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Volumn 16, Issue 4, 2009, Pages 823-831

Growth factors, AGEing, and the diabetes link in Alzheimer's disease

Author keywords

Advanced glycation end products; Alzheimer's disease; Diabetes mellitus; Growth factors

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; CELL RECEPTOR; CONNECTIVE TISSUE GROWTH FACTOR; GROWTH FACTOR; INSULIN; NERVE GROWTH FACTOR; NEUROTROPHIC FACTOR; RECOMBINANT PLATELET DERIVED GROWTH FACTOR; SOMATOMEDIN C; VASCULOTROPIN; SIGNAL PEPTIDE;

EID: 67649726060     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2009-0997     Document Type: Review
Times cited : (6)

References (82)
  • 1
    • 0020534018 scopus 로고
    • Changes in blood glucose and insulin secretion in patients with senile dementia of Alzheimer type
    • Bucht H, Adolfsson R, Lithner K, Winblad B (1983) Changes in blood glucose and insulin secretion in patients with senile dementia of Alzheimer type. Acta Med Scand 213, 387-392.
    • (1983) Acta Med Scand , vol.213 , pp. 387-392
    • Bucht, H.1    Adolfsson, R.2    Lithner, K.3    Winblad, B.4
  • 3
    • 29044449855 scopus 로고    scopus 로고
    • Risk of dementia in diabetes mellitus: A systematic review
    • DOI 10.1016/S1474-4422(05)70284-2, PII S1474442205702842
    • Biessels GJ, Staekenborg S, Brunner E, Brayne C, Scheltens P (2006) Risk of dementia in diabetes mellitus: a systematic review. Lancet Neurol 5, 64-74. (Pubitemid 41790697)
    • (2006) Lancet Neurology , vol.5 , Issue.1 , pp. 64-74
    • Biessels, G.J.1    Staekenborg, S.2    Brunner, E.3    Brayne, C.4    Scheltens, P.5
  • 6
    • 23844522541 scopus 로고    scopus 로고
    • Aggregation of vascular risk factors and risk of incident Alzheimer disease
    • DOI 10.1212/01.wnl.0000172914.08967.dc
    • Luchsinger JA, Reitz C, Honig LS, Tang MX, Shea S, Mayeux R (2005) Aggregation of vascular risk factors and risk of incident Alzheimer disease. Neurology 65, 545-551. (Pubitemid 41170713)
    • (2005) Neurology , vol.65 , Issue.4 , pp. 545-551
    • Luchsinger, J.A.1    Reitz, C.2    Honig, L.S.3    Tang, M.-X.4    Shea, S.5    Mayeux, R.6
  • 8
    • 0036227542 scopus 로고    scopus 로고
    • Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study
    • Peila R, Rodriguez BL, Launer LJ (2002) Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study. Diabetes 51, 1256-1262. (Pubitemid 34438377)
    • (2002) Diabetes , vol.51 , Issue.4 , pp. 1256-1262
    • Peila, R.1    Rodriguez, B.L.2    Launer, L.J.3
  • 9
    • 38349059065 scopus 로고    scopus 로고
    • Enhanced risk for Alzheimer disease in persons with type 2 diabetes and APOE epsilon4: The Cardiovascular Health Study Cognition Study
    • Irie F, Fitzpatrick AL, Lopez OL, Kuller LH, Peila R, Newman AB, Launer LJ (2008) Enhanced risk for Alzheimer disease in persons with type 2 diabetes and APOE epsilon4: the Cardiovascular Health Study Cognition Study. Arch Neurol 65, 89-93.
    • (2008) Arch Neurol , vol.65 , pp. 89-93
    • Irie, F.1    Fitzpatrick, A.L.2    Lopez, O.L.3    Kuller, L.H.4    Peila, R.5    Newman, A.B.6    Launer, L.J.7
  • 10
    • 0029012763 scopus 로고
    • Incidence and risk factors of vascular dementia and Alzheimer's disease in a defined elderly Japanese population: The Hisayama Study
    • Yoshitake T, Kiyohara Y, Kato I, Ohmura T, Iwamoto H, Nakayama K, Ohmori S, Nomiyama K, Kawano H, Ueda K, et al. (1995) Incidence and risk factors of vascular dementia and Alzheimer's disease in a defined elderly Japanese population: the Hisayama Study. Neurology 45, 1161-1168.
    • (1995) Neurology , vol.45 , pp. 1161-1168
    • Yoshitake, T.1    Kiyohara, Y.2    Kato, I.3    Ohmura, T.4    Iwamoto, H.5    Nakayama, K.6    Ohmori, S.7    Nomiyama, K.8    Kawano, H.9    Ueda, K.10
  • 12
    • 0036973393 scopus 로고    scopus 로고
    • Diabetes mellitus and the risk of dementia, Alzheimer's disease and vascular cognitive impairment in the Canadian Study of Health and Aging
    • DOI 10.1159/000064928
    • MacKnight C, Rockwood K, Awalt E, McDowell I (2002) Diabetes mellitus and the risk of dementia, Alzheimer's disease and vascular cognitive impairment in the Canadian Study of Health and Aging. Dement Geriatr Cogn Disord 14, 77-83. (Pubitemid 36152948)
    • (2002) Dementia and Geriatric Cognitive Disorders , vol.14 , Issue.2 , pp. 77-83
    • MacKnight, C.1    Rockwood, K.2    Awalt, E.3    McDowell, I.4
  • 13
    • 5344237420 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of dementia in the Kungsholmen project: A 6-year follow-up study
    • Xu WL, Qiu CX, Wahlin A, Winblad B, Fratiglioni L (2004) Diabetes mellitus and risk of dementia in the Kungsholmen project: a 6-year follow-up study. Neurology 63, 1181-1186. (Pubitemid 39350014)
    • (2004) Neurology , vol.63 , Issue.7 , pp. 1181-1186
    • Xu, W.L.1    Qiu, C.X.2    Wahlin, A.3    Winblad, B.4    Fratiglioni, L.5
  • 14
    • 0036759508 scopus 로고    scopus 로고
    • Diabetes mellitus is a risk factor for vascular dementia, but not for Alzheimer's disease: A population-based study of the oldest old
    • DOI 10.1017/S104161020200844X
    • Hassing LB, Johansson B, Nilsson SE, Berg S, Pedersen NL, Gatz M, McClearn G (2002) Diabetes mellitus is a risk factor for vascular dementia, but not for Alzheimer's disease: a population-based study of the oldest old. Int Psychogeriatr 14, 239-248. (Pubitemid 35375539)
    • (2002) International Psychogeriatrics , vol.14 , Issue.3 , pp. 239-248
    • Hassing, L.B.1    Johansson, B.2    Nilsson, S.E.3    Berg, S.4    Pedersen, N.L.5    Gatz, M.6    McClearn, G.7
  • 17
    • 33845704496 scopus 로고    scopus 로고
    • Diabetes is related to cerebral infarction but not to AD pathology in older persons
    • DOI 10.1212/01.wnl.0000247053.45483.4e, PII 0000611420061212000014
    • Arvanitakis Z, Schneider JA, Wilson RS, Li Y, Arnold SE, Wang Z, Bennett DA (2006) Diabetes is related to cerebral infarction but not to AD pathology in older persons. Neurology 67, 1960-1965. (Pubitemid 44967371)
    • (2006) Neurology , vol.67 , Issue.11 , pp. 1960-1965
    • Arvanitakis, Z.1    Schneider, J.A.2    Wilson, R.S.3    Li, Y.4    Arnold, S.E.5    Wang, Z.6    Bennett, D.A.7
  • 20
    • 0031734833 scopus 로고    scopus 로고
    • Efficacy and safety of a topical gel formulation of recombinant human platelet-derived growth factor BB (becaplermin) in patients with chronic neuropathic ulcers. A phase III randomized placebo-controlled double blind study
    • Wieman TJ, Smiell JM, Su Y (1998) Efficacy and safety of a topical gel formulation of recombinant human platelet-derived growth factor BB (becaplermin) in patients with chronic neuropathic ulcers. A phase III randomized placebo-controlled double blind study. Diabetes Care 21, 822-827.
    • (1998) Diabetes Care , vol.21 , pp. 822-827
    • Wieman, T.J.1    Smiell, J.M.2    Su, Y.3
  • 21
    • 49349103253 scopus 로고    scopus 로고
    • Intravitreous anti-VEGF for diabetic retinopathy: Hopes and fears for a new therapeutic strategy
    • Simo R, Hernandez C (2008) Intravitreous anti-VEGF for diabetic retinopathy: hopes and fears for a new therapeutic strategy. Diabetologia 51, 1574-1580.
    • (2008) Diabetologia , vol.51 , pp. 1574-1580
    • Simo, R.1    Hernandez, C.2
  • 22
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • DOI 10.1126/science.1072994
    • Hardy J, Selkoe DJ (2002) The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297, 353-356. (Pubitemid 34790756)
    • (2002) Science , vol.297 , Issue.5580 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 23
    • 0031907459 scopus 로고    scopus 로고
    • Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: Relationship to severity of dementia and apolipoprotein e genotype
    • Craft S, Peskind E, Schwartz MW, Schellenberg GD, Raskind M, Porte Jr. D (1998) Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype. Neurology 50, 164-168. (Pubitemid 28106036)
    • (1998) Neurology , vol.50 , Issue.1 , pp. 164-168
    • Craft, S.1    Peskind, E.2    Schwartz, M.W.3    Schellenberg, G.D.4    Raskind, M.5    Porte Jr., D.6
  • 26
    • 1842633868 scopus 로고    scopus 로고
    • The role of insulin and insulin-like growth factor I in the molecular and cellular mechanisms underlying the pathology of Alzheimer's disease
    • DOI 10.1016/j.ejphar.2004.02.050, PII S0014299904002079
    • Carro E, Torres-Aleman I (2004) The role of insulin and insulin-like growth factor I in the molecular and cellular mechanisms underlying the pathology of Alzheimer's disease. Eur J Pharmacol 490, 127-133. (Pubitemid 38482166)
    • (2004) European Journal of Pharmacology , vol.490 , Issue.1-3 , pp. 127-133
    • Carro, E.1    Torres-Aleman, I.2
  • 27
    • 0035871641 scopus 로고    scopus 로고
    • Stimulation of β-amyloid precursor protein trafficking by insulin reduces intraneuronal β-amyloid and requires mitogen-activated protein kinase signaling
    • Gasparini L, Gouras GK, Wang R, Gross RS, Beal MF, Greengard P, Xu H (2001) Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signalling. J Neurosci 21 (2001), 2561-2570. (Pubitemid 32298198)
    • (2001) Journal of Neuroscience , vol.21 , Issue.8 , pp. 2561-2570
    • Gasparini, L.1    Gouras, G.K.2    Wang, R.3    Gross, R.S.4    Beal, M.F.5    Greengard, P.6    Xu, H.7
  • 29
    • 0030748390 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor-1 regulate tau phosphorylation in cultured human neurons
    • DOI 10.1074/jbc.272.31.19547
    • Hong M, Lee VM (1997) Insulin and insulin-like growth factor-1 regulate tau phosphorylation in cultured human neurons. J Biol Chem 272, 19547-19553. (Pubitemid 27337756)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.31 , pp. 19547-19553
    • Hong, M.1    Lee, V.M.-Y.2
  • 31
    • 0036917631 scopus 로고    scopus 로고
    • Serum insulin-like growth factor I regulates brain amyloid-β levels
    • DOI 10.1038/nm793
    • Carro E, Trejo JL, Gomez-Isla T, LeRoith D, Torres-Aleman I (2002) Serum insulin-like growth factor I regulates brain amyloid-beta levels. Nat Med 8, 1390-1397. (Pubitemid 36019424)
    • (2002) Nature Medicine , vol.8 , Issue.12 , pp. 1390-1397
    • Carro, E.1    Trejo, J.L.2    Gomez-Isla, T.3    Leroith, D.4    Torres-Aleman, I.5
  • 32
    • 33748438509 scopus 로고    scopus 로고
    • Blockade of the insulin-like growth factor I receptor in the choroid plexus originates Alzheimer's-like neuropathology in rodents: New cues into the human disease?
    • DOI 10.1016/j.neurobiolaging.2005.09.039, PII S019745800500309X
    • Carro E, Trejo JL, Spuch C, Bohl D, Heard JM, Torres-Aleman I (2006) Blockade of the insulin-like growth factor I receptor in the choroid plexus originates Alzheimer's-like neuropathology in rodents: new cues into the human disease? Neurobiol Aging 27, 1618-1631. (Pubitemid 44344848)
    • (2006) Neurobiology of Aging , vol.27 , Issue.11 , pp. 1618-1631
    • Carro, E.1    Trejo, J.L.2    Spuch, C.3    Bohl, D.4    Heard, J.M.5    Torres-Aleman, I.6
  • 33
    • 33847140273 scopus 로고    scopus 로고
    • Serum TNF-alpha levels are increased and correlate negatively with free IGF-I in Alzheimer disease
    • DOI 10.1016/j.neurobiolaging.2006.02.012, PII S0197458006000819
    • Alvarez A, Cacabelos R, Sanpedro C, Garcia-Fantini M, Aleixandre M (2007) Serum TNF-alpha levels are increased and correlate negatively with free IGF-I in Alzheimer disease. Neurobiol Aging 28, 533-536. (Pubitemid 46282207)
    • (2007) Neurobiology of Aging , vol.28 , Issue.4 , pp. 533-536
    • Alvarez, A.1    Cacabelos, R.2    Sanpedro, C.3    Garcia-Fantini, M.4    Aleixandre, M.5
  • 34
    • 33750963813 scopus 로고    scopus 로고
    • Nerve growth factor in treatment and pathogenesis of Alzheimer's disease
    • DOI 10.1016/j.pneurobio.2006.09.001, PII S0301008206001092
    • Williams BJ, Eriksdotter-Jonhagen M, Granholm AC (2006) Nerve growth factor in treatment and pathogenesis of Alzheimer's disease. Prog Neurobiol 80, 114-128. (Pubitemid 44739167)
    • (2006) Progress in Neurobiology , vol.80 , Issue.3 , pp. 114-128
    • Williams, B.J.1    Eriksdotter-Jonhagen, M.2    Granholm, A.-C.3
  • 35
    • 39049192182 scopus 로고    scopus 로고
    • On the molecular basis linking Nerve Growth Factor (NGF) to Alzheimer's disease
    • Capsoni S, Cattaneo A (2006) On the molecular basis linking Nerve Growth Factor (NGF) to Alzheimer's disease. Cell Mol Neurobiol 26, 619-633.
    • (2006) Cell Mol Neurobiol , vol.26 , pp. 619-633
    • Capsoni, S.1    Cattaneo, A.2
  • 36
    • 0029022112 scopus 로고
    • Nerve growth factor in Alzheimer's disease: Increased levels throughout the brain coupled with declines in nucleus basalis
    • Scott SA, Mufson EJ, Weingartner JA, Skau KA, Crutcher KA (1995) Nerve growth factor in Alzheimer's disease: increased levels throughout the brain coupled with declines in nucleus basalis. J Neurosci 15, 6213-6221.
    • (1995) J Neurosci , vol.15 , pp. 6213-6221
    • Scott, S.A.1    Mufson, E.J.2    Weingartner, J.A.3    Skau, K.A.4    Crutcher, K.A.5
  • 37
    • 0037125974 scopus 로고    scopus 로고
    • Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice
    • Capsoni S, Giannotta S, Cattaneo A (2002) Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice. Proc Natl Acad Sci U S A 99, 12432-12437.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 12432-12437
    • Capsoni, S.1    Giannotta, S.2    Cattaneo, A.3
  • 38
    • 37849050242 scopus 로고    scopus 로고
    • Neurotrophic factors in Alzheimer's disease: Role of axonal transport
    • Schindowski K, Belarbi K, Buee L (2008) Neurotrophic factors in Alzheimer's disease: role of axonal transport. Genes Brain Behav 7 Suppl 1, 43-56.
    • (2008) Genes Brain Behav , vol.7 , Issue.SUPPL. 1 , pp. 43-56
    • Schindowski, K.1    Belarbi, K.2    Buee, L.3
  • 41
    • 33847787591 scopus 로고    scopus 로고
    • Oligomeric amyloid decreases basal levels of brain-derived neurotrophic factor (BDNF) mRNA via specific downregulation of BDNF transcripts IV and V in differentiated human neuroblastoma cells
    • Garzon DJ, Fahnestock M (2007) Oligomeric amyloid decreases basal levels of brain-derived neurotrophic factor (BDNF) mRNA via specific downregulation of BDNF transcripts IV and V in differentiated human neuroblastoma cells. J Neurosci 27, 2628-2635.
    • (2007) J Neurosci , vol.27 , pp. 2628-2635
    • Garzon, D.J.1    Fahnestock, M.2
  • 42
    • 37049004787 scopus 로고    scopus 로고
    • Oligomers of β-amyloid peptide inhibit BDNF-induced arc expression in cultured cortical neurons
    • DOI 10.2174/156720507783018190
    • Echeverria V, Berman DE, Arancio O (2007) Oligomers of beta-amyloid peptide inhibit BDNF-induced arc expression in cultured cortical neurons. Curr Alz Res 4, 518-521. (Pubitemid 350248384)
    • (2007) Current Alzheimer Research , vol.4 , Issue.5 , pp. 518-521
    • Echeverria, V.1    Berman, D.E.2    Arancio, O.3
  • 43
    • 39149131761 scopus 로고    scopus 로고
    • 2A levels
    • DOI 10.1016/j.expneurol.2007.10.009, PII S0014488607003986
    • Christensen R, Marcussen AB, Wortwein G, Knudsen GM, Aznar S (2008) Abeta(1-42) injection causes memory impairment, lowered cortical and serum BDNF levels, and decreased hippocampal 5-HT(2A) levels. Exp Neurol 210, 164-171. (Pubitemid 351258077)
    • (2008) Experimental Neurology , vol.210 , Issue.1 , pp. 164-171
    • Christensen, R.1    Marcussen, A.B.2    Wortwein, G.3    Knudsen, G.M.4    Aznar, S.5
  • 44
    • 25844490528 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor induces a rapid dephosphorylation of tau protein through a PI-3Kinase signalling mechanism
    • DOI 10.1111/j.1460-9568.2005.04290.x
    • Elliott E, Atlas R, Lange A, Ginzburg I (2005) Brain-derived neurotrophic factor induces a rapid dephosphorylation of tau protein through a PI-3 Kinase signalling mechanism. Eur J Neurosci 22, 1081-1089. (Pubitemid 41395371)
    • (2005) European Journal of Neuroscience , vol.22 , Issue.5 , pp. 1081-1089
    • Elliott, E.1    Atlas, R.2    Lange, A.3    Ginzburg, I.4
  • 45
    • 0030764732 scopus 로고    scopus 로고
    • Amyloidogenic role of cytokine TGF-β1 in transgenic mice and in Alzheimer's disease
    • DOI 10.1038/39321
    • Wyss-Coray T, Masliah E, Mallory M, McConlogue L, Johnson-Wood K, Lin C, Mucke, L (1997) Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease. Nature 389, 603-606. (Pubitemid 27446177)
    • (1997) Nature , vol.389 , Issue.6651 , pp. 603-606
    • Wyss-Coray, T.1    Masliah, E.2    Mallory, M.3    McConlogue, L.4    Johnson-Wood, K.5    Lin, C.6    Mucke, L.7
  • 46
    • 0036098247 scopus 로고    scopus 로고
    • Cerebrovascular transforming growth factor-β contributes to inflammation in the Alzheimer's disease brain
    • Grammas P, Ovase R (2002) Cerebrovascular transforming growth factor-beta contributes to inflammation in the Alzheimer's disease brain. Am J Pathol 160, 1583-1587. (Pubitemid 34525638)
    • (2002) American Journal of Pathology , vol.160 , Issue.5 , pp. 1583-1587
    • Grammas, P.1    Ovase, R.2
  • 47
    • 33846821659 scopus 로고    scopus 로고
    • Neurofibrillary tangles may interfere with Smad 2/3 signaling in neurons
    • Chalmers KA, Love S (2007) Neurofibrillary tangles may interfere with Smad 2/3 signaling in neurons. J Neuropathol Exp Neurol 66, 158-167.
    • (2007) J Neuropathol Exp Neurol , vol.66 , pp. 158-167
    • Chalmers, K.A.1    Love, S.2
  • 48
    • 33750320547 scopus 로고    scopus 로고
    • Altered subcellular location of phosphorylated Smads in Alzheimer's disease
    • DOI 10.1111/j.1460-9568.2006.05109.x
    • Ueberham U, Ueberham E, Gruschka H, Arendt T (2006) Altered subcellular location of phosphorylated Smads in Alzheimer's disease. Eur J Neurosci 24, 2327-2334. (Pubitemid 44622353)
    • (2006) European Journal of Neuroscience , vol.24 , Issue.8 , pp. 2327-2334
    • Ueberham, U.1    Ueberham, E.2    Gruschka, H.3    Arendt, T.4
  • 49
    • 33750591504 scopus 로고    scopus 로고
    • Dysfunction of TGF-β signaling in Alzheimer's disease
    • DOI 10.1172/JCI30284
    • Das P, Golde T (2006) Dysfunction of TGF-β signaling in Alzheimer's disease. J Clin Invest 116, 2855-2857. (Pubitemid 44684467)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.11 , pp. 2855-2857
    • Das, P.1    Golde, T.2
  • 50
    • 37549066655 scopus 로고    scopus 로고
    • TGF-beta1 is increased in a transgenic mouse model of familial Alzheimer's disease and causes neuronal apoptosis
    • Salins P, He Y, Glazner G, Kashour T, Amara F (2008) TGF-beta1 is increased in a transgenic mouse model of familial Alzheimer's disease and causes neuronal apoptosis. Neurosci Lett 430, 81-86.
    • (2008) Neurosci Lett , vol.430 , pp. 81-86
    • Salins, P.1    He, Y.2    Glazner, G.3    Kashour, T.4    Amara, F.5
  • 51
  • 53
    • 1242338809 scopus 로고    scopus 로고
    • Co-accumulation of vascular endothelial growth factor with β-amyloid in the brain of patients with Alzheimer's disease
    • DOI 10.1016/S0197-4580(03)00111-8
    • Yang S-P, Bae D-G, Kang HJ, Gwag BJ, Gho YS, Chae C-B (2004) Co-accumulation of vascular endothelial growth factor with beta-amyloid in the brain of patients with Alzheimer's disease. Neurobiol Aging 25, 283-290. (Pubitemid 38220962)
    • (2004) Neurobiology of Aging , vol.25 , Issue.3 , pp. 283-290
    • Yang, S.-P.1    Bae, D.-G.2    Kang, H.J.3    Gwag, B.J.4    Gho, Y.S.5    Chae, C.-B.6
  • 54
    • 28744437870 scopus 로고    scopus 로고
    • Connective tissue growth factor (CTGF) expression in the brain is a downstream effector of insulin resistance-associated promotion of Alzheimer's disease β-amyloid neuropathology
    • DOI 10.1096/fj.05-4359fje
    • Zhao Z, Ho L, Wang J, Qin W, Festa ED, Mobbs C, Hof P, Rocher A, Masur S, Haroutunian V, Pasinetti GM(2005) Connective tissue growth factor (CTGF) expression in the brain is a downstream effector of insulin resistance- associated promotion of Alzheimer's disease beta-amyloid neuropathology. FASEB J 19, 2081-2082. (Pubitemid 41759772)
    • (2005) FASEB Journal , vol.19 , Issue.14 , pp. 2081-2082
    • Zhao, Z.1    Ho, L.2    Wang, J.3    Qin, W.4    Festa, E.D.5    Mobbs, C.6    Hof, P.7    Rocher, A.8    Masur, S.9    Haroutunian, V.10    Pasinetti, G.M.11
  • 58
    • 45549097081 scopus 로고    scopus 로고
    • Site-specific blockade of RAGE-Vd prevents amyloid-beta oligomer neurotoxicity
    • Sturchler E, Galichet A, Weibel M, Leclerc E, Heizmann CW (2008) Site-specific blockade of RAGE-Vd prevents amyloid-beta oligomer neurotoxicity. J Neurosci 28, 5149-5158.
    • (2008) J Neurosci , vol.28 , pp. 5149-5158
    • Sturchler, E.1    Galichet, A.2    Weibel, M.3    Leclerc, E.4    Heizmann, C.W.5
  • 59
    • 0035847269 scopus 로고    scopus 로고
    • Immunohistochemical distribution of the receptor for advanced glycation end products in neurons and astrocytes in Alzheimer's disease
    • DOI 10.1016/S0006-8993(00)03075-4, PII S0006899300030754
    • Sasaki N, Toki S, Chowei H, Saito T, Nakano N, Hayashi Y, Takeuchi M, Makita Z (2001) Immunohistochemical distribution of the receptor for advanced glycation end products in neurons and astrocytes in Alzheimer's disease. Brain Res 888, 256-262. (Pubitemid 32058790)
    • (2001) Brain Research , vol.888 , Issue.2 , pp. 256-262
    • Sasaki, N.1    Toki, S.2    Chowei, H.3    Saito, T.4    Nakano, N.5    Hayashi, Y.6    Takeuchi, M.7    Makita, Z.8
  • 60
    • 0032029363 scopus 로고    scopus 로고
    • AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. the AGE concept
    • DOI 10.1016/S0008-6363(97)00233-2, PII S0008636397002332
    • Bierhaus A, Hofmann MA, Ziegler R, Narworth PP (1998) AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept. Cardiovasc Res 37, 586-600. (Pubitemid 28231153)
    • (1998) Cardiovascular Research , vol.37 , Issue.3 , pp. 586-600
    • Bierhaus, A.1    Hofmann, M.A.2    Ziegler, R.3    Nawroth, P.P.4
  • 65
    • 44449179863 scopus 로고    scopus 로고
    • Possible involvement of advanced glycation end-products (AGEs) in the pathogenesis of Alzheimer's disease
    • DOI 10.2174/138161208784139693
    • Takeuchi M, Yamagishi S (2008) Possible involvement of advanced glycation end-products (AGEs) in the pathogenesis of Alzheimer's disease. Current Pharm Des, 14, 973-980. (Pubitemid 351753285)
    • (2008) Current Pharmaceutical Design , vol.14 , Issue.10 , pp. 973-978
    • Takeuchi, M.1    Yamagishi, S.-I.2
  • 67
    • 2542489864 scopus 로고    scopus 로고
    • Advanced glycation endproducts and pro-inflammatory cytokines in transgenic Tg2576 mice with amyloid plaque pathology
    • DOI 10.1046/j.1471-4159.2003.01837.x
    • Münch G, Apelt J, Rosemarie-Kientsch-Engel, Stahl P, Luth HJ, Scliebs R (2003) Advanced glycation endproducts and pro-inflammatory cytokines in transgenic Tg2576 mice with amyloid plaque pathology. J Neurochem 86, 283-289. (Pubitemid 36842428)
    • (2003) Journal of Neurochemistry , vol.86 , Issue.2 , pp. 283-289
    • Munch, G.1    Apelt, J.2    Kientsch-Engel, R.3    Stahl, P.4    Luth, H.J.5    Schliebs, R.6
  • 68
    • 0037293474 scopus 로고    scopus 로고
    • β-Amyloid peptide potentiates inflammatory responses induced by lipopolysaccharide, interferon -γ and 'advanced glycation endproducts' in a murine microglia cell line
    • DOI 10.1046/j.1460-9568.2003.02506.x
    • Gasic-Milenkovic J, Dukic-Stefanovic S, Deuther-Conrad W, Gartner U, Munch G (2003) Beta-amyloid peptide potentiates inflammatory responses induced by lipopolysaccharide, interferon -gamma and 'advanced glycation endproducts' in a murine microglia cell line. Eur J Neurosci 17, 813-821. (Pubitemid 36315251)
    • (2003) European Journal of Neuroscience , vol.17 , Issue.4 , pp. 813-821
    • Gasic-Milenkovic, J.1    Dukic-Stefanovic, S.2    Deuther-Conrad, W.3    Gartner, U.4    Munch, G.5
  • 71
    • 0036220465 scopus 로고    scopus 로고
    • Connective tissue growth factor/IGF-binding protein-related protein-2 is a mediator in the induction of fibronectin by advanced glycosylation end-products in human dermal fibroblasts
    • DOI 10.1210/en.143.4.1260
    • Twigg SM, Joly AH, Chen MM, Tsubaki J, Kim HS, Hwa V, Oh Y, Rosenfeld RG (2002) Connective tissue growth factor/IGF-binding protein-related protein-2 is a mediator in the induction of fibronectin by advanced glycosylation end-products in human dermal fibroblasts. Endocrinology 143, 1260-1269. (Pubitemid 34274355)
    • (2002) Endocrinology , vol.143 , Issue.4 , pp. 1260-1269
    • Twigg, S.M.1    Joly, A.H.2    Chen, M.M.3    Tsubaki, J.4    Ho-Seong, K.I.M.5    Vivian, H.W.A.6    Youngman, O.H.7    Rosenfeld, R.G.8
  • 72
    • 0036892894 scopus 로고    scopus 로고
    • Renal connective tissue growth factor induction in experimental diabetes is prevented by aminoguanidine
    • DOI 10.1210/en.2002-220619
    • Twigg SM, Cao Z, McLennan SV, Burns WC, Brammar G, Forbes JM, Cooper ME (2002) Renal connective tissue growth factor induction in experimental diabetes is prevented by aminoguanidine. Endocrinology 143, 4907-4915. (Pubitemid 35397630)
    • (2002) Endocrinology , vol.143 , Issue.12 , pp. 4907-4915
    • Twigg, S.M.1    Cao, Z.2    McLennan, S.V.3    Burns, W.C.4    Brammar, G.5    Forbes, J.M.6    Cooper, M.E.7
  • 73
    • 0036829609 scopus 로고    scopus 로고
    • ALT-946 and aminoguanidine, inhibitors of advanced glycation, improve severe nephropathy in the diabetic transgenic (mREN-2)27 rat
    • Wilkinson-Berka JL, Kelly DJ, Koerner SM, Jaworski K, Davis B, Thallas V, Cooper ME (2002) ALT-946 and aminoguanidine, inhibitors of advanced glycation, improve severe nephropathy in the diabetic transgenic (mREN-2)27 rat. Diabetes 51, 3283-3289. (Pubitemid 35246975)
    • (2002) Diabetes , vol.51 , Issue.11 , pp. 3283-3289
    • Wilkinson-Berka, J.L.1    Kelly, D.J.2    Koerner, S.M.3    Jaworski, K.4    Davis, B.5    Thallas, V.6    Cooper, M.E.7
  • 74
    • 0035047352 scopus 로고    scopus 로고
    • Advanced glycosylation end products up-regulate connective tissue growth factor (insulin-like growth factor-binding protein-related protein 2) in human fibroblasts: A potential mechanism for expansion of extracellular matrix in diabetes mellitus
    • DOI 10.1210/en.142.5.1760
    • Twigg SM, Chen MM, Joly AH, Chakrapani SD, Tsubaki J, Kim HS, Oh Y, Rosenfeld RG (2001) Advanced glycosylation end products up-regulate connective tissue growth factor (insulin-like growth factor-binding protein-related protein 2) in human fibroblasts: a potential mechanism for expansion of extracellular matrix in diabetes mellitus. Endocrinology 142, 1760-1769. (Pubitemid 32405931)
    • (2001) Endocrinology , vol.142 , Issue.5 , pp. 1760-1769
    • Twigg, S.M.1    Chen, M.M.2    Joly, A.H.3    Chakrapani, S.D.4    Tsubaki, J.5    Kim, H.-S.6    Oh, Y.7    Rosenfeld, R.G.8
  • 75
    • 0141483457 scopus 로고    scopus 로고
    • The breakdown of pre-existing advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes
    • Forbes JM, Thallas V, Thomas MC, Founds HW, Burns WC, Jerums G, Cooper ME (2003) The breakdown of pre-existing advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes. FASEB J 17, 1762-1764
    • (2003) FASEB J , vol.17 , pp. 1762-1764
    • Forbes, J.M.1    Thallas, V.2    Thomas, M.C.3    Founds, H.W.4    Burns, W.C.5    Jerums, G.6    Cooper, M.E.7
  • 78
    • 0034840664 scopus 로고    scopus 로고
    • Involvement of microglial receptor for advanced glycation endproducts (RAGE)in Alzheimer's disease: Identification of a cellular activation mechanism
    • DOI 10.1006/exnr.2001.7732
    • Lue LF, Walker DG, Brachova L, Beach TG, Rogers J, Schmidt AM, Stern DM, Yan SD (2001) Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: identification of a cellular activation mechanism. Exp Neurol, 171, 29-45. (Pubitemid 32848443)
    • (2001) Experimental Neurology , vol.171 , Issue.1 , pp. 29-45
    • Lue, L.-F.1    Walker, D.G.2    Brachova, L.3    Beach, T.G.4    Rogers, J.5    Schmidt, A.M.6    Stern, D.M.7    Yan, S.D.8
  • 81
    • 33645830313 scopus 로고    scopus 로고
    • Vicious cycles within the neuropathophysiologic mechanisms of Alzheimer's disease
    • Standridge JB (2006), Vicious cycles within the neuropathophysiologic mechanisms of Alzheimer's disease. Curr Alzheimer Res 3, 95-108.
    • (2006) Curr Alzheimer Res , vol.3 , pp. 95-108
    • Standridge, J.B.1
  • 82
    • 15744402494 scopus 로고    scopus 로고
    • Glyceraldehyde-derived advanced glycation end-products preferentially induce VEGF expression and reduce GDNF expression in human astrocytes
    • DOI 10.1016/j.bbrc.2005.03.001
    • Miyajima H, Osanai M, Chiba H, Nishikiori N, Kojima T, Ohtsuka K, Sawada. N (2005) Glyceraldehyde-derived advanced glycation end-products preferentially induce VEGF expression and reduce GDNF expression in human astrocytes. Biochem Biophys Res Commun 330, 361-366. (Pubitemid 40417654)
    • (2005) Biochemical and Biophysical Research Communications , vol.330 , Issue.2 , pp. 361-366
    • Miyajima, H.1    Osanai, M.2    Chiba, H.3    Nishikiori, N.4    Kojima, T.5    Ohtsuka, K.6    Sawada, N.7


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