메뉴 건너뛰기




Volumn 390, Issue 5-6, 2009, Pages 379-390

The liaison between apoptotic cells and macrophages - The end programs the beginning

Author keywords

Apoptosis; NF B; Phagocytosis; Phosphatidylserine; Sphingosine 1 phosphate; Transforming growth factor (TGF )

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 67649626015     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2009.048     Document Type: Review
Times cited : (35)

References (129)
  • 2
    • 0345731228 scopus 로고    scopus 로고
    • The opsonin MFG-E8 is a ligand for the avb5 integrin and triggers DOCK180-dependentRac1 activation for the phagocytosis of apoptotic cells
    • Akakura, S., Singh, S., Spataro, M., Akakura, R., Kim, J.I., Albert, M.L., and Birge, R.B. (2004). The opsonin MFG-E8 is a ligand for the avb5 integrin and triggers DOCK180-dependentRac1 activation for the phagocytosis of apoptotic cells. Exp. Cell Res. 292, 403-416.
    • (2004) Exp. Cell Res , vol.292 , pp. 403-416
    • Akakura, S.1    Singh, S.2    Spataro, M.3    Akakura, R.4    Kim, J.I.5    Albert, M.L.6    Birge, R.B.7
  • 3
    • 1542511202 scopus 로고    scopus 로고
    • Death-defying immunity: Do apoptotic cells influence antigen processing and presentation?
    • Albert, M.L. (2004). Death-defying immunity: do apoptotic cells influence antigen processing and presentation? Nat. Rev. Immunol. 4, 223-231.
    • (2004) Nat. Rev. Immunol , vol.4 , pp. 223-231
    • Albert, M.L.1
  • 7
    • 0036187615 scopus 로고    scopus 로고
    • The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
    • Bingle, L., Brown, N.J., and Lewis, C.E. (2002). The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J. Pathol. 196, 254-265.
    • (2002) J. Pathol , vol.196 , pp. 254-265
    • Bingle, L.1    Brown, N.J.2    Lewis, C.E.3
  • 8
    • 0034769118 scopus 로고    scopus 로고
    • Nitric oxide and the immune response
    • Bogdan, C. (2001). Nitric oxide and the immune response. Nat. Immunol. 2, 907-916.
    • (2001) Nat. Immunol , vol.2 , pp. 907-916
    • Bogdan, C.1
  • 10
    • 2342464085 scopus 로고    scopus 로고
    • The two NF-κB activation pathways and their role in innate and adaptive immunity
    • Bonizzi, G. and Karin, M. (2004). The two NF-κB activation pathways and their role in innate and adaptive immunity. Trends Immunol. 25, 280-288.
    • (2004) Trends Immunol , vol.25 , pp. 280-288
    • Bonizzi, G.1    Karin, M.2
  • 11
    • 0032584675 scopus 로고    scopus 로고
    • The cyclosporin A-sensitive nuclear factor of activated T cells (NFAT) proteins are expressed in vascular smooth muscle cells. Differential localization of NFAT isoforms and induction of NFAT-mediated transcription by phospholipase C-coupled cell surface receptors
    • Boss, V., Abbott, K.L., Wang, X.F., Pavlath, G.K., and Murphy, T.J. (1998). The cyclosporin A-sensitive nuclear factor of activated T cells (NFAT) proteins are expressed in vascular smooth muscle cells. Differential localization of NFAT isoforms and induction of NFAT-mediated transcription by phospholipase C-coupled cell surface receptors. J. Biol. Chem. 273, 19664-19671.
    • (1998) J. Biol. Chem , vol.273 , pp. 19664-19671
    • Boss, V.1    Abbott, K.L.2    Wang, X.F.3    Pavlath, G.K.4    Murphy, T.J.5
  • 13
    • 0028979170 scopus 로고
    • Transforming growth factor-β stimulates arginase activity in macrophages. Implications for the regulation of macrophage cytotoxicity
    • Boutard, V., Havouis, R., Fouqueray, B., Philippe, C., Moulinoux, J.P., and Baud, L. (1995). Transforming growth factor-β stimulates arginase activity in macrophages. Implications for the regulation of macrophage cytotoxicity. J. Immunol. 155, 2077-2084.
    • (1995) J. Immunol , vol.155 , pp. 2077-2084
    • Boutard, V.1    Havouis, R.2    Fouqueray, B.3    Philippe, C.4    Moulinoux, J.P.5    Baud, L.6
  • 14
    • 38149064475 scopus 로고    scopus 로고
    • Apoptotic cell recognition: Will the real phosphatidylserine receptor(s) please stand up?
    • Bratton, D.L. and Henson, P.M. (2008). Apoptotic cell recognition: will the real phosphatidylserine receptor(s) please stand up? Curr. Biol. 18, R76-R79.
    • (2008) Curr. Biol , vol.18
    • Bratton, D.L.1    Henson, P.M.2
  • 15
    • 0030697996 scopus 로고    scopus 로고
    • Appearance of phosphatidylserine on apoptotic cells requires calcium-mediated nonspecific flip-flop and is enhanced by loss of the aminophospholipid translocase
    • Bratton, D.L., Fadok, V.A., Richter, D.A., Kailey, J.M., Guthrie, L.A., and Henson, P.M. (1997). Appearance of phosphatidylserine on apoptotic cells requires calcium-mediated nonspecific flip-flop and is enhanced by loss of the aminophospholipid translocase. J. Biol. Chem. 272, 26159-26165.
    • (1997) J. Biol. Chem , vol.272 , pp. 26159-26165
    • Bratton, D.L.1    Fadok, V.A.2    Richter, D.A.3    Kailey, J.M.4    Guthrie, L.A.5    Henson, P.M.6
  • 17
    • 0037062989 scopus 로고    scopus 로고
    • Apoptosis disables CD31-mediated cell detachment from phagocytes promoting binding and engulfment
    • Brown, S., Heinisch, I., Ross, E., Shaw, K., Buckley, C.D., and Savill, J. (2002). Apoptosis disables CD31-mediated cell detachment from phagocytes promoting binding and engulfment. Nature 418, 200-203.
    • (2002) Nature , vol.418 , pp. 200-203
    • Brown, S.1    Heinisch, I.2    Ross, E.3    Shaw, K.4    Buckley, C.D.5    Savill, J.6
  • 19
    • 0034960320 scopus 로고    scopus 로고
    • TGF-β released by apoptotic T cells contributes to an immunosuppressive milieu
    • Chen, W., Frank, M.E., Jin, W., and Wahl, S.M. (2001). TGF-β released by apoptotic T cells contributes to an immunosuppressive milieu. Immunity 14, 715-725.
    • (2001) Immunity , vol.14 , pp. 715-725
    • Chen, W.1    Frank, M.E.2    Jin, W.3    Wahl, S.M.4
  • 20
    • 0028873889 scopus 로고
    • Expression of nitric oxide synthase in human central nervous system tumors
    • Cobbs, C.S., Brenman, J.E., Aldape, K.D., Bredt, D.S., and Israel, M.A. (1995). Expression of nitric oxide synthase in human central nervous system tumors. Cancer Res. 55, 727-730.
    • (1995) Cancer Res , vol.55 , pp. 727-730
    • Cobbs, C.S.1    Brenman, J.E.2    Aldape, K.D.3    Bredt, D.S.4    Israel, M.A.5
  • 22
    • 1642536490 scopus 로고    scopus 로고
    • Innate immune discrimination of apoptotic cells: Repression of proinflammatory macrophage transcription is coupled directly to specific recognition
    • Cvetanovic, M. and Ucker, D.S. (2004). Innate immune discrimination of apoptotic cells: repression of proinflammatory macrophage transcription is coupled directly to specific recognition. J. Immunol. 172, 880-889.
    • (2004) J. Immunol , vol.172 , pp. 880-889
    • Cvetanovic, M.1    Ucker, D.S.2
  • 23
    • 23644436020 scopus 로고    scopus 로고
    • Heme oxygenase-1 expression in disease states
    • Deshane, J., Wright, M., and Agarwal, A. (2005). Heme oxygenase-1 expression in disease states. Acta Biochim. Pol. 52, 273-284.
    • (2005) Acta Biochim. Pol , vol.52 , pp. 273-284
    • Deshane, J.1    Wright, M.2    Agarwal, A.3
  • 25
    • 0034790277 scopus 로고    scopus 로고
    • Suppression by apoptotic cells defines tumor necrosis factor- mediated induction of glomerular mesangial cell apoptosis by activated macrophages
    • Duffield, J.S., Ware, C.F., Ryffel, B., and Savill, J. (2001). Suppression by apoptotic cells defines tumor necrosis factor- mediated induction of glomerular mesangial cell apoptosis by activated macrophages. Am. J. Pathol. 159, 1397-1404.
    • (2001) Am. J. Pathol , vol.159 , pp. 1397-1404
    • Duffield, J.S.1    Ware, C.F.2    Ryffel, B.3    Savill, J.4
  • 26
    • 34547656330 scopus 로고    scopus 로고
    • Immunological consequences of apoptotic cell phagocytosis
    • Erwig, L.P. and Henson, P.M. (2007). Immunological consequences of apoptotic cell phagocytosis. Am. J. Pathol. 171, 2-8.
    • (2007) Am. J. Pathol , vol.171 , pp. 2-8
    • Erwig, L.P.1    Henson, P.M.2
  • 27
    • 0032519925 scopus 로고    scopus 로고
    • Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-β, PGE2, and PAF
    • Fadok, V.A., Bratton, D.L., Konowal, A., Freed, P.W., Westcott, J.Y., and Henson, P.M. (1998). Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-β, PGE2, and PAF. J. Clin. Invest. 101, 890-898.
    • (1998) J. Clin. Invest , vol.101 , pp. 890-898
    • Fadok, V.A.1    Bratton, D.L.2    Konowal, A.3    Freed, P.W.4    Westcott, J.Y.5    Henson, P.M.6
  • 29
    • 0037115158 scopus 로고    scopus 로고
    • Reactive oxygen species and cell signaling: Respiratory burst in macrophage signaling
    • Forman, H.J. and Torres, M. (2002). Reactive oxygen species and cell signaling: respiratory burst in macrophage signaling. Am. J. Respir. Crit. Care Med. 166, S4-S8.
    • (2002) Am. J. Respir. Crit. Care Med , vol.166
    • Forman, H.J.1    Torres, M.2
  • 30
    • 0034725570 scopus 로고    scopus 로고
    • Regulation of phospholipid scramblase activity during apoptosis and cell activation by protein kinase Cd
    • Frasch, S.C., Henson, P.M., Kailey, J.M., Richter, D.A., Janes, M.S., Fadok, V.A., and Bratton, D.L. (2000). Regulation of phospholipid scramblase activity during apoptosis and cell activation by protein kinase Cd. J. Biol. Chem. 275, 23065-23073.
    • (2000) J. Biol. Chem , vol.275 , pp. 23065-23073
    • Frasch, S.C.1    Henson, P.M.2    Kailey, J.M.3    Richter, D.A.4    Janes, M.S.5    Fadok, V.A.6    Bratton, D.L.7
  • 32
    • 33846025798 scopus 로고    scopus 로고
    • Apoptotic cells, through transforming growth factor-β, coordinately induce anti-inflammatory and suppress pro-inflammatory eicosanoid and NO synthesis in murine macrophages
    • Freire-de-Lima, C.G., Xiao, Y.Q., Gardai, S.J., Bratton, D.L., Schiemann, W.P., and Henson, P.M. (2006). Apoptotic cells, through transforming growth factor-β, coordinately induce anti-inflammatory and suppress pro-inflammatory eicosanoid and NO synthesis in murine macrophages. J. Biol. Chem. 281, 38376-38384.
    • (2006) J. Biol. Chem , vol.281 , pp. 38376-38384
    • Freire-de-Lima, C.G.1    Xiao, Y.Q.2    Gardai, S.J.3    Bratton, D.L.4    Schiemann, W.P.5    Henson, P.M.6
  • 33
    • 0032494144 scopus 로고    scopus 로고
    • Antiinflammatory effects of CD95 ligand (FasL)-induced apoptosis
    • Gao, Y., Herndon, J.M., Zhang, H., Griffith, T.S., and Ferguson, T.A. (1998). Antiinflammatory effects of CD95 ligand (FasL)-induced apoptosis. J. Exp. Med. 188, 887-896.
    • (1998) J. Exp. Med , vol.188 , pp. 887-896
    • Gao, Y.1    Herndon, J.M.2    Zhang, H.3    Griffith, T.S.4    Ferguson, T.A.5
  • 34
    • 20444417421 scopus 로고    scopus 로고
    • Coactivators and corepressors of NF-κB in IκB a gene promoter
    • Gao, Z., Chiao, P., Zhang, X., Lazar, M.A., Seto, E., Young, H.A., and Ye, J. (2005). Coactivators and corepressors of NF-κB in IκB a gene promoter. J. Biol. Chem. 280, 21091-21098.
    • (2005) J. Biol. Chem , vol.280 , pp. 21091-21098
    • Gao, Z.1    Chiao, P.2    Zhang, X.3    Lazar, M.A.4    Seto, E.5    Young, H.A.6    Ye, J.7
  • 35
    • 34249792107 scopus 로고    scopus 로고
    • Apoptotic cells selectively suppress the Th1 cytokine interferon γ in stimulated human peripheral blood mononuclear cells and shift the Th1/Th2 balance towards Th2
    • Girkontaite, I., Urbonaviciute, V., Maseda, D., Neubert, K., Herrmann, M., and Voll, R.E. (2007). Apoptotic cells selectively suppress the Th1 cytokine interferon γ in stimulated human peripheral blood mononuclear cells and shift the Th1/Th2 balance towards Th2. Autoimmunity 40, 327-330.
    • (2007) Autoimmunity , vol.40 , pp. 327-330
    • Girkontaite, I.1    Urbonaviciute, V.2    Maseda, D.3    Neubert, K.4    Herrmann, M.5    Voll, R.E.6
  • 37
    • 0037468614 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate inhibits acid sphingomyelinase and blocks apoptosis in macrophages
    • Gomez-Munoz, A., Kong, J., Salh, B., and Steinbrecher, U.P. (2003). Sphingosine-1-phosphate inhibits acid sphingomyelinase and blocks apoptosis in macrophages. FEBS Lett. 539, 56-60.
    • (2003) FEBS Lett , vol.539 , pp. 56-60
    • Gomez-Munoz, A.1    Kong, J.2    Salh, B.3    Steinbrecher, U.P.4
  • 38
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • Gordon, S. (2003). Alternative activation of macrophages. Nat. Rev. Immunol. 3, 23-35.
    • (2003) Nat. Rev. Immunol , vol.3 , pp. 23-35
    • Gordon, S.1
  • 39
    • 33751519372 scopus 로고    scopus 로고
    • Oxidized phosphatidylserine-CD36 interactions play an essential role in macrophage-dependent phagocytosis of apoptotic cells
    • Greenberg, M.E., Sun, M., Zhang, R., Febbraio, M., Silverstein, R., and Hazen, S.L. (2006). Oxidized phosphatidylserine-CD36 interactions play an essential role in macrophage-dependent phagocytosis of apoptotic cells. J. Exp. Med. 203, 2613-2625.
    • (2006) J. Exp. Med , vol.203 , pp. 2613-2625
    • Greenberg, M.E.1    Sun, M.2    Zhang, R.3    Febbraio, M.4    Silverstein, R.5    Hazen, S.L.6
  • 41
    • 48749121214 scopus 로고    scopus 로고
    • Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a 'come-and-get-me' signal
    • Gude, D.R., Alvarez, S.E., Paugh, S.W., Mitra, P., Yu, J., Griffiths, R., Barbour, S.E., Milstien, S., and Spiegel, S. (2008). Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a 'come-and-get-me' signal. FASEB J. 22, 2629-2638.
    • (2008) FASEB J , vol.22 , pp. 2629-2638
    • Gude, D.R.1    Alvarez, S.E.2    Paugh, S.W.3    Mitra, P.4    Yu, J.5    Griffiths, R.6    Barbour, S.E.7    Milstien, S.8    Spiegel, S.9
  • 43
    • 33644842973 scopus 로고    scopus 로고
    • MFG-E8-dependent clearance of apoptotic cells, and autoimmunity caused by its failure
    • Hanayama, R., Miyasaka, K., Nakaya, M., and Nagata, S. (2006). MFG-E8-dependent clearance of apoptotic cells, and autoimmunity caused by its failure. Curr. Dir. Autoimmun. 9, 162-172.
    • (2006) Curr. Dir. Autoimmun , vol.9 , pp. 162-172
    • Hanayama, R.1    Miyasaka, K.2    Nakaya, M.3    Nagata, S.4
  • 44
    • 33846434062 scopus 로고    scopus 로고
    • Shaping of monocyte and macrophage function by adenosine receptors
    • Hasko, G., Pacher, P., Deitch, E.A., and Vizi, E.S. (2007). Shaping of monocyte and macrophage function by adenosine receptors. Pharmacol. Ther. 113, 264-275.
    • (2007) Pharmacol. Ther , vol.113 , pp. 264-275
    • Hasko, G.1    Pacher, P.2    Deitch, E.A.3    Vizi, E.S.4
  • 46
    • 0036431585 scopus 로고    scopus 로고
    • Up-regulation of production of TGF-β and IL-4 and down-regulation of IL-6 by apoptotic human bronchial epithelial cells
    • Hodge, S., Hodge, G., Flower, R., Reynolds, P.N., Scicchitano, R., and Holmes, M. (2002). Up-regulation of production of TGF-β and IL-4 and down-regulation of IL-6 by apoptotic human bronchial epithelial cells. Immunol. Cell Biol. 80, 537-543.
    • (2002) Immunol. Cell Biol , vol.80 , pp. 537-543
    • Hodge, S.1    Hodge, G.2    Flower, R.3    Reynolds, P.N.4    Scicchitano, R.5    Holmes, M.6
  • 47
    • 0036143018 scopus 로고    scopus 로고
    • Phosphatidylserine- dependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation
    • Huynh, M.L., Fadok, V.A., and Henson, P.M. (2002). Phosphatidylserine- dependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation. J. Clin. Invest. 109, 41-50.
    • (2002) J. Clin. Invest , vol.109 , pp. 41-50
    • Huynh, M.L.1    Fadok, V.A.2    Henson, P.M.3
  • 48
    • 0036551246 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate induces chemotaxis of immature and modulates cytokine-release in mature human dendritic cells for emergence of Th2 immune responses
    • Idzko, M., Panther, E., Corinti, S., Morelli, A., Ferrari, D., Herouy, Y., Dichmann, S., Mockenhaupt, M., Gebicke-Haerter, P., Di Virgilio, F., et al. (2002). Sphingosine 1-phosphate induces chemotaxis of immature and modulates cytokine-release in mature human dendritic cells for emergence of Th2 immune responses. FASEB J. 16, 625-627.
    • (2002) FASEB J , vol.16 , pp. 625-627
    • Idzko, M.1    Panther, E.2    Corinti, S.3    Morelli, A.4    Ferrari, D.5    Herouy, Y.6    Dichmann, S.7    Mockenhaupt, M.8    Gebicke-Haerter, P.9    Di Virgilio, F.10
  • 49
    • 54049147721 scopus 로고    scopus 로고
    • Sumoylation of peroxisome proliferator-activated receptor γ by apoptotic cells prevents lipopolysaccharide-induced NCoR removal from κB binding sites mediating transrepression of proinflammatory cytokines
    • Jennewein, C., Kuhn, A.M., Schmidt, M.V., Meilladec-Jullig, V., von Knethen, A., Gonzalez, F.J., and Brune, B. (2008). Sumoylation of peroxisome proliferator-activated receptor γ by apoptotic cells prevents lipopolysaccharide-induced NCoR removal from κB binding sites mediating transrepression of proinflammatory cytokines. J. Immunol. 181, 5646-5652.
    • (2008) J. Immunol , vol.181 , pp. 5646-5652
    • Jennewein, C.1    Kuhn, A.M.2    Schmidt, M.V.3    Meilladec-Jullig, V.4    von Knethen, A.5    Gonzalez, F.J.6    Brune, B.7
  • 50
    • 33747036162 scopus 로고    scopus 로고
    • Recognition of apoptotic cells by macrophages activates the peroxisome proliferator-activated receptor-γ and attenuates the oxidative burst
    • Johann, A.M., von Knethen, A., Lindemann, D., and Brune, B. (2006). Recognition of apoptotic cells by macrophages activates the peroxisome proliferator-activated receptor-γ and attenuates the oxidative burst. Cell Death Differ. 13, 1533-1540.
    • (2006) Cell Death Differ , vol.13 , pp. 1533-1540
    • Johann, A.M.1    von Knethen, A.2    Lindemann, D.3    Brune, B.4
  • 51
    • 34548476253 scopus 로고    scopus 로고
    • Apoptotic cells induce arginase II in macrophages, thereby attenuating NO production
    • Johann, A.M., Barra, V., Kuhn, A.M., Weigert, A., von Knethen, A., and Brune, B. (2007). Apoptotic cells induce arginase II in macrophages, thereby attenuating NO production. FASEB J. 21, 2704-2712.
    • (2007) FASEB J , vol.21 , pp. 2704-2712
    • Johann, A.M.1    Barra, V.2    Kuhn, A.M.3    Weigert, A.4    von Knethen, A.5    Brune, B.6
  • 52
    • 40449098552 scopus 로고    scopus 로고
    • Apoptotic cell-derived sphingosine-1-phosphate promotes HuR-dependent cyclooxygenase-2 mRNA stabilization and protein expression
    • Johann, A.M., Weigert, A., Eberhardt, W., Kuhn, A.M., Barra, V., von Knethen, A., Pfeilschifter, J.M., and Brune, B. (2008). Apoptotic cell-derived sphingosine-1-phosphate promotes HuR-dependent cyclooxygenase-2 mRNA stabilization and protein expression. J. Immunol. 180, 1239-1248.
    • (2008) J. Immunol , vol.180 , pp. 1239-1248
    • Johann, A.M.1    Weigert, A.2    Eberhardt, W.3    Kuhn, A.M.4    Barra, V.5    von Knethen, A.6    Pfeilschifter, J.M.7    Brune, B.8
  • 55
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr, J.F., Wyllie, A.H., and Currie, A.R. (1972). Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26, 239-257.
    • (1972) Br. J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 57
    • 33947591498 scopus 로고    scopus 로고
    • Engulfment of apoptotic cells by microvascular endothelial cells induces proinflammatory responses
    • Kirsch, T., Woywodt, A., Beese, M., Wyss, K., Park, J.K., Erdbruegger, U., Hertel, B., Haller, H., and Haubitz, M. (2007). Engulfment of apoptotic cells by microvascular endothelial cells induces proinflammatory responses. Blood 109, 2854-2862.
    • (2007) Blood , vol.109 , pp. 2854-2862
    • Kirsch, T.1    Woywodt, A.2    Beese, M.3    Wyss, K.4    Park, J.K.5    Erdbruegger, U.6    Hertel, B.7    Haller, H.8    Haubitz, M.9
  • 58
    • 30944447092 scopus 로고    scopus 로고
    • Lysophosphatidylcholine and secretory phospholipase A2 in vascular disease: Mediators of endothelial dysfunction and atherosclerosis
    • Kougias, P., Chai, H., Lin, P.H., Lumsden, A.B., Yao, Q., and Chen, C. (2006). Lysophosphatidylcholine and secretory phospholipase A2 in vascular disease: mediators of endothelial dysfunction and atherosclerosis. Med. Sci. Monit. 12, RA5-RA16.
    • (2006) Med. Sci. Monit , vol.12
    • Kougias, P.1    Chai, H.2    Lin, P.H.3    Lumsden, A.B.4    Yao, Q.5    Chen, C.6
  • 60
    • 0027521572 scopus 로고
    • Interleukin-10-deficient mice develop chronic enterocolitis
    • Kuhn, R., Lohler, J., Rennick, D., Rajewsky, K., and Muller, W. (1993). Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75, 263-274.
    • (1993) Cell , vol.75 , pp. 263-274
    • Kuhn, R.1    Lohler, J.2    Rennick, D.3    Rajewsky, K.4    Muller, W.5
  • 61
    • 1542406446 scopus 로고    scopus 로고
    • NOX enzymes and the biology of reactive oxygen
    • Lambeth, J.D. (2004). NOX enzymes and the biology of reactive oxygen. Nat. Rev. Immunol. 4, 181-189.
    • (2004) Nat. Rev. Immunol , vol.4 , pp. 181-189
    • Lambeth, J.D.1
  • 62
    • 0034283687 scopus 로고    scopus 로고
    • Differential requirement for classic and novel PKC isoforms in respiratory burst and phagocytosis in RAW 264.7 cells
    • Larsen, E.C., DiGennaro, J.A., Saito, N., Mehta, S., Loegering, D.J., Mazurkiewicz, J.E., and Lennartz, M.R. (2000). Differential requirement for classic and novel PKC isoforms in respiratory burst and phagocytosis in RAW 264.7 cells. J. Immunol. 165, 2809-2817.
    • (2000) J. Immunol , vol.165 , pp. 2809-2817
    • Larsen, E.C.1    DiGennaro, J.A.2    Saito, N.3    Mehta, S.4    Loegering, D.J.5    Mazurkiewicz, J.E.6    Lennartz, M.R.7
  • 64
    • 2342584674 scopus 로고    scopus 로고
    • Clearance of apoptotic cells: Getting rid of the corpses
    • Lauber, K., Blumenthal, S.G., Waibel, M., and Wesselborg, S. (2004). Clearance of apoptotic cells: getting rid of the corpses. Mol. Cell 14, 277-287.
    • (2004) Mol. Cell , vol.14 , pp. 277-287
    • Lauber, K.1    Blumenthal, S.G.2    Waibel, M.3    Wesselborg, S.4
  • 65
    • 0031944290 scopus 로고    scopus 로고
    • Regulation of immune responses by TGF-β
    • Letterio, J.J. and Roberts, A.B. (1998). Regulation of immune responses by TGF-β. Annu. Rev. Immunol. 16, 137-161.
    • (1998) Annu. Rev. Immunol , vol.16 , pp. 137-161
    • Letterio, J.J.1    Roberts, A.B.2
  • 66
    • 34250214950 scopus 로고    scopus 로고
    • The macrophage at the crossroads of insulin resistance and atherosclerosis
    • Liang, C.P., Han, S., Senokuchi, T., and Tall, A.R. (2007). The macrophage at the crossroads of insulin resistance and atherosclerosis. Circ. Res. 100, 1546-1555.
    • (2007) Circ. Res , vol.100 , pp. 1546-1555
    • Liang, C.P.1    Han, S.2    Senokuchi, T.3    Tall, A.R.4
  • 67
    • 56049106702 scopus 로고    scopus 로고
    • High mobility group protein-1 inhibits phagocytosis of apoptotic neutrophils through binding to phosphatidylserine
    • Liu, G., Wang, J., Park, Y.J., Tsuruta, Y., Lorne, E.F., Zhao, X., and Abraham, E. (2008). High mobility group protein-1 inhibits phagocytosis of apoptotic neutrophils through binding to phosphatidylserine. J. Immunol. 181, 4240-4246.
    • (2008) J. Immunol , vol.181 , pp. 4240-4246
    • Liu, G.1    Wang, J.2    Park, Y.J.3    Tsuruta, Y.4    Lorne, E.F.5    Zhao, X.6    Abraham, E.7
  • 69
    • 0000642969 scopus 로고
    • The immunological basis of acquired cellular resistance
    • Mackaness, G.B. (1964). The immunological basis of acquired cellular resistance. J. Exp. Med. 120, 105-120.
    • (1964) J. Exp. Med , vol.120 , pp. 105-120
    • Mackaness, G.B.1
  • 70
    • 3142644996 scopus 로고    scopus 로고
    • Tumour-associated macrophages as a prototypic type II polarised phagocyte population: Role in tumour progression
    • Mantovani, A., Allavena, P., and Sica, A. (2004a). Tumour-associated macrophages as a prototypic type II polarised phagocyte population: role in tumour progression. Eur. J. Cancer 40, 1660-1667.
    • (2004) Eur. J. Cancer , vol.40 , pp. 1660-1667
    • Mantovani, A.1    Allavena, P.2    Sica, A.3
  • 71
    • 7644231561 scopus 로고    scopus 로고
    • The chemokine system in diverse forms of macrophage activation and polarization
    • Mantovani, A., Sica, A., Sozzani, S., Allavena, P., Vecchi, A., and Locati, M. (2004b). The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol. 25, 677-686.
    • (2004) Trends Immunol , vol.25 , pp. 677-686
    • Mantovani, A.1    Sica, A.2    Sozzani, S.3    Allavena, P.4    Vecchi, A.5    Locati, M.6
  • 72
    • 0028800947 scopus 로고
    • Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl
    • Martin, S.J., Reutelingsperger, C.P., McGahon, A.J., Rader, J.A., van Schie, R.C., LaFace, D.M., and Green, D.R. (1995). Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl. J. Exp. Med. 182, 1545-1556.
    • (1995) J. Exp. Med , vol.182 , pp. 1545-1556
    • Martin, S.J.1    Reutelingsperger, C.P.2    McGahon, A.J.3    Rader, J.A.4    van Schie, R.C.5    LaFace, D.M.6    Green, D.R.7
  • 73
    • 60549103394 scopus 로고    scopus 로고
    • Efferocytosis impairs pulmonary macrophage and lung antibacterial function via PGE2/EP2 signaling
    • Medeiros, A.I., Serezani, C.H., Lee, S.P., and Peters-Golden, M. (2009). Efferocytosis impairs pulmonary macrophage and lung antibacterial function via PGE2/EP2 signaling. J. Exp. Med. 206, 61-68.
    • (2009) J. Exp. Med , vol.206 , pp. 61-68
    • Medeiros, A.I.1    Serezani, C.H.2    Lee, S.P.3    Peters-Golden, M.4
  • 74
    • 33847361903 scopus 로고    scopus 로고
    • Infectious disease, the innate immune response, and fibrosis
    • Meneghin, A. and Hogaboam, C.M. (2007). Infectious disease, the innate immune response, and fibrosis. J. Clin. Invest. 117, 530-538.
    • (2007) J. Clin. Invest , vol.117 , pp. 530-538
    • Meneghin, A.1    Hogaboam, C.M.2
  • 76
    • 61449243725 scopus 로고    scopus 로고
    • Macrophage phagocytosis of apoptotic neutrophils is critically regulated by the opposing actions of pro-inflammatory and anti-inflammatory agents: Key role for TNFα
    • Michlewska, S., Dransfield, I., Megson, I.L., and Rossi, A.G. (2009). Macrophage phagocytosis of apoptotic neutrophils is critically regulated by the opposing actions of pro-inflammatory and anti-inflammatory agents: key role for TNFα. FASEB J. 23, 844-854.
    • (2009) FASEB J , vol.23 , pp. 844-854
    • Michlewska, S.1    Dransfield, I.2    Megson, I.L.3    Rossi, A.G.4
  • 79
    • 0345237926 scopus 로고    scopus 로고
    • Macrophage recognition and phagocytosis of apoptotic fibroblasts is critically dependent on fibroblast-derived thrombospondin 1 and CD36
    • Moodley, Y., Rigby, P., Bundell, C., Bunt, S., Hayashi, H., Misso, N., McAnulty, R., Laurent, G., Scaffidi, A., Thompson, P., et al. (2003). Macrophage recognition and phagocytosis of apoptotic fibroblasts is critically dependent on fibroblast-derived thrombospondin 1 and CD36. Am. J. Pathol. 162, 771-779.
    • (2003) Am. J. Pathol , vol.162 , pp. 771-779
    • Moodley, Y.1    Rigby, P.2    Bundell, C.3    Bunt, S.4    Hayashi, H.5    Misso, N.6    McAnulty, R.7    Laurent, G.8    Scaffidi, A.9    Thompson, P.10
  • 81
    • 4744355192 scopus 로고    scopus 로고
    • Enzymes of arginine metabolism
    • discussion 2765S-2767S
    • Morris, S.M. Jr. (2004). Enzymes of arginine metabolism. J. Nutr. 134, 2743S-2747S; discussion 2765S-2767S.
    • (2004) J. Nutr , vol.134
    • Morris Jr., S.M.1
  • 82
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser, D.M. and Edwards, J.P. (2008). Exploring the full spectrum of macrophage activation. Nat. Rev. Immunol. 8, 958-969.
    • (2008) Nat. Rev. Immunol , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 83
    • 34249818786 scopus 로고    scopus 로고
    • Attraction of phagocytes by apoptotic cells is mediated by lysophosphatidylcholine
    • Mueller, R.B., Sheriff, A., Gaipl, U.S., Wesselborg, S., and Lauber, K. (2007). Attraction of phagocytes by apoptotic cells is mediated by lysophosphatidylcholine. Autoimmunity 40, 342-344.
    • (2007) Autoimmunity , vol.40 , pp. 342-344
    • Mueller, R.B.1    Sheriff, A.2    Gaipl, U.S.3    Wesselborg, S.4    Lauber, K.5
  • 85
    • 0036320896 scopus 로고    scopus 로고
    • Phagocytosis of apoptotic cells by macrophages from NOD mice is reduced
    • O'Brien, B.A., Huang, Y., Geng, X., Dutz, J.P., and Finegood, D.T. (2002). Phagocytosis of apoptotic cells by macrophages from NOD mice is reduced. Diabetes 51, 2481-2488.
    • (2002) Diabetes , vol.51 , pp. 2481-2488
    • O'Brien, B.A.1    Huang, Y.2    Geng, X.3    Dutz, J.P.4    Finegood, D.T.5
  • 86
    • 41549107522 scopus 로고    scopus 로고
    • Cytokine signaling modules in inflammatory responses
    • O'Shea, J.J. and Murray, P.J. (2008). Cytokine signaling modules in inflammatory responses. Immunity 28, 477-487.
    • (2008) Immunity , vol.28 , pp. 477-487
    • O'Shea, J.J.1    Murray, P.J.2
  • 87
    • 0038393112 scopus 로고    scopus 로고
    • Apoptosis in the development and maintenance of the immune system
    • Opferman, J.T. and Korsmeyer, S.J. (2003). Apoptosis in the development and maintenance of the immune system. Nat. Immunol. 4, 410-415.
    • (2003) Nat. Immunol , vol.4 , pp. 410-415
    • Opferman, J.T.1    Korsmeyer, S.J.2
  • 93
    • 0029960471 scopus 로고    scopus 로고
    • Role for the class A macrophage scavenger receptor in the phagocytosis of apoptotic thymocytes in vitro
    • Platt, N., Suzuki, H., Kurihara, Y., Kodama, T., and Gordon, S. (1996). Role for the class A macrophage scavenger receptor in the phagocytosis of apoptotic thymocytes in vitro. Proc. Natl. Acad. Sci. USA 93, 12456-12460.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 12456-12460
    • Platt, N.1    Suzuki, H.2    Kurihara, Y.3    Kodama, T.4    Gordon, S.5
  • 94
    • 36448961645 scopus 로고    scopus 로고
    • Engulfment of apoptotic cells: Signals for a good meal
    • Ravichandran, K.S. and Lorenz, U. (2007). Engulfment of apoptotic cells: signals for a good meal. Nat. Rev. Immunol. 7, 964-974.
    • (2007) Nat. Rev. Immunol , vol.7 , pp. 964-974
    • Ravichandran, K.S.1    Lorenz, U.2
  • 95
    • 0033566932 scopus 로고    scopus 로고
    • Cutting edge: Differential effect of apoptotic versus necrotic tumor cells on macrophage antitumor activities
    • Reiter, I., Krammer, B., and Schwamberger, G. (1999). Cutting edge: differential effect of apoptotic versus necrotic tumor cells on macrophage antitumor activities. J. Immunol. 163, 1730-1732.
    • (1999) J. Immunol , vol.163 , pp. 1730-1732
    • Reiter, I.1    Krammer, B.2    Schwamberger, G.3
  • 96
    • 34547603895 scopus 로고    scopus 로고
    • PPARs and molecular mechanisms of transrepression
    • Ricote, M. and Glass, C.K. (2007). PPARs and molecular mechanisms of transrepression. Biochim. Biophys. Acta 1771, 926-935.
    • (2007) Biochim. Biophys. Acta , vol.1771 , pp. 926-935
    • Ricote, M.1    Glass, C.K.2
  • 97
    • 33845752914 scopus 로고    scopus 로고
    • p50 nuclear factor-κB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance
    • Saccani, A., Schioppa, T., Porta, C., Biswas, S.K., Nebuloni, M., Vago, L., Bottazzi, B., Colombo, M.P., Mantovani, A., and Sica, A. (2006). p50 nuclear factor-κB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance. Cancer Res. 66, 11432-11440.
    • (2006) Cancer Res , vol.66 , pp. 11432-11440
    • Saccani, A.1    Schioppa, T.2    Porta, C.3    Biswas, S.K.4    Nebuloni, M.5    Vago, L.6    Bottazzi, B.7    Colombo, M.P.8    Mantovani, A.9    Sica, A.10
  • 98
    • 0034641931 scopus 로고    scopus 로고
    • Corpse clearance defines the meaning of cell death
    • Savill, J. and Fadok, V. (2000). Corpse clearance defines the meaning of cell death. Nature 407, 784-788.
    • (2000) Nature , vol.407 , pp. 784-788
    • Savill, J.1    Fadok, V.2
  • 99
    • 0024536234 scopus 로고
    • Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages
    • Savill, J.S., Wyllie, A.H., Henson, J.E., Walport, M.J., Henson, P.M., and Haslett, C. (1989). Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages. J. Clin. Invest. 83, 865-875.
    • (1989) J. Clin. Invest , vol.83 , pp. 865-875
    • Savill, J.S.1    Wyllie, A.H.2    Henson, J.E.3    Walport, M.J.4    Henson, P.M.5    Haslett, C.6
  • 100
    • 0036884424 scopus 로고    scopus 로고
    • A blast from the past: Clearance of apoptotic cells regulates immune responses
    • Savill, J., Dransfield, I., Gregory, C., and Haslett, C. (2002). A blast from the past: clearance of apoptotic cells regulates immune responses. Nat. Rev. Immunol. 2, 965-975.
    • (2002) Nat. Rev. Immunol , vol.2 , pp. 965-975
    • Savill, J.1    Dransfield, I.2    Gregory, C.3    Haslett, C.4
  • 101
    • 47749139256 scopus 로고    scopus 로고
    • Cancer as an overhealing wound: An old hypothesis revisited
    • Schafer, M. and Werner, S. (2008). Cancer as an overhealing wound: an old hypothesis revisited. Nat. Rev. Mol. Cell Biol. 9, 628-638.
    • (2008) Nat. Rev. Mol. Cell Biol , vol.9 , pp. 628-638
    • Schafer, M.1    Werner, S.2
  • 104
    • 30044449982 scopus 로고    scopus 로고
    • Resolution of inflammation: The beginning programs the end
    • Serhan, C.N. and Savill, J. (2005). Resolution of inflammation: the beginning programs the end. Nat. Immunol. 6, 1191-1197.
    • (2005) Nat. Immunol , vol.6 , pp. 1191-1197
    • Serhan, C.N.1    Savill, J.2
  • 105
    • 23044481743 scopus 로고    scopus 로고
    • Apoptotic cells quench reactive oxygen and nitrogen species and modulate TNF-α/TGF-β1 balance in activated macrophages: Involvement of phosphatidylserine-dependent and -independent pathways
    • Serinkan, B.F., Gambelli, F., Potapovich, A.I., Babu, H., Di Giuseppe, M., Ortiz, L.A., Fabisiak, J.P., and Kagan, V.E. (2005). Apoptotic cells quench reactive oxygen and nitrogen species and modulate TNF-α/TGF-β1 balance in activated macrophages: involvement of phosphatidylserine-dependent and -independent pathways. Cell Death Differ. 12, 1141-1144.
    • (2005) Cell Death Differ , vol.12 , pp. 1141-1144
    • Serinkan, B.F.1    Gambelli, F.2    Potapovich, A.I.3    Babu, H.4    Di Giuseppe, M.5    Ortiz, L.A.6    Fabisiak, J.P.7    Kagan, V.E.8
  • 106
    • 0034650833 scopus 로고    scopus 로고
    • Autocrine production of IL-10 mediates defective IL-12 production and NF-κB activation in tumor-associated macrophages
    • Sica, A., Saccani, A., Bottazzi, B., Polentarutti, N., Vecchi, A., van Damme, J., and Mantovani, A. (2000). Autocrine production of IL-10 mediates defective IL-12 production and NF-κB activation in tumor-associated macrophages. J. Immunol. 164, 762-767.
    • (2000) J. Immunol , vol.164 , pp. 762-767
    • Sica, A.1    Saccani, A.2    Bottazzi, B.3    Polentarutti, N.4    Vecchi, A.5    van Damme, J.6    Mantovani, A.7
  • 108
    • 0028109394 scopus 로고
    • Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal macrophages by prostaglandin E2
    • Strassmann, G., Patil-Koota, V., Finkelman, F., Fong, M., and Kambayashi, T. (1994). Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal macrophages by prostaglandin E2. J. Exp. Med. 180, 2365-2370.
    • (1994) J. Exp. Med , vol.180 , pp. 2365-2370
    • Strassmann, G.1    Patil-Koota, V.2    Finkelman, F.3    Fong, M.4    Kambayashi, T.5
  • 109
    • 19344363325 scopus 로고    scopus 로고
    • Phagocytosis: Elegant complexity
    • Stuart, L.M. and Ezekowitz, R.A. (2005). Phagocytosis: elegant complexity. Immunity 22, 539-550.
    • (2005) Immunity , vol.22 , pp. 539-550
    • Stuart, L.M.1    Ezekowitz, R.A.2
  • 111
    • 32344435015 scopus 로고    scopus 로고
    • The immunoregulatory role of IDO-producing human dendritic cells revisited
    • Terness, P., Chuang, J.J., and Opelz, G. (2006). The immunoregulatory role of IDO-producing human dendritic cells revisited. Trends Immunol. 27, 68-73.
    • (2006) Trends Immunol , vol.27 , pp. 68-73
    • Terness, P.1    Chuang, J.J.2    Opelz, G.3
  • 112
    • 41249092199 scopus 로고    scopus 로고
    • Autophosphorylation docking site Tyr-867 in Mer receptor tyrosine kinase allows for dissociation of multiple signaling pathways for phagocytosis of apoptotic cells and down-modulation of lipopolysaccha- ride-inducible NF-κB transcriptional activation
    • Tibrewal, N., Wu, Y., D'Mello, V., Akakura, R., George, T.C., Varnum, B., and Birge, R.B. (2008). Autophosphorylation docking site Tyr-867 in Mer receptor tyrosine kinase allows for dissociation of multiple signaling pathways for phagocytosis of apoptotic cells and down-modulation of lipopolysaccha- ride-inducible NF-κB transcriptional activation. J. Biol. Chem. 283, 3618-3627.
    • (2008) J. Biol. Chem , vol.283 , pp. 3618-3627
    • Tibrewal, N.1    Wu, Y.2    D'Mello, V.3    Akakura, R.4    George, T.C.5    Varnum, B.6    Birge, R.B.7
  • 113
    • 33745121896 scopus 로고    scopus 로고
    • Burying the dead: The impact of failed apoptotic cell removal (efferocytosis) on chronic inflammatory lung disease
    • Vandivier, R.W., Henson, P.M., and Douglas, I.S. (2006). Burying the dead: the impact of failed apoptotic cell removal (efferocytosis) on chronic inflammatory lung disease. Chest 129, 1673-1682.
    • (2006) Chest , vol.129 , pp. 1673-1682
    • Vandivier, R.W.1    Henson, P.M.2    Douglas, I.S.3
  • 114
    • 0028820202 scopus 로고
    • Mechanisms of phosphatidylserine exposure, a phagocyte recognition signal, on apoptotic T lymphocytes
    • Verhoven, B., Schlegel, R.A., and Williamson, P. (1995). Mechanisms of phosphatidylserine exposure, a phagocyte recognition signal, on apoptotic T lymphocytes. J. Exp. Med. 182, 1597-1601.
    • (1995) J. Exp. Med , vol.182 , pp. 1597-1601
    • Verhoven, B.1    Schlegel, R.A.2    Williamson, P.3
  • 115
    • 33644830810 scopus 로고    scopus 로고
    • Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages
    • Visentin, B., Vekich, J.A., Sibbald, B.J., Cavalli, A.L., Moreno, K.M., Matteo, R.G., Garland, W.A., Lu, Y., Yu, S., Hall, H.S., et al. (2006). Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages. Cancer Cell 9, 225-238.
    • (2006) Cancer Cell , vol.9 , pp. 225-238
    • Visentin, B.1    Vekich, J.A.2    Sibbald, B.J.3    Cavalli, A.L.4    Moreno, K.M.5    Matteo, R.G.6    Garland, W.A.7    Lu, Y.8    Yu, S.9    Hall, H.S.10
  • 116
    • 0031454570 scopus 로고    scopus 로고
    • Voll, R.E.,w Herrmann, M., Roth, E.A., Stach, C., Kalden, J.R., and Girkontaite, I. (1997). Immunosuppressive effects of apoptotic cells. Nature 390, 350-351.
    • Voll, R.E.,w Herrmann, M., Roth, E.A., Stach, C., Kalden, J.R., and Girkontaite, I. (1997). Immunosuppressive effects of apoptotic cells. Nature 390, 350-351.
  • 118
    • 0033515887 scopus 로고    scopus 로고
    • Two distinct cytokines released from a human aminoacyl-tRNA synthetase
    • Wakasugi, K. and Schimmel, P. (1999). Two distinct cytokines released from a human aminoacyl-tRNA synthetase. Science 284, 147-151.
    • (1999) Science , vol.284 , pp. 147-151
    • Wakasugi, K.1    Schimmel, P.2
  • 119
    • 33748178875 scopus 로고    scopus 로고
    • Apoptotic cells promote macrophage survival by releasing the antiapoptotic mediator sphingosine-1-phosphate
    • Weigert, A., Johann, A.M., von Knethen, A., Schmidt, H., Geisslinger, G., and Brune, B. (2006). Apoptotic cells promote macrophage survival by releasing the antiapoptotic mediator sphingosine-1-phosphate. Blood 108, 1635-1642.
    • (2006) Blood , vol.108 , pp. 1635-1642
    • Weigert, A.1    Johann, A.M.2    von Knethen, A.3    Schmidt, H.4    Geisslinger, G.5    Brune, B.6
  • 121
    • 67649609064 scopus 로고    scopus 로고
    • Tumor-associated macrophages as targets for tumor immunotherapy
    • Weigert, A., Sekar, D., and Brüne, B. (2009). Tumor-associated macrophages as targets for tumor immunotherapy. Immunotherapy 1, 83-95.
    • (2009) Immunotherapy , vol.1 , pp. 83-95
    • Weigert, A.1    Sekar, D.2    Brüne, B.3
  • 122
    • 65249113865 scopus 로고    scopus 로고
    • Heme oxygenase-1 contributes to an alternative macrophage activation profile induced by apoptotic cell supernatants
    • Weis, N., Weigert, A., von Knethen, A., and Brune, B. (2009). Heme oxygenase-1 contributes to an alternative macrophage activation profile induced by apoptotic cell supernatants. Mol. Biol. Cell 20, 1280-1288.
    • (2009) Mol. Biol. Cell , vol.20 , pp. 1280-1288
    • Weis, N.1    Weigert, A.2    von Knethen, A.3    Brune, B.4
  • 123
    • 33645845142 scopus 로고    scopus 로고
    • Phosphatidylserine recognition by phagocytes: A view to a kill
    • Wu, Y., Tibrewal, N., and Birge, R.B. (2006). Phosphatidylserine recognition by phagocytes: a view to a kill. Trends Cell Biol. 16, 189-197.
    • (2006) Trends Cell Biol , vol.16 , pp. 189-197
    • Wu, Y.1    Tibrewal, N.2    Birge, R.B.3
  • 124
    • 0019225636 scopus 로고
    • Cell death: The significance of apoptosis
    • Wyllie, A.H., Kerr, J.F., and Currie, A.R. (1980). Cell death: the significance of apoptosis. Int. Rev. Cytol. 68, 251-306.
    • (1980) Int. Rev. Cytol , vol.68 , pp. 251-306
    • Wyllie, A.H.1    Kerr, J.F.2    Currie, A.R.3
  • 125
    • 33847350691 scopus 로고    scopus 로고
    • Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases
    • Wynn, T.A. (2007). Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases. J. Clin. Invest. 117, 524-529.
    • (2007) J. Clin. Invest , vol.117 , pp. 524-529
    • Wynn, T.A.1
  • 126
    • 38549159026 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of fibrosis
    • Wynn, T.A. (2008). Cellular and molecular mechanisms of fibrosis. J. Pathol. 214, 199-210.
    • (2008) J. Pathol , vol.214 , pp. 199-210
    • Wynn, T.A.1
  • 127
    • 51549110623 scopus 로고    scopus 로고
    • Transcriptional and translational regulation of TGF-β production in response to apoptotic cells
    • Xiao, Y.Q., Freire-de-Lima, C.G., Schiemann, W.P., Bratton, D.L., Vandivier, R.W., and Henson, P.M. (2008). Transcriptional and translational regulation of TGF-β production in response to apoptotic cells. J. Immunol. 181, 3575-3585.
    • (2008) J. Immunol , vol.181 , pp. 3575-3585
    • Xiao, Y.Q.1    Freire-de-Lima, C.G.2    Schiemann, W.P.3    Bratton, D.L.4    Vandivier, R.W.5    Henson, P.M.6
  • 128
    • 4143092587 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate cross-activates the Smad signaling cascade and mimics transforming growth factor-β-induced cell responses
    • Xin, C., Ren, S., Kleuser, B., Shabahang, S., Eberhardt, W., Radeke, H., Schafer-Korting, M., Pfeilschifter, J., and Huwiler, A. (2004). Sphingosine 1-phosphate cross-activates the Smad signaling cascade and mimics transforming growth factor-β-induced cell responses. J. Biol. Chem. 279, 35255-35262.
    • (2004) J. Biol. Chem , vol.279 , pp. 35255-35262
    • Xin, C.1    Ren, S.2    Kleuser, B.3    Shabahang, S.4    Eberhardt, W.5    Radeke, H.6    Schafer-Korting, M.7    Pfeilschifter, J.8    Huwiler, A.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.