Claspin is involved in S-phase checkpoint induced by benzo(a)pyrene in 16HBE cells

Toxicology in Vitro

Volumn 23, Issue 5, 2009, Pages 880-886

  Qi, Yanmin ^a   Zhao, Peng ^a   Fu, Juanling ^a   Yao, Biyun ^a   Yuan, Zhun ^a   Hu, Entan ^a   Zhou, Zongcan ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Benzo(a)pyrene (BaP); Cell cycle; Claspin; S phase checkpoint

Indexed keywords

BENZO[A]PYRENE; CARCINOGEN; CELL CYCLE PROTEIN; CHECKPOINT KINASE 1; CLASPIN; HYDROXYUREA; PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CARCINOGEN DNA INTERACTION; CELL CYCLE ARREST; CELL CYCLE S PHASE; CELL STRESS; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENOTOXICITY; HUMAN; HUMAN CELL; INFRARED RADIATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; ULTRAVIOLET RADIATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BENZO(A)PYRENE; BRONCHI; CARCINOGENS, ENVIRONMENTAL; CELL LINE; DNA DAMAGE; EPITHELIAL CELLS; HUMANS; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; S PHASE; TIME FACTORS;

EID: 67649363287     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2009.05.006     Document Type: Article

References (41)

1. Abraham R.T. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes and Development 15 (2001) 2177-2196
2. Brandon D.J., Eddy J.C., Jean M.G., and Donato F.R. Disruption of cell cycle kinetics by benzo[a]pyrene: inverse expression patterns of BRCA-1 and p53 in MCF-7 cells arrested in S and G2. Neoplasia 2 (2000) 460-470
3. Brondello J.M., Ducommun B., Fernandez A., and Lamb N.J. Linking PCNA-dependent replication and ATR by human Claspin. Biochemical and Biophysical Research Communications 354 (2007) 1028-1033
4. Caino C., Oliva J.L., Jiang H., Penning T.M., and Kazanietz M.G. Benzo[a]pyrene-7,8-dihydrodiol promotes checkpoint activation and G2/M arrest in human bronchoalveolar carcinoma H358 cells. Molecular Pharmacology 71 (2007) 744-750
5. Chini C.C., and Chen J. Human Claspin is required for replication checkpoint control. The Journal of Biological Chemistry 278 (2003) 30057-30062
6. Dipple A., Khan Q.A., Page J.E., Pontén I., and Szeliga J. DNA reactions, mutagenic action and stealth properties of polycyclic aromatic hydrocarbon carcinogens. International Journal of Oncology 14 (1999) 103-111
7. Donzelli M., and Draetta G.F. Regulating mammalian checkpoints through Cdc25 inactivation. EMBO Reports 4 (2003) 671-677
8. Guo N., Vaziri C., and Faller D.V. A novel DNA damage checkpoint involving post-transcriptional regulation of cyclin A expression. The Journal of Biological Chemistry 275 (2000) 1715-1722
9. Guo N., Faller D.V., and Vaziri C. Carcinogen-induced S-phase arrest is Chk1 mediated and caffeine sensitive. Cell Growth and Differentiation 13 (2002) 77-86
10. Heffernan T.P., Simpson D.A., Frank A.R., Heinloth A.N., Paules R.S., Cordeiro-Stone M., and Kaufmann W.K. An ATR- and Chk1-dependent S checkpoint inhibits replicon initiation following UVC-induced DNA damage. Molecular and Cellular Biology 22 (2002) 8552-8561
11. Jeffy B.D., Chen E.J., Gudas J.M., and Romagnolo D.F. Disruption of cell cycle kinetics by benzo[a]pyrene: inverse expression patterns of BRCA-1 and p53 in MCF-7 cells arrested in S and G2. Neoplasia 2 (2000) 460-470
12. Jeong S.Y., Kumagai A., Lee J., and Dunphy W.G. Phosphorylated Claspin interacts with a phosphate-binding site in the kinase domain of Chk1 during ATR-mediated activation. The Journal of Biological Chemistry 278 (2003) 46782-46788
13. Khan Q.A., and Dipple A. Diverse chemical carcinogens fail to induce G1 arrest in MCF-7 cells. Carcinogenesis 21 (2000) 1611-1618
14. Kumagai A., and Dunphy W.G. Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts. Molecular Cell 6 (2000) 839-849
15. Lengauer C., Kinzler K.W., and Vogelstein B. Genetic instabilities in human cancers. Nature 396 (1998) 643-649
16. Lin S.Y., Li K., Stewart G.S., and Elledge S.J. Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation. Proceedings of the National Academy of Sciences of the United States of America 101 (2004) 6484-6489
17. Liu P., Barkley L.R., Day T., Bi X., Slater D.M., Alexandrow M.G., Nasheuer H.P., and Vaziri C. The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2- independent mechanism. The Journal of Biological Chemistry 281 (2006) 30631-30644
18. Loeb K.R., and Loeb L.A. Significance of multiple mutations in cancer. Carcinogenesis 21 (2000) 379-385
19. Mailand N., Bekker-Jensen S., Bartek J., and Lukas J. Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress. Molecular Cell 23 (2006) 307-318
20. Mamely I., van Vugt M.A., Smits V.A., Semple J.I., Lemmens B., Perrakis A., Medema R.H., and Freire R. Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery. Current Biology 16 (2006) 1950-1955
21. Mastrangelo G., Fadda E., and Marzia V. Polycyclic aromatic hydrocarbons and cancer in man. Environmental Health Perspectives 104 (1996) 1166-1170
22. Matsuoka S., Huang M., and Elledge S.J. Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science 282 (1998) 1893-1897
23. Melo J., and Toczyski D. A unified view of the DNA-damage checkpoint. Current Opinion in Cell Biology 14 (2002) 237-245
24. Niida H., and Nakanishi M. DNA damage checkpoints in mammals. Mutagenesis 21 (2006) 3-9
25. Paulovich A.G., Toczyski D.P., and Hartwell L.H. When checkpoints fail. Cell 88 (1997) 315-321
26. Peschiaroli A., Dorrello N.V., Guardavaccaro D., Venere M., Halazonetis T., Sherman N.E., and Pagano M. SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response. Molecular Cell 23 (2006) 319-329
27. Samuel T., Weber H.O., and Funk J.O. Linking DNA damage to cell cycle checkpoints. Cell Cycle 1 (2002) 162-168
28. Sancar A., Lindsey-Boltz L.A., Unsal-Kaçmaz K., and Linn S. Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annual Review of Biochemistry 73 (2004) 39-85
29. Sanchez Y., Wong C., Thoma R.S., Richman R., Wu Z., Piwnica-Worms H., and Elledge S.J. Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. Science 277 (1997) 1497-1501
30. Sar F., Lindsey-Boltz L.A., Subramanian D., Croteau D.L., Hutsell S.Q., Griffith J.D., and Sancar A. Human Claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures. The Journal of Biological Chemistry 279 (2004) 39289-39295
31. Sørensen C.S., Syljuasen R.G., Lukas J., and Bartek J. ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage. Cell Cycle 3 (2004) 941-945
32. Wang A., Gu J., Kremer J.K., Powell K.L., Mistry H., Simhambhatla P., Aldaz C.M., Gaddis S., and MacLeod M.C. Response of human mammary epithelial cells to DNA damage induced by BPDE: involvement of novel regulatory pathways. Carcinogenesis 24 (2003) 225-234
33. Weiss R., Leder S.P., and Vaziri C. Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint. Molecular and Cellular Biology 23 (2003) 791-803
34. Xiao Z., Chen Z., Gunasekera A.H., Sowin T.J., Rosenberg S.H., Fesik S., and Zhang H. Chk1 mediates S and G2 arrests through Cdc25A degradation in response to DNA-damaging agents. The Journal of Biological Chemistry 278 (2003) 21767-21773
35. Yamane K., Wu X., and Chen J. A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival. Molecular and Cellular Biology 22 (2002) 555-566
36. Yao B., Fu J., Hu E., Qi Y., and Zhou Z. The Cdc25A is involved in S-phase checkpoint induced by benzo(a)pyrene. Toxicology 237 (2007) 210-217
37. Yao B., Fu J., Hu E., Qi Y., and Zhou Z. The effects of over-expression and suppression of Cdc25A on the S-phase checkpoint induced by benzo(a)pyrene. Toxicology 246 (2008) 180-187
38. Zhang D., Zaugg K., Mak T.W., and Elledge S.J. A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response. Cell 126 (2006) 529-542
39. Zhao H., and Russell P. DNA binding domain in the replication checkpoint protein Mrc1 of Schizosaccharomyces pombe. The Journal of Biological Chemistry 279 (2004) 53023-53027
40. Zhou B.B., and Bartek J. Targeting the checkpoint kinases: chemosensitization versus chemoprotection. Nature Reviews Cancer 4 (2004) 216-225
41. Zhou B.B., and Elledge S.J. The DNA damage response: putting checkpoints in perspective. Nature 408 (2000) 433-439