A designed angiopoietin-2 variant, pentameric COMP-Ang2, strongly activates Tie2 receptor and stimulates angiogenesis

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1793, Issue 5, 2009, Pages 772-780

  Kim, Hak Zoo ^a   Jung, Keehoon ^a   Kim, Ho Min ^b   Cheng, Yifan ^b   Koh, Gou Young ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Angiopoietin 2; COMP Ang1; COMP Ang2; Oligomerization; Tie2

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN 2; ANGIOPOIETIN RECEPTOR; MATRILIN 1; SCLEROPROTEIN; TRANSCRIPTION FACTOR GCN4; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANGIOGENESIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CELL MIGRATION; CELL SURVIVAL; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN VARIANT; RECEPTOR BINDING; WOUND HEALING;

ANGIOPOIETIN-1; ANGIOPOIETIN-2; CELL MOVEMENT; CELLS, CULTURED; ENDOTHELIAL CELLS; HUMANS; NEOVASCULARIZATION, PHYSIOLOGIC; PROTEIN CONFORMATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, TIE-2; RECOMBINANT FUSION PROTEINS;

EID: 67349263020     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2009.01.018     Document Type: Article

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