Suppression of Survivin Expression Inhibits in Vivo Tumorigenicity and Angiogenesis in Gastric Cancer

Cancer Research

Volumn 63, Issue 22, 2003, Pages 7724-7732

  Tu, Shui Ping ^a,b   Jiang, Xiao Hua ^a,b   Lin, Marie C M ^b   Cui, Jian Tao ^b   Yang, Yi ^b   Lum, Ching Tung ^b   Zou, Bing ^a,b   Zhu, Yan Bo ^a   Jiang, Shi Hu ^a   Wong, Wai Man ^b   Chan, Annie On On ^b   Yuen, Man Fung ^b   Lam, Shiu Kum ^b   Kung, Hsiang Fu ^b   Wong, Benjamin Chun Yu ^b  

^a SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMINO ACID; COMPLEMENTARY DNA; CYSTEINE; SURVIVIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CARCINOGENESIS; CARCINOGENICITY; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; MORPHOLOGY; MOUSE; MUTANT; NONHUMAN; NUDE MOUSE; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; STOMACH ADENOCARCINOMA; STOMACH CANCER; STOMACH TUMOR; XERORADIOGRAPHY;

ADENOCARCINOMA; ANIMALS; APOPTOSIS; CELL DIVISION; CELL LINE, TUMOR; DNA, ANTISENSE; FEMALE; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; MICROTUBULE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; NEOVASCULARIZATION, PATHOLOGIC; STOMACH NEOPLASMS; TRANSFECTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 10744232690     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Li, F., Ambrosini, G., Chu, E. Y., Plescia, J., Tognin, S., Marchisio, P. C., and Altieri, D. C. Control of apoptosis and mitotic spindle checkpoint by survivin. Nature (Lond.), 396: 580-584, 1998.
2. Reed, J. C., and Bischoff, J. R. BIRinging chromosomes through cell division: and survivin' the experience. Cell, 102: 545-548, 2000.
3. Giodini, A., Kallio, M. J., Wall, N. R., Gorbsky, G. J., Tognin, S., Marchisio, P. C., Symons, M., and Altieri, D. C. Regulation of microtubule stability and mitotic progression by survivin. Cancer Res., 62: 2462-2467, 2002.
4. Ambrosini, G., Adida, C., and Altieri, D. C. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat. Med., 3: 917-921, 1997.
5. Monzo, M., Rosell, R., Felip, E., Astudillo, J., Sanchezm, J. J., Maestre, J., Martin, C., Font, A., Barnadas, A., and Avad, A. A novel anti-apoptosis gene: re-expression of survivin messenger RNA as a prognosis marker in non-small-cell lung cancers. J. Clin. Oncol., 17: 2100-2104, 1999.
6. Swana, H. S., Grossman, D., Anthony, J. N., Weiss, R. M., and Altieri, D. C. Tumor content of the antiapoptosis molecule survivin and recurrence of bladder cancer. N. Engl. J. Med., 341: 452-453, 1999.
7. Adida, C., Haioun, C., Gaulard, P., Lepage, E., Morel, P., Briere, J., Dombret, H., Reyes, F., Diebold, J., Gisselbrecht, C., Salles, G., Altieri, D. C., and Molina, T. J. Prognostic significance of survivin expression in diffuse large B-cell lymphomas. Blood, 96: 1921-1925, 2000.
8. Kato, J., Kuwabara, Y., Mitani, M., Shinoda, N., Sato, A., Toyama, T., Mitsui, A., Nishiwaki, T., Moriyama, S., Kudo, J., and Fujii, Y. Expression of survivin in esophageal cancer: correlation with the prognosis and response to chemotherapy. Int. J. Cancer, 95: 92-95, 2001.
9. O'Connor, D. S., Grossman, D., Plescia, J., Li, F., Zhang, H., Villa, A., Tognin, S., Marchisio, P. C., and Altieri, D. C. Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin. Proc. Natl. Acad. Sci. USA, 97: 13103-13107, 2000.
10. Chen, J., Wu, W., Tahir, S. K., Kroeger, P. E., Rosenberg, S. H., Cowsert, L. M., Bennett, F., Krajewski, S., Krajewska, M., Welsh, K., Reed, J. C., and Ng, S. C. Down-regulation of survivin by antisense oligonucleotides increases apoptosis, inhibits cytokinesis and anchorage-independent growth. Neoplasia, 2: 235-241, 2000.
11. Li, F., Ackermann, E. J., Bennett, C. F., Rothetmel, A. L., Plescia, J., Tognin, S., Villa, A., Marchisio, P. C., and Altieri, D. C. Pleiotropic cell-division defects and apoptosis induced by interference with survivin function. Nat. Cell Biol., 1: 461-466, 1999.
12. Olie, R. A., Simoes-Wust, A. P., Baumann, B., Leech, S. H., Fabbro, D., Stahel, R. A., and Zangemeister-Wittke, U. A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy. Cancer Res., 60: 2805-2809, 2000.
13. Roninson, I. B., Broude, E. V., and Chang, B. D. If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells. Drug Resist. Updat., 4: 303-313, 2001.
14. Grossman, D., Kim, P. J., Schechner, J. S., and Altieri, D. C. Inhibition of melanoma tumor growth in vivo by survivin targeting. Proc. Natl. Acad. Sci. USA, 98: 635-640, 2001.
15. Mesri, M., Wall, N. R., Li, J., Kim, R. W., and Altieri, D. C. Cancer gene therapy using a survivin mutant adenovirus. J. Clin. Investig., 108: 981-990, 2001.
16. 34 by flavopiridol enhances tumor cell apoptosis. Cancer Res., 63: 230-235, 2003.
17. Kanwar, J. R., Shen, W. P., Kanwar, R. K., Berg, R. W., and Krissansen, G. W. Effects of survivin antagonists on growth of established tumors and b7-1 immunogene therapy. J. Natl. Cancer. Inst. (Bethesda), 93: 1541-1552, 2001.
18. Altieri, D. C. Validating survivin as a cancer therapeutic target. Nat. Rev. Cancer, 3: 46-54, 2003.
19. O'Connor, D. S., Daniel, S., Jeffrey, S., Schechner, S., Adida, C., Mesri, M., Rothermel, A. L., Li, F. Z., Nath, A. K., Pober, J. S., and Altieri, D. C. Control of apoptosis during angiogenesis by survivin expression in endothelial cells. Am. J. Pathol., 156: 393-398, 2000.
20. Tran, J., Rak, J., Sheehan, C., Saibil, S. D., LaCasse, E., Korneluk, R. G., and Kerbel, R. S. Marked induction of the IAP family antiapoptotic proteins survivin and XIAP by VEGF in vascular endothelial cells. Biochem. Biophys. Res. Commun, 264: 781-788, 1999.
21. Papapetropoulos, A., Fulton, D., Mahboubi, K., Kalb, R. G., O'Connor, D. S., Li, F., Altieri, D. C., and Sessa, W. C. Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway. J. Biol. Chem., 275: 9102-9105, 2000.
22. Lu, C. D., Altieri, D. C., and Tanigawa, N. Expression of a novel antiapoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas. Cancer Res., 58: 1808-1812, 1998.
23. Okada, E., Mural, Y., Matsui, K., Isizawa, S., Cheng, C., Masuda, M., and Takano, Y. Survivin expression in tumor cell nuclei is predictive of a favorable prognosis in gastric cancer patients. Cancer Lett., 163: 109-116, 2001.
24. Krieg, A., Mahotka, C., Krieg, T., Grabsch, H., Muller, W., Takeno, S., Suschek, C. V., Heydthausen, M., Gabbert, H. E., and Gerharz, C. D. Expression of different survivin variants in gastric carcinomas: first clues to a role of survivin-2B in tumour progression. Br. J. Cancer, 86: 737-743, 2002.
25. Ikeguchi, M., Liu, J., and Kaibara, N. Expression of survivin mRNA and protein in gastric cancer cell line (MKN-45) during cisplatin treatment. Apoptosis, 7: 23-29, 2002.
26. Li, Q. F., Ou-Yang, G. L., Li, C. Y., and Hong, S. G. Effects of tachyplesin on the morphology and ultrastructure of human gastric carcinoma cell line BGC-823. World J. Gastroenterol., 6: 676-680, 2000.
27. Chen, C., Liu, F-K., Qi, X-P., and Li, J-S. The study of chemiluminescence in gastric and colonic carcinoma cell lines treated by anti-tumor drugs. World J. Gastroenterol., 9: 242-245. 2003.
28. Ji, J. F., Chen, X., Leung, S. Y., Chi, J-T. A., Chu, K. M., Yuen, S. T., Li, R., Chan, A. S. Y., Li, J. Y., Dunphy, N., and So, S. Comprehensive analysis of the gene expression profiles in human gastric cancer cell lines. Oncogene, 21: 6549-6556, 2002.
29. Yokozaki, H. Molecular characteristics of eight gastric cancer cell lines established in Japan. Pathol. Int., 50: 767-777, 2000.
30. Giatromanolaki, A., Koukourakis, M. I., Theodossiou, D., Barbatis, K., O'Byrne, K., Harris, A. L., and Gatter, K. C. Comparative evaluation of angiogenesis assessment with anti-factor-VIII and anti-CD31 immunostaining in non-small cell lung cancer. Clin. Cancer Res., 3: 2485-2492, 1997.
31. Shah, M. A. Recent developments in the treatment of gastric carcinoma. Curr. Oncol. Rep., 4: 193-201, 2002.
32. Temme, A., Rieger, M., Reber, F., Lindemann, D., Weigle, B., Diestelkoetter-Bachert, P., Ehninger, G., Tatsuka, M., Terada, Y., and Rieber, E. P. Localization, dynamics, and function of survivin revealed by expression of functional survivinD-sRed fusion proteins in the living cell. Mol. Biol. Cell, 14: 78-92, 2003.
33. Canman, C. E. Replication checkpoint: preventing mitotic catastrophe. Curr. Biol., 11: R121-R124, 2001.
34. Hanahan, D., and Folkman, J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis (review). Cell, 86: 353-364, 1996.
35. Fidler, I. J., and Ellis, L. M. The implications of angiogenesis for the biology and therapy of cancer metastasis (minireview). Cell, 79: 185-188, 1994.
36. Maeda, K., Chung, Y. S., and Ogawa, Y. Prognostic value of vascular endothelial growth factor expression in gastric carcinoma. Cancer (Phila.), 77: 858-863, 1996.
37. Takahashi, Y., Cleary, K. R., Mai, M., Kitadai, Y., Bucana, C. D., and Ellis, L. M. Significance of vessel count and vascular endothelial growth factor and its receptor (KDR) in intestinal-type gastric cancer. Clin. Cancer Res., 2: 1679-1684, 1996.
38. Mesri, M., Morales-Ruiz, M., Ackermann, E. J., Bennett, C. F., Pober, J. S., Sessa, W. C., and Altieri, D. C. Suppression of vascular endothelial growth factor-mediated endothelial cell protection by survivin targeting. Am. J. Pathol., 158: 1757-1765, 2001.
39. Tran, J., Master, Z. B., Yu, J. L., Rak, J., Dumont, D. J., and Kerbel, R. S. A role for survivin in chemoresistance of endothelial cells mediated by VEGF. Proc. Natl. Acad. Sci. USA, 99: 4349-4354, 2002.