Direct binding to Rsp5p regulates ubiquitination-independent vacuolar transport of Sna3p

Molecular Biology of the Cell

Volumn 18, Issue 5, 2007, Pages 1781-1789

  Watson, Hadiya ^a   Bonifacino, Juan S ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; BSD2P PROTEIN; CARBOXYPEPTIDASE; CARBOXYPEPTIDASE S; MEMBRANE PROTEIN; PROTEIN DERIVATIVE; RSP5P PROTEIN; SNA3P PROTEIN; TUL1P PROTEIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ARTICLE; CELL VACUOLE; ENZYME ACTIVITY; ENZYME REGULATION; MEMBRANE VESICLE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN TARGETING; PROTEIN TRANSPORT; UBIQUITINATION;

AMINO ACID SEQUENCE; BINDING SITES; BIOLOGICAL TRANSPORT, ACTIVE; CARBOXYPEPTIDASES; GENES, FUNGAL; GREEN FLUORESCENT PROTEINS; MEMBRANE PROTEINS; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE DELETION; UBIQUITIN; UBIQUITIN-PROTEIN LIGASE COMPLEXES; VACUOLES;

SACCHAROMYCES CEREVISIAE;

EID: 34248162393     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E06-10-0887     Document Type: Article

References (32)

1. Babst, M. (2005). A protein's final ESCRT. Traffic 6, 2-9.
2. Bedford, M. T., Chan, D. C., and Leder, P. (1997). FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands. EMBO J. 16, 2376-2383.
3. Benedetti, H., Raths, S., Crausaz, F., and Riezman, H. (1994). The END3 gene encodes a protein that is required for the internalization step of endocytosis and for actin cytoskeleton organization in yeast. Mol. Biol. Cell 5, 1023-1037.
4. Bilodeau, P. S., Urbanowski, J. L., Winistrofer, S. C., and Piper, R. C. (2002). The Vps27p Hse1p complex binds ubiquitin and mediates endosomal protein sorting. Nat. Cell Biol. 4, 534-539.
5. Bonangelino, C. J., Chavez, E. M., and Bonifacino, J. (2002). Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae. Mol. Biol. Cell 13, 2486-2501.
6. Dunn, R., and Hicke, L. (2001a). Domains of the Rsp5 ubiquitin-protein ligase required for receptor-mediated and fluid-phase endocytosis. Mol. Biol. Cell 12, 421-435.
7. Dunn, R., and Hicke, L. (2001b). Multiple roles for Rsp5p-dependent ubiquitination at the internalization step of endocytosis. J. Biol. Chem. 276, 25974-25981.
8. Gajewska, B., Kaminka, J., Jesionowska, A., Martin, N. C., Hopper, A. K., and Zoladek, T. (2001). WW domains of Rsp5p define different functions: determination of roles in fluid phase and uracil permease endocytosis in Saccharomyces cerevisiae. Genetics 157, 91-101.
9. Harty, R. N., Brown, M. E., Wang, G., Huibregtse, J., and Hayes, F. P. (2000). APPxY motif within the VP40 protein of Ebola virus interacts physically and functionally with a ubiquitin ligase: implications for filovirus budding. Proc. Natl. Acad. Sd. USA 97, 13871-13876.
10. Hettema, E. H., Valdez-Taubas, J., and Pelham, H. R. (2004). Bsd2 binds the ubiquitin ligase Rsp5 and mediates the ubiquitination of transmembrane proteins. EMBO J. 23, 1279-1288.
11. Hicke, L., and Dunn, R. (2003). Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins. Annu. Rev. Cell Dev. Biol. 19, 141-172.
12. Hurley, J., and Emr, S. D. (2006). The ESCRT complexes: structure and mechanism of a membrane-trafficking network. Annu. Rev. Biophys. Biomol. Struct. 35, 277-289.
13. Kaminka, J., Gajewska, B., Hopper, A. K., and Zoladek, T. (2002). Rsp5p, a new link between the actin cytoskeleton and endocytosis in the yeast Saccharomyces cerevisiae. Mol. Cell. Biol. 22, 6946-6948.
14. Katzmann, D. J., Babst, M., and Emr, S. D. (2001). Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell 106, 145-155.
15. Katzmann, D. J., Odorizzi, G., and Emr, S. D. (2002). Receptor downregulation and multivesicular-body sorting. Nat. Rev. Mol. Cell Biol. 3, 893-905.
16. Katzmann, D. J., Sarkar, S., Chu, T., Audhya, A., and Emr, S. D. (2004). Multivesicular body sorting: ubiquitin ligase Rsp5 is required for the modification and sorting of carboxypeptidase S. Mol. Biol. Cell 15, 468-480.
17. McNatt, M. W., McKittrick, I., West, M., and Odorizzi, G. (2006). Direct binding to Rsp5 mediates ubiquitin-independent sorting of Sna3 via the multivesicular body pathway. Mol. Biol. Cell 18, 697-706.
18. Morvan, J., Froissard, M., Haguenauer-Tsapis, R., and Urban-Grimal, D. (2004). The ubiquitin ligase Rsp5p is required for modification and sorting of membrane proteins into multivesicular bodies. Traffic 5, 383-392.
19. Odorizzi, G., Babst, M., and Emr, S. D. (1998). Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular body. Cell 95, 847-858.
20. Oestreich, A. J., Aboian, M., Lee, J., Azmi, I., Payne, J., Issaka, R., Davies, B., and Katzmann, D. J. (2006) Characterization of multiple MVB sorting determinants within Sna3, a role for the rsp5 ubiquitin ligase. Mol. Biol. Cell 18, 707-720.
21. Peng, J. Schwartz, D., Elias, J. E., Thoreen, C. C., Cheng, D., Marsischky, G. Roelofs, J., Finley, D., and Gygi, S. P. (2003). A proteomics approach to understanding protein ubiquitination. Nat. Biotechnol. 8, 921-926.
22. Reggiori, F., Black, M. W., and Pelham, H. R. (2000). Polar transmembrane domains target proteins to the interior of the yeast vacuole. Mol. Biol. Cell 11, 3737-3749.
23. Reggiori, F., and Pelham, H. R. (2001). Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting. EMBO J. 20, 5176-5186.
24. Reggiori, F., and Pelham, H. R. (2002). A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies. Nat. Cell Biol. 4, 117-123.
25. Rieder, S. E., Banta, L. M., Kohrer, K., McCaffery, J. M., and Emr, S. D. (1996). Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutant. Mol. Biol. Cell 7, 985-999.
26. Stamenova, S. D., Dunn, R., Adler, A. S., and Hicke, L. (2004). The Rsp5 ubiquitin ligase binds to and ubiquitinates members of the yeast CIN85-endophilin complex, Sla1-Rvs167. J. Biol. Chem. 279, 16017-16025.
27. Sudol, M. (1996). Structure and function of the WW domain. Prog. Biophys. Mol. Biol. 65, 113-132.
28. Sudol, M., Chen, H. I., Bougeret, C., Eindbond, A., and Bork, P. (1995). Characterization of a novel protein-binding module - the WW domain. FEBS Lett. 369, 67-71.
29. Tong, A. H. et al. (2002). A combined experimental and computational strategy to define protein interaction networks for peptide recognition modules. Science 295, 321-324.
30. Urbanowski, J. L., and Piper, R. C. (2001). Ubiquitin sorts proteins into the intralumenal degradative compartment of the late-endosome/vacuole. Traffic 2, 622-630.
31. Wang, G., Yang, J., and Huibregtse, J. M. (1999). Functional domains of the Rsp5 ubiquitin-protein ligase. Mol. Cell. Biol. 19, 342-352.
32. Wang, G., McCaffery, J. M., Wendland, B., Dupre, S., Haguenauer-Tsapis, R., and Huibregtse, J. M. (2001). Localization of the Rsp5p ubiquitin-protein ligase at multiple sites within the endocytic pathway. Mol. Cell. Biol. 21, 3564-3575.