Oligomerization and multimerization are critical for angiopoietin-1 to bind and phosphorylate Tie2

Journal of Biological Chemistry

Volumn 280, Issue 20, 2005, Pages 20126-20131

  Kim, Kyung Tae ^a   Choi, Han Ho ^a   Steinmetz, Michel O ^b   Maco, Bohumil ^c   Kammerer, Richard A ^d   Ahn, So Young ^a   Kim, Hak Zoo ^a   Lee, Gyun Min ^a   Koh, Gou Young ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b PAUL SCHERRER INSTITUTE   (Switzerland)

^c UNIVERSITY OF BASEL   (Switzerland)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BLOOD VESSELS; OLIGOMERS; TRANSMISSION ELECTRON MICROSCOPY;

HOMOLOGY; MULTIMERIZATION; OLIGOMERIZATION; ROTATORY METAL SHADOWING TRANSMISSION ELECTRON MICROSCOPY (RMSTEM);

PROTEINS;

ANGIOPOIETIN 1; ANGIOPOIETIN 2; ANGIOPOIETIN RECEPTOR; CYSTEINE; DIMER; OLIGOMER; RECEPTOR SUBUNIT; SERINE; ANGPT1 PROTEIN, HUMAN; RECOMBINANT PROTEIN;

AMINO ACID SUBSTITUTION; ANGIOGENESIS; ARTICLE; BINDING AFFINITY; DISULFIDE BOND; HUMAN; HUMAN CELL; OLIGOMERIZATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; RECEPTOR UPREGULATION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; CELL LINE; CELL STRAIN 3T3; CHEMISTRY; COMPARATIVE STUDY; ELECTRON MICROSCOPY; ENZYME ACTIVATION; GENETIC VARIABILITY; GENETICS; METABOLISM; MOUSE; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN QUATERNARY STRUCTURE;

3T3-L1 CELLS; ANGIOPOIETIN-1; ANGIOPOIETIN-2; ANIMALS; CELL LINE; CYSTEINE; ENZYME ACTIVATION; HUMANS; MICE; MICROSCOPY, ELECTRON; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; RECEPTOR, TIE-2; RECOMBINANT PROTEINS; VARIATION (GENETICS);

EID: 21244434808     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M500292200     Document Type: Article

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