pp. 1596-1603
    • Yu, J.-S.1    Yang, S.-D.2
  • 48
    • 0028302780 scopus 로고
    • Okadaic acid, a serine/threonine phosphatase inhibitor, induces tyrosine dephosphorylation/inactivation of kinase FA/GSK-3α in A431 cells
    • Yu J-S, Yang S-D (1994b): Okadaic acid, a serine/threonine phosphatase inhibitor, induces tyrosine dephosphorylation/inactivation of kinase FA/GSK-3α in A431 cells. J Biol Chem 269:14341-14344.
    • (1994) J Biol Chem , vol.269 , pp. 14341-14344
    • Yu, J.-S.1    Yang, S.-D.2
  • 49
    • 0028017996 scopus 로고
    • Tyrosine dephosphorylation and concurrent inactivation of protein kinase FA/GSK-3α by genistein in A431 cells
    • Yu J-S, Yang S-D (1994c): Tyrosine dephosphorylation and concurrent inactivation of protein kinase FA/GSK-3α by genistein in A431 cells. J Cell Biochem 56:131-141.
    • (1994) J Cell Biochem , vol.56 , pp. 131-141
    • Yu, J.-S.1    Yang, S.-D.2
  • 50
    • 0028942047 scopus 로고
    • Phosphorylation/activation of phosphorylase b kinase by cAMP/Ca2+-independent, autophosphorylation-dependent protein kinase
    • Yu J-S, Yang S-D (1995): Phosphorylation/activation of phosphorylase b kinase by cAMP/Ca2+-independent, autophosphorylation-dependent protein kinase. Biochem Biophys Res Commun 207: 140-147.
    • (1995) Biochem Biophys Res Commun , vol.207 , pp. 140-147
    • Yu, J.-S.1    Yang, S.-D.2
  • 51
    • 0027525104 scopus 로고
    • The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 β-converting enzyme
    • Yuan J-Y, Shaham S, Ledoux S, Ellis HM, Horvitz HR (1993): The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 β-converting enzyme. Cell 75: 641-652.
    • (1993) Cell , vol.75 , pp. 641-652
    • Yuan, J.-Y.1    Shaham, S.2    Ledoux, S.3    Ellis, H.M.4    Horvitz, H.R.5
  • 52
    • 0031106826 scopus 로고    scopus 로고
    • An assay for DNA fragmentation in apotosis without phenol/chloroform extraction and ethanol precipitation
    • Zhu N, Wang Z (1997): An assay for DNA fragmentation in apotosis without phenol/chloroform extraction and ethanol precipitation. Anal Biochem 246: 155-158.
    • (1997) Anal Biochem , vol.246 , pp. 155-158
    • Zhu, N.1    Wang, Z.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.