ADAM8: A new therapeutic target for asthma

Expert Opinion on Therapeutic Targets

Volumn 13, Issue 5, 2009, Pages 523-540

  Knolle, Martin D ^a   Owen, Caroline A ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

ADAM; Airway hyper responsiveness; Allergy; Asthma; Disintegrin; Eosinophil; Epithelium; Inflammation; Leukocyte; Macrophage; Metalloproteinase; Proteinase; Remodeling; Signaling

Indexed keywords

A DISINTEGRIN AND METALLOPROTEASE DOMAIN 8; ADAM PROTEIN; BRONCHODILATING AGENT; CELL ADHESION MOLECULE; CORTICOSTEROID; CYSTEINE; CYTOKINE; CYTOKINE RECEPTOR; DISINTEGRIN; EPIDERMAL GROWTH FACTOR; LEUKOCYTE ANTIGEN; PROTEINASE; UNCLASSIFIED DRUG;

ALLERGIC ASTHMA; ATOPY; CELL ACTIVATION; CELL HYPERPLASIA; CHROMOSOME; CYTOPLASM; ECONOMIC EVALUATION; HEALTH CARE; HUMAN; INFLAMMATORY CELL; INFORMATION RETRIEVAL; LUNG; MYOFIBROBLAST; NONHUMAN; PATHOGENESIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN POLYMORPHISM; PROTEIN STRUCTURE; PROTEIN TARGETING; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT INFLAMMATION; REVIEW; TISSUE LEVEL; TRANSGENIC MOUSE;

ADAM PROTEINS; ANIMALS; ANTI-ASTHMATIC AGENTS; ANTIGENS, CD; ASTHMA; CHILD; CYTOKINES; DRUG DELIVERY SYSTEMS; DRUG EVALUATION, PRECLINICAL; EPITHELIAL CELLS; EXTRACELLULAR MATRIX PROTEINS; FIBROSIS; HUMANS; LEUKOCYTES; LUNG; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PROTEASE INHIBITORS; PROTEIN STRUCTURE, TERTIARY; PULMONARY EOSINOPHILIA; RECEPTORS, CELL SURFACE;

EID: 67649598621     PISSN: 14728222     EISSN: None     Source Type: Journal    
DOI: 10.1517/14728220902889788     Document Type: Review

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