Protein array reveals differentially expressed proteins in subcutaneous adipose tissue in obesity

Obesity

Volumn 15, Issue 10, 2007, Pages 2396-2406

  Škopková, Martina ^a   Penesová, Adela ^a   Sell, Henrike ^b   Rádiková, Žofia ^a   Vlček, Miroslav ^a   Imrich, Richard ^a   Koška, Juraj ^a   Ukropec, Jozef ^a   Eckel, Jürgen ^b   Klimeš, Iwar ^a   Gašperíková, Daniela ^a  

^a INSTITUTE OF EXPERIMENTAL ENDOCRINOLOGY   (Slovakia)

^b LEIBNIZ CENTER FOR DIABETES RESEARCH AT HEINRICH HEINE UNIVERSITY DÜSSELDORF   (Germany)

Author keywords

Cytokines; Inflammation; Insulin resistance; Protein

Indexed keywords

PROTEIN;

ADULT; ARTICLE; FEMALE; GENETICS; HUMAN; MALE; METABOLISM; OBESITY; PROTEIN MICROARRAY; SUBCUTANEOUS FAT;

ADULT; FEMALE; HUMANS; MALE; OBESITY; PROTEIN ARRAY ANALYSIS; PROTEINS; SUBCUTANEOUS FAT;

EID: 35648998408     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2007.285     Document Type: Article

References (8)

1. Rajala MW, Scherer PE. Minireview. The adipocyte: at the crossroads of energy homeostasis, inflammation, and atherosclerosis. Endocrinology. 2003;144:3765-73.
2. Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest. 2003;112:1796-808.
3. Xu H, Barnes GT, Yang Q, et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest. 2003;112:1821-30.
4. Wellen KE, Hotamisligil GS. Inflammation, stress, and diabetes. J Clin Invest. 2005;115:1111-9.
5. Kolb H, Mandrup-Poulsen T. An immune origin of type 2 diabetes? Diabetologia. 2005;48:1038-50.
6. Kershaw EE, Flier JS. Adipose tissue as an endocrine organ. J Clin Endocrinol Metab. 2004;89:2548-56.
7. Scherer PE. Adipose tissue: from lipid storage compartment to endocrine organ. Diabetes. 2006;55:1537-45.
8. Guerre-Millo M. Adipose tissue and adipokines: for better or worse. Diabetes Metab. 2004;30:13-9.