Synthesis and copper-mediated nuclease activity of a tetracationic tris(2,2′-bipyridine) ligand

Journal of Inorganic Biochemistry

Volumn 103, Issue 7, 2009, Pages 1067-1073

  Arias, María Selma ^a   González Álvarez, Marta ^b   Fernández, María José ^a   Lorente, Antonio ^a   Alzuet, Gloria ^b   Borrás, Joaquín ^b  

^a UNIVERSITY OF ALCALÁ   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Copper(II) complexes; DNA binding; Oxidative DNA damage; Tetracationic tris(2,2 bipyridine) ligand

Indexed keywords

5,5' BIS[DIMETHYL[2 [DIMETHYL[(5' METHYL 2,2' BIPYRIDIN 5 YL)METHYL]AMMONIO]AMMONIO]METHYL] 2,2' BIPYRIDINYLTETRABROMIDE COPPER; COPPER COMPLEX; HYDROGEN PEROXIDE; HYDROXYL RADICAL; PLASMID DNA; SINGLET OXYGEN; SUPEROXIDE; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DNA CLEAVAGE; DNA STRAND BREAKAGE; DRUG BINDING SITE; DRUG DESIGN; DRUG DNA BINDING; DRUG POTENCY; DRUG SYNTHESIS; INTERCALATION COMPLEX; MOLECULAR STABILITY;

2,2'-DIPYRIDYL; ANIMALS; COPPER; DEOXYRIBONUCLEASES; DNA; DNA CLEAVAGE; LIGANDS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 67449143481     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2009.05.003     Document Type: Article

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