Persistent beneficial effect of postconditioning against infarct size: Role of mitochondrial KATP channels during reperfusion

Basic Research in Cardiology

Volumn 103, Issue 5, 2008, Pages 472-484

  Mykytenko, James ^a   Reeves, James G ^a   Kin, Hajime ^a   Wang, Ning Ping ^a   Zatta, Amanda J ^a   Jiang, Rong ^a   Guyton, Robert A ^a   Vinten Johansen, Jakob ^a   Zhao, Zhi Qing ^a  

^a EMORY UNIVERSITY   (United States)

Author keywords

Infarct size; KATPchannels; Mitochondrial permeability transition pore; Postconditioning; Reperfusion injury

Indexed keywords

5 HYDROXYDECANOIC ACID; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CALCEIN; CLAMIKALANT; CREATINE KINASE; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.1; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; OXYGEN; TETRAMETHYLRHODAMINE METHYL ESTER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA PRESSURE; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DOG; EMBRYO; ENZYME ACTIVITY; FEMALE; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE BLOOD FLOW; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; HEART RATE; HYPOTHESIS; HYPOXIA; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; OUTCOME ASSESSMENT; PROTEIN EXPRESSION; RAT; REOXYGENATION; SARCOLEMMA; SYSTOLIC BLOOD PRESSURE; TREATMENT OUTCOME; UPREGULATION;

ANIMALS; CELL DEATH; CORONARY CIRCULATION; CREATINE KINASE; DISEASE MODELS, ANIMAL; DOGS; FEMALE; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MALE; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MYOCARDIAL CONTRACTION; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; POTASSIUM CHANNELS, INWARDLY RECTIFYING; TACHYCARDIA, VENTRICULAR;

EID: 50249146803     PISSN: 03008428     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00395-008-0731-2     Document Type: Article

References (58)

1. Abas L, Bogoyevitch MA, Guppy M (2000) Mitochondrial ATP production is necessary for activation of the extracellular-signal-regulated kinases during ischaemia/reperfusion in rat myocyte-derived H9c2 cells. Biochem J 349:119-126
2. Akao M, Teshima Y, Marban E (2002) Antiapoptotic effect of nicorandil mediated by mitochondrial ATP-sensitive potassium channels in cultured cardiac myocytes. J Am Coll Cardiol 40:803-810
3. Argaud L, Gateau-Roesch O, Raisky O, Loufouat J, Robert D, Ovize M (2005) Post-conditioning inhibits mitochondrial permeability transition. Circulation 111:194-197
4. Becker LB (2004) New concepts in reactive oxygen species and cardiovascular reperfusion physiology. Cardiovas Res 61:461-470
5. ATP channel in rat brain nonsynaptosomal mitochondria. J Physiol 568:47-59
6. Cohen MV, Yang XM, Downey JM (2007) The pH hypothesis of postconditioning: Staccato reperfusion reintroduces oxygen and perpetuates myocardial acidosis. Circulation 115:1895-1903
7. Darling CE, Solari PB, Smith CS, Furman MI, Przyklenk K (2007) 'Postconditioning' the human heart: Multiple balloon inflations during primary angioplasty may confer cardioprotection. Basic Res Cardiol 102:274-278
8. Downey JM, Cohen MV (2006) A really radical observation - a comment on Penna et al. Basic Res Cardiol 101:180-189
9. Galagudza M, Kurapeev D, Minasian S, Valen G, Vaage J (2004) Ischemic postconditioning: Brief ischemia during reperfusion converts persistent ventricular fibrillation into regular rhythm. Eur J Cardiothorac Surg 25:1006-1010
10. Gogelein H, Englert HC, Kotzan A, Hack R, Lehr KH, Seiz W, Becker RHA, Sultan E, Scholkens BA, Busch AE (2000) HMR 1098: An inhibitor of cardiac ATP-sensitive potassium channels. Cardiovasc Drug Rev 18:157-174
11. Gok S, Vural K, Sekuri C, Onur R, Tezcan A, Izanli A (2006) Effects of the blockade of cardiac sarcolemmal ATP-sensitive potassium channels on arrhythmias and coronary flow in ischemia-reperfusion model in isolated rat hearts. Vascul Pharmacol 44:197-205
12. + channels and myocardial preconditioning. Circ Res 84:973-979
13. Halestrap AP, Clarke SJ, Javadov SA (2004) Mitochondrial permeability transition pore opening during myocardial reperfusion - a target for cardioprotection. Cardiovasc Res 61:372-385
14. Halkos ME, Kerendi F, Corvera JS, Wang NP, Kin H, Payne CS, Sun H-Y, Guyton RA, Vinten-Johansen J, Zhao ZQ (2004) Myocardial protection with postconditioning is not enhanced by ischemic preconditioning. Ann Thorac Surg 78:961-969
15. Hausenloy DJ, Wynne AM, Yellon DM (2007) Ischemic preconditioning targets the reperfusion phase. Basic Res Cardiol 102:445-452
16. Heinzel FR, Luo Y, Dodoni G, Boengler K, Petrat F, Di Lisa F, de Groot H, Schulz R, Heusch G (2006) Formation of reactive oxygen species at increased contraction frequency in rat cardiomyocytes. Cardiovasc Res 71:374-382
17. Heusch G, Buchert A, Feldhaus S, Schulz R (2006) No loss of cardioprotection by postconditioning in connexin 43-deficient mice. Basic Res Cardiol 101:354-356
18. Iliodromitis EK, Georgiadis M, Cohen MV, Downey JM, Bofilis E, Kremastinos DT (2006) Protection from postconditioning depends on the number of short ischemic insults in anesthetized pigs. Basic Res Cardiol 101:502-507
19. Jung O, Englert HC, Jung W, Gogelein H, Scholkens BA, Busch AE, Linz W (2000) The K(ATP) channel blocker HMR 1883 does not abolish the benefit of ischemic preconditioning on myocardial infarct mass in anesthetized rabbits. Naunyn Schmiedebergs Arch Pharmacol 361:445-451
20. Kin H, Zatta AJ, Lofye MT, Amerson BS, Halkos ME, Kerendi F, Zhao ZQ, Guyton RA, Headrick JP, Vinten-Johansen J (2005) Postconditioning reduces infarct size via adenosine receptor activation by endogenous adenosine. Cardiovasc Res 67:124-133
21. Kin H, Zhao ZQ, Sun H-Y, Wang NP, Corvera JS, Halkos ME, Kerendi F, Guyton RA, Vinten-Johansen J (2004) Postconditioning attenuates myocardial ischemia-reperfusion injury by inhibiting events in the early minutes of reperfusion. Cardiovasc Res 62:74-85
22. Kloner RA, Dow J, Bhandari A (2006) Postconditioning markedly attenuates ventricular arrhythmias after ischemia-reperfusion. J Cardiovasc Pharmacol Ther 11:55-63
23. + channels. J Mol Cell Cardiol 35:1339-1347
24. ATP channel opening attenuates myocardial stunning by reducing calcium influx. Mol Cell Biochem 236:53-61
25. ATP channel opener diazoxide protects cardiac myocytes during metabolic inhibition without causing mitochondrial depolarization or flavoprotein oxidation. Br J Pharmacol 134:535-542
26. Lawrence KM, Chanalaris A, Scarabelli T, Hubank M, Pasini E, Townsend PA, Comini L, Ferrari R, Tinker A, Stephanou A, Knight RA, Latchman DS (2002) K(ATP) channel gene expression is induced by urocortin and mediates its cardioprotective effect. Circulation 106:1556-1562
27. Lee TM, Su SF, Tsai CC, Lee YT, Tsai CH (2000) Cardioprotective effects of 17 beta-estradiol produced by activation of mitochondrial ATP-sensitive K(+)Channels in canine hearts. J Mol Cell Cardiol 32:1147-1158
28. ATP channel enhances adenosine-induced cardioprotection. Biochem J 336:337-343
29. Light PE, Bladen C, Winkfein RJ, Walsh MP, French RJ (2000) Molecular basis of protein kinase C-induced activation of ATP-sensitive potassium channels. Proc Natl Acad Sci USA 97:9058-9063
30. + channels. A possible mechanistic link to ischemic preconditioning. Circ Res 79:399-406
31. Liu Y, Ren G, O'Rourke B, Marban E, Seharaseyon J (2001) Pharmacological comparison of native mitochondrial K(ATP) channels with molecularly defined surface K(ATP) channels. Mol Pharmacol 59:225-230
32. Liu Y, Yang XM, Iliodromitis EK, Kremastinos DT, Dost T, Cohen MV, Downey JM (2008) Redox signaling at reperfusion is required for protection from ischemic preconditioning but not from a direct PKC activator. Basic Res Cardiol 103:54-59
33. Luo W, Li B, Lin G, Huang R (2007) Postconditioning in cardiac surgery for tetralogy of fallot. J Thorac Cardiovasc Surg 133:1373-1374
34. McCully JD, Wakiyama H, Cowan DB, Federman M, Parker RA, Levitsky S (2002) Diazoxide amelioration of myocardial injury and mitochondrial damage during cardiac surgery. Ann Thorac Surg 74:2138-2146
35. Miki T, Suzuki M, Shibasaki T, Uemura H, Sato T, Yamaguchi K, Koseki H, Iwanaga T, Nakaya H, Seino S (2002) Mouse model of Prinzmetal angina by disruption of the inward rectifier Kir6.1. Nat Med 8:466-472
36. Mykytenko J, Kerendi F, Reeves JG, Kin H, Zatta AJ, Jiang R, Guyton RA, Vinten-Johansen J, Zhao ZQ (2007) Long-term inhibition of myocardial infarction by postconditioning during reperfusion. Basic Res Cardiol 102:90-100
37. + channel and protein kinase C activation. Basic Res Cardiol 101:180-189
38. Piper HM, Schafer AC (2004) The first minutes of reperfusion: A window of opportunity for cardioprotection. Cardiovasc Res 61:365-371
39. ATP channel antagonism on basal, stimulated, and ischaemic myocardial function in in vivo failing canine heart. Br J Pharmacol 135:657-662
40. (ATP) channels in ischemic preconditioning of the canine heart. Am J Physiol Heart Circ Physiol 280:H256-H263
41. ATP channels in ischemic cardioprotection. Circulation 101:2418-2423
42. Singh H, Hudman D, Lawrence CL, Rainbow RD, Lodwick D, Norman RI (2003) Distribution of Kir6.0 and SUR2 ATP-sensitive potassium channel subunits in isolated ventricular myocytes. J Mol Cell Cardiol 35:445-459
43. Staat P, Rioufol G, Piot C, Cottin Y, Cung TT, L'Huillier I, Aupetit J-F, Bonnefoy E, Finet G, Andre-Fouet X, Ovize MM (2005) Postconditioning the human heart. Circulation 112:2143-2148
44. 2+ overload. Am J Physiol Heart Circ Physiol 288:H1900-H1908
45. + exchanger in hypoxia/re-oxygenation-induced neonatal rat cardiomyocyte apoptosis. Eur J Pharmacol 486:121-131
46. Suzuki M, Li RA, Miki T, Uemura H, Sakamoto N, Ohmoto-Sekine Y, Tamagawa M, Ogura T, Seino S, Marban E, Nakaya H (2001) Functional roles of cardiac and vascular ATP-sensitive potassium channels clarified by Kir6.2-knockout mice. Circ Res 88:570-577
47. (ATP) channels. Naunyn Schmiedebergs Arch Pharmacol 364:226-232
48. Thibault H, Piot C, Staat P, Bontemps L, Sportouch C, Rioufol G, Cung TT, Bonnefoy E, Angoulvant D, Aupetit JF, Finet G, Andre-Fouet X, Macia JC, Raczka F, Rossi R, Itti R, Kirkorian G, Derumeaux G, Ovize M (2008) Long-term benefit of postconditioning. Circulation 117:1037-1044
49. (ATP) channels activated by 17 beta-estradiol on reperfusion arrhythmias and infarct sizes in canine hearts. J Pharmacol Exp Ther 301:234-240
50. Vinten-Johansen J, Zhao ZQ, Zatta AJ, Kin H, Halkos ME, Kerendi F (2005) Postconditioning - a new link in nature's armor against myocardial ischemia-reperfusion injury. Basic Res Cardiol 100:295-310
51. Wakiyama H, Cowan DB, Toyoda Y, Federman M, Levitsky S, McCully JD (2002) Selective opening of mitochondrial ATP-sensitive potassium channels during surgically induced myocardial ischemia decreases necrosis and apoptosis. Eur J Cardiothorac Surg 21:424-433
52. Yang X-M, Proctor JB, Cui L, Krieg T, Downey JM, Cohen MV (2004) Multiple, brief coronary occlusions during early reperfusion protect rabbit hearts by targeting cell signaling pathways. J Am Coll Cardiol 44:1103-1110
53. Yang XC, Liu Y, Wang LF, Cui L, Wang T, Ge YG, Wang HS, Li WM, Xu L, Ni ZH, Liu SH, Zhang L, Jia HM, Vinten-Johansen J, Zhao ZQ (2007) Reduction in myocardial infarct size by postconditioning in patients after percutaneous coronary intervention. J Invasive Cardiol 19:424-430
54. Yang XM, Philipp S, Downey JM, Cohen MV (2005) Postconditioning's protection is not dependent on circulating blood factors or cells but involves adenosine receptors and requires PI3-kinase and guanylyl cyclase activation. Basic Res Cardiol 100:57-63
55. Yin Z, Milatovic D, Aschner JL, Syversen T, Rocha JB, Souza DO, Sidoryk M, Albrecht J, Aschner M (2007) Methylmercury induces oxidative injury, alterations in permeability and glutamine transport in cultured astrocytes. Brain Res 1131:1-10
56. Zatta AJ, Kin H, Lee G, Wang N, Jiang R, Lust R, Reeves JG, Mykytenko J, Guyton RA, Zhao ZQ, Vinten-Johansen J (2006) Infarct-sparing effect of myocardial postconditioning is dependent on protein kinase C signalling. Cardiovasc Res 70:315-324
57. Zhao Z-Q, Corvera JS, Halkos ME, Kerendi F, Wang NP, Guyton RA, Vinten-Johansen J (2003) Inhibition of myocardial injury by ischemic postconditioning during reperfusion: Comparison with ischemic preconditioning. Am J Physiol Heart Circ Physiol 285:H579-H588
58. Zhao Z-Q, Nakamura M, Wang N-P, Velez DA, Hewan-Lowe KO, Guyton RA, Vinten-Johansen J (2000) Dynamic progression of contractile and endothelial dysfunction and infarct extension in the late phase of reperfusion. J Surg Res 94:1-12