-
1
-
-
33645739790
-
Tumor stroma and regulation of cancer development
-
Tlsty TD, Coussens LM: Tumor stroma and regulation of cancer development. Annu. Rev. Pathol. 1, 119-150 (2006).
-
(2006)
Annu. Rev. Pathol.
, vol.1
, pp. 119-150
-
-
Tlsty, T.D.1
Coussens, L.M.2
-
2
-
-
9444260942
-
Tumor cells escape suicide gene therapy by genetic and epigenetic instability
-
DOI 10.1182/blood-2004-03-0852
-
Frank O, Rudolph C, Heberlein C et al.: Tumor cells escape suicide gene therapy by genetic and epigenetic instability. Blood 104(12), 3543-3549 (2004). (Pubitemid 39564425)
-
(2004)
Blood
, vol.104
, Issue.12
, pp. 3543-3549
-
-
Frank, O.1
Rudolph, C.2
Heberlein, C.3
Von Neuhoff, N.4
Schrock, E.5
Schambach, A.6
Schlegelberger, B.7
Fehse, B.8
Ostertag, W.9
Stocking, C.10
Baum, C.11
-
5
-
-
16244408626
-
Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy
-
Muller AJ, DuHadaway JB, Donover PS, Sutanto-Ward E, Prendergast GC: Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy. Nat. Med. 11(3), 312-319 (2005).
-
(2005)
Nat. Med.
, vol.11
, Issue.3
, pp. 312-319
-
-
Muller, A.J.1
Duhadaway, J.B.2
Donover, P.S.3
Sutanto-Ward, E.4
Prendergast, G.C.5
-
6
-
-
11844277698
-
Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease
-
Sinha P, Clements VK, Ostrand-Rosenberg S: Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease. J. Immunol. 174(2), 636-645 (2005). (Pubitemid 40094255)
-
(2005)
Journal of Immunology
, vol.174
, Issue.2
, pp. 636-645
-
-
Sinha, P.1
Clements, V.K.2
Ostrand-Rosenberg, S.3
-
7
-
-
45549092607
-
Cancer immunology
-
Finn OJ: Cancer immunology. N. Engl. J. Med. 358(25), 2704-2715 (2008).
-
(2008)
N. Engl. J. Med.
, vol.358
, Issue.25
, pp. 2704-2715
-
-
Finn, O.J.1
-
8
-
-
20444436860
-
Cancer immunotherapy comes of age
-
Rosenberg SA: Cancer immunotherapy comes of age. Nat. Clin. Pract. Oncol. 2(3), 115 (2005).
-
(2005)
Nat. Clin. Pract. Oncol.
, vol.2
, Issue.3
, pp. 115
-
-
Rosenberg, S.A.1
-
9
-
-
0038307824
-
Immunotherapy as part of combinations for the treatment of cancer
-
Mitchell MS: Immunotherapy as part of combinations for the treatment of cancer. Int. Immunopharmacol. 3(8), 1051-1059 (2003).
-
(2003)
Int. Immunopharmacol.
, vol.3
, Issue.8
, pp. 1051-1059
-
-
Mitchell, M.S.1
-
10
-
-
33745946911
-
Therapeutic potential of Toll-like receptor 9 activation
-
Krieg AM: Therapeutic potential of Toll-like receptor 9 activation. Nat. Rev. Drug Discov. 5(6), 471-484 (2006).
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, Issue.6
, pp. 471-484
-
-
Krieg, A.M.1
-
11
-
-
0030026776
-
Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells
-
Hsu FJ, Benike C, Fagnoni F et al.: Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells. Nat. Med. 2(1), 52-58 (1996).
-
(1996)
Nat. Med.
, vol.2
, Issue.1
, pp. 52-58
-
-
Hsu, F.J.1
Benike, C.2
Fagnoni, F.3
-
12
-
-
2342485077
-
Bystander elimination of antigen loss variants in established tumors
-
Demonstrates clearly the involvement of the tumor stroma in presentation of tumor antigens and the importance to target it in antitumor therapy
-
Spiotto MT, Rowley DA, Schreiber H: Bystander elimination of antigen loss variants in established tumors. Nat. Med. 10(3), 294-298 (2004). ■■ Demonstrates clearly the involvement of the tumor stroma in presentation of tumor antigens and the importance to target it in antitumor therapy.
-
(2004)
Nat. Med.
, vol.10
, Issue.3
, pp. 294-298
-
-
Spiotto, M.T.1
Rowley, D.A.2
Schreiber, H.3
-
13
-
-
0037415596
-
Immunotherapy of cytotoxic TB lymphocyte-resistant tumors by T helper 2 cells: An eotaxin and STAT6-dependent process
-
Mattes J, Hulett M, Xie W et al.: Immunotherapy of cytotoxic TB lymphocyte-resistant tumors by T helper 2 cells: an eotaxin and STAT6-dependent process. J. Exp. Med. 197(3), 387-393 (2003).
-
(2003)
J. Exp. Med.
, vol.197
, Issue.3
, pp. 387-393
-
-
Mattes, J.1
Hulett, M.2
Xie, W.3
-
14
-
-
0033662405
-
+ T-cell mediated tumor rejection involves inhibition of angiogenesis that is dependent on IFNγ receptor expression by nonhematopoietic cells
-
+ T-cell mediated tumor rejection involves inhibition of angiogenesis that is dependent on IFNγ receptor expression by nonhematopoietic cells. Immunity 12(6), 677-686 (2000).
-
(2000)
Immunity
, vol.12
, Issue.6
, pp. 677-686
-
-
Qin, Z.1
Blankenstein, T.2
-
16
-
-
0029394825
-
The macrophage
-
Gordon S: The macrophage. Bioessays 17(11), 977-986 (1995).
-
(1995)
Bioessays
, vol.17
, Issue.11
, pp. 977-986
-
-
Gordon, S.1
-
17
-
-
21244443731
-
Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences
-
Stout RD, Jiang C, Matta B, Tietzel I, Watkins SK, Suttles J: Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences. J. Immunol. 175(1), 342-349 (2005). (Pubitemid 40884337)
-
(2005)
Journal of Immunology
, vol.175
, Issue.1
, pp. 342-349
-
-
Stout, R.D.1
Jiang, C.2
Matta, B.3
Tietzel, I.4
Watkins, S.K.5
Suttles, J.6
-
18
-
-
0037281863
-
The inflammatory macrophage: A story of Jekyll and Hyde
-
Duffield JS: The inflammatory macrophage: a story of Jekyll and Hyde. Clin. Sci. (Lond.) 104(1), 27-38 (2003).
-
(2003)
Clin. Sci. (Lond.)
, vol.104
, Issue.1
, pp. 27-38
-
-
Duffield, J.S.1
-
19
-
-
0037265240
-
Alternative activation of macrophages
-
Important review helping in understanding macrophage biology
-
Gordon S: Alternative activation of macrophages. Nat. Rev. Immunol. 3(1), 23-35 (2003). ■ Important review helping in understanding macrophage biology.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, Issue.1
, pp. 23-35
-
-
Gordon, S.1
-
20
-
-
34250214950
-
The macrophage at the crossroads of insulin resistance and atherosclerosis
-
Liang CP, Han S, Senokuchi T, Tall AR: The macrophage at the crossroads of insulin resistance and atherosclerosis. Circ. Res. 100(11), 1546-1555 (2007).
-
(2007)
Circ. Res.
, vol.100
, Issue.11
, pp. 1546-1555
-
-
Liang, C.P.1
Han, S.2
Senokuchi, T.3
Tall, A.R.4
-
21
-
-
33645991795
-
Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy
-
Sica A, Schioppa T, Mantovani A, Allavena P: Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy. Eur. J. Cancer 42(6), 717-727 (2006).
-
(2006)
Eur. J. Cancer
, vol.42
, Issue.6
, pp. 717-727
-
-
Sica, A.1
Schioppa, T.2
Mantovani, A.3
Allavena, P.4
-
22
-
-
0023147156
-
Secretory products of macrophages
-
Nathan CF: Secretory products of macrophages. J. Clin. Invest. 79(2), 319-326 (1987).
-
(1987)
J. Clin. Invest.
, vol.79
, Issue.2
, pp. 319-326
-
-
Nathan, C.F.1
-
23
-
-
7644231561
-
The chemokine system in diverse forms of macrophage activation and polarization
-
DOI 10.1016/j.it.2004.09.015, PII S1471490604002959
-
Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, Locati M: The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol. 25(12), 677-686 (2004). (Pubitemid 39457982)
-
(2004)
Trends in Immunology
, vol.25
, Issue.12
, pp. 677-686
-
-
Mantovani, A.1
Sica, A.2
Sozzani, S.3
Allavena, P.4
Vecchi, A.5
Locati, M.6
-
24
-
-
0036839143
-
Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
-
DOI 10.1016/S1471-4906(02)02302-5, PII S1471490602023025
-
Mantovani A, Sozzani S, Locati M, Allavena P, Sica A: Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol. 23(11), 549-555 (2002). (Pubitemid 35223554)
-
(2002)
Trends in Immunology
, vol.23
, Issue.11
, pp. 549-555
-
-
Mantovani, A.1
Sozzani, S.2
Locati, M.3
Allavena, P.4
Sica, A.5
-
25
-
-
0344393516
-
Regulation of macrophage activation
-
Ma J, Chen T, Mandelin J et al.: Regulation of macrophage activation. Cell. Mol. Life Sci. 60(11), 2334-2346 (2003).
-
(2003)
Cell. Mol. Life Sci.
, vol.60
, Issue.11
, pp. 2334-2346
-
-
Ma, J.1
Chen, T.2
Mandelin, J.3
-
26
-
-
0037310024
-
The many faces of macrophage activation
-
Mosser DM: The many faces of macrophage activation. J. Leukoc. Biol. 73(2), 209-212 (2003).
-
(2003)
J. Leukoc. Biol.
, vol.73
, Issue.2
, pp. 209-212
-
-
Mosser, D.M.1
-
27
-
-
22544480574
-
Phagocytosis of apoptotic cells: A matter of balance
-
de Almeida CJ, Linden R: Phagocytosis of apoptotic cells: a matter of balance. Cell. Mol. Life Sci. 62(14), 1532-1546 (2005).
-
(2005)
Cell. Mol. Life Sci.
, vol.62
, Issue.14
, pp. 1532-1546
-
-
De Almeida, C.J.1
Linden, R.2
-
28
-
-
2342584674
-
Clearance of apoptotic cells: Getting rid of the corpses
-
DOI 10.1016/S1097-2765(04)00237-0, PII S1097276504002370
-
Lauber K, Blumenthal SG, Waibel M, Wesselborg S: Clearance of apoptotic cells: getting rid of the corpses. Mol. Cell 14(3), 277-287 (2004). (Pubitemid 38607340)
-
(2004)
Molecular Cell
, vol.14
, Issue.3
, pp. 277-287
-
-
Lauber, K.1
Blumenthal, S.G.2
Waibel, M.3
Wesselborg, S.4
-
29
-
-
0034659784
-
M-1/M-2 macrophages and the Th1/Th2 paradigm
-
Mills CD, Kincaid K, Alt JM, Heilman MJ, Hill AM: M-1/M-2 macrophages and the Th1/Th2 paradigm. J. Immunol. 164(12), 6166-6173 (2000).
-
(2000)
J. Immunol.
, vol.164
, Issue.12
, pp. 6166-6173
-
-
Mills, C.D.1
Kincaid, K.2
Alt, J.M.3
Heilman, M.J.4
Hill, A.M.5
-
30
-
-
33745938947
-
Identification of a common gene signature for type II cytokine-associated myeloid cells elicited in vivo in different pathologic conditions
-
DOI 10.1182/blood-2005-04-1485
-
Ghassabeh GH, De Baetselier P, Brys L et al.: Identification of a common gene signature for type II cytokine-associated myeloid cells elicited in vivo in different pathologic conditions. Blood 108(2), 575-583 (2006). ■ Revealed a common genetic signature of murine M2 macrophages. (Pubitemid 44061358)
-
(2006)
Blood
, vol.108
, Issue.2
, pp. 575-583
-
-
Ghassabeh, G.H.1
De Baetselier, P.2
Brys, L.3
Noel, W.4
Van Ginderachter, J.A.5
Meerschaut, S.6
Beschin, A.7
Brombacher, F.8
Raes, G.9
-
31
-
-
1342303482
-
Of Mice and Not Men: Differences between Mouse and Human Immunology
-
Mestas J, Hughes CC: Of mice and not men: differences between mouse and human immunology. J. Immunol. 172(5), 2731-2738 (2004). ■ Highlights important differences between murine and human immunology. (Pubitemid 38263654)
-
(2004)
Journal of Immunology
, vol.172
, Issue.5
, pp. 2731-2738
-
-
Mestas, J.1
Hughes, C.C.W.2
-
32
-
-
18944375453
-
Arginase-1 and Ym1 are markers for murine, but not human, alternatively activated myeloid cells [1] (multiple letters)
-
Raes G, Van den Bergh R, De Baetselier P et al.: Arginase-1 and Ym1 are markers for murine, but not human, alternatively activated myeloid cells. J. Immunol. 174(11), 6561; author reply 6561-6562 (2005). (Pubitemid 40705613)
-
(2005)
Journal of Immunology
, vol.174
, Issue.11
, pp. 6561-6562
-
-
Raes, G.1
Van Den Bergh, R.2
De Baetselier, P.3
Ghassabeh, G.H.4
Scotton, C.5
Locati, M.6
Mantovani, A.7
Sozzani, S.8
-
33
-
-
4944244259
-
Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues
-
DOI 10.1182/blood-2004-03-1109
-
Murdoch C, Giannoudis A, Lewis CE: Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues. Blood 104(8), 2224-2234 (2004). (Pubitemid 39331817)
-
(2004)
Blood
, vol.104
, Issue.8
, pp. 2224-2234
-
-
Murdoch, C.1
Giannoudis, A.2
Lewis, C.E.3
-
34
-
-
0036187615
-
The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
-
DOI 10.1002/path.1027
-
Bingle L, Brown NJ, Lewis CE: The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J. Pathol. 196(3), 254-265 (2002). (Pubitemid 34189413)
-
(2002)
Journal of Pathology
, vol.196
, Issue.3
, pp. 254-265
-
-
Bingle, L.1
Brown, N.J.2
Lewis, C.E.3
-
35
-
-
31544441610
-
Distinct role of macrophages in different tumor microenvironments
-
Lewis CE, Pollard JW: Distinct role of macrophages in different tumor microenvironments. Cancer Res. 66(2), 605-612 (2006).
-
(2006)
Cancer Res.
, vol.66
, Issue.2
, pp. 605-612
-
-
Lewis, C.E.1
Pollard, J.W.2
-
36
-
-
41149164902
-
The yin-yang of tumor-associated macrophages in neoplastic progression and immune surveillance
-
Allavena P, Sica A, Garlanda C, Mantovani A: The yin-yang of tumor-associated macrophages in neoplastic progression and immune surveillance. Immunol. Rev 222, 155-161 (2008).
-
(2008)
Immunol. Rev
, vol.222
, pp. 155-161
-
-
Allavena, P.1
Sica, A.2
Garlanda, C.3
Mantovani, A.4
-
37
-
-
34447327216
-
Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production
-
DOI 10.1126/science.1140485
-
Naugler WE, Sakurai T, Kim S et al.: Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production. Science 317(5834), 121-124 (2007). (Pubitemid 47056470)
-
(2007)
Science
, vol.317
, Issue.5834
, pp. 121-124
-
-
Naugler, W.E.1
Sakurai, T.2
Kim, S.3
Maeda, S.4
Kim, K.5
Elsharkawy, A.M.6
Karin, M.7
-
38
-
-
32044448683
-
Macrophage/cancer cell interactions mediate hormone resistance by a nuclear receptor derepression pathway
-
DOI 10.1016/j.cell.2005.12.032, PII S0092867406000067
-
Zhu P, Baek SH, Bourk EM et al.: Macrophage/cancer cell interactions mediate hormone resistance by a nuclear receptor derepression pathway. Cell 124(3), 615-629 (2006). (Pubitemid 43199445)
-
(2006)
Cell
, vol.124
, Issue.3
, pp. 615-629
-
-
Zhu, P.1
Baek, S.H.2
Bourk, E.M.3
Ohgi, K.A.4
Garcia-Bassets, I.5
Sanjo, H.6
Akira, S.7
Kotol, P.F.8
Glass, C.K.9
Rosenfeld, M.G.10
Rose, D.W.11
-
39
-
-
33747345981
-
Classical and alternative activation of mononuclear phagocytes: Picking the best of both worlds for tumor promotion
-
DOI 10.1016/j.imbio.2006.06.002, PII S0171298506000829
-
Van Ginderachter JA, Movahedi K, Hassanzadeh Ghassabeh G et al.: Classical and alternative activation of mononuclear phagocytes: picking the best of both worlds for tumor promotion. Immunobiology 211(6-8), 487-501 (2006). (Pubitemid 44241651)
-
(2006)
Immunobiology
, vol.211
, Issue.6-8
, pp. 487-501
-
-
Van Ginderachter, J.A.1
Movahedi, K.2
Hassanzadeh Ghassabeh, G.3
Meerschaut, S.4
Beschin, A.5
Raes, G.6
De Baetselier, P.7
-
40
-
-
3142644996
-
Tumour-associated macrophages as a prototypic type II polarised phagocyte population: Role in tumour progression
-
DOI 10.1016/j.ejca.2004.03.016, PII S0959804904002850
-
Mantovani A, Allavena P, Sica A: Tumour-associated macrophages as a prototypic type II polarised phagocyte population: role in tumour progression. Eur. J. Cancer 40(11), 1660-1667 (2004). (Pubitemid 38902900)
-
(2004)
European Journal of Cancer
, vol.40
, Issue.11
, pp. 1660-1667
-
-
Mantovani, A.1
Allavena, P.2
Sica, A.3
-
41
-
-
0347123433
-
Tumour-educated macrophages promote tumour progression and metastasis
-
Pollard JW: Tumour-educated macrophages promote tumour progression and metastasis. Nat. Rev. Cancer 4(1), 71-78 (2004).
-
(2004)
Nat. Rev. Cancer
, vol.4
, Issue.1
, pp. 71-78
-
-
Pollard, J.W.1
-
42
-
-
47949090079
-
The role of myeloid cells in the promotion of tumour angiogenesis
-
Murdoch C, Muthana M, Coffelt SB, Lewis CE: The role of myeloid cells in the promotion of tumour angiogenesis. Nat. Rev. Cancer 8(8), 618-631 (2008).
-
(2008)
Nat. Rev. Cancer
, vol.8
, Issue.8
, pp. 618-631
-
-
Murdoch, C.1
Muthana, M.2
Coffelt, S.B.3
Lewis, C.E.4
-
43
-
-
33845466231
-
Monocyte/macrophage infiltration in tumors: Modulators of angiogenesis
-
Dirkx AE, Oude Egbrink MG, Wagstaff J, Griffioen AW: Monocyte/macrophage infiltration in tumors: modulators of angiogenesis. J. Leukoc. Biol. 80(6), 1183-1196 (2006).
-
(2006)
J. Leukoc. Biol.
, vol.80
, Issue.6
, pp. 1183-1196
-
-
Dirkx, A.E.1
Oude Egbrink, M.G.2
Wagstaff, J.3
Griffioen, A.W.4
-
44
-
-
0037686184
-
Host microenvironment in breast cancer development: Inflammatory and immune cells in tumour angiogenesis and arteriogenesis
-
Yu JL, Rak JW: Host microenvironment in breast cancer development: inflammatory and immune cells in tumour angiogenesis and arteriogenesis. Breast Cancer Res. 5(2), 83-88 (2003).
-
(2003)
Breast Cancer Res.
, vol.5
, Issue.2
, pp. 83-88
-
-
Yu, J.L.1
Rak, J.W.2
-
45
-
-
47049089532
-
Nitric oxide, apoptosis and macrophage polarization during tumor progression
-
Weigert A, Brune B: Nitric oxide, apoptosis and macrophage polarization during tumor progression. Nitric Oxide 19(2), 95-102 (2008).
-
(2008)
Nitric Oxide
, vol.19
, Issue.2
, pp. 95-102
-
-
Weigert, A.1
Brune, B.2
-
46
-
-
42149099408
-
Plasticity of macrophage function during tumor progression: Regulation by distinct molecular mechanisms
-
Biswas SK, Sica A, Lewis CE: Plasticity of macrophage function during tumor progression: regulation by distinct molecular mechanisms. J. Immunol. 180(4), 2011-2017 (2008).
-
(2008)
J. Immunol.
, vol.180
, Issue.4
, pp. 2011-2017
-
-
Biswas, S.K.1
Sica, A.2
Lewis, C.E.3
-
47
-
-
47949096781
-
Cancer-related inflammation
-
Mantovani A, Allavena P, Sica A, Balkwill F: Cancer-related inflammation. Nature 454(7203), 436-444 (2008).
-
(2008)
Nature
, vol.454
, Issue.7203
, pp. 436-444
-
-
Mantovani, A.1
Allavena, P.2
Sica, A.3
Balkwill, F.4
-
48
-
-
25844459154
-
NF-κB: Linking inflammation and immunity to cancer development and progression
-
Karin M, Greten FR: NF-κB: linking inflammation and immunity to cancer development and progression. Nat. Rev. Immunol. 5(10), 749-759 (2005).
-
(2005)
Nat. Rev. Immunol.
, vol.5
, Issue.10
, pp. 749-759
-
-
Karin, M.1
Greten, F.R.2
-
49
-
-
45149134605
-
'Re-educating' tumor-associated macrophages by targeting NF-κB
-
Hagemann T, Lawrence T, McNeish I et al.: 'Re-educating' tumor-associated macrophages by targeting NF-κB. J. Exp. Med. 205(6), 1261-1268 (2008).
-
(2008)
J. Exp. Med.
, vol.205
, Issue.6
, pp. 1261-1268
-
-
Hagemann, T.1
Lawrence, T.2
McNeish, I.3
-
50
-
-
45149087674
-
An antiinflammatory role for IKKβ through the inhibition of 'classical' macrophage activation
-
Fong CH, Bebien M, Didierlaurent A et al.: An antiinflammatory role for IKKβ through the inhibition of 'classical' macrophage activation. J. Exp. Med. 205(6), 1269-1276 (2008).
-
(2008)
J. Exp. Med.
, vol.205
, Issue.6
, pp. 1269-1276
-
-
Fong, Ch.1
Bebien, M.2
Didierlaurent, A.3
-
51
-
-
33845752914
-
P50 nuclear factor-κB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance
-
DOI 10.1158/0008-5472.CAN-06-1867
-
Saccani A, Schioppa T, Porta C et al.: p50 nuclear factor-κB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance. Cancer Res. 66(23), 11432-11440 (2006). (Pubitemid 46009975)
-
(2006)
Cancer Research
, vol.66
, Issue.23
, pp. 11432-11440
-
-
Saccani, A.1
Schioppa, T.2
Porta, C.3
Biswas, S.K.4
Nebuloni, M.5
Vago, L.6
Bottazzi, B.7
Colombo, M.P.8
Mantovani, A.9
Sica, A.10
-
52
-
-
33344460032
-
A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-κB and enhanced IRF-3/STAT1 activation)
-
DOI 10.1182/blood-2005-01-0428
-
Biswas SK, Gangi L, Paul S et al.: A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-κB and enhanced IRF-3/STAT1 activation). Blood 107(5), 2112-2122 (2006). (Pubitemid 43289397)
-
(2006)
Blood
, vol.107
, Issue.5
, pp. 2112-2122
-
-
Biswas, S.K.1
Gangi, L.2
Paul, S.3
Schioppa, T.4
Saccani, A.5
Sironi, M.6
Bottazzi, B.7
Doni, A.8
Vincenzo, B.9
Pasqualini, F.10
Vago, L.11
Nebuloni, M.12
Mantovani, A.13
Sica, A.14
-
53
-
-
34249826961
-
Cutting edge: Involvement of the type I IFN production and signaling pathway in lipopolysaccharide-induced IL-10 production
-
Chang EY, Guo B, Doyle SE, Cheng G: Cutting edge: involvement of the type I IFN production and signaling pathway in lipopolysaccharide-induced IL-10 production. J. Immunol. 178(11), 6705-6709 (2007). (Pubitemid 46847391)
-
(2007)
Journal of Immunology
, vol.178
, Issue.11
, pp. 6705-6709
-
-
Chang, E.Y.1
Guo, B.2
Doyle, S.E.3
Cheng, G.4
-
54
-
-
17044366637
-
STAT1 signaling regulates tumor-associated macrophage-mediated T cell deletion
-
Kusmartsev S, Gabrilovich DI: STAT1 signaling regulates tumor-associated macrophage-mediated TB lymphocyte deletion. J. Immunol. 174(8), 4880-4891 (2005). (Pubitemid 40504572)
-
(2005)
Journal of Immunology
, vol.174
, Issue.8
, pp. 4880-4891
-
-
Kusmartsev, S.1
Gabrilovich, D.I.2
-
55
-
-
28544439921
-
Diminished expression of transcription factors nuclear factor κB and CCAAT/enhancer binding protein underlies a novel tumor evasion mechanism affecting macrophages of mammary tumor-bearing mice
-
DOI 10.1158/0008-5472.CAN-05-0365
-
Torroella-Kouri M, Ma X, Perry G et al.: Diminished expression of transcription factors nuclear factor κB and CCAAT/enhancer binding protein underlies a novel tumor evasion mechanism affecting macrophages of mammary tumor-bearing mice. Cancer Res. 65(22), 10578-10584 (2005). (Pubitemid 41743753)
-
(2005)
Cancer Research
, vol.65
, Issue.22
, pp. 10578-10584
-
-
Torroella-Kouri, M.1
Ma, X.2
Perry, G.3
Ivanova, M.4
Cejas, P.J.5
Owen, J.L.6
Iragavarapu-Charyulu, V.7
Lopez, D.M.8
-
56
-
-
33845970925
-
Parallel SUMOylation-Dependent Pathways Mediate Gene- And Signal-Specific Transrepression by LXRs and PPARγ
-
DOI 10.1016/j.molcel.2006.11.022, PII S1097276506008161
-
Ghisletti S, Huang W, Ogawa S et al.: Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARγ. Mol. Cell 25(1), 57-70 (2007). (Pubitemid 46049061)
-
(2007)
Molecular Cell
, vol.25
, Issue.1
, pp. 57-70
-
-
Ghisletti, S.1
Huang, W.2
Ogawa, S.3
Pascual, G.4
Lin, M.-E.5
Willson, T.M.6
Rosenfeld, M.G.7
Glass, C.K.8
-
57
-
-
26444471700
-
A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ
-
DOI 10.1038/nature03988, PII N03988
-
Pascual G, Fong AL, Ogawa S et al.: A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ. Nature 437(7059), 759-763 (2005). (Pubitemid 41486547)
-
(2005)
Nature
, vol.437
, Issue.7059
, pp. 759-763
-
-
Pascual, G.1
Fong, A.L.2
Ogawa, S.3
Gamliel, A.4
Li, A.C.5
Perissi, V.6
Rose, D.W.7
Willson, T.M.8
Rosenfeld, M.G.9
Glass, C.K.10
-
58
-
-
34250823515
-
Gene-specific control of inflammation by TLR-induced chromatin modifications
-
Demonstrates an important self-regulation mechanism of inflammatory cells
-
Foster SL, Hargreaves DC, Medzhitov R: Gene-specific control of inflammation by TLR-induced chromatin modifications. Nature 447(7147), 972-978 (2007). ■ Demonstrates an important self-regulation mechanism of inflammatory cells.
-
(2007)
Nature
, vol.447
, Issue.7147
, pp. 972-978
-
-
Foster, S.L.1
Hargreaves, D.C.2
Medzhitov, R.3
-
59
-
-
22644446255
-
Tuning of macrophage responses by Stat3-inducing cytokines: Molecular mechanisms and consequences in infection
-
Lang R: Tuning of macrophage responses by Stat3-inducing cytokines: molecular mechanisms and consequences in infection. Immunobiology 210(2-4), 63-76 (2005).
-
(2005)
Immunobiology
, vol.210
, Issue.2-4
, pp. 63-76
-
-
Lang, R.1
-
60
-
-
33750570923
-
Heat shock protein 70 is secreted from tumor cells by a nonclassical pathway involving lysosomal endosomes
-
Mambula SS, Calderwood SK: Heat shock protein 70 is secreted from tumor cells by a nonclassical pathway involving lysosomal endosomes. J. Immunol. 177(11), 7849-7857 (2006).
-
(2006)
J. Immunol.
, vol.177
, Issue.11
, pp. 7849-7857
-
-
Mambula, S.S.1
Calderwood, S.K.2
-
61
-
-
27744603002
-
Hypoxia regulates macrophage functions in inflammation
-
Murdoch C, Muthana M, Lewis CE: Hypoxia regulates macrophage functions in inflammation. J. Immunol. 175(10), 6257-6263 (2005). (Pubitemid 41598863)
-
(2005)
Journal of Immunology
, vol.175
, Issue.10
, pp. 6257-6263
-
-
Murdoch, C.1
Muthana, M.2
Lewis, C.E.3
-
62
-
-
44849100198
-
NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α
-
DOI 10.1038/nature06905, PII NATURE06905
-
Rius J, Guma M, Schachtrup C et al.: NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α. Nature 453(7196), 807-811 (2008). ■ Provides an important link between inflammation and hypoxic signaling. (Pubitemid 351793778)
-
(2008)
Nature
, vol.453
, Issue.7196
, pp. 807-811
-
-
Rius, J.1
Guma, M.2
Schachtrup, C.3
Akassoglou, K.4
Zinkernagel, A.S.5
Nizet, V.6
Johnson, R.S.7
Haddad, G.G.8
Karin, M.9
-
63
-
-
0037423948
-
HIF-1α is essential for myeloid cell-mediated inflammation
-
DOI 10.1016/S0092-8674(03)00154-5
-
Cramer T, Yamanishi Y, Clausen BE et al.: HIF-1α is essential for myeloid cell-mediated inflammation. Cell 112(5), 645-657 (2003). (Pubitemid 36331777)
-
(2003)
Cell
, vol.112
, Issue.5
, pp. 645-657
-
-
Cramer, T.1
Yamanishi, Y.2
Clausen, B.E.3
Forster, I.4
Pawlinski, R.5
Mackman, N.6
Haase, V.H.7
Jaenisch, R.8
Corr, M.9
Nizet, V.10
Firestein, G.S.11
Gerber, H.-P.12
Ferrara, N.13
Johnson, R.S.14
-
64
-
-
34250158361
-
Cutting edge: Essential role of hypoxia inducible factor-1α in development of lipopolysaccharide-induced sepsis
-
Peyssonnaux C, Cejudo-Martin P, Doedens A, Zinkernagel AS, Johnson RS, Nizet V: Cutting edge: essential role of hypoxia inducible factor-1α in development of lipopolysaccharide-induced sepsis. J. Immunol. 178(12), 7516-7519 (2007). (Pubitemid 46898018)
-
(2007)
Journal of Immunology
, vol.178
, Issue.12
, pp. 7516-7519
-
-
Peyssonnaux, C.1
Cejudo-Martin, P.2
Doedens, A.3
Zinkernagel, A.S.4
Johnson, R.S.5
Nizet, V.6
-
65
-
-
0033870281
-
The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages
-
Talks KL, Turley H, Gatter KC et al.: The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages. Am. J. Pathol. 157(2), 411-421 (2000).
-
(2000)
Am. J. Pathol.
, vol.157
, Issue.2
, pp. 411-421
-
-
Talks, K.L.1
Turley, H.2
Gatter, K.C.3
-
66
-
-
0034641931
-
Corpse clearance defines the meaning of cell death
-
DOI 10.1038/35037722
-
Savill J, Fadok V: Corpse clearance defines the meaning of cell death. Nature 407(6805), 784-788 (2000). (Pubitemid 30780741)
-
(2000)
Nature
, vol.407
, Issue.6805
, pp. 784-788
-
-
Savill, J.1
Fadok, V.2
-
67
-
-
34948820602
-
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy
-
Apetoh L, Ghiringhelli F, Tesniere A et al.: Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat. Med. 13(9), 1050-1059 (2007).
-
(2007)
Nat. Med.
, vol.13
, Issue.9
, pp. 1050-1059
-
-
Apetoh, L.1
Ghiringhelli, F.2
Tesniere, A.3
-
68
-
-
35748942876
-
The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy
-
Apetoh L, Ghiringhelli F, Tesniere A et al.: The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy. Immunol. Rev. 220, 47-59 (2007).
-
(2007)
Immunol. Rev.
, vol.220
, pp. 47-59
-
-
Apetoh, L.1
Ghiringhelli, F.2
Tesniere, A.3
-
69
-
-
33750631646
-
Effector mechanisms of the anti-cancer immune responses of macrophages in SR/CR mice
-
Hicks AM, Willingham MC, Du W, Pang CS, Old LJ, Cui Z: Effector mechanisms of the anti-cancer immune responses of macrophages in SR/CR mice. Cancer Immun. 6, 11 (2006).
-
(2006)
Cancer Immun.
, vol.6
, pp. 11
-
-
Hicks, A.M.1
Willingham, M.C.2
Du, W.3
Pang, C.S.4
Old, L.J.5
Cui, Z.6
-
70
-
-
0036884424
-
A blast from the past: Clearance of apoptotic cells regulates immune responses
-
Savill J, Dransfield I, Gregory C, Haslett C: A blast from the past: clearance of apoptotic cells regulates immune responses. Nat. Rev. Immunol. 2(12), 965-975 (2002).
-
(2002)
Nat. Rev. Immunol.
, vol.2
, Issue.12
, pp. 965-975
-
-
Savill, J.1
Dransfield, I.2
Gregory, C.3
Haslett, C.4
-
71
-
-
0033566932
-
Cutting edge: Differential effects of apoptotic versus necrotic tumor cells on macrophage antitumor activities
-
Reiter I, Krammer B, Schwamberger G: Cutting edge: differential effect of apoptotic versus necrotic tumor cells on macrophage antitumor activities. J. Immunol. 163(4), 1730-1732 (1999). (Pubitemid 29382166)
-
(1999)
Journal of Immunology
, vol.163
, Issue.4
, pp. 1730-1732
-
-
Reiter, I.1
Krammer, B.2
Schwamberger, G.3
-
72
-
-
8644274867
-
Inhibition of phosphatidylserine recognition heightens the immunogenicity of irradiated lymphoma cells in vivo
-
Bondanza A, Zimmermann VS, Rovere-Querini P et al.: Inhibition of phosphatidylserine recognition heightens the immunogenicity of irradiated lymphoma cells in vivo. J. Exp. Med. 200(9), 1157-1165 (2004).
-
(2004)
J. Exp. Med.
, vol.200
, Issue.9
, pp. 1157-1165
-
-
Bondanza, A.1
Zimmermann, V.S.2
Rovere-Querini, P.3
-
73
-
-
33748178875
-
Apoptotic cells promote macrophage survival by releasing the antiapoptotic mediator sphingosine-1-phosphate
-
DOI 10.1182/blood-2006-04-014852
-
Weigert A, Johann AM, von Knethen A, Schmidt H, Geisslinger G, Brune B: Apoptotic cells promote macrophage survival by releasing the antiapoptotic mediator sphingosine-1-phosphate. Blood 108(5), 1635-1642 (2006). (Pubitemid 44316132)
-
(2006)
Blood
, vol.108
, Issue.5
, pp. 1635-1642
-
-
Weigert, A.1
Johann, A.M.2
Von Knethen, A.3
Schmidt, H.4
Geisslinger, G.5
Brune, B.6
-
74
-
-
48749121214
-
Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a 'come-and-get-me' signal
-
Gude DR, Alvarez SE, Paugh SW et al.: Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a 'come-and-get-me' signal. FASEB J. 22(8), 2629-2638 (2008).
-
(2008)
FASEB J.
, vol.22
, Issue.8
, pp. 2629-2638
-
-
Gude, D.R.1
Alvarez, S.E.2
Paugh, S.W.3
-
75
-
-
42549148380
-
Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages
-
Hughes JE, Srinivasan S, Lynch KR, Proia RL, Ferdek P, Hedrick CC: Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages. Circ. Res. 102(8), 950-958 (2008).
-
(2008)
Circ. Res.
, vol.102
, Issue.8
, pp. 950-958
-
-
Hughes, J.E.1
Srinivasan, S.2
Lynch, K.R.3
Proia, R.L.4
Ferdek, P.5
Hedrick, C.C.6
-
76
-
-
34948853738
-
Tumor cell apoptosis polarizes macrophages role of sphingosine-1- phosphate
-
Weigert A, Tzieply N, von Knethen A et al.: Tumor cell apoptosis polarizes macrophages role of sphingosine-1-phosphate. Mol. Biol. Cell 18(10), 3810-3819 (2007).
-
(2007)
Mol. Biol. Cell
, vol.18
, Issue.10
, pp. 3810-3819
-
-
Weigert, A.1
Tzieply, N.2
Von Knethen, A.3
-
77
-
-
33644830810
-
Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages
-
DOI 10.1016/j.ccr.2006.02.023, PII S1535610806000584
-
Visentin B, Vekich JA, Sibbald BJ et al.: Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages. Cancer Cell 9(3), 225-238 (2006). (Pubitemid 43357948)
-
(2006)
Cancer Cell
, vol.9
, Issue.3
, pp. 225-238
-
-
Visentin, B.1
Vekich, J.A.2
Sibbald, B.J.3
Cavalli, A.L.4
Moreno, K.M.5
Matteo, R.G.6
Garland, W.A.7
Lu, Y.8
Yu, S.9
Hall, H.S.10
Kundra, V.11
Mills, G.B.12
Sabbadini, R.A.13
-
78
-
-
28044445899
-
Role of immature myeloid cells in mechanisms of immune evasion in cancer
-
Kusmartsev S, Gabrilovich DI: Role of immature myeloid cells in mechanisms of immune evasion in cancer. Cancer Immunol. Immunother. 55(3), 237-245 (2006).
-
(2006)
Cancer Immunol. Immunother.
, vol.55
, Issue.3
, pp. 237-245
-
-
Kusmartsev, S.1
Gabrilovich, D.I.2
-
79
-
-
33845767868
-
Macrophages regulate the angiogenic switch in a mouse model of breast cancer
-
DOI 10.1158/0008-5472.CAN-06-1278
-
Lin EY, Li JF, Gnatovskiy L et al.: Macrophages regulate the angiogenic switch in a mouse model of breast cancer. Cancer Res. 66(23), 11238-11246 (2006). (Pubitemid 46009952)
-
(2006)
Cancer Research
, vol.66
, Issue.23
, pp. 11238-11246
-
-
Lin, E.Y.1
Li, J.-F.2
Gnatovskiy, L.3
Deng, Y.4
Zhu, L.5
Grzesik, D.A.6
Qian, H.7
Xue, X.-N.8
Pollard, J.W.9
-
80
-
-
36549025804
-
VEGF restores delayed tumor progression in tumors depleted of macrophages
-
Lin EY, Li JF, Bricard G et al.: VEGF restores delayed tumor progression in tumors depleted of macrophages. Mol. Oncol. 1(3), 288-302 (2007).
-
(2007)
Mol. Oncol.
, vol.1
, Issue.3
, pp. 288-302
-
-
Lin, E.Y.1
Li, J.F.2
Bricard, G.3
-
81
-
-
0037105725
-
Colony-stimulating factor-1 antisense treatment suppresses growth of human tumor xenografts in mice
-
Aharinejad S, Abraham D, Paulus P et al.: Colony-stimulating factor-1 antisense treatment suppresses growth of human tumor xenografts in mice. Cancer Res. 62(18), 5317-5324 (2002). (Pubitemid 35024608)
-
(2002)
Cancer Research
, vol.62
, Issue.18
, pp. 5317-5324
-
-
Aharinejad, S.1
Abraham, D.2
Paulus, P.3
Abri, H.4
Hofmann, M.5
Grossschmidt, K.6
Schiller, R.7
Stanley, E.R.8
Hofbauer, R.9
-
82
-
-
34447556692
-
Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft
-
Gazzaniga S, Bravo AI, Guglielmotti A et al.: Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft. J. Invest. Dermatol. 127(8), 2031-2041 (2007).
-
(2007)
J. Invest. Dermatol.
, vol.127
, Issue.8
, pp. 2031-2041
-
-
Gazzaniga, S.1
Bravo, A.I.2
Guglielmotti, A.3
-
83
-
-
35148852659
-
Targeting CCL2 with systemic delivery of neutralizing antibodies induces prostate cancer tumor regression in vivo
-
DOI 10.1158/0008-5472.CAN-07-1286
-
Loberg RD, Ying C, Craig M et al.: Targeting CCL2 with systemic delivery of neutralizing antibodies induces prostate cancer tumor regression in vivo. Cancer Res. 67(19), 9417-9424 (2007). (Pubitemid 47535932)
-
(2007)
Cancer Research
, vol.67
, Issue.19
, pp. 9417-9424
-
-
Loberg, R.D.1
Ying, C.2
Craig, M.3
Day, L.L.4
Sargent, E.5
Neeley, C.6
Wojno, K.7
Snyder, L.A.8
Yan, L.9
Pienta, K.J.10
-
84
-
-
24944541787
-
Plasminogen kringle 5-engineered glioma cells block migration of tumor-associated macrophages and suppress tumor vascularization and progression
-
DOI 10.1158/0008-5472.CAN-05-0508
-
Perri SR, Nalbantoglu J, Annabi B et al.: Plasminogen kringle 5-engineered glioma cells block migration of tumor-associated macrophages and suppress tumor vascularization and progression. Cancer Res. 65(18), 8359-8365 (2005). (Pubitemid 41330601)
-
(2005)
Cancer Research
, vol.65
, Issue.18
, pp. 8359-8365
-
-
Perri, S.R.1
Nalbantoglu, J.2
Annabi, B.3
Koty, Z.4
Lejeune, L.5
Francois, M.6
Di Falco, M.R.7
Beliveau, R.8
Galipeau, J.9
-
85
-
-
37049006066
-
Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma
-
DOI 10.1158/0008-5472.CAN-07-1882
-
Melani C, Sangaletti S, Barazzetta FM, Werb Z, Colombo MP: Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma. Cancer Res. 67(23), 11438-11446 (2007). (Pubitemid 350248572)
-
(2007)
Cancer Research
, vol.67
, Issue.23
, pp. 11438-11446
-
-
Melani, C.1
Sangaletti, S.2
Barazzetta, F.M.3
Werb, Z.4
Colombo, M.P.5
-
86
-
-
20144388299
-
Anti-inflammatory properties of the novel antitumor agent Yondelis (Trabectedin): Inhibition of macrophage differentiation and cytokine production
-
DOI 10.1158/0008-5472.CAN-04-4037
-
Allavena P, Signorelli M, Chieppa M et al.: Anti-inflammatory properties of the novel antitumor agent yondelis (trabectedin): inhibition of macrophage differentiation and cytokine production. Cancer Res. 65(7), 2964-2971 (2005). (Pubitemid 40490102)
-
(2005)
Cancer Research
, vol.65
, Issue.7
, pp. 2964-2971
-
-
Allavena, P.1
Signorelli, M.2
Chieppa, M.3
Erba, E.4
Bianchi, G.5
Marchesi, F.6
Olimpio, C.O.7
Bonardi, C.8
Garbi, A.9
Lissoni, A.10
De Braud, F.11
Jimeno, J.12
D'Incalci, M.13
-
87
-
-
33846124005
-
Macrophage-targeted photosensitizer conjugate delivered by intratumoral injection
-
Anatelli F, Mroz P, Liu Q et al.: Macrophage-targeted photosensitizer conjugate delivered by intratumoral injection. Mol. Pharm. 3(6), 654-664 (2006).
-
(2006)
Mol. Pharm.
, vol.3
, Issue.6
, pp. 654-664
-
-
Anatelli, F.1
Mroz, P.2
Liu, Q.3
-
88
-
-
33746926292
-
Clodronate-liposome-mediated depletion of tumour-associated macrophages: A new and highly effective antiangiogenic therapy approach
-
DOI 10.1038/sj.bjc.6603240, PII 6603240
-
Zeisberger SM, Odermatt B, Marty C, Zehnder-Fjallman AH, Ballmer-Hofer K, Schwendener RA: Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach. Br. J. Cancer 95(3), 272-281 (2006). (Pubitemid 44187587)
-
(2006)
British Journal of Cancer
, vol.95
, Issue.3
, pp. 272-281
-
-
Zeisberger, S.M.1
Odermatt, B.2
Marty, C.3
Zehnder-Fjallman, A.H.M.4
Ballmer-Hofer, K.5
Schwendener, R.A.6
-
89
-
-
42249115328
-
Targeting tumor-associated macrophages in an orthotopic murine model of diffuse malignant mesothelioma
-
Miselis NR, Wu ZJ, Van Rooijen N, Kane AB: Targeting tumor-associated macrophages in an orthotopic murine model of diffuse malignant mesothelioma. Mol. Cancer Ther. 7(4), 788-799 (2008).
-
(2008)
Mol. Cancer Ther.
, vol.7
, Issue.4
, pp. 788-799
-
-
Miselis, N.R.1
Wu, Z.J.2
Van Rooijen, N.3
Kane, A.B.4
-
90
-
-
39049168150
-
Antitumor activity of liposomal prednisolone phosphate depends on the presence of functional tumor-associated macrophages in tumor tissue
-
DOI 10.1593/neo.07913
-
Banciu M, Metselaar JM, Schiffelers RM, Storm G: Antitumor activity of liposomal prednisolone phosphate depends on the presence of functional tumor-associated macrophages in tumor tissue. Neoplasia 10(2), 108-117 (2008). (Pubitemid 351240876)
-
(2008)
Neoplasia
, vol.10
, Issue.2
, pp. 108-117
-
-
Banciu, M.1
Metselaar, J.M.2
Schiffelers, R.M.3
Storm, G.4
-
91
-
-
46749088943
-
Investigation into the role of tumor-associated macrophages in the antitumor activity of doxil
-
Banciu M, Schiffelers RM, Storm G: Investigation into the role of tumor-associated macrophages in the antitumor activity of doxil. Pharm. Res. 25(8), 1948-1955 (2008).
-
(1948)
Pharm. Res.
, vol.25
, Issue.8
, pp. 2008
-
-
Banciu, M.1
Schiffelers, R.M.2
Storm, G.3
-
92
-
-
33746718151
-
Targeting tumor-associated macrophages as a novel strategy against breast cancer
-
Luo Y, Zhou H, Krueger J et al.: Targeting tumor-associated macrophages as a novel strategy against breast cancer. J. Clin. Invest. 116(8), 2132-2141 (2006).
-
(2006)
J. Clin. Invest.
, vol.116
, Issue.8
, pp. 2132-2141
-
-
Luo, Y.1
Zhou, H.2
Krueger, J.3
-
93
-
-
41149088925
-
Oral DNA vaccines target the tumor vasculature and microenvironment and suppress tumor growth and metastasis
-
Xiang R, Luo Y, Niethammer AG, Reisfeld RA: Oral DNA vaccines target the tumor vasculature and microenvironment and suppress tumor growth and metastasis. Immunol. Rev. 222, 117-128 (2008).
-
(2008)
Immunol. Rev.
, vol.222
, pp. 117-128
-
-
Xiang, R.1
Luo, Y.2
Niethammer, A.G.3
Reisfeld, R.A.4
-
94
-
-
0030904517
-
Effects of neutrophil, natural killer cell, and macrophage depletion on murine Clostridium piliforme infection
-
Van Andel RA, Hook RR Jr, Franklin CL, Besch-Williford CL, van Rooijen N, Riley LK: Effects of neutrophil, natural killer cell, and macrophage depletion on murine Clostridium piliforme infection. Infect. Immun. 65(7), 2725-2731 (1997).
-
(1997)
Infect. Immun.
, vol.65
, Issue.7
, pp. 2725-2731
-
-
Van Andel, R.A.1
Hook Jr., R.R.2
Franklin, C.L.3
Besch-Williford, C.L.4
Van Rooijen, N.5
Riley, L.K.6
-
95
-
-
41649116240
-
Plasticity in tumor-promoting inflammation: Impairment of macrophage recruitment evokes a compensatory neutrophil response
-
Pahler JC, Tazzyman S, Erez N et al.: Plasticity in tumor-promoting inflammation: impairment of macrophage recruitment evokes a compensatory neutrophil response. Neoplasia 10(4), 329-340 (2008).
-
(2008)
Neoplasia
, vol.10
, Issue.4
, pp. 329-340
-
-
Pahler, J.C.1
Tazzyman, S.2
Erez, N.3
-
96
-
-
34548760331
-
Increased glioma growth in mice depleted of macrophages
-
DOI 10.1158/0008-5472.CAN-07-0177
-
Galarneau H, Villeneuve J, Gowing G, Julien JP, Vallieres L: Increased glioma growth in mice depleted of macrophages. Cancer Res. 67(18), 8874-8881 (2007). (Pubitemid 47437464)
-
(2007)
Cancer Research
, vol.67
, Issue.18
, pp. 8874-8881
-
-
Galarneau, H.1
Villeneuve, J.2
Gowing, G.3
Julien, J.-P.4
Vallieres, L.5
-
97
-
-
44449112373
-
Chaperone-rich tumor cell lysate-mediated activation of antigen-presenting cells resists regulatory TB lymphocyte suppression
-
Larmonier N, Cantrell J, Lacasse C et al.: Chaperone-rich tumor cell lysate-mediated activation of antigen-presenting cells resists regulatory TB lymphocyte suppression. J. Leukoc. Biol. 83(4), 1049-1059 (2008).
-
(2008)
J. Leukoc. Biol.
, vol.83
, Issue.4
, pp. 1049-1059
-
-
Larmonier, N.1
Cantrell, J.2
Lacasse, C.3
-
98
-
-
38549095046
-
PPARα deficiency in inflammatory cells suppresses tumor growth
-
Kaipainen A, Kieran MW, Huang S et al.: PPARα deficiency in inflammatory cells suppresses tumor growth. PLoS ONE 2(2), e260 (2007).
-
(2007)
PLoS ONE
, vol.2
, Issue.2
-
-
Kaipainen, A.1
Kieran, M.W.2
Huang, S.3
-
99
-
-
34248172324
-
Altered macrophage differentiation and immune dysfunction in tumor development
-
Sica A, Bronte V: Altered macrophage differentiation and immune dysfunction in tumor development. J. Clin. Invest. 117(5), 1155-1166 (2007).
-
(2007)
J. Clin. Invest.
, vol.117
, Issue.5
, pp. 1155-1166
-
-
Sica, A.1
Bronte, V.2
-
100
-
-
33644775602
-
An oligonucleotide decoy for Stat3 activates the immune response of macrophages to breast cancer
-
DOI 10.1016/j.imbio.2005.11.004, PII S0171298506000167
-
Sun Z, Yao Z, Liu S, Tang H, Yan X: An oligonucleotide decoy for Stat3 activates the immune response of macrophages to breast cancer. Immunobiology 211(3), 199-209 (2006). (Pubitemid 43337760)
-
(2006)
Immunobiology
, vol.211
, Issue.3
, pp. 199-209
-
-
Sun, Z.1
Yao, Z.2
Liu, S.3
Tang, H.4
Yan, X.5
-
101
-
-
35448979864
-
A novel small molecule inhibitor of signal transducers and activators of transcription 3 reverses immune tolerance in malignant glioma patients
-
DOI 10.1158/0008-5472.CAN-07-1243
-
Hussain SF, Kong LY, Jordan J et al.: A novel small molecule inhibitor of signal transducers and activators of transcription 3 reverses immune tolerance in malignant glioma patients. Cancer Res. 67(20), 9630-9636 (2007). (Pubitemid 47621208)
-
(2007)
Cancer Research
, vol.67
, Issue.20
, pp. 9630-9636
-
-
Hussain, S.F.1
Kong, L.-Y.2
Jordan, J.3
Conrad, C.4
Madden, T.5
Fokt, I.6
Priebe, W.7
Heimberger, A.B.8
-
102
-
-
26644437199
-
SHIP represses the generation of alternatively activated macrophages
-
DOI 10.1016/j.immuni.2005.09.003, PII S1074761305002761
-
Rauh MJ, Ho V, Pereira C et al.: SHIP represses the generation of alternatively activated macrophages. Immunity 23(4), 361-374 (2005). (Pubitemid 41443438)
-
(2005)
Immunity
, vol.23
, Issue.4
, pp. 361-374
-
-
Rauh, M.J.1
Ho, V.2
Pereira, C.3
Sham, A.4
Sly, L.M.5
Lam, V.6
Huxham, L.7
Minchinton, A.I.8
Mui, A.9
Krystal, G.10
-
103
-
-
34249828198
-
The PI3K/Akt pathway and its downstream transcriptional factors as targets for chemoprevention
-
DOI 10.2174/156800907780809741
-
Zhang X, Jin B, Huang C: The PI3K/Akt pathway and its downstream transcriptional factors as targets for chemoprevention. Curr. Cancer Drug Targets 7(4), 305-316 (2007). (Pubitemid 46849235)
-
(2007)
Current Cancer Drug Targets
, vol.7
, Issue.4
, pp. 305-316
-
-
Zhang, X.1
Jin, B.2
Huang, C.3
-
104
-
-
33646549306
-
Tumoristatic effects of anti-CD40 mAb-activated macrophages involve nitric oxide and tumour necrosis factor-α
-
Lum HD, Buhtoiarov IN, Schmidt BE et al.: Tumoristatic effects of anti-CD40 mAb-activated macrophages involve nitric oxide and tumour necrosis factor-α. Immunology 118(2), 261-270 (2006).
-
(2006)
Immunology
, vol.118
, Issue.2
, pp. 261-270
-
-
Lum, H.D.1
Buhtoiarov, I.N.2
Schmidt, B.E.3
-
105
-
-
33846912817
-
Macrophages are essential for antitumour effects against weakly immunogenic murine tumours induced by class B CpG-oligodeoxynucleotides
-
Buhtoiarov IN, Sondel PM, Eickhoff JC, Rakhmilevich AL: Macrophages are essential for antitumour effects against weakly immunogenic murine tumours induced by class B CpG-oligodeoxynucleotides. Immunology 120(3), 412-423 (2007).
-
(2007)
Immunology
, vol.120
, Issue.3
, pp. 412-423
-
-
Buhtoiarov, I.N.1
Sondel, P.M.2
Eickhoff, J.C.3
Rakhmilevich, A.L.4
-
106
-
-
29644431786
-
Synergistic activation of macrophages via CD40 and TLR9 results in T cell independent antitumor effects
-
Buhtoiarov IN, Lum HD, Berke G, Sondel PM, Rakhmilevich AL: Synergistic activation of macrophages via CD40 and TLR9 results in TB lymphocyte independent antitumor effects. J. Immunol. 176(1), 309-318 (2006). (Pubitemid 43023276)
-
(2006)
Journal of Immunology
, vol.176
, Issue.1
, pp. 309-318
-
-
Buhtoiarov, I.N.1
Lum, H.D.2
Berke, G.3
Sondel, P.M.4
Rakhmilevich, A.L.5
-
107
-
-
42349106146
-
Expression of TLR9 within human glioblastoma
-
Meng Y, Kujas M, Marie Y et al.: Expression of TLR9 within human glioblastoma. J. Neurooncol. 88(1), 19-25 (2008).
-
(2008)
J. Neurooncol.
, vol.88
, Issue.1
, pp. 19-25
-
-
Meng, Y.1
Kujas, M.2
Marie, Y.3
-
108
-
-
31544468075
-
Phase 1 trial of a CpG oligodeoxynucleotide for patients with recurrent glioblastoma
-
Carpentier A, Laigle-Donadey F, Zohar S et al.: Phase 1 trial of a CpG oligodeoxynucleotide for patients with recurrent glioblastoma. Neuro. Oncol. 8(1), 60-66 (2006).
-
(2006)
Neuro. Oncol.
, vol.8
, Issue.1
, pp. 60-66
-
-
Carpentier, A.1
Laigle-Donadey, F.2
Zohar, S.3
-
109
-
-
46749137580
-
Epigenetic control of MHC class II expression in tumor-associated macrophages by decoy receptor 3
-
Chang YC, Chen TC, Lee CT et al.: Epigenetic control of MHC class II expression in tumor-associated macrophages by decoy receptor 3. Blood 111(10), 5054-5063 (2008).
-
(2008)
Blood
, vol.111
, Issue.10
, pp. 5054-5063
-
-
Chang, Y.C.1
Chen, T.C.2
Lee, C.T.3
-
110
-
-
36849085584
-
Immunotherapy of metastatic breast cancer patients with vitamin D-binding protein-derived macrophage activating factor (GcMAF)
-
DOI 10.1002/ijc.23107
-
Yamamoto N, Suyama H, Yamamoto N, Ushijima N: Immunotherapy of metastatic breast cancer patients with vitamin D-binding protein-derived macrophage activating factor (GcMAF). Int. J. Cancer 122(2), 461-467 (2008). (Pubitemid 350234736)
-
(2008)
International Journal of Cancer
, vol.122
, Issue.2
, pp. 461-467
-
-
Yamamoto, N.1
Suyama, H.2
Yamamoto, N.3
Ushijima, N.4
-
111
-
-
47949099098
-
Origin and physiological roles of inflammation
-
Medzhitov R: Origin and physiological roles of inflammation. Nature 454(7203), 428-435 (2008).
-
(2008)
Nature
, vol.454
, Issue.7203
, pp. 428-435
-
-
Medzhitov, R.1
-
112
-
-
0035339931
-
Engineering of macrophages to produce IFN-γ in response to hypoxia
-
Carta L, Pastorino S, Melillo G, Bosco MC, Massazza S, Varesio L: Engineering of macrophages to produce IFN-γ in response to hypoxia. J. Immunol. 166(9), 5374-5380 (2001). (Pubitemid 32374156)
-
(2001)
Journal of Immunology
, vol.166
, Issue.9
, pp. 5374-5380
-
-
Carta, L.1
Pastorino, S.2
Melillo, G.3
Bosco, M.C.4
Massazza, S.5
Varesio, L.6
-
113
-
-
34447121852
-
MFG-E8-mediated uptake of apoptotic cells by APCs links the pro- And anti-inflammatory activities of GM-CSF
-
Jinushi M, Nakazaki Y, Dougan M, Carrasco DR, Mihm M, Dranoff G: MFG-E8-mediated uptake of apoptotic cells by APCs links the pro- and anti-inflammatory activities of GM-CSF. J. Clin. Invest. 117(7), 1902-1913 (2007).
-
(1902)
J. Clin. Invest.
, vol.117
, Issue.7
, pp. 2007
-
-
Jinushi, M.1
Nakazaki, Y.2
Dougan, M.3
Carrasco, D.R.4
Mihm, M.5
Dranoff, G.6
-
114
-
-
34548204420
-
Post-translational regulation of human indoleamine 2,3-dioxygenase activity by nitric oxide
-
Thomas SR, Terentis AC, Cai H et al.: Post-translational regulation of human indoleamine 2,3-dioxygenase activity by nitric oxide. J. Biol. Chem. 282(33), 23778-23787 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, Issue.33
, pp. 23778-23787
-
-
Thomas, S.R.1
Terentis, A.C.2
Cai, H.3
-
115
-
-
30044449982
-
Resolution of inflammation: The beginning programs the end
-
Serhan CN, Savill J: Resolution of inflammation: the beginning programs the end. Nat. Immunol. 6(12), 1191-1197 (2005).
-
(2005)
Nat. Immunol.
, vol.6
, Issue.12
, pp. 1191-1197
-
-
Serhan, C.N.1
Savill, J.2
-
116
-
-
27744543102
-
Inflammatory cells during wound repair: The good, the bad and the ugly
-
DOI 10.1016/j.tcb.2005.09.002, PII S0962892405002278
-
Martin P, Leibovich SJ: Inflammatory cells during wound repair: the good, the bad and the ugly. Trends Cell. Biol 15(11), 599-607 (2005). (Pubitemid 41619424)
-
(2005)
Trends in Cell Biology
, vol.15
, Issue.11
, pp. 599-607
-
-
Martin, P.1
Leibovich, S.J.2
-
117
-
-
30144443269
-
Paradoxical roles of the immune system during cancer development
-
de Visser KE, Eichten A, Coussens LM: Paradoxical roles of the immune system during cancer development. Nat. Rev. Cancer 6(1), 24-37 (2006).
-
(2006)
Nat. Rev. Cancer
, vol.6
, Issue.1
, pp. 24-37
-
-
De Visser, K.E.1
Eichten, A.2
Coussens, L.M.3
-
118
-
-
0022891340
-
Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
-
Dvorak HF: Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N. Engl. J. Med. 315(26), 1650-1659 (1986).
-
(1986)
N. Engl. J. Med.
, vol.315
, Issue.26
, pp. 1650-1659
-
-
Dvorak, H.F.1
-
119
-
-
19344363035
-
Gene expression signature of fibroblast serum response predicts human cancer progression: Similarities between tumors and wounds
-
Chang HY, Sneddon JB, Alizadeh AA et al.: Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. PLoS Biol. 2(2), E7 (2004).
-
(2004)
PLoS Biol.
, vol.2
, Issue.2
-
-
Chang, H.Y.1
Sneddon, J.B.2
Alizadeh, A.A.3
-
120
-
-
44649110396
-
II. The influence of injury upon the development of sarcoma
-
Coley WB: II. The influence of injury upon the development of sarcoma. Ann. Surg. 27(3), 259-284 (1898).
-
(1898)
Ann. Surg.
, vol.27
, Issue.3
, pp. 259-284
-
-
Coley, W.B.1
-
121
-
-
4043088499
-
IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
DOI 10.1016/j.cell.2004.07.013, PII S0092867404006713
-
Greten FR, Eckmann L, Greten TF et al.: IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 118(3), 285-296 (2004). (Pubitemid 39061110)
-
(2004)
Cell
, vol.118
, Issue.3
, pp. 285-296
-
-
Greten, F.R.1
Eckmann, L.2
Greten, T.F.3
Park, J.M.4
Li, Z.-W.5
Egan, L.J.6
Kagnoff, M.F.7
Karin, M.8
-
122
-
-
32944474237
-
Innate immunity gone awry: Linking microbial infections to chronic inflammation and cancer
-
DOI 10.1016/j.cell.2006.02.016, PII S0092867406001917
-
Karin M, Lawrence T, Nizet V: Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell 124(4), 823-835 (2006). (Pubitemid 43261455)
-
(2006)
Cell
, vol.124
, Issue.4
, pp. 823-835
-
-
Karin, M.1
Lawrence, T.2
Nizet, V.3
-
123
-
-
53549123079
-
Immune-mediated dormancy: An equilibrium with cancer
-
Teng MW, Swann JB, Koebel CM, Schreiber RD, Smyth MJ: Immune-mediated dormancy: an equilibrium with cancer. J. Leukoc. Biol. 84(4), 988-993 (2008).
-
(2008)
J. Leukoc. Biol.
, vol.84
, Issue.4
, pp. 988-993
-
-
Teng, M.W.1
Swann, J.B.2
Koebel, C.M.3
Schreiber, R.D.4
Smyth, M.J.5
-
124
-
-
36849010167
-
Adaptive immunity maintains occult cancer in an equilibrium state
-
DOI 10.1038/nature06309, PII NATURE06309
-
Koebel CM, Vermi W, Swann JB et al.: Adaptive immunity maintains occult cancer in an equilibrium state. Nature 450(7171), 903-907 (2007). ■■ First experimental proof of tumor dormancy in vivo. (Pubitemid 350231320)
-
(2007)
Nature
, vol.450
, Issue.7171
, pp. 903-907
-
-
Koebel, C.M.1
Vermi, W.2
Swann, J.B.3
Zerafa, N.4
Rodig, S.J.5
Old, L.J.6
Smyth, M.J.7
Schreiber, R.D.8
-
125
-
-
0032529225
-
Initial cytokine exposure determines function of macrophages and renders them unresponsive to other cytokines
-
Erwig LP, Kluth DC, Walsh GM, Rees AJ: Initial cytokine exposure determines function of macrophages and renders them unresponsive to other cytokines. J. Immunol. 161(4), 1983-1988 (1998).
-
(1983)
J. Immunol.
, vol.161
, Issue.4
, pp. 1998
-
-
Erwig, L.P.1
Kluth, D.C.2
Walsh, G.M.3
Rees, A.J.4
-
126
-
-
0034790277
-
Suppression by apoptotic cells defines tumor necrosis factor-mediated induction of glomerular mesangial cell apoptosis by activated macrophages
-
Duffield JS, Ware CF, Ryffel B, Savill J: Suppression by apoptotic cells defines tumor necrosis factor-mediated induction of glomerular mesangial cell apoptosis by activated macrophages. Am. J. Pathol. 159(4), 1397-1404 (2001).
-
(2001)
Am. J. Pathol.
, vol.159
, Issue.4
, pp. 1397-1404
-
-
Duffield, J.S.1
Ware, C.F.2
Ryffel, B.3
Savill, J.4
-
127
-
-
28544446111
-
Monocyte and macrophage heterogeneity
-
Gordon S, Taylor PR: Monocyte and macrophage heterogeneity. Nat. Rev. Immunol. 5(12), 953-964 (2005).
-
(2005)
Nat. Rev. Immunol.
, vol.5
, Issue.12
, pp. 953-964
-
-
Gordon, S.1
Taylor, P.R.2
|