-
1
-
-
0017184389
-
Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford, M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254; 1976.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
2
-
-
33646780950
-
Signaling and functions of Angiopoietin-1 in vascular protection
-
Brindle, N. P. J.; Saharinen, P.; Alitalo, K. Signaling and functions of Angiopoietin-1 in vascular protection. Circ. Res. 98:1014-1023; 2006.
-
(2006)
Circ. Res.
, vol.98
, pp. 1014-1023
-
-
Brindle, N.P.J.1
Saharinen, P.2
Alitalo, K.3
-
3
-
-
11144357304
-
COMP-Ang1: A designed angiopoietin-1 variant with nonleaky angiogenic activity
-
Cho, C. H.; Kammerer, R. A.; Lee, H. J.; Steinmetz, M. O.; Ryu, Y. S.; Lee, S. H.; Yasunaga, K.; Kim, K. T.; Kim, I.; Choi, H. H.; Kim, W.; Kim, S. H.; Park, S. K.; Lee, G. M.; Koh, G. Y. COMP-Ang1: a designed angiopoietin-1 variant with nonleaky angiogenic activity. Proc. Natl. Acad. Sci. USA 101:5547-5552; 2004.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 5547-5552
-
-
Cho, C.H.1
Kammerer, R.A.2
Lee, H.J.3
Steinmetz, M.O.4
Ryu, Y.S.5
Lee, S.H.6
Yasunaga, K.7
Kim, K.T.8
Kim, I.9
Choi, H.H.10
Kim, W.11
Kim, S.H.12
Park, S.K.13
Lee, G.M.14
Koh, G.Y.15
-
4
-
-
0030460424
-
Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning
-
Davis, S.; Aldrich, T. H.; Jones, P. F.; Acheson, A.; Compton, D. L.; Jain, V.; Ryan, T. E.; Bruno, J.; Radziejewski, C.; Maisonpierre, P. C.; Yancopoulos, G. D. Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning. Cell 87:1161-1169; 1996.
-
(1996)
Cell
, vol.87
, pp. 1161-1169
-
-
Davis, S.1
Aldrich, T.H.2
Jones, P.F.3
Acheson, A.4
Compton, D.L.5
Jain, V.6
Ryan, T.E.7
Bruno, J.8
Radziejewski, C.9
Maisonpierre, P.C.10
Yancopoulos, G.D.11
-
5
-
-
0037219502
-
Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering
-
Davis, S.; Papadopoulos, N.; Aldrich, T. H.; Maisonpierre, P. C.; Huang, T.; Kovac, L.; Xu, A.; Leidich, R.; Radziejewska, E.; Rafique, A.; Goldberg, J.; Jain, V.; Bailey, K.; Karow, M.; Fandl, J.; Samuelsson, S. J.; Ioffe, E.; Rudge, J. S.; Daly, T. J.; Radziejewski, C.; Yancopoulos, G. D. Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering. Nat. Struct. Biol. 10:38-44; 2003.
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 38-44
-
-
Davis, S.1
Papadopoulos, N.2
Aldrich, T.H.3
Maisonpierre, P.C.4
Huang, T.5
Kovac, L.6
Xu, A.7
Leidich, R.8
Radziejewska, E.9
Rafique, A.10
Goldberg, J.11
Jain, V.12
Bailey, K.13
Karow, M.14
Fandl, J.15
Samuelsson, S.J.16
Ioffe, E.17
Rudge, J.S.18
Daly, T.J.19
Radziejewski, C.20
Yancopoulos, G.D.21
more..
-
6
-
-
0037449763
-
Angiopoietin-1 and angiopoietin-2 share the same binding domains in the Tie-2 receptor involving the first Ig-like loop and the epidermal growth factor-like repeats
-
Fiedler, U.; Krissl, T.; Koidl, S.; Weiss, C.; Koblizek, T.; Deutsch, U.; Martiny-Baron, G.; Marme, D.; Augustin, H. G. Angiopoietin-1 and angiopoietin-2 share the same binding domains in the Tie-2 receptor involving the first Ig-like loop and the epidermal growth factor-like repeats. J. Biol. Chem. 278:1721-1727; 2003.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1721-1727
-
-
Fiedler, U.1
Krissl, T.2
Koidl, S.3
Weiss, C.4
Koblizek, T.5
Deutsch, U.6
Martiny-Baron, G.7
Marme, D.8
Augustin, H.G.9
-
7
-
-
13444302796
-
Oligomerization state-dependent hyperlipidemic effect of angiopoietin-like protein 4
-
Ge, H.; Yang, G.; Yu, X.; Pourbahrami, T.; Li, C. Oligomerization state-dependent hyperlipidemic effect of angiopoietin-like protein 4. J. Lipid Res. 45:2071-2079; 2004.
-
(2004)
J. Lipid Res.
, vol.45
, pp. 2071-2079
-
-
Ge, H.1
Yang, G.2
Yu, X.3
Pourbahrami, T.4
Li, C.5
-
8
-
-
0025840338
-
The oligosaccharides of glycoproteins: Bioprocess factors affecting oligosaccharide structure and their effect on glycoprotein properties
-
Goochee, C. F.; Gramer, M. J.; Andersen, D. C.; Bahr, J. B.; Rasmussen, J. R. The oligosaccharides of glycoproteins: bioprocess factors affecting oligosaccharide structure and their effect on glycoprotein properties. Biotechnology 9:1347-1355; 1991.
-
(1991)
Biotechnology
, vol.9
, pp. 1347-1355
-
-
Goochee, C.F.1
Gramer, M.J.2
Andersen, D.C.3
Bahr, J.B.4
Rasmussen, J.R.5
-
9
-
-
1942455227
-
A pericyte-derived angiopoietin-1 multimeric complex induces occludin gene expression in brain capillary endothelial cells through Tie-2 activation in vitro
-
Hori, S.; Ohtsuki, S.; Hosoya, K.; Nakashima, E.; Terasaki, T. A pericyte-derived angiopoietin-1 multimeric complex induces occludin gene expression in brain capillary endothelial cells through Tie-2 activation in vitro. J. Neurochem. 89:503-513; 2004.
-
(2004)
J. Neurochem.
, vol.89
, pp. 503-513
-
-
Hori, S.1
Ohtsuki, S.2
Hosoya, K.3
Nakashima, E.4
Terasaki, T.5
-
10
-
-
11844287623
-
Expression and purification of recombinant human angiopoietin-2 produced in Chinese hamster ovary cells
-
Hwang, S. J.; Choi, H. H.; Kim, K. T.; Hong, H. J.; Koh, G. Y.; Lee, G. M. Expression and purification of recombinant human angiopoietin-2 produced in Chinese hamster ovary cells. Protein Express. Purif. 39:175-183; 2005.
-
(2005)
Protein Express. Purif.
, vol.39
, pp. 175-183
-
-
Hwang, S.J.1
Choi, H.H.2
Kim, K.T.3
Hong, H.J.4
Koh, G.Y.5
Lee, G.M.6
-
11
-
-
0025268959
-
Physicochemical and biological comparison of recombinant human erythropoietin with human urinary erythropoietin
-
Imai, N.; Kawamura, A.; Higuchi, M.; Oh-eda, M.; Orita, T.; Kawaguchi, T.; Ochi, N. Physicochemical and biological comparison of recombinant human erythropoietin with human urinary erythropoietin. J. Biochem. 107:352-359; 1990.
-
(1990)
J. Biochem.
, vol.107
, pp. 352-359
-
-
Imai, N.1
Kawamura, A.2
Higuchi, M.3
Oh-Eda, M.4
Orita, T.5
Kawaguchi, T.6
Ochi, N.7
-
12
-
-
0029065680
-
N-glycosylation of recombinant human interferon-gamma produced in different animal expression systems
-
James, D. C.; Freedman, R. B.; Hoare, M.; Ogonah, O. W.; Rooney, B. C.; Larionov, O. A.; Dobrovolsky, V. N.; Lagutin, O. V.; Jenkins, N. N-glycosylation of recombinant human interferon-gamma produced in different animal expression systems. Biotechnology 13:592-596; 1995.
-
(1995)
Biotechnology
, vol.13
, pp. 592-596
-
-
James, D.C.1
Freedman, R.B.2
Hoare, M.3
Ogonah, O.W.4
Rooney, B.C.5
Larionov, O.A.6
Dobrovolsky, V.N.7
Lagutin, O.V.8
Jenkins, N.9
-
13
-
-
0036095059
-
Suppression of diabetic retinopathy with angiopoietin-1
-
Joussen, A. M.; Poulaki, V.; Tsujikawa, A.; Qin, W.; Qaum, T.; Xu, Q.; Moromizato, Y.; Bursell, S. E.; Wiegand, S. J.; Rudge, J.; Ioffe, E.; Yancopoulos, G. D.; Adamis, A. P. Suppression of diabetic retinopathy with angiopoietin-1. Am. J. Pathol. 160:1683-1693; 2002.
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 1683-1693
-
-
Joussen, A.M.1
Poulaki, V.2
Tsujikawa, A.3
Qin, W.4
Qaum, T.5
Xu, Q.6
Moromizato, Y.7
Bursell, S.E.8
Wiegand, S.J.9
Rudge, J.10
Ioffe, E.11
Yancopoulos, G.D.12
Adamis, A.P.13
-
14
-
-
0002598959
-
Characterization of chimeric antibody producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure
-
Kim, S. J.; Kim, N. S.; Ryu, C. J.; Hong, H. J.; Lee, G. M. Characterization of chimeric antibody producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure. Biotechnol. Bioeng. 58:73-84; 1998.
-
(1998)
Biotechnol. Bioeng.
, vol.58
, pp. 73-84
-
-
Kim, S.J.1
Kim, N.S.2
Ryu, C.J.3
Hong, H.J.4
Lee, G.M.5
-
15
-
-
0006677050
-
Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway
-
Kim, I.; Kim, H. G.; So, J. N.; Kim, J. H.; Kwak, H. J.; Koh, G. Y. Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Circ. Res. 86:24-29; 2000.
-
(2000)
Circ. Res.
, vol.86
, pp. 24-29
-
-
Kim, I.1
Kim, H.G.2
So, J.N.3
Kim, J.H.4
Kwak, H.J.5
Koh, G.Y.6
-
16
-
-
0035860845
-
Angiopoietin-1 reduces VEGF-stimulated leukocyte adhesion to endothelial cells by reducing ICAM-1, VCAM-1, and E-selectin expression
-
Kim, I.; Moon, S. O.; Park, S. K.; Chae, S. W.; Koh, G. Y. Angiopoietin-1 reduces VEGF-stimulated leukocyte adhesion to endothelial cells by reducing ICAM-1, VCAM-1, and E-selectin expression. Circ. Res. 89:477-479; 2001a.
-
(2001)
Circ. Res.
, vol.89
, pp. 477-479
-
-
Kim, I.1
Moon, S.O.2
Park, S.K.3
Chae, S.W.4
Koh, G.Y.5
-
17
-
-
0000608175
-
Relationship between cell size and specific thrombopoietin productivity in Chinese hamster ovary cells during dihydrofolate reductase-mediated gene amplification
-
Kim, T. K.; Chung, J. Y.; Sung, Y. H.; Lee, G. M. Relationship between cell size and specific thrombopoietin productivity in Chinese hamster ovary cells during dihydrofolate reductase-mediated gene amplification. Biotechnol. Bioprocess Eng. 6:332-336; 2001b.
-
(2001)
Biotechnol. Bioprocess Eng.
, vol.6
, pp. 332-336
-
-
Kim, T.K.1
Chung, J.Y.2
Sung, Y.H.3
Lee, G.M.4
-
18
-
-
0035113138
-
The angiopoietin-tie2 system in coronary artery endothelium prevents oxidized low-density lipoprotein-induced apoptosis
-
Kim, I.; Moon, S. O.; Han, C. Y.; Park, Y. K.; Moon, S. K.; Kim, J. J.; Koh, G. Y. The angiopoietin-tie2 system in coronary artery endothelium prevents oxidized low-density lipoprotein-induced apoptosis. Cardiovasc. Res. 49:872-881; 2001c.
-
(2001)
Cardiovasc. Res.
, vol.49
, pp. 872-881
-
-
Kim, I.1
Moon, S.O.2
Han, C.Y.3
Park, Y.K.4
Moon, S.K.5
Kim, J.J.6
Koh, G.Y.7
-
19
-
-
21244434808
-
Oligomerization and multimerization are critical for angiopoietin-1 to bind and phosphorylate Tie2
-
Kim, K. T.; Choi, H. H.; Steinmetz, M. O.; Maco, B.; Kammerer, R. A.; Ahn, S. Y.; Kim, H. Z.; Lee, G. M.; Koh, G. Y. Oligomerization and multimerization are critical for angiopoietin-1 to bind and phosphorylate Tie2. J. Biol. Chem. 280:20126-20131; 2005.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 20126-20131
-
-
Kim, K.T.1
Choi, H.H.2
Steinmetz, M.O.3
MacO, B.4
Kammerer, R.A.5
Ahn, S.Y.6
Kim, H.Z.7
Lee, G.M.8
Koh, G.Y.9
-
20
-
-
15144358851
-
Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
-
Maisonpierre, P. C.; Suri, C.; Jones, P. F.; Bartunkova, S.; Wiegand, S. J.; Radziejewski, C.; Compton, D.; McClain, J.; Aldrich, T. H.; Papadopoulos, N.; Daly, T. J.; Davis, S.; Sato, T. N.; Yancopoulos, G. D. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 277:55-60; 1997.
-
(1997)
Science
, vol.277
, pp. 55-60
-
-
Maisonpierre, P.C.1
Suri, C.2
Jones, P.F.3
Bartunkova, S.4
Wiegand, S.J.5
Radziejewski, C.6
Compton, D.7
McClain, J.8
Aldrich, T.H.9
Papadopoulos, N.10
Daly, T.J.11
Davis, S.12
Sato, T.N.13
Yancopoulos, G.D.14
-
21
-
-
0035891725
-
Angiogenesis and remodeling of airway vasculature in chronic inflammation
-
McDonald, D. M. Angiogenesis and remodeling of airway vasculature in chronic inflammation. Am. J. Respir. Crit. Care Med. 164:S39-S45; 2001.
-
(2001)
Am. J. Respir. Crit. Care Med.
, vol.164
-
-
McDonald, D.M.1
-
22
-
-
0037432292
-
Angiopoietin-1 protects against the development of cardiac allograft arteriosclerosis
-
Nykanen, A. I.; Krebs, R.; Saaristo, A.; Turumen, P.; Alitalo, K.; Yla-Herttuala, S.; Koskinen, P. K.; Lemstrom, K. B. Angiopoietin-1 protects against the development of cardiac allograft arteriosclerosis. Circulation 107:1308-1314; 2003.
-
(2003)
Circulation
, vol.107
, pp. 1308-1314
-
-
Nykanen, A.I.1
Krebs, R.2
Saaristo, A.3
Turumen, P.4
Alitalo, K.5
Yla-Herttuala, S.6
Koskinen, P.K.7
Lemstrom, K.B.8
-
23
-
-
0026235117
-
Mammalian cell gene expression: Protein glycosylation
-
Parekh, R. B. Mammalian cell gene expression: protein glycosylation. Curr. Opin. Biotechnol. 2:730-734; 1991.
-
(1991)
Curr. Opin. Biotechnol.
, vol.2
, pp. 730-734
-
-
Parekh, R.B.1
-
24
-
-
16244402264
-
Angiopoietin concentrations in diabetic retinopathy
-
Patel, J. I.; Hykin, P. G.; Gregor, Z. J. Angiopoietin concentrations in diabetic retinopathy. Br. J. Ophthalmol. 89:480-483; 2005.
-
(2005)
Br. J. Ophthalmol.
, vol.89
, pp. 480-483
-
-
Patel, J.I.1
Hykin, P.G.2
Gregor, Z.J.3
-
25
-
-
0033570185
-
Angiopoietin-1 and -2 coiled coil domains mediate distinct homo-oligomerization patterns, but fibrinogen-like domains mediate ligand activity
-
Procopio, W. N.; Pelavin, P. I.; Lee, W. M.; Yeilding, N. M. Angiopoietin-1 and -2 coiled coil domains mediate distinct homo-oligomerization patterns, but fibrinogen-like domains mediate ligand activity. J. Biol. Chem. 274:30196-30201; 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 30196-30201
-
-
Procopio, W.N.1
Pelavin, P.I.2
Lee, W.M.3
Yeilding, N.M.4
-
26
-
-
0027507949
-
High-level production of recombinant immunoglobulins in mammalian cells
-
Reff, M. E. High-level production of recombinant immunoglobulins in mammalian cells. Curr. Opin. Biotechnol. 4:573-576; 1993.
-
(1993)
Curr. Opin. Biotechnol.
, vol.4
, pp. 573-576
-
-
Reff, M.E.1
-
27
-
-
0027368264
-
Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system
-
Sato, T. N.; Qin, Y.; Kozak, C. A.; Audus, K. L. Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system. Proc. Natl. Acad. Sci. U S A 90:9355-9358; 1993.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 9355-9358
-
-
Sato, T.N.1
Qin, Y.2
Kozak, C.A.3
Audus, K.L.4
-
28
-
-
0030480322
-
Requisite role of angiopoietin-1, a ligand for the TIE2 Receptor, during embryonic angiogenesis
-
Suri, C.; Jones, P. F.; Patan, S.; Bartunkova, S.; Maisonpierre, P. C.; Davis, S.; Sato, T. N.; Yancopoulos, G. D. Requisite role of angiopoietin-1, a ligand for the TIE2 Receptor, during embryonic angiogenesis. Cell 87:1171-1180; 1996.
-
(1996)
Cell
, vol.87
, pp. 1171-1180
-
-
Suri, C.1
Jones, P.F.2
Patan, S.3
Bartunkova, S.4
Maisonpierre, P.C.5
Davis, S.6
Sato, T.N.7
Yancopoulos, G.D.8
-
29
-
-
0032538385
-
Increased vascularization in mice overexpressing angiopoietin-1
-
Suri, C.; McClain, J.; Thurston, G.; McDonald, D. H.; Zhou, H.; Oldmixon, E. H.; Sato, T. N.; Yancopoulos, G. D. Increased vascularization in mice overexpressing angiopoietin-1. Science 282:468-471; 1998.
-
(1998)
Science
, vol.282
, pp. 468-471
-
-
Suri, C.1
McClain, J.2
Thurston, G.3
McDonald, D.H.4
Zhou, H.5
Oldmixon, E.H.6
Sato, T.N.7
Yancopoulos, G.D.8
-
30
-
-
0034036689
-
Angiopoietin-1 protects the adult vasculature against plasma leakage
-
Thurston, G.; Rudge, J. S.; Ioffe, E.; Zhou, H.; Ross, L.; Croll, S. D.; Glazer, N.; Holash, J.; McDonald, D. M.; Yancopoulos, G. D. Angiopoietin-1 protects the adult vasculature against plasma leakage. Nat. Med. 6:460-463; 2000.
-
(2000)
Nat. Med.
, vol.6
, pp. 460-463
-
-
Thurston, G.1
Rudge, J.S.2
Ioffe, E.3
Zhou, H.4
Ross, L.5
Croll, S.D.6
Glazer, N.7
Holash, J.8
McDonald, D.M.9
Yancopoulos, G.D.10
-
31
-
-
0033601357
-
Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1
-
Thurston, G.; Suri, C.; Smith, K.; McClain, J.; Sato, T. N.; Yancopoulos, G. D.; McDonald, D. M. Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1. Science 286:2511-2514; 1999.
-
(1999)
Science
, vol.286
, pp. 2511-2514
-
-
Thurston, G.1
Suri, C.2
Smith, K.3
McClain, J.4
Sato, T.N.5
Yancopoulos, G.D.6
McDonald, D.M.7
-
32
-
-
11244337801
-
Protective role of angiopoietin-1 in endotoxic shock
-
Witzenbichler, B.; Westermann, D.; Knueppel, S.; Schultheiss, H. P.; Tschope, C. Protective role of angiopoietin-1 in endotoxic shock. Circulation 111:97-105; 2005.
-
(2005)
Circulation
, vol.111
, pp. 97-105
-
-
Witzenbichler, B.1
Westermann, D.2
Knueppel, S.3
Schultheiss, H.P.4
Tschope, C.5
-
33
-
-
8344271026
-
Production of recombinant protein therapeutics in cultivated mammalian cells
-
Wurm, F. M. Production of recombinant protein therapeutics in cultivated mammalian cells. Nat. Biotechnol. 22:1393-1398; 2004.
-
(2004)
Nat. Biotechnol.
, vol.22
, pp. 1393-1398
-
-
Wurm, F.M.1
|