-
1
-
-
26444470888
-
Reawakening the cellular death program in neoplasia through the therapeutic blockade of IAP function
-
1236691 16200201 10.1172/JCI26251
-
Wright CW Duckett CS Reawakening the cellular death program in neoplasia through the therapeutic blockade of IAP function J Clin Invest 2005 115 2673-2678 1236691 16200201 10.1172/JCI26251
-
(2005)
J Clin Invest
, vol.115
, pp. 2673-2678
-
-
Wright, C.W.1
Duckett, C.S.2
-
2
-
-
0034607655
-
Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli
-
10.1126/science.288.5467.874 10797013 10797013
-
Yang Y Fang S Jensen JP Weissman AM Ashwell JD Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli Science 2000 288 874-877 10.1126/science.288.5467.874 10797013
-
(2000)
Science
, vol.288
, pp. 874-877
-
-
Yang, Y.1
Fang, S.2
Jensen, J.P.3
Weissman, A.M.4
Ashwell, J.D.5
-
3
-
-
0346880501
-
The inhibitors of apoptosis: There is more to life than Bcl2
-
10.1038/sj.onc.1207101 14634619
-
Liston P Fong WG Korneluk RG The inhibitors of apoptosis: There is more to life than Bcl2 Oncogene 2003 22 8568-8580 10.1038/sj.onc.1207101 14634619
-
(2003)
Oncogene
, vol.22
, pp. 8568-8580
-
-
Liston, P.1
Fong, W.G.2
Korneluk, R.G.3
-
4
-
-
0035156848
-
Identification of XAF1 as an antagonist of XIAP anti-Caspase activity
-
10.1038/35055027 11175744
-
Liston P Fong WG Kelly NL Toji S Miyazaki T Conte D Tamai K Craig CG McBurney MW Korneluk RG Identification of XAF1 as an antagonist of XIAP anti-Caspase activity Nat Cell Biol 2001 3 128-133 10.1038/35055027 11175744
-
(2001)
Nat Cell Biol
, vol.3
, pp. 128-133
-
-
Liston, P.1
Fong, W.G.2
Kelly, N.L.3
Toji, S.4
Miyazaki, T.5
Conte, D.6
Tamai, K.7
Craig, C.G.8
McBurney, M.W.9
Korneluk, R.G.10
-
5
-
-
9744232952
-
XAF1 expression is significantly reduced in human melanoma
-
10.1111/j.0022-202X.2004.23467.x 15610524
-
Ng KC Campos EI Martinka M Li G XAF1 expression is significantly reduced in human melanoma J Invest Dermatol 2004 123 1127-1134 10.1111/ j.0022-202X.2004.23467.x 15610524
-
(2004)
J Invest Dermatol
, vol.123
, pp. 1127-1134
-
-
Ng, K.C.1
Campos, E.I.2
Martinka, M.3
Li, G.4
-
6
-
-
33748922416
-
Promoter CpG hypermethylation and downregulation of XAF1 expression in human urogenital malignancies: Implication for attenuated p53 response to apoptotic stresses
-
10.1038/sj.onc.1209867 16909101
-
Lee MG Huh JS Chung SK Lee JH Byun DS Ryu BK Kang MJ Chae KS Lee SJ Lee CH Kim JI Chang SG Chi SG Promoter CpG hypermethylation and downregulation of XAF1 expression in human urogenital malignancies: implication for attenuated p53 response to apoptotic stresses Oncogene 2006 25 5807-5822 10.1038/sj.onc.1209867 16909101
-
(2006)
Oncogene
, vol.25
, pp. 5807-5822
-
-
Lee, M.G.1
Huh, J.S.2
Chung, S.K.3
Lee, J.H.4
Byun, D.S.5
Ryu, B.K.6
Kang, M.J.7
Chae, K.S.8
Lee, S.J.9
Lee, C.H.10
Kim, J.I.11
Chang, S.G.12
Chi, S.G.13
-
7
-
-
0037047285
-
Identification of X-linked inhibitor of apoptosis-associated factor-1 as an interferon-stimulated gene that augments TRAIL Apo2L-induced apoptosis
-
10.1074/jbc.M204851200 12029096
-
Leaman DW Chawla-Sarkar M Vyas K Reheman M Tamai K Toji S Borden EC Identification of X-linked inhibitor of apoptosis-associated factor-1 as an interferon-stimulated gene that augments TRAIL Apo2L-induced apoptosis J Biol Chem 2002 277 28504-28511 10.1074/jbc.M204851200 12029096
-
(2002)
J Biol Chem
, vol.277
, pp. 28504-28511
-
-
Leaman, D.W.1
Chawla-Sarkar, M.2
Vyas, K.3
Reheman, M.4
Tamai, K.5
Toji, S.6
Borden, E.C.7
-
8
-
-
33646252040
-
Xaf1 can cooperate with TNFalpha in the induction of apoptosis, independently of interaction with XIAP
-
10.1007/s11010-005-9094-2 16432762
-
Xia Y Novak R Lewis J Duckett CS Phillips AC Xaf1 can cooperate with TNFalpha in the induction of apoptosis, independently of interaction with XIAP Mol Cell Biochem 2006 286 67-76 10.1007/s11010-005-9094-2 16432762
-
(2006)
Mol Cell Biochem
, vol.286
, pp. 67-76
-
-
Xia, Y.1
Novak, R.2
Lewis, J.3
Duckett, C.S.4
Phillips, A.C.5
-
9
-
-
0034672506
-
Expression and genetic analysis of XIAP-associated factor 1 (XAF1) in cancer cell lines
-
10.1006/geno.2000.6364 11087668
-
Fong WG Liston P Rajcan-Separovic E St Jean M Craig C Korneluk RG Expression and genetic analysis of XIAP-associated factor 1 (XAF1) in cancer cell lines Genomics 2000 70 113-122 10.1006/geno.2000.6364 11087668
-
(2000)
Genomics
, vol.70
, pp. 113-122
-
-
Fong, W.G.1
Liston, P.2
Rajcan-Separovic, E.3
St Jean, M.4
Craig, C.5
Korneluk, R.G.6
-
10
-
-
0242442595
-
Hypermethylation of XIAP-associated factor 1, a putative tumor suppressor gene from the 17p13.2 locus, in human gastric adenocarcinomas
-
14612497
-
Byun DS Cho K Ryu BK Lee MG Kang MJ Kim HR Chi SG Hypermethylation of XIAP-associated factor 1, a putative tumor suppressor gene from the 17p13.2 locus, in human gastric adenocarcinomas Cancer Res 2003 63 7068-7075 14612497
-
(2003)
Cancer Res
, vol.63
, pp. 7068-7075
-
-
Byun, D.S.1
Cho, K.2
Ryu, B.K.3
Lee, M.G.4
Kang, M.J.5
Kim, H.R.6
Chi, S.G.7
-
11
-
-
0037068358
-
Reactivating the expression of methylation silenced genes in human cancer
-
10.1038/sj.onc.1205602 12154410
-
Karpf AR Jones DA Reactivating the expression of methylation silenced genes in human cancer Oncogene 2002 21 5496-5503 10.1038/sj.onc.1205602 12154410
-
(2002)
Oncogene
, vol.21
, pp. 5496-5503
-
-
Karpf, A.R.1
Jones, D.A.2
-
12
-
-
0038677615
-
Epigenetic silencing of multiple interferon pathway genes after cellular immortalization
-
10.1038/sj.onc.1206594 12821946
-
Kulaeva OI Draghici S Tang L Kraniak JM Land SJ Tainsky MA Epigenetic silencing of multiple interferon pathway genes after cellular immortalization Oncogene 2003 22 4118-4127 10.1038/sj.onc.1206594 12821946
-
(2003)
Oncogene
, vol.22
, pp. 4118-4127
-
-
Kulaeva, O.I.1
Draghici, S.2
Tang, L.3
Kraniak, J.M.4
Land, S.J.5
Tainsky, M.A.6
-
13
-
-
0034046395
-
Inhibition of the interferon-gamma/signal transducers and activators of transcription (STAT) pathway by hypermethylation at a STAT-binding site in the p21WAF1 promoter region
-
10866323
-
Chen B He L Savell VH Jenkins JJ Parham DM Inhibition of the interferon-gamma/signal transducers and activators of transcription (STAT) pathway by hypermethylation at a STAT-binding site in the p21WAF1 promoter region Cancer Res 2000 60 3290-3298 10866323
-
(2000)
Cancer Res
, vol.60
, pp. 3290-3298
-
-
Chen, B.1
He, L.2
Savell, V.H.3
Jenkins, J.J.4
Parham, D.M.5
-
14
-
-
0037621450
-
Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation
-
10.1038/sj.cdd.4401157 12700635
-
Hopkins-Donaldson S Ziegler A Kurtz S Bigosch C Kandioler D Ludwig C Zangemeister-Wittke U Stahel R Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation Cell Death Differ 2003 10 356-364 10.1038/sj.cdd.4401157 12700635
-
(2003)
Cell Death Differ
, vol.10
, pp. 356-364
-
-
Hopkins-Donaldson, S.1
Ziegler, A.2
Kurtz, S.3
Bigosch, C.4
Kandioler, D.5
Ludwig, C.6
Zangemeister-Wittke, U.7
Stahel, R.8
-
15
-
-
8544250516
-
Interferon-gamma induces caspase-8 in neuroblastomas without affecting methylation of caspase-8 promoter
-
10.1016/j.jpedsurg.2003.12.009 15065018
-
Kim S Kang J Evers BM Chung DH Interferon-gamma induces caspase-8 in neuroblastomas without affecting methylation of caspase-8 promoter J Pediatr Surg 2004 39 509-515 10.1016/j.jpedsurg.2003.12.009 15065018
-
(2004)
J Pediatr Surg
, vol.39
, pp. 509-515
-
-
Kim, S.1
Kang, J.2
Evers, B.M.3
Chung, D.H.4
-
16
-
-
20144367828
-
Caspase-8 gene expression in neuroblastoma
-
10.1196/annals.1322.017 15650242
-
Casciano I Banelli B Croce M De Ambrosis A di Vinci A Gelvi I Pagnan G Brignole C Allemanni G Ferrini S Ponzoni M Romani M Caspase-8 gene expression in neuroblastoma Ann N Y Acad Sci 2004 1028 157-167 10.1196/ annals.1322.017 15650242
-
(2004)
Ann N Y Acad Sci
, vol.1028
, pp. 157-167
-
-
Casciano, I.1
Banelli, B.2
Croce, M.3
De Ambrosis, A.4
di Vinci, A.5
Gelvi, I.6
Pagnan, G.7
Brignole, C.8
Allemanni, G.9
Ferrini, S.10
Ponzoni, M.11
Romani, M.12
-
17
-
-
0037089589
-
Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
-
152352 11959843 10.1101/gad.981002
-
Paddison PJ Caudy AA Bernstein E Hannon GJ Conklin DS Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells Genes Dev 2002 16 948-958 152352 11959843 10.1101/gad.981002
-
(2002)
Genes Dev
, vol.16
, pp. 948-958
-
-
Paddison, P.J.1
Caudy, A.A.2
Bernstein, E.3
Hannon, G.J.4
Conklin, D.S.5
-
18
-
-
7944229824
-
Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics
-
10.1038/sj.onc.1207967 15378029
-
McManus DC Lefebvre CA Cherton-Horvat G St-Jean M Kandimalla ER Agrawal S Morris SJ Durkin JP Lacasse EC Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics Oncogene 2004 23 8105-8117 10.1038/sj.onc.1207967 15378029
-
(2004)
Oncogene
, vol.23
, pp. 8105-8117
-
-
McManus, D.C.1
Lefebvre, C.A.2
Cherton-Horvat, G.3
St-Jean, M.4
Kandimalla, E.R.5
Agrawal, S.6
Morris, S.J.7
Durkin, J.P.8
Lacasse, E.C.9
-
20
-
-
0345357773
-
Gene silencing in cancer in association with promoter hypermethylation
-
10.1056/NEJMra023075 14627790
-
Herman JG Baylin SB Gene silencing in cancer in association with promoter hypermethylation N Engl J Med 2003 349 2042-2054 10.1056/ NEJMra023075 14627790
-
(2003)
N Engl J Med
, vol.349
, pp. 2042-2054
-
-
Herman, J.G.1
Baylin, S.B.2
-
21
-
-
33747339752
-
Overcoming resistance to interferon-induced apoptosis of renal carcinoma and melanoma cells by DNA demethylation
-
10.1200/JCO.2005.03.4074 16801630
-
Reu FJ Bae SI Cherkassky L Leaman DW Lindner D Beaulieu N MacLeod AR Borden EC Overcoming resistance to interferon-induced apoptosis of renal carcinoma and melanoma cells by DNA demethylation J Clin Oncol 2006 24 3771-3779 10.1200/JCO.2005.03.4074 16801630
-
(2006)
J Clin Oncol
, vol.24
, pp. 3771-3779
-
-
Reu, F.J.1
Bae, S.I.2
Cherkassky, L.3
Leaman, D.W.4
Lindner, D.5
Beaulieu, N.6
MacLeod, A.R.7
Borden, E.C.8
-
22
-
-
33845645132
-
Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers
-
10.1053/j.gastro.2006.09.050 17087954
-
Zou B Chim CS Zeng H Leung SY Yang Y Tu SP Lin MC Wang J He H Jiang SH Sun YW Yu LF Yuen ST Kung HF Wong BC Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers Gastroenterology 2006 131 1835-1843 10.1053/ j.gastro.2006.09.050 17087954
-
(2006)
Gastroenterology
, vol.131
, pp. 1835-1843
-
-
Zou, B.1
Chim, C.S.2
Zeng, H.3
Leung, S.Y.4
Yang, Y.5
Tu, S.P.6
Lin, M.C.7
Wang, J.8
He, H.9
Jiang, S.H.10
Sun, Y.W.11
Yu, L.F.12
Yuen, S.T.13
Kung, H.F.14
Wong, B.C.15
-
24
-
-
0035061538
-
IRF family of transcription factors as regulators of host defense
-
10.1146/annurev.immunol.19.1.623 11244049
-
Taniguchi T Ogasawara K Takaoka A Tanaka N IRF family of transcription factors as regulators of host defense Annu Rev Immunol 2001 19 623-655 10.1146/annurev.immunol.19.1.623 11244049
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 623-655
-
-
Taniguchi, T.1
Ogasawara, K.2
Takaoka, A.3
Tanaka, N.4
-
25
-
-
16244409253
-
Interferons as pathogenic effectors in autoimmunity
-
10.1111/j.0105-2896.2005.00252.x 15790347
-
Baccala R Kono DH Theofilopoulos AN Interferons as pathogenic effectors in autoimmunity Immunol Rev 2005 204 9-26 10.1111/ j.0105-2896.2005.00252.x 15790347
-
(2005)
Immunol Rev
, vol.204
, pp. 9-26
-
-
Baccala, R.1
Kono, D.H.2
Theofilopoulos, A.N.3
-
26
-
-
34047226445
-
Hyper-activated IRF-1 and STAT1 contribute to enhanced Interferon stimulated gene (ISG) expression by Interferon alpha and gamma co-treatment in human hepatoma cells
-
16987558
-
Zhang XN Liu JX Hu YW Chen H Yuan ZH Hyper-activated IRF-1 and STAT1 contribute to enhanced Interferon stimulated gene (ISG) expression by Interferon alpha and gamma co-treatment in human hepatoma cells Biochim Biophys Acta 2006 1759 417-425 16987558
-
(2006)
Biochim Biophys Acta
, vol.1759
, pp. 417-425
-
-
Zhang, X.N.1
Liu, J.X.2
Hu, Y.W.3
Chen, H.4
Yuan, Z.H.5
-
27
-
-
18344390653
-
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
-
10.1038/416552a 11932749
-
Rhee I Bachman KE Park BH Jair KW Yen RW Schuebel KE Cui H Feinberg AP Lengauer C Kinzler KW Baylin SB Vogelstein B DNMT1 and DNMT3b cooperate to silence genes in human cancer cells Nature 2002 416 552-556 10.1038/ 416552a 11932749
-
(2002)
Nature
, vol.416
, pp. 552-556
-
-
Rhee, I.1
Bachman, K.E.2
Park, B.H.3
Jair, K.W.4
Yen, R.W.5
Schuebel, K.E.6
Cui, H.7
Feinberg, A.P.8
Lengauer, C.9
Kinzler, K.W.10
Baylin, S.B.11
Vogelstein, B.12
-
28
-
-
33646349241
-
HSF1 down-regulates XAF1 through transcriptional regulation
-
10.1074/jbc.M505890200 16303760 16303760
-
Wang J He H Yu L Xia HH Lin MC Gu Q Li M Zou B An X Jiang B Kung HF Wong BC HSF1 down-regulates XAF1 through transcriptional regulation J Biol Chem 2006 281 2451-2459 10.1074/jbc.M505890200 16303760
-
(2006)
J Biol Chem
, vol.281
, pp. 2451-2459
-
-
Wang, J.1
He, H.2
Yu, L.3
Xia, H.H.4
Lin, M.C.5
Gu, Q.6
Li, M.7
Zou, B.8
An, X.9
Jiang, B.10
Kung, H.F.11
Wong, B.C.12
-
29
-
-
33644868920
-
All-trans retinoic acid induces XAF1 expression through an interferon regulatory factor-1 element in colon cancer
-
10.1053/j.gastro.2005.12.017 16530516
-
Wang J Peng Y Sun YW He H Zhu S An X Li M Lin MC Zou B Xia HH Jiang B Chan AO Yuen MF Kung HF Wong BC All-trans retinoic acid induces XAF1 expression through an interferon regulatory factor-1 element in colon cancer Gastroenterology 2006 130 747-758 10.1053/j.gastro.2005.12.017 16530516
-
(2006)
Gastroenterology
, vol.130
, pp. 747-758
-
-
Wang, J.1
Peng, Y.2
Sun, Y.W.3
He, H.4
Zhu, S.5
An, X.6
Li, M.7
Lin, M.C.8
Zou, B.9
Xia, H.H.10
Jiang, B.11
Chan, A.O.12
Yuen, M.F.13
Kung, H.F.14
Wong, B.C.15
-
30
-
-
0031928180
-
Interferon and malignant disease - How does it work and why doesn't it always?
-
10.1080/028418698430548 9743454
-
Grander D Einhorn S Interferon and malignant disease - how does it work and why doesn't it always? Acta Oncol 1998 37 331-338 10.1080/ 028418698430548 9743454
-
(1998)
Acta Oncol
, vol.37
, pp. 331-338
-
-
Grander, D.1
Einhorn, S.2
-
32
-
-
11044230488
-
Interferon-beta gene therapy for cancer: Basic research to clinical application
-
10.1111/j.1349-7006.2004.tb02194.x 15546502
-
Yoshida J Mizuno M Wakabayashi T Interferon-beta gene therapy for cancer: Basic research to clinical application Cancer Sci 2004 95 858-865 10.1111/j.1349-7006.2004.tb02194.x 15546502
-
(2004)
Cancer Sci
, vol.95
, pp. 858-865
-
-
Yoshida, J.1
Mizuno, M.2
Wakabayashi, T.3
-
33
-
-
14844288360
-
Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: Paving the road to patient-tailored therapy
-
10.1016/j.drup.2004.11.002 15790545
-
Van Geelen CM de Vries EG de Jong S Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: Paving the road to patient-tailored therapy Drug Resist Updat 2004 7 345-358 10.1016/ j.drup.2004.11.002 15790545
-
(2004)
Drug Resist Updat
, vol.7
, pp. 345-358
-
-
Van Geelen, C.M.1
de Vries, E.G.2
de Jong, S.3
-
35
-
-
0038444699
-
Targeting the tumor necrosis factor-related apoptosis-inducing ligand path in neuroblastoma
-
10.1016/S0304-3835(03)00093-4 12880973
-
Yang X Thiele CJ Targeting the tumor necrosis factor-related apoptosis-inducing ligand path in neuroblastoma Cancer Lett 2003 197 137-143 10.1016/S0304-3835(03)00093-4 12880973
-
(2003)
Cancer Lett
, vol.197
, pp. 137-143
-
-
Yang, X.1
Thiele, C.J.2
|