Preconditioning and postconditioning: The essential role of the mitochondrial permeability transition pore

Cardiovascular Research

Volumn 75, Issue 3, 2007, Pages 530-535

  Lim, Shiang Y ^a   Davidson, Sean M ^a   Hausenloy, Derek J ^a   Yellon, Derek M ^a  

^a UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

Author keywords

Ischemia; Mitochondria; Preconditioning; Reperfusion

Indexed keywords

BRADYKININ; CYCLOPHILIN D; CYCLOSPORIN A; DIAZOXIDE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; SANGLIFEHRIN A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CONTROLLED STUDY; FEMALE; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; ISCHEMIC PRECONDITIONING; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY;

ANIMALS; BRADYKININ; CYCLOPHILINS; CYCLOSPORINE; DIAZOXIDE; ENZYME INHIBITORS; FEMALE; ISCHEMIC PRECONDITIONING, MYOCARDIAL; LACTONES; MALE; MICE; MICE, KNOCKOUT; MITOCHONDRIA, HEART; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MODELS, ANIMAL; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; SPIRO COMPOUNDS; VASODILATOR AGENTS;

EID: 34447507839     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2007.04.022     Document Type: Article

References (21)

1. Murry C.E., Jennings R.B., and Reimer K.A. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74 (1986) 1124-1136
2. Zhao Z.Q., Corvera J.S., Halkos M.E., Kerendi F., Wang N.P., Guyton R.A., et al. Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning. Am J Physiol Heart Circ Physiol 285 (2003) H579-H588
3. Staat P., Rioufol G., Piot C., Cottin Y., Cung T.T., L'Huillier I., et al. Postconditioning the human heart. Circulation 112 (2005) 2143-2148
4. Griffiths E.J., and Halestrap A.P. Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion. Biochem J 307 Pt 1 (1995) 93-98
5. Hausenloy D.J., Duchen M.R., and Yellon D.M. Inhibiting mitochondrial permeability transition pore opening at reperfusion protects against ischaemia-reperfusion injury. Cardiovasc Res 60 (2003) 617-625
6. Hausenloy D.J., Yellon D.M., Mani-Babu S., and Duchen M.R. Preconditioning protects by inhibiting the mitochondrial permeability transition. Am J Physiol Heart Circ Physiol 287 (2004) H841-H849
7. Javadov S.A., Clarke S., Das M., Griffiths E.J., Lim K.H., and Halestrap A.P. Ischaemic preconditioning inhibits opening of mitochondrial permeability transition pores in the reperfused rat heart. J Physiol 549 (2003) 513-524
8. Juhaszova M., Zorov D.B., Kim S.H., Pepe S., Fu Q., Fishbein K.W., et al. Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore. J Clin Invest 113 (2004) 1535-1549
9. Argaud L., Gateau-Roesch O., Raisky O., Loufouat J., Robert D., and Ovize M. Postconditioning inhibits mitochondrial permeability transition. Circulation 111 (2005) 194-197
10. Bopassa J.C., Ferrera R., Gateau-Roesch O., Couture-Lepetit E., and Ovize M. PI 3-kinase regulates the mitochondrial transition pore in controlled reperfusion and postconditioning. Cardiovasc Res 69 (2006) 178-185
11. Baines C.P., Kaiser R.A., Sheiko T., Craigen W.J., and Molkentin J.D. Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death. Nat Cell Biol (2007) 10.1038/ncb1575
12. Kokoszka J.E., Waymire K.G., Levy S.E., Sligh J.E., Cai J., Jones D.P., et al. The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore. Nature 427 (2004) 461-465
13. Basso E., Fante L., Fowlkes J., Petronilli V., Forte M.A., and Bernardi P. Properties of the permeability transition pore in mitochondria devoid of cyclophilin D. J Biol Chem 280 (2005) 18558-18561
14. Baines C.P., Kaiser R.A., Purcell N.H., Blair N.S., Osinska H., Hambleton M.A., et al. Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death. Nature 434 (2005) 658-662
15. Nakagawa T., Shimizu S., Watanabe T., Yamaguchi O., Otsu K., Yamagata H., et al. Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature 434 (2005) 652-658
16. Schinzel A.C., Takeuchi O., Huang Z., Fisher J.K., Zhou Z., Rubens J., et al. Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia. Proc Natl Acad Sci U S A 102 (2005) 12005-12010
17. Crompton M., Costi A., and Hayat L. Evidence for the presence of a reversible Ca-2+-dependent pore activated by oxidative stress in heart-mitochondria. Biochem J 245 (1987) 915-918
18. Crompton M., Ellinger H., and Costi A. Inhibition by cyclosporin-A of a Ca-2+-dependent pore in heart-mitochondria activated by inorganic-phosphate and oxidative stress. Biochem J 255 (1988) 357-360
19. Davidson S.M., Hausenloy D., Duchen M.R., and Yellon D.M. Signalling via the reperfusion injury signalling kinase (RISK) pathway links closure of the mitochondrial permeability transition pore to cardioprotection. Int J Biochem Cell Biol 38 (2006) 414-419
20. 2 inhibit the mitochondrial permeability transition. J Biol Chem 281 (2006) 20801-20808
21. Hausenloy D., Wynne A., Duchen M., and Yellon D. Transient mitochondrial permeability transition pore opening mediates preconditioning-induced protection. Circulation 109 (2004) 1714-1717