The crystal structure of a five-stranded coiled coil in COMP: A prototype ion channel?

Science

Volumn 274, Issue 5288, 1996, Pages 761-765

  Malashkevich, Vladimir N ^a   Kammerer, Richard A ^a   Efimov, Vladimir P ^a,b   Schulthess, Therese ^a   Engel, Jürgen ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINERGIC RECEPTOR; DISULFIDE; GLUTAMINE; ION CHANNEL; MATRIX PROTEIN; PHOSPHOLAMBAN; SCLEROPROTEIN; THROMBOSPONDIN;

ALPHA HELIX; ARTICLE; CRYSTAL STRUCTURE; EXTRACELLULAR MATRIX; HYDROPHOBICITY; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN STRUCTURE; THERMOSTABILITY;

AMINO ACID SEQUENCE; ANIMALS; CHLORIDE CHANNELS; CHLORIDES; CRYSTALLOGRAPHY, X-RAY; DISULFIDES; EXTRACELLULAR MATRIX PROTEINS; GLUTAMINE; GLYCOPROTEINS; HUMANS; HYDROGEN BONDING; ION CHANNELS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; SEQUENCE ALIGNMENT;

EID: 0029911261     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.274.5288.761     Document Type: Article

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37. Supported in part by Swiss National Science Foundation grant 31-32251.91 to J.E. We thank J. N. Jansonius for support and for providing access to x-ray equipment, and also for valuable comments on the manuscript. Coordinates have been deposited in the Brookhaven Protein Bank (entry code, 1VDF).