-
1
-
-
0036463405
-
A matter of life and death
-
Green DG, Evan GI. A matter of life and death. Cancer Cell 2002;1:19-30.
-
(2002)
Cancer Cell
, vol.1
, pp. 19-30
-
-
Green, D.G.1
Evan, G.I.2
-
2
-
-
0036547417
-
Death and anti-death: Tumour resistance to apoptosis
-
Igney FH, Krammer PH. Death and anti-death: tumour resistance to apoptosis. Nat Rev Cancer 2002;2:277-88.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 277-288
-
-
Igney, F.H.1
Krammer, P.H.2
-
3
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
4
-
-
0037069929
-
Chemotherapy: Targeting the mitochondrial cell death pathway
-
Debatin KM, Poncet D, Kroemer G. Chemotherapy: targeting the mitochondrial cell death pathway. Oncogene 2002;21:8786-803.
-
(2002)
Oncogene
, vol.21
, pp. 8786-8803
-
-
Debatin, K.M.1
Poncet, D.2
Kroemer, G.3
-
5
-
-
0344393783
-
Alterations in the apoptotic machinery and their potential role in anticcancer drug resistance
-
Kaufmann SH, Vaux DL. Alterations in the apoptotic machinery and their potential role in anticcancer drug resistance. Oncogene 2003;22:7414-30.
-
(2003)
Oncogene
, vol.22
, pp. 7414-7430
-
-
Kaufmann, S.H.1
Vaux, D.L.2
-
6
-
-
0036144378
-
Caspases: Opening the boxes and interpreting the arrows
-
Salvesen GS. Caspases: opening the boxes and interpreting the arrows. Cell Death Differ 2002;9:3-5.
-
(2002)
Cell Death Differ
, vol.9
, pp. 3-5
-
-
Salvesen, G.S.1
-
7
-
-
0036205587
-
Mechanisms of caspase activation and inhibition during apoptosis
-
Shi Y. Mechanisms of caspase activation and inhibition during apoptosis. Mol Cell 2002;9:459-70.
-
(2002)
Mol Cell
, vol.9
, pp. 459-470
-
-
Shi, Y.1
-
8
-
-
0037211252
-
Role of XIAP in the malignant phenotype of transitional cell cancer (TCC) and therapeutic activity of XIAP antisense oligonucleotides against multidrug-resistant TCC in vitro
-
Bilim V, Kasahara T, Hara N, Takahashi K, Tomita Y. Role of XIAP in the malignant phenotype of transitional cell cancer (TCC) and therapeutic activity of XIAP antisense oligonucleotides against multidrug-resistant TCC in vitro. Int J Cancer 2003;103:29-37.
-
(2003)
Int J Cancer
, vol.103
, pp. 29-37
-
-
Bilim, V.1
Kasahara, T.2
Hara, N.3
Takahashi, K.4
Tomita, Y.5
-
9
-
-
20244362748
-
Flavopiridol downregulates antiapoptotic proteins and sensitizes human breast cancer cells to epothilone B-induced apoptosis
-
Wittmann S, Bali P, Donapaty S, Nimmanapalli R, Guo F, Yamaguchi H, Huang M, Jove R, Wang HG, Bhalla K. Flavopiridol downregulates antiapoptotic proteins and sensitizes human breast cancer cells to epothilone B-induced apoptosis. Cancer Res 2003;63:93-99.
-
(2003)
Cancer Res
, vol.63
, pp. 93-99
-
-
Wittmann, S.1
Bali, P.2
Donapaty, S.3
Nimmanapalli, R.4
Guo, F.5
Yamaguchi, H.6
Huang, M.7
Jove, R.8
Wang, H.G.9
Bhalla, K.10
-
10
-
-
0037478904
-
Antisense oligonucleotides targeting XIAP induce apoptosis and enhance chemotherapeutic activity against human lung cancer cells in vitro and in vivo
-
Hu Y, Cherton-Horvat G, Dragowska V, Baird S, Korneluk RG, Durkin JP, Mayer LD, LaCasse EC. Antisense oligonucleotides targeting XIAP induce apoptosis and enhance chemotherapeutic activity against human lung cancer cells in vitro and in vivo. Clin Cancer Res 2003;9:2826-36.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 2826-2836
-
-
Hu, Y.1
Cherton-Horvat, G.2
Dragowska, V.3
Baird, S.4
Korneluk, R.G.5
Durkin, J.P.6
Mayer, L.D.7
LaCasse, E.C.8
-
11
-
-
0037062585
-
Molecular targeting of inhibitor of apoptosis proteins based on small molecule mimics of natural binding partners
-
Kipp RA, Case MA, Wist AD, Cresson CM, Carrell M, Griner E, Wiita A, Albiniak PA, Chai J, Shi Y, Semmelhack MF, McLendon GL. Molecular targeting of inhibitor of apoptosis proteins based on small molecule mimics of natural binding partners. Biochemistry 2002;41:7344-49.
-
(2002)
Biochemistry
, vol.41
, pp. 7344-7349
-
-
Kipp, R.A.1
Case, M.A.2
Wist, A.D.3
Cresson, C.M.4
Carrell, M.5
Griner, E.6
Wiita, A.7
Albiniak, P.A.8
Chai, J.9
Shi, Y.10
Semmelhack, M.F.11
McLendon, G.L.12
-
12
-
-
9144234685
-
Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity
-
Schimmer AD, Welsh K, Pinilla C, Wang Z, Krajewska M, Bonneau MJ, Pedersen IM, Kitada S, Scott FL, Bailly-Maitre B, Glinsky G, Scudiero D, et al. Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity. Cancer Cell 2004;5:25-35.
-
(2004)
Cancer Cell
, vol.5
, pp. 25-35
-
-
Schimmer, A.D.1
Welsh, K.2
Pinilla, C.3
Wang, Z.4
Krajewska, M.5
Bonneau, M.J.6
Pedersen, I.M.7
Kitada, S.8
Scott, F.L.9
Bailly-Maitre, B.10
Glinsky, G.11
Scudiero, D.12
-
13
-
-
0035156848
-
Identification of XAF1 as an antagonist of XIAP anti-Caspase activity
-
Liston P, Fong WG, Kelly NL, Toji S, Miyazaki T, Conte D, Tamai K, Craig CG, McBurney MW, Korneluk RG. Identification of XAF1 as an antagonist of XIAP anti-Caspase activity. Nat Cell Biol 2001;3:128-33.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 128-133
-
-
Liston, P.1
Fong, W.G.2
Kelly, N.L.3
Toji, S.4
Miyazaki, T.5
Conte, D.6
Tamai, K.7
Craig, C.G.8
McBurney, M.W.9
Korneluk, R.G.10
-
14
-
-
0034700495
-
Structural basis for binding of Smac/DIABLO to the XIAP BIR 3 domain
-
Liu Z, Sun C, Olejniczak ET, Meadows RP, Betz SF, Oost T, Herrmann J, Wu JC, Fesik SW. Structural basis for binding of Smac/DIABLO to the XIAP BIR 3 domain. Nature 2000;408:1004-8.
-
(2000)
Nature
, vol.408
, pp. 1004-1008
-
-
Liu, Z.1
Sun, C.2
Olejniczak, E.T.3
Meadows, R.P.4
Betz, S.F.5
Oost, T.6
Herrmann, J.7
Wu, J.C.8
Fesik, S.W.9
-
15
-
-
0034672506
-
Expression and genetic analysis of XIAP-associated factor 1 (XAF1) in cancer cell lines
-
Fong WG, Liston P, Rajcan-Separovic E, St Jean M, Craig C, Korneluk RG. Expression and genetic analysis of XIAP-associated factor 1 (XAF1) in cancer cell lines. Genomics 2000;70:113-22.
-
(2000)
Genomics
, vol.70
, pp. 113-122
-
-
Fong, W.G.1
Liston, P.2
Rajcan-Separovic, E.3
St Jean, M.4
Craig, C.5
Korneluk, R.G.6
-
16
-
-
0242442595
-
Hypermethylation of XIAP-associated factor 1, a putative tumor suppressor gene from the 17p13.2 locus, in human gastric adenocarcinomas
-
Byun DS, Cho K, Ryu BK, Lee MG, Kang MJ, Kim HR, Chi SG. Hypermethylation of XIAP-associated factor 1, a putative tumor suppressor gene from the 17p13.2 locus, in human gastric adenocarcinomas. Cancer Res 2003;63:7068-75.
-
(2003)
Cancer Res
, vol.63
, pp. 7068-7075
-
-
Byun, D.S.1
Cho, K.2
Ryu, B.K.3
Lee, M.G.4
Kang, M.J.5
Kim, H.R.6
Chi, S.G.7
-
17
-
-
16344392960
-
Low expression of XIAP-associated factor 1 in human colorectal cancers
-
Ma TL, Ni PH, Zhong J, Tan JH, Qiao MM, Jiang SH. Low expression of XIAP-associated factor 1 in human colorectal cancers. Chin J Dig Dis 2005;6:10-14.
-
(2005)
Chin J Dig Dis
, vol.6
, pp. 10-14
-
-
Ma, T.L.1
Ni, P.H.2
Zhong, J.3
Tan, J.H.4
Qiao, M.M.5
Jiang, S.H.6
-
18
-
-
33845645132
-
Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers
-
Zou B, Chim CS, Zeng H, Leung SY, Yang Y, Tu SP, Lin MC, Wang J, He H, Jiang SH, Sun YW, Yu LF, et al. Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers. Gastroenterology 2006;131:1835-43.
-
(2006)
Gastroenterology
, vol.131
, pp. 1835-1843
-
-
Zou, B.1
Chim, C.S.2
Zeng, H.3
Leung, S.Y.4
Yang, Y.5
Tu, S.P.6
Lin, M.C.7
Wang, J.8
He, H.9
Jiang, S.H.10
Sun, Y.W.11
Yu, L.F.12
-
19
-
-
34547258025
-
Gene expression and promoter methylation of the XIAP-associated Factor 1 in renal cell carcinomas: Correlations with pathology and outcome
-
Kempkensteffen C, Hinz S, Schrader M, Christoph F, Magheli A, Krause H, Schostak M, Miller K, Weikert S. Gene expression and promoter methylation of the XIAP-associated Factor 1 in renal cell carcinomas: correlations with pathology and outcome. Cancer Lett 2007;254:227-35.
-
(2007)
Cancer Lett
, vol.254
, pp. 227-235
-
-
Kempkensteffen, C.1
Hinz, S.2
Schrader, M.3
Christoph, F.4
Magheli, A.5
Krause, H.6
Schostak, M.7
Miller, K.8
Weikert, S.9
-
20
-
-
34249871106
-
The role of XAF1 in cancer
-
Plenchette S, Cheung HH, Fong WG, LaCasse EC, Korneluk RG. The role of XAF1 in cancer. Curr Opin Investig Drugs 2007;8:469-76.
-
(2007)
Curr Opin Investig Drugs
, vol.8
, pp. 469-476
-
-
Plenchette, S.1
Cheung, H.H.2
Fong, W.G.3
LaCasse, E.C.4
Korneluk, R.G.5
-
21
-
-
10744232690
-
Suppression of survivin expression inhibits in vivo tumorigenicity and angiogenesis in gastric cancer
-
Tu SP, Jiang XH, Lin MC, Cui JT, Yang Y, Lum CT, Zou B, Zhu YB, Jiang SH, Wong WM, Chan AO, Yuen MF, et al. Suppression of survivin expression inhibits in vivo tumorigenicity and angiogenesis in gastric cancer. Cancer Res 2003;63:7724-32.
-
(2003)
Cancer Res
, vol.63
, pp. 7724-7732
-
-
Tu, S.P.1
Jiang, X.H.2
Lin, M.C.3
Cui, J.T.4
Yang, Y.5
Lum, C.T.6
Zou, B.7
Zhu, Y.B.8
Jiang, S.H.9
Wong, W.M.10
Chan, A.O.11
Yuen, M.F.12
-
22
-
-
14944359615
-
Gene therapy for colon cancer by adeno-associated viral vector-mediated transfer of survivin Cys84Ala mutant
-
Tu SP, Cui JT, Liston P, Huajiang X, Xu R, Lin MC, Zhu YB, Zou B, Ng SS, Jiang SH, Xia HH, Wong WM, et al. Gene therapy for colon cancer by adeno-associated viral vector-mediated transfer of survivin Cys84Ala mutant. Gastroenterology 2005;128:361-75.
-
(2005)
Gastroenterology
, vol.128
, pp. 361-375
-
-
Tu, S.P.1
Cui, J.T.2
Liston, P.3
Huajiang, X.4
Xu, R.5
Lin, M.C.6
Zhu, Y.B.7
Zou, B.8
Ng, S.S.9
Jiang, S.H.10
Xia, H.H.11
Wong, W.M.12
-
23
-
-
0037047285
-
Identification of X-linked inhibitor of apoptosis-associated factor-1 as an interferon-stimulated gene that augments TRAIL Apo2L-induced apoptosis
-
Leaman DW, Chawla-Sarkar M, Vyas K, Reheman M, Tamai K, Toji S, Borden EC. Identification of X-linked inhibitor of apoptosis-associated factor-1 as an interferon-stimulated gene that augments TRAIL Apo2L-induced apoptosis. J Biol Chem 2002;277:28504-11.
-
(2002)
J Biol Chem
, vol.277
, pp. 28504-28511
-
-
Leaman, D.W.1
Chawla-Sarkar, M.2
Vyas, K.3
Reheman, M.4
Tamai, K.5
Toji, S.6
Borden, E.C.7
-
24
-
-
0142188706
-
Coexistence of high levels of apoptotic signaling and inhibitor of apoptosis proteins in human tumor cells: Implication for cancer specific therapy
-
Yang L, Cao Z, Yan H, Wood WC. Coexistence of high levels of apoptotic signaling and inhibitor of apoptosis proteins in human tumor cells: implication for cancer specific therapy. Cancer Res 2003;63:6815-24.
-
(2003)
Cancer Res
, vol.63
, pp. 6815-6824
-
-
Yang, L.1
Cao, Z.2
Yan, H.3
Wood, W.C.4
-
25
-
-
33646252040
-
Xaf1 can cooperate with TNFalpha in the induction of apoptosis, independently of interaction with XIAP
-
Xia Y, Novak R, Lewis J, Duckett CS, Phillips AC. Xaf1 can cooperate with TNFalpha in the induction of apoptosis, independently of interaction with XIAP. Mol Cell Biochem 2006;286:67-76.
-
(2006)
Mol Cell Biochem
, vol.286
, pp. 67-76
-
-
Xia, Y.1
Novak, R.2
Lewis, J.3
Duckett, C.S.4
Phillips, A.C.5
-
26
-
-
34249908513
-
XAF1 mediates tumor necrosis factoralpha-induced apoptosis and X-linked inhibitor of apoptosis cleavage by acting through the mitochondrial pathway
-
Straszewski-Chavez SL, Visintin IP, Karassina N, Los G, Liston P, Halaban R, Fadiel A, Mor G. XAF1 mediates tumor necrosis factoralpha-induced apoptosis and X-linked inhibitor of apoptosis cleavage by acting through the mitochondrial pathway. J Biol Chem 2007;282:13059-72.
-
(2007)
J Biol Chem
, vol.282
, pp. 13059-13072
-
-
Straszewski-Chavez, S.L.1
Visintin, I.P.2
Karassina, N.3
Los, G.4
Liston, P.5
Halaban, R.6
Fadiel, A.7
Mor, G.8
-
27
-
-
0035666958
-
Cell cycle arrest is sufficient for p53-mediated tumor regression
-
Dubrez L, Coll JL, Hurbin A, de Fraipont F, Lantejoul S, Favrot MC. Cell cycle arrest is sufficient for p53-mediated tumor regression. Gene Ther 2001;8:1705-12.
-
(2001)
Gene Ther
, vol.8
, pp. 1705-1712
-
-
Dubrez, L.1
Coll, J.L.2
Hurbin, A.3
de Fraipont, F.4
Lantejoul, S.5
Favrot, M.C.6
-
28
-
-
0036510163
-
BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage
-
Yarden RI, Pardo-Reoyo S, Sgagias M, Cowan KH, Brody LC. BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage. Nat Genet 2002;30:285-9.
-
(2002)
Nat Genet
, vol.30
, pp. 285-289
-
-
Yarden, R.I.1
Pardo-Reoyo, S.2
Sgagias, M.3
Cowan, K.H.4
Brody, L.C.5
-
29
-
-
8844251504
-
Tumor suppressor RASSF1A is a microtubule-binding protein that stabilizes microtubules and induces G2/M arrest
-
Rong R, Jin W, Zhang J, Sheikh MS, Huang Y. Tumor suppressor RASSF1A is a microtubule-binding protein that stabilizes microtubules and induces G2/M arrest. Oncogene 2004;23:8216-30.
-
(2004)
Oncogene
, vol.23
, pp. 8216-8230
-
-
Rong, R.1
Jin, W.2
Zhang, J.3
Sheikh, M.S.4
Huang, Y.5
-
30
-
-
33748922416
-
Promoter CpG hypermethylation and downregulation of XAF1 expression in human urogenital malignancies: Implication for attenuated p53 response to apoptotic stresses
-
Lee MG, Huh JS, Chung SK, Lee JH, Byun DS, Ryu BK, Kang MJ, Chae KS, Lee SJ, Lee CH, Kim JI, Chang SG, et al. Promoter CpG hypermethylation and downregulation of XAF1 expression in human urogenital malignancies: implication for attenuated p53 response to apoptotic stresses. Oncogene 2006;25:5807-22.
-
(2006)
Oncogene
, vol.25
, pp. 5807-5822
-
-
Lee, M.G.1
Huh, J.S.2
Chung, S.K.3
Lee, J.H.4
Byun, D.S.5
Ryu, B.K.6
Kang, M.J.7
Chae, K.S.8
Lee, S.J.9
Lee, C.H.10
Kim, J.I.11
Chang, S.G.12
-
31
-
-
33646411773
-
Switch to full-length of XAF1 mRNA expression in prostate cancer cells by the DNA methylation inhibitor
-
Fang X, Liu Z, Fan Y, Zheng C, Nilson S, Egevad L, Ekman P, Xu D. Switch to full-length of XAF1 mRNA expression in prostate cancer cells by the DNA methylation inhibitor. Int J Cancer 2006;118:2485-9.
-
(2006)
Int J Cancer
, vol.118
, pp. 2485-2489
-
-
Fang, X.1
Liu, Z.2
Fan, Y.3
Zheng, C.4
Nilson, S.5
Egevad, L.6
Ekman, P.7
Xu, D.8
-
32
-
-
33747339752
-
Overcoming resistance to interferoninduced apoptosis of renal carcinoma and melanoma cells by DNA demethylation
-
Reu FJ, Bae SI, Cherkassky L, Leaman DW, Lindner D, Beaulieu N, MacLeod AR, Borden EC. Overcoming resistance to interferoninduced apoptosis of renal carcinoma and melanoma cells by DNA demethylation. J Clin Oncol 2006;24:3771-9.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3771-3779
-
-
Reu, F.J.1
Bae, S.I.2
Cherkassky, L.3
Leaman, D.W.4
Lindner, D.5
Beaulieu, N.6
MacLeod, A.R.7
Borden, E.C.8
-
33
-
-
34547258025
-
Gene expression and promoter methylation of the XIAP-associated Factor 1 in renal cell carcinomas: Correlations with pathology and outcome
-
Kempkensteffen C, Hinz S, Schrader M, Christoph F, Magheli A, Krause H, Schostak M, Miller K, Weikert S. Gene expression and promoter methylation of the XIAP-associated Factor 1 in renal cell carcinomas: correlations with pathology and outcome. Cancer Lett 2007;254:227-35.
-
(2007)
Cancer Lett
, vol.254
, pp. 227-235
-
-
Kempkensteffen, C.1
Hinz, S.2
Schrader, M.3
Christoph, F.4
Magheli, A.5
Krause, H.6
Schostak, M.7
Miller, K.8
Weikert, S.9
-
34
-
-
34250001970
-
Frequent alteration of XAF1 in human colorectal cancers: Implication for tumor cell resistance to apoptotic stresses
-
Chung SK, Lee MG, Ryu BK, Lee JH, Han J, Byun DS, Chae KS, Lee KY, Jang JY, Kim HJ, Chi SG. Frequent alteration of XAF1 in human colorectal cancers: implication for tumor cell resistance to apoptotic stresses. Gastroenterology 2007;132:2459-77.
-
(2007)
Gastroenterology
, vol.132
, pp. 2459-2477
-
-
Chung, S.K.1
Lee, M.G.2
Ryu, B.K.3
Lee, J.H.4
Han, J.5
Byun, D.S.6
Chae, K.S.7
Lee, K.Y.8
Jang, J.Y.9
Kim, H.J.10
Chi, S.G.11
-
35
-
-
34047227918
-
Silencing of the XAF1 gene by promoter hypermethylation in cancer cells and reactivation to TRAIL-sensitization by IFN-beta
-
Micali OC, Cheung HH, Plenchette S, Hurley SL, Liston P, LaCasse EC, Korneluk RG. Silencing of the XAF1 gene by promoter hypermethylation in cancer cells and reactivation to TRAIL-sensitization by IFN-beta. BMC Cancer 2007;7:52-8.
-
(2007)
BMC Cancer
, vol.7
, pp. 52-58
-
-
Micali, O.C.1
Cheung, H.H.2
Plenchette, S.3
Hurley, S.L.4
Liston, P.5
LaCasse, E.C.6
Korneluk, R.G.7
-
36
-
-
38149058329
-
Regulation of XAF1 expression in human colon cancer cell by interferon beta: Activation by the transcription regulator STAT1
-
Sun Y, Qiao L, Xia HH, Lin MC, Zou B, Yuan Y, Zhu S, Gu Q, Cheung TK, Kung HF, Yuen MF, Chan AO, et al. Regulation of XAF1 expression in human colon cancer cell by interferon beta: activation by the transcription regulator STAT1. Cancer Lett 2008;260:62-71.
-
(2008)
Cancer Lett
, vol.260
, pp. 62-71
-
-
Sun, Y.1
Qiao, L.2
Xia, H.H.3
Lin, M.C.4
Zou, B.5
Yuan, Y.6
Zhu, S.7
Gu, Q.8
Cheung, T.K.9
Kung, H.F.10
Yuen, M.F.11
Chan, A.O.12
-
37
-
-
34248335752
-
XAF1 mediates apoptosis through an extracellular signal-regulated kinase pathway in colon cancer
-
Yu LF, Wang J, Zou B, Lin MC, Wu YL, Xia HH, Sun YW, Gu Q, He H, Lam SK, Kung HF, Wong BC. XAF1 mediates apoptosis through an extracellular signal-regulated kinase pathway in colon cancer. Cancer 2007;109:1996-2003.
-
(2007)
Cancer
, vol.109
, pp. 1996-2003
-
-
Yu, L.F.1
Wang, J.2
Zou, B.3
Lin, M.C.4
Wu, Y.L.5
Xia, H.H.6
Sun, Y.W.7
Gu, Q.8
He, H.9
Lam, S.K.10
Kung, H.F.11
Wong, B.C.12
|