Cytotoxic activity of sanguinarine and dihydrosanguinarine in human promyelocytic leukemia HL-60 cells

Toxicology in Vitro

Volumn 23, Issue 4, 2009, Pages 580-588

  Vrba, Jiří ^a   Doležel, Petr ^a   Vičar, Jaroslav ^a   Ulrichová, Jitka ^a  

^a PALACKÝ UNIVERSITY   (Czech Republic)

Author keywords

Apoptosis; Cell cycle; Cytotoxicity; Dihydrosanguinarine; HL 60 cells; Mitochondrial membrane potential; Necrosis; Sanguinarine

Indexed keywords

ALKALOID; CASPASE 3; CASPASE 8; CASPASE 9; CELL DNA; DIHYDROSANGUINARINE; LIPOCORTIN 5; PROPIDIUM IODIDE; SANGUINARINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL ASSAY; CELL CYCLE; CELL DEATH; CELL MEMBRANE; CELL STRAIN HL 60; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INDUCTION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50; IMMUNOHISTOCHEMISTRY; MITOCHONDRIAL MEMBRANE POTENTIAL; PROMYELOCYTIC LEUKEMIA;

EID: 67349251852     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2009.01.016     Document Type: Article

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