Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering

Nature Structural Biology

Volumn 10, Issue 1, 2003, Pages 38-44

  Davis, Samuel ^a   Papadopoulos, Nick ^a   Aldrich, Thomas H ^a   Maisonpierre, Peter C ^a   Huang, Tammy ^a   Kovac, Lubomir ^a   Xu, April ^a   Leidich, Raymond ^a   Radziejewska, Elzbieta ^a   Rafique, Ashique ^a   Goldberg, Judah ^a   Jain, Vivek ^a   Bailey, Kevin ^a   Karow, Margaret ^a   Fandl, Jim ^a   Samuelsson, Steven J ^b   Ioffe, Ella ^a   Rudge, John S ^a   Daly, Thomas J ^a   Radziejewski, Czeslaw ^a   Yancopoulos, George D ^a   more..

^a REGENERON PHARMACEUTICALS INC   (United States)

^b PROCTER AND GAMBLE PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN 2; DIMER; PROTEIN TYROSINE KINASE; RECEPTOR TIE2; TETRAMER; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DIMERIZATION; GENETIC ENGINEERING; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; RECEPTOR BINDING; STOICHIOMETRY;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANGIOPOIETIN-1; ANGIOPOIETIN-2; ANGIOPOIETINS; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; DIMERIZATION; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON, TRANSMISSION; MODELS, MOLECULAR; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN ENGINEERING; RECEPTOR, TIE-2; RECOMBINANT PROTEINS;

EID: 0037219502     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/nsb880     Document Type: Article

References (22)

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