Systemic effects in COPD

Chest

Volumn 121, Issue 5 SUPPL., 2002, Pages 127S-130S

  Wouters, Emil F M ^a   Creutzberg, Eva C ^a   Schols, Annemie M W J ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Body weight; COPD; Fat free mass; Muscle protein catabolism; Prognosis; Systemic effects; Systemic inflammation; Tumor necrosis factor

Indexed keywords

ACUTE PHASE PROTEIN; CELL ADHESION MOLECULE; GAMMA INTERFERON; GLUCOCORTICOID; GROWTH HORMONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; INTERLEUKIN 1; MUSCLE PROTEIN; TESTOSTERONE; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA;

BODY FAT; BREATHING MUSCLE; CACHEXIA; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL FEATURE; CONFERENCE PAPER; DISEASE EXACERBATION; HORMONAL REGULATION; HUMAN; INFLAMMATION; MUSCLE ATROPHY; OXIDATIVE STRESS; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; SYSTEMIC DISEASE; WEIGHT REDUCTION;

EID: 0036264584     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.121.5_suppl.127S     Document Type: Conference Paper

References (33)

1. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary
2. Systemic oxidative stress in asthma, COPD, and smokers
3. Evidence for a relation between metabolic derangements and increased levels of inflammatory mediators in a subgroup of patients with chronic obstructive pulmonary disease
4. Circulating leptin in patients with chronic obstructive pulmonary disease
5. Expression of adhesion molecules and G proteins in circulating neutrophils in chronic obstructive pulmonary disease
6. Circulating cell adhesion molecules in bronchial lavage and serum in COPD patients with chronic bronchitis
7. Nutritional depletion in relation to respiratory and peripheral skeletal muscle function in out-patients with COPD
8. Prevalence and characteristics of nutritional depletion in patients with stable COPD eligible for pulmonary rehabilitation
9. Peak exercise response in relation to tissue depletion in patients with chronic obstructive pulmonary disease
10. Nutritional state and exercise tolerance in patients with COPD
11. Skeletal muscle weakness is associated with wasting of extremity fat-free mass but not with airflow obstruction in patients with chronic obstructive pulmonary disease
12. Effect of reduced body weight on muscle aerobic capacity in patients with COPD
13. Tissue depletion and health related quality of life in patients with chronic obstructive pulmonary disease
14. Weight loss is a reversible factor in the prognosis of chronic obstructive pulmonary disease
15. Prognostic value of nutritional status in chronic obstructive pulmonary disease
16. Enhanced levels of whole-body protein turnover in patients with chronic obstructive pulmonary disease
17. Growth hormone therapy for protein catabolism
18. Amrinone prevents muscle protein wasting during chronic sepsis
19. Transient exposure of human myoblasts to tumor necrosis factor-α inhibits serum and insulin-like growth factor-I stimulated protein synthesis
20. Anabolic steroids
21. Testosterone levels in men with chronic obstructive pulmonary disease with or without glucocorticoid therapy
22. Muscle fiber type IIX atrophy is involved in the loss of fat-free mass in chronic obstructive pulmonary disease
23. Morphologic features of the myopathy associated with chronic renal failure
24. Skeletal muscle studies in patients with HIV-related wasting syndrome
25. Altered expression of myosin heavy chain in human skeletal muscle in chronic heart failure
26. Tumor necrosis factor-α levels and weight loss in chronic obstructive pulmonary disease
27. Elevated TNF-α production by peripheral blood monocytes of weight-losing COPD patients
28. Mechanisms of muscle wasting: The role of the ubiquitin-proteasome pathway
29. What do we really know about the ubiquitin-proteasome pathway in muscle atrophy?
30. Skeletal muscle myocytes undergo protein loss and reactive oxygen-mediated NF-κB activation in response to tumor necrosis factor alpha
31. MyoD protein accumulates in satellite cells and is neurally regulated in regenerating myotubes and skeletal muscle fibers
32. NF-κB-induced loss of MyoD messenger RNA: Possible role in muscle decay and cachexia
33. Inflammatory cytokines inhibit myogenic differentiation through activation of nuclear factor-κB