-
1
-
-
0242573465
-
Katalyse: Vom Stein der Weisen zu Wilhelm Ostwald
-
Ertl G., and Gloyna T. Katalyse: Vom Stein der Weisen zu Wilhelm Ostwald. Z. Phys. Chem. 217 (2003) 1207-1219
-
(2003)
Z. Phys. Chem.
, vol.217
, pp. 1207-1219
-
-
Ertl, G.1
Gloyna, T.2
-
2
-
-
38949170701
-
Ueber die Bildung des Bittermandelöls
-
Wöhler F., and Liebig J. Ueber die Bildung des Bittermandelöls. Annalen der Pharmazie 22 (1837) 1-24
-
(1837)
Annalen der Pharmazie
, vol.22
, pp. 1-24
-
-
Wöhler, F.1
Liebig, J.2
-
4
-
-
67349184298
-
-
Nobel Lecture, available at
-
Ostwald W. (1909), On Catalysis, Nobel Lecture, available at http://nobelprize.org/nobel_prizes/chemistry/laureates/1909/ostwald-lect ure.html.
-
(1909)
On Catalysis
-
-
Ostwald, W.1
-
6
-
-
53549108051
-
Reactions at surfaces: from atoms to complexity
-
Ertl G. Reactions at surfaces: from atoms to complexity. Angew. Chem. Int. Ed. 47 (2008) 3524-3535
-
(2008)
Angew. Chem. Int. Ed.
, vol.47
, pp. 3524-3535
-
-
Ertl, G.1
-
8
-
-
36348937198
-
The E Factor: fifteen years on
-
Sheldon R. The E Factor: fifteen years on. Green Chem. 9 (2007) 1273-1283
-
(2007)
Green Chem.
, vol.9
, pp. 1273-1283
-
-
Sheldon, R.1
-
9
-
-
33947602410
-
Total synthesis of marine natural products without using protecting groups
-
Baran P.S., et al. Total synthesis of marine natural products without using protecting groups. Nature 446 (2007) 404-408
-
(2007)
Nature
, vol.446
, pp. 404-408
-
-
Baran, P.S.1
-
10
-
-
0032541073
-
The role of science in sustainable development
-
Merkel A. The role of science in sustainable development. Science 281 (1998) 336-337
-
(1998)
Science
, vol.281
, pp. 336-337
-
-
Merkel, A.1
-
11
-
-
44449089547
-
Opportunities for renewable bioenergy using micro-organisms
-
Rittmann B.E. Opportunities for renewable bioenergy using micro-organisms. Biotech. Bioeng. 100 (2008) 203-212
-
(2008)
Biotech. Bioeng.
, vol.100
, pp. 203-212
-
-
Rittmann, B.E.1
-
12
-
-
33846950348
-
Challenges in engineering microbes for biofuels production
-
Stephanopoulos G. Challenges in engineering microbes for biofuels production. Science 315 (2007) 801-804
-
(2007)
Science
, vol.315
, pp. 801-804
-
-
Stephanopoulos, G.1
-
13
-
-
43049084715
-
Biomass to fuels via microbial transformations
-
Wackett L.P. Biomass to fuels via microbial transformations. Curr. Opin. Chem. Biol. 12 (2008) 187-193
-
(2008)
Curr. Opin. Chem. Biol.
, vol.12
, pp. 187-193
-
-
Wackett, L.P.1
-
14
-
-
49649106060
-
The Genomics of cellulosic biofuels
-
Rubin E.M. The Genomics of cellulosic biofuels. Nature 454 (2008) 841-845
-
(2008)
Nature
, vol.454
, pp. 841-845
-
-
Rubin, E.M.1
-
15
-
-
45049086849
-
Biofuel alternatives to ethanol: pumping the micro bial well
-
Fortman J.L., et al. Biofuel alternatives to ethanol: pumping the micro bial well. Trends Biotechnol. 26 (2008) 375-381
-
(2008)
Trends Biotechnol.
, vol.26
, pp. 375-381
-
-
Fortman, J.L.1
-
16
-
-
31544452808
-
The path forward for biofuels and biomaterials
-
Ragauskas A.J., et al. The path forward for biofuels and biomaterials. Science 311 (2006) 484-489
-
(2006)
Science
, vol.311
, pp. 484-489
-
-
Ragauskas, A.J.1
-
17
-
-
48149113309
-
The renewable chemicals industry
-
Christensen C.H., et al. The renewable chemicals industry. Chem. Sus. Chem. 1 (2008) 283-289
-
(2008)
Chem. Sus. Chem.
, vol.1
, pp. 283-289
-
-
Christensen, C.H.1
-
18
-
-
36248991352
-
Producing bio-based bulk chemicals using industrial biotechnology
-
Hermann B.G., et al. Producing bio-based bulk chemicals using industrial biotechnology. Environ. Sci. Technol. 41 (2007) 7915-7921
-
(2007)
Environ. Sci. Technol.
, vol.41
, pp. 7915-7921
-
-
Hermann, B.G.1
-
19
-
-
67349275989
-
-
Barton, D. and Nakanishi, K., (eds-in-chief) (1999) Comprehensive Natural Products Chemistry, 1-9, Elsevier
-
Barton, D. and Nakanishi, K., (eds-in-chief) (1999) Comprehensive Natural Products Chemistry, vol. 1-9, Elsevier
-
-
-
-
20
-
-
0004143149
-
-
Steinbüchel, A, ed, Wiley-VCH
-
Steinbüchel, A., (ed.) (2001) Biopolymers, vol. 1-10, Wiley-VCH
-
(2001)
Biopolymers
, vol.1-10
-
-
-
21
-
-
0000096302
-
10 years after rio-concepts on the contribution of chemistry to a sustainable development
-
Eissen M., et al. 10 years after rio-concepts on the contribution of chemistry to a sustainable development. Angew. Chem. Int. Ed. 114 (2002) 402-425
-
(2002)
Angew. Chem. Int. Ed.
, vol.114
, pp. 402-425
-
-
Eissen, M.1
-
22
-
-
33847030736
-
Industrial biotechnology for the production of bio-based chemicals-a cradle-to-grave perspective
-
Hatti-Kaul R., et al. Industrial biotechnology for the production of bio-based chemicals-a cradle-to-grave perspective. Trends Biotechnol. 25 (2007) 119-124
-
(2007)
Trends Biotechnol.
, vol.25
, pp. 119-124
-
-
Hatti-Kaul, R.1
-
23
-
-
38349093902
-
Microbial production of organic acids: expanding the markets
-
Sauer M., et al. Microbial production of organic acids: expanding the markets. Trends Biotechnol. 26 (2008) 100-108
-
(2008)
Trends Biotechnol.
, vol.26
, pp. 100-108
-
-
Sauer, M.1
-
24
-
-
34250835050
-
Production of dimethylfuran for liquid fuels from biomass-derived carbohydrates
-
Roman-Leshkov Y., et al. Production of dimethylfuran for liquid fuels from biomass-derived carbohydrates. Nature 447 (2007) 982-985
-
(2007)
Nature
, vol.447
, pp. 982-985
-
-
Roman-Leshkov, Y.1
-
25
-
-
0030618171
-
The value of the world's ecosystem services and natural capital
-
Costanza R., et al. The value of the world's ecosystem services and natural capital. Nature 387 (1997) 253-260
-
(1997)
Nature
, vol.387
, pp. 253-260
-
-
Costanza, R.1
-
26
-
-
34247109045
-
Natural products as sources of new drugs over the last 25 years
-
Newman D.J., and Cragg G.M. Natural products as sources of new drugs over the last 25 years. J. Nat. Prod. 70 (2007) 461-477
-
(2007)
J. Nat. Prod.
, vol.70
, pp. 461-477
-
-
Newman, D.J.1
Cragg, G.M.2
-
30
-
-
0037436563
-
Dispelling the myths-biocatalysis in industrial synthesis
-
Schoemaker H.E., et al. Dispelling the myths-biocatalysis in industrial synthesis. Science 299 (2003) 1694-1698
-
(2003)
Science
, vol.299
, pp. 1694-1698
-
-
Schoemaker, H.E.1
-
31
-
-
0242438894
-
Lonza: 20 Years of biotransformations
-
Shaw N., et al. Lonza: 20 Years of biotransformations. Adv. Synth. Catal. 345 (2003) 425-435
-
(2003)
Adv. Synth. Catal.
, vol.345
, pp. 425-435
-
-
Shaw, N.1
-
32
-
-
1842578074
-
Industrial methods for the production of optically active intermediates
-
Breuer M., et al. Industrial methods for the production of optically active intermediates. Angew. Chem. Int. Ed. 43 (2004) 788-824
-
(2004)
Angew. Chem. Int. Ed.
, vol.43
, pp. 788-824
-
-
Breuer, M.1
-
34
-
-
0003479152
-
-
Springer Verlag
-
th edn (2004), Springer Verlag
-
(2004)
th edn
-
-
Faber, K.1
-
36
-
-
0037212099
-
Accelerated design of bioconversion processes using automated microscale processing techniques
-
Lye G.J., et al. Accelerated design of bioconversion processes using automated microscale processing techniques. Trends Biotechnol. 21 (2003) 29-37
-
(2003)
Trends Biotechnol.
, vol.21
, pp. 29-37
-
-
Lye, G.J.1
-
37
-
-
47249096975
-
Application of systems biology for bioprocess development
-
Park J.H., et al. Application of systems biology for bioprocess development. Trends Biotechnol. 26 (2008) 404-412
-
(2008)
Trends Biotechnol.
, vol.26
, pp. 404-412
-
-
Park, J.H.1
-
38
-
-
77952472624
-
Modular and scalable biocatalytic tools for practical safety, health and environmental improvements in the production of speciality chemicals
-
Wohlgemuth R. Modular and scalable biocatalytic tools for practical safety, health and environmental improvements in the production of speciality chemicals. Biocat. Biotrans. 25 (2007) 178-185
-
(2007)
Biocat. Biotrans.
, vol.25
, pp. 178-185
-
-
Wohlgemuth, R.1
-
39
-
-
38449104428
-
Strain improvement for production of pharmaceuticals and other microbial metabolites by fermentation
-
Demain A.L., and Adrio J.L. Strain improvement for production of pharmaceuticals and other microbial metabolites by fermentation. Prog. Drug Res. 65 (2008) 25-289
-
(2008)
Prog. Drug Res.
, vol.65
, pp. 25-289
-
-
Demain, A.L.1
Adrio, J.L.2
-
40
-
-
0038119760
-
Auxiliary phase guidelines for microbial bio-transformations of toxic substrate into toxic product
-
Straathof A.J.J. Auxiliary phase guidelines for microbial bio-transformations of toxic substrate into toxic product. Biotechnol. Prog. 19 (2003) 755-762
-
(2003)
Biotechnol. Prog.
, vol.19
, pp. 755-762
-
-
Straathof, A.J.J.1
-
41
-
-
34547209337
-
Enzyme immobilization: the quest for optimum performance
-
Sheldon R.A. Enzyme immobilization: the quest for optimum performance. Adv. Synth. Catal. 349 (2007) 1289-1307
-
(2007)
Adv. Synth. Catal.
, vol.349
, pp. 1289-1307
-
-
Sheldon, R.A.1
-
42
-
-
33947585795
-
The production of (R)-2-hydroxy-1-phenyl-propan-1-one derivatives by benzaldehyde lyase from Pseudomonas fluorescens in a continuously operated membrane reactor
-
Hildebrand F., et al. The production of (R)-2-hydroxy-1-phenyl-propan-1-one derivatives by benzaldehyde lyase from Pseudomonas fluorescens in a continuously operated membrane reactor. Biotech. Bioeng. 96 (2007) 835-843
-
(2007)
Biotech. Bioeng.
, vol.96
, pp. 835-843
-
-
Hildebrand, F.1
-
43
-
-
0037948335
-
In situ product removal (ISPR) in whole cell biotechnology during the last twenty years
-
Stark D., and von Stockar U. In situ product removal (ISPR) in whole cell biotechnology during the last twenty years. Adv. Biochem. Eng. Biotechnol. 80 (2003) 149-175
-
(2003)
Adv. Biochem. Eng. Biotechnol.
, vol.80
, pp. 149-175
-
-
Stark, D.1
von Stockar, U.2
-
44
-
-
0343580463
-
The effect of absorbing resins on substrate concentration and enantiomeric excess in yeast reduction
-
D'Arrigo P., et al. The effect of absorbing resins on substrate concentration and enantiomeric excess in yeast reduction. Tetrahedron: Asymmetr. 8 (1997) 2375-2379
-
(1997)
Tetrahedron: Asymmetr.
, vol.8
, pp. 2375-2379
-
-
D'Arrigo, P.1
-
45
-
-
2942586917
-
In situ product removal using a crystallization loop in asymmetric reduction of 4-oxoisophorone by Saccharomyces cerevisiae
-
Buque-Taboada E.M., et al. In situ product removal using a crystallization loop in asymmetric reduction of 4-oxoisophorone by Saccharomyces cerevisiae. Biotech. Bioeng. 86 (2004) 795-800
-
(2004)
Biotech. Bioeng.
, vol.86
, pp. 795-800
-
-
Buque-Taboada, E.M.1
-
46
-
-
0023385987
-
Rules for optimization of biocatalysis in organic solvents
-
Laane C., et al. Rules for optimization of biocatalysis in organic solvents. Biotech. Bioeng. 30 (1987) 81-87
-
(1987)
Biotech. Bioeng.
, vol.30
, pp. 81-87
-
-
Laane, C.1
-
47
-
-
0042808596
-
Is log P a convenient criterion to guide the choice of solvents for biphasic enzymatic reactions?
-
Villela Filho M., et al. Is log P a convenient criterion to guide the choice of solvents for biphasic enzymatic reactions?. Angew. Chem. Int. Ed. 42 (2003) 116-124
-
(2003)
Angew. Chem. Int. Ed.
, vol.42
, pp. 116-124
-
-
Villela Filho, M.1
-
48
-
-
41449115770
-
Prediction of partition coefficients using COSMO-RS: solvent screening for maximum conversion in biocatalytic two-phase reaction systems
-
Spiess A.C., et al. Prediction of partition coefficients using COSMO-RS: solvent screening for maximum conversion in biocatalytic two-phase reaction systems. Chem. Eng. Proc. 47 (2008) 1034-1041
-
(2008)
Chem. Eng. Proc.
, vol.47
, pp. 1034-1041
-
-
Spiess, A.C.1
-
49
-
-
0003399463
-
-
Mattiasson B., and Holst O. (Eds), Marcel Dekker Inc.
-
In: Mattiasson B., and Holst O. (Eds). Extractive Bioconversions (1991), Marcel Dekker Inc.
-
(1991)
Extractive Bioconversions
-
-
-
50
-
-
0032481065
-
Extractive biocatalysis: a powerful tool in selectivity control in yeast biotransformations
-
D'Arrigo P., et al. Extractive biocatalysis: a powerful tool in selectivity control in yeast biotransformations. Tetrahedron 54 (1998) 15017-15026
-
(1998)
Tetrahedron
, vol.54
, pp. 15017-15026
-
-
D'Arrigo, P.1
-
52
-
-
37349126715
-
Enzyme activation for organic solvents made easy
-
Serdakowsky A.L., and Dordick J.S. Enzyme activation for organic solvents made easy. Trends Biotechnol. 26 (2007) 48-54
-
(2007)
Trends Biotechnol.
, vol.26
, pp. 48-54
-
-
Serdakowsky, A.L.1
Dordick, J.S.2
-
54
-
-
0037712741
-
Membrane-assisted extractive bioconversions
-
Fernandes P., et al. Membrane-assisted extractive bioconversions. Adv. Biochem. Eng. Biotechnol. 80 (2003) 115-148
-
(2003)
Adv. Biochem. Eng. Biotechnol.
, vol.80
, pp. 115-148
-
-
Fernandes, P.1
-
55
-
-
1942471051
-
Microbial Transformations, 56. Preparative scale asymmetric Baeyer-Villiger oxidation using a highly productive two-in-one resin-based in situ SFPR concept
-
Hilker I., et al. Microbial Transformations, 56. Preparative scale asymmetric Baeyer-Villiger oxidation using a highly productive two-in-one resin-based in situ SFPR concept. Adv. Synth. Catal. 346 (2003) 203-214
-
(2003)
Adv. Synth. Catal.
, vol.346
, pp. 203-214
-
-
Hilker, I.1
-
56
-
-
3042839971
-
Microbiological transformations 57. Facile and efficient resin-based in situ SFPR preparative scale synthesis of an enantiopure 'unexpected' lactone regioisomer via a Baeyer-Villiger oxidation process
-
Hilker I., et al. Microbiological transformations 57. Facile and efficient resin-based in situ SFPR preparative scale synthesis of an enantiopure 'unexpected' lactone regioisomer via a Baeyer-Villiger oxidation process. Org. Lett. 6 (2004) 1955-1958
-
(2004)
Org. Lett.
, vol.6
, pp. 1955-1958
-
-
Hilker, I.1
-
57
-
-
28844495429
-
Microbial transformations 59. First kilogram scale asymmetric microbial Baeyer-Villiger oxidation with optimised productivity using a resin based in situ SFPR strategy
-
Hilker I., et al. Microbial transformations 59. First kilogram scale asymmetric microbial Baeyer-Villiger oxidation with optimised productivity using a resin based in situ SFPR strategy. Biotech. Bioeng. 92 (2005) 704-710
-
(2005)
Biotech. Bioeng.
, vol.92
, pp. 704-710
-
-
Hilker, I.1
-
58
-
-
33646022877
-
On the influence of oxygen and cell concentration in an SFPR whole cell biocatalytic Baeyer-Villiger oxidation process
-
Hilker I., et al. On the influence of oxygen and cell concentration in an SFPR whole cell biocatalytic Baeyer-Villiger oxidation process. Biotechnol. Bioeng. 93 (2006) 1138-1144
-
(2006)
Biotechnol. Bioeng.
, vol.93
, pp. 1138-1144
-
-
Hilker, I.1
-
59
-
-
20844433475
-
Multi-step organic synthesis using solid-supported reagents and scavengers: a new paradigm in chemical library generation.
-
Ley S.V., et al. Multi-step organic synthesis using solid-supported reagents and scavengers: a new paradigm in chemical library generation. J. Chem. Soc., Perk. Transac. I (2000) 3815-4195
-
(2000)
J. Chem. Soc., Perk. Transac. I
, pp. 3815-4195
-
-
Ley, S.V.1
-
60
-
-
0037419178
-
12: a 35-year odyssey
-
12: a 35-year odyssey. J. Org. Chem. 68 (2003) 2529-2539
-
(2003)
J. Org. Chem.
, vol.68
, pp. 2529-2539
-
-
Scott, A.I.1
-
61
-
-
0029167396
-
12: how the problem of its biosynthesis was solved
-
12: how the problem of its biosynthesis was solved. Angew. Chem. Int. Ed. Engl. 34 (1995) 383-411
-
(1995)
Angew. Chem. Int. Ed. Engl.
, vol.34
, pp. 383-411
-
-
Blanche, F.1
-
62
-
-
0023846718
-
12: experiments concerning the origin of its molecular structure
-
12: experiments concerning the origin of its molecular structure. Angew. Chem. Int. Ed. Engl. 27 (1988) 5-39
-
(1988)
Angew. Chem. Int. Ed. Engl.
, vol.27
, pp. 5-39
-
-
Eschenmoser, A.1
-
63
-
-
47249096975
-
Application of systems biology for bioprocess development
-
Park J.H., et al. Application of systems biology for bioprocess development. Trends Biotechnol. 26 (2008) 404-411
-
(2008)
Trends Biotechnol.
, vol.26
, pp. 404-411
-
-
Park, J.H.1
-
65
-
-
33846927258
-
Scale-down and parallel operation of the riboflavin production process with Bacillus subtilis
-
Knorr B., et al. Scale-down and parallel operation of the riboflavin production process with Bacillus subtilis. Biochem. Eng. J. 33 (2007) 263-274
-
(2007)
Biochem. Eng. J.
, vol.33
, pp. 263-274
-
-
Knorr, B.1
-
66
-
-
34248347072
-
Microbioreactors for bioprocess development
-
Zhang Z., et al. Microbioreactors for bioprocess development. J. Assoc. Lab. Automat. 12 (2007) 143-151
-
(2007)
J. Assoc. Lab. Automat.
, vol.12
, pp. 143-151
-
-
Zhang, Z.1
-
67
-
-
84982339804
-
Eine ergiebige synthese der l-ascorbinsäure (vitamin C)
-
Reichstein T., and Grüssner A. Eine ergiebige synthese der l-ascorbinsäure (vitamin C). Helv. Chim. Acta 17 (1934) 311-328
-
(1934)
Helv. Chim. Acta
, vol.17
, pp. 311-328
-
-
Reichstein, T.1
Grüssner, A.2
-
68
-
-
0023875288
-
Microbial and enzymatic processes for the production of biologically and chemically useful compounds
-
Yamada H., and Shimizu S. Microbial and enzymatic processes for the production of biologically and chemically useful compounds. Angew. Chem. Int. Ed. 27 (1988) 622-642
-
(1988)
Angew. Chem. Int. Ed.
, vol.27
, pp. 622-642
-
-
Yamada, H.1
Shimizu, S.2
-
69
-
-
33745764380
-
Chemocatalysis and (Biotransforma-tion): some thoughts of a chemist and of a biotechnologist
-
Leresche J.E., and Meyer H.P. Chemocatalysis and (Biotransforma-tion): some thoughts of a chemist and of a biotechnologist. Org. Proc. Res. Dev. 10 (2006) 572-580
-
(2006)
Org. Proc. Res. Dev.
, vol.10
, pp. 572-580
-
-
Leresche, J.E.1
Meyer, H.P.2
-
70
-
-
46849084792
-
New, efficient synthesis of oseltamivir phosphate (Tamiflu) via enzymatic desymmetrization of a meso-1,3-cyclohexane-dicarboxylic acid diester
-
Zutter U., et al. New, efficient synthesis of oseltamivir phosphate (Tamiflu) via enzymatic desymmetrization of a meso-1,3-cyclohexane-dicarboxylic acid diester. J. Org. Chem. 73 (2008) 4895-4902
-
(2008)
J. Org. Chem.
, vol.73
, pp. 4895-4902
-
-
Zutter, U.1
-
71
-
-
36349020871
-
Interfacing biocatalysis and organic synthesis
-
Wohlgemuth R. Interfacing biocatalysis and organic synthesis. J. Chem. Technol. Biotechnol. 82 (2007) 1055-1062
-
(2007)
J. Chem. Technol. Biotechnol.
, vol.82
, pp. 1055-1062
-
-
Wohlgemuth, R.1
-
72
-
-
34247279272
-
Recent advances in developing chemoenzymatic processes for active pharmaceutical ingredients
-
Tao J., et al. Recent advances in developing chemoenzymatic processes for active pharmaceutical ingredients. Org. Proc. Res. Dev. 11 (2007) 259-267
-
(2007)
Org. Proc. Res. Dev.
, vol.11
, pp. 259-267
-
-
Tao, J.1
-
73
-
-
0001601505
-
Retrosynthetic thinking-essentials and examples
-
Corey E.J. Retrosynthetic thinking-essentials and examples. Chem. Soc. Rev. 17 (1988) 111-133
-
(1988)
Chem. Soc. Rev.
, vol.17
, pp. 111-133
-
-
Corey, E.J.1
-
74
-
-
43649098961
-
New opportunities for biocatalysis: making pharmaceutical processes greener
-
Woodley J.M. New opportunities for biocatalysis: making pharmaceutical processes greener. Trends Biotechnol. 26 (2008) 321-327
-
(2008)
Trends Biotechnol.
, vol.26
, pp. 321-327
-
-
Woodley, J.M.1
-
75
-
-
33846781724
-
Future aspects of bioprocess monitoring
-
Becker T., et al. Future aspects of bioprocess monitoring. Adv. Biochem. Eng. Biotechnol. 105 (2007) 249-293
-
(2007)
Adv. Biochem. Eng. Biotechnol.
, vol.105
, pp. 249-293
-
-
Becker, T.1
-
76
-
-
41449086291
-
Bioprocess Analysis
-
Rehbock C., et al. Bioprocess Analysis. Chemie Ingenieur Technik 80 (2008) 267-286
-
(2008)
Chemie Ingenieur Technik
, vol.80
, pp. 267-286
-
-
Rehbock, C.1
-
77
-
-
33748928503
-
FDA update: process analytical technology for biotechnology products
-
Webber K. FDA update: process analytical technology for biotechnology products. PAT-J. Proc. Anal. Technol. 2 (2005) 12-14
-
(2005)
PAT-J. Proc. Anal. Technol.
, vol.2
, pp. 12-14
-
-
Webber, K.1
-
78
-
-
33747175248
-
Process analytical technology in biopharmaceutical production: past successes and future challenges
-
Larson T.M., and Lam H. Process analytical technology in biopharmaceutical production: past successes and future challenges. PAT-J. Proc. Anal. Technol. 1 (2004) 20-22
-
(2004)
PAT-J. Proc. Anal. Technol.
, vol.1
, pp. 20-22
-
-
Larson, T.M.1
Lam, H.2
-
79
-
-
33846783254
-
Enabling technologies: fermentation and down-stream processing
-
Weuster-Botz D., et al. Enabling technologies: fermentation and down-stream processing. Adv. Biochem. Eng. Biotechnol. 105 (2007) 205-247
-
(2007)
Adv. Biochem. Eng. Biotechnol.
, vol.105
, pp. 205-247
-
-
Weuster-Botz, D.1
-
80
-
-
44049087166
-
Multiplex bacterial growth monitoring in 24-Well microplates using a dual optical sensor for dissolved oxygen and pH
-
Kocincova, et al. Multiplex bacterial growth monitoring in 24-Well microplates using a dual optical sensor for dissolved oxygen and pH. Biotech. Bioeng. 100 (2008) 430-438
-
(2008)
Biotech. Bioeng.
, vol.100
, pp. 430-438
-
-
Kocincova1
-
81
-
-
44449122383
-
Case study and applications of process analytical technology (PAT) towards bioprocessing: use of on-line high-performance liquid chromatography (HPLC) for making real-time pooling decisions for process chromatography
-
Rathore A., et al. Case study and applications of process analytical technology (PAT) towards bioprocessing: use of on-line high-performance liquid chromatography (HPLC) for making real-time pooling decisions for process chromatography. Bioetch. Bioeng. 100 (2008) 306-316
-
(2008)
Bioetch. Bioeng.
, vol.100
, pp. 306-316
-
-
Rathore, A.1
-
82
-
-
34347207960
-
Process analytical chemistry
-
Workman J., et al. Process analytical chemistry. Anal. Chem. 79 (2007) 4345-4364
-
(2007)
Anal. Chem.
, vol.79
, pp. 4345-4364
-
-
Workman, J.1
-
83
-
-
37249063120
-
Mass spectrometry analysis of new chemical entities for pharmaceutical discovery
-
Fang A.S., et al. Mass spectrometry analysis of new chemical entities for pharmaceutical discovery. Mass Spectrom. Rev. 27 (2008) 20-34
-
(2008)
Mass Spectrom. Rev.
, vol.27
, pp. 20-34
-
-
Fang, A.S.1
-
84
-
-
41049083709
-
Process analysis of macrotetrolide biosynthesis during fermentation by means of direct infusion LC-MS
-
Jani P., et al. Process analysis of macrotetrolide biosynthesis during fermentation by means of direct infusion LC-MS. Biotechnol. J. 3 (2008) 1-7
-
(2008)
Biotechnol. J.
, vol.3
, pp. 1-7
-
-
Jani, P.1
-
85
-
-
5644249240
-
Mass spectrometry sampling under ambient conditions with desorption electrospray ionization
-
Takats Z., et al. Mass spectrometry sampling under ambient conditions with desorption electrospray ionization. Science 306 (2004) 471-473
-
(2004)
Science
, vol.306
, pp. 471-473
-
-
Takats, Z.1
-
86
-
-
17644408113
-
Versatile new ion source for the analysis of materials in open air under ambient conditions
-
Cody R.B., et al. Versatile new ion source for the analysis of materials in open air under ambient conditions. Anal. Chem. 77 (2005) 2297-2302
-
(2005)
Anal. Chem.
, vol.77
, pp. 2297-2302
-
-
Cody, R.B.1
-
87
-
-
41049096359
-
Quantitative metabolomics using NMR
-
Wishart D.S. Quantitative metabolomics using NMR. Trends Anal. Chem. 27 (2008) 228-237
-
(2008)
Trends Anal. Chem.
, vol.27
, pp. 228-237
-
-
Wishart, D.S.1
-
89
-
-
45149131892
-
Advances in primary recovery: centrifugation and membrane technology
-
Roush D.J., and Lu Y. Advances in primary recovery: centrifugation and membrane technology. Biotechnol. Prog. 24 (2008) 488-495
-
(2008)
Biotechnol. Prog.
, vol.24
, pp. 488-495
-
-
Roush, D.J.1
Lu, Y.2
-
90
-
-
33645387937
-
An automated microscale technique for the quantitative and parallel analysis of microfiltration operations
-
Jackson N.B., et al. An automated microscale technique for the quantitative and parallel analysis of microfiltration operations. J. Membr. Sci. 276 (2006) 31-41
-
(2006)
J. Membr. Sci.
, vol.276
, pp. 31-41
-
-
Jackson, N.B.1
-
91
-
-
33745748886
-
Strategy for selection of methods for separation of bioparticles from particle mixtures
-
van Hee P., et al. Strategy for selection of methods for separation of bioparticles from particle mixtures. Biotech. Bioeng. 94 (2006) 689-709
-
(2006)
Biotech. Bioeng.
, vol.94
, pp. 689-709
-
-
van Hee, P.1
-
92
-
-
48449088099
-
Impact of clarification strategy on chromatographic separations: preprocessing of cell homogenates
-
Bracewell D.G., et al. Impact of clarification strategy on chromatographic separations: preprocessing of cell homogenates. Biotech. Bioeng. 100 (2008) 941-949
-
(2008)
Biotech. Bioeng.
, vol.100
, pp. 941-949
-
-
Bracewell, D.G.1
-
93
-
-
58149170278
-
Microscale HPLC predicts preparative performance at millionfold scale
-
Welch C.J., et al. Microscale HPLC predicts preparative performance at millionfold scale. Org. Proc. Res. Dev. 12 (2008) 674-677
-
(2008)
Org. Proc. Res. Dev.
, vol.12
, pp. 674-677
-
-
Welch, C.J.1
-
94
-
-
46249100489
-
High-throughput screening of chromatographic separations: IV. Ion-exchange
-
Kelley B.D., et al. High-throughput screening of chromatographic separations: IV. Ion-exchange. Biotech. Bioeng. 100 (2008) 950-963
-
(2008)
Biotech. Bioeng.
, vol.100
, pp. 950-963
-
-
Kelley, B.D.1
-
95
-
-
33744522283
-
Integrated operation of continuous chromatography and biotransformations for the generic high-yield production of fine chemicals
-
Bechtold M., et al. Integrated operation of continuous chromatography and biotransformations for the generic high-yield production of fine chemicals. J. Biotechnol. 124 (2006) 146-162
-
(2006)
J. Biotechnol.
, vol.124
, pp. 146-162
-
-
Bechtold, M.1
-
96
-
-
38849173149
-
Integrated process for production of surfactin Part 2. Equilibrium and kinetic study of surfactin adsorption onto activated carbon
-
Montastruc L., et al. Integrated process for production of surfactin Part 2. Equilibrium and kinetic study of surfactin adsorption onto activated carbon. Biochem. Eng. J. 38 (2007) 349-354
-
(2007)
Biochem. Eng. J.
, vol.38
, pp. 349-354
-
-
Montastruc, L.1
-
97
-
-
0030057479
-
Process integration aspects for the production of fine chemicals illustrated with the biotransformation of γ-butyrobetaine into l-carnitine
-
Hoeks F.W.J.M.M., et al. Process integration aspects for the production of fine chemicals illustrated with the biotransformation of γ-butyrobetaine into l-carnitine. Chem. Eng. J. 61 (1996) 53-61
-
(1996)
Chem. Eng. J.
, vol.61
, pp. 53-61
-
-
Hoeks, F.W.J.M.M.1
-
98
-
-
0026530668
-
Continuous cell-recycle process for l-carnitine production: performance, engineering and downstream processing aspects compared with discontinuous processes
-
Hoeks F.W.J.M.M., et al. Continuous cell-recycle process for l-carnitine production: performance, engineering and downstream processing aspects compared with discontinuous processes. J. Biotechnol. 22 (1992) 117-127
-
(1992)
J. Biotechnol.
, vol.22
, pp. 117-127
-
-
Hoeks, F.W.J.M.M.1
-
99
-
-
36349013777
-
Amino acid oxidase-catalysed resolution and Pictet-Spengler reaction towards chiral and rigid unnatural amino acids
-
Benz P., et al. Amino acid oxidase-catalysed resolution and Pictet-Spengler reaction towards chiral and rigid unnatural amino acids. J. Chem. Technol. Biotechnol. 82 (2007) 1082-1087
-
(2007)
J. Chem. Technol. Biotechnol.
, vol.82
, pp. 1082-1087
-
-
Benz, P.1
-
100
-
-
58149159360
-
Development of a chemoenzymatic manufacturing process for pregabalin
-
Martinez C.A., et al. Development of a chemoenzymatic manufacturing process for pregabalin. Org. Proc. Res. Dev. 12 (2008) 392-398
-
(2008)
Org. Proc. Res. Dev.
, vol.12
, pp. 392-398
-
-
Martinez, C.A.1
-
101
-
-
53549086464
-
The first 200-L scale asymmetric Baeyer-Villiger oxidation using a whole-cell biocatalyst
-
Baldwin C.V.F., et al. The first 200-L scale asymmetric Baeyer-Villiger oxidation using a whole-cell biocatalyst. Org. Proc. Res. Dev. 12 (2008) 660-665
-
(2008)
Org. Proc. Res. Dev.
, vol.12
, pp. 660-665
-
-
Baldwin, C.V.F.1
-
102
-
-
34447307120
-
Combination of biotransformation and chromatography for the isolation and purification of mannoheptulose
-
Kappler-Tanudyaya N., et al. Combination of biotransformation and chromatography for the isolation and purification of mannoheptulose. Biotechnol. J. 2 (2007) 692-699
-
(2007)
Biotechnol. J.
, vol.2
, pp. 692-699
-
-
Kappler-Tanudyaya, N.1
-
103
-
-
38849197846
-
Future directions for in situ product removal (ISPR)
-
Woodley J.M., et al. Future directions for in situ product removal (ISPR). J. Chem. Technol. Biotechnol. 83 (2008) 121-123
-
(2008)
J. Chem. Technol. Biotechnol.
, vol.83
, pp. 121-123
-
-
Woodley, J.M.1
-
104
-
-
84995597909
-
Two-Phase (bio) catalytic reactions in a table-top centrifugal contact separator
-
Kraai G.N., et al. Two-Phase (bio) catalytic reactions in a table-top centrifugal contact separator. Angew. Chem. Int. Ed. 120 (2008) 3969-3972
-
(2008)
Angew. Chem. Int. Ed.
, vol.120
, pp. 3969-3972
-
-
Kraai, G.N.1
-
105
-
-
44049107264
-
Solvent-impregnated resins as in situ product recovery tools for phenol recovery from Pseudomonas putida S12TPL fermentations
-
van den Berg C., et al. Solvent-impregnated resins as in situ product recovery tools for phenol recovery from Pseudomonas putida S12TPL fermentations. Biotech. Bioeng. 100 (2008) 466-472
-
(2008)
Biotech. Bioeng.
, vol.100
, pp. 466-472
-
-
van den Berg, C.1
-
106
-
-
23244456246
-
Enhanced production of surfactin from Bacillus subtilis by addition of solid carriers
-
Yeh M.S., et al. Enhanced production of surfactin from Bacillus subtilis by addition of solid carriers. Biotechnol. Prog. 21 (2005) 1329-1334
-
(2005)
Biotechnol. Prog.
, vol.21
, pp. 1329-1334
-
-
Yeh, M.S.1
-
107
-
-
0037075689
-
Overview of screening for new microbial catalysts and their uses in organic synthesis-selection and optimization of biocatalysts
-
Asano Y. Overview of screening for new microbial catalysts and their uses in organic synthesis-selection and optimization of biocatalysts. J. Biotechnol. 94 (2002) 65-72
-
(2002)
J. Biotechnol.
, vol.94
, pp. 65-72
-
-
Asano, Y.1
-
108
-
-
0036669691
-
Industrial microbial enzymes: their discovery by screening and use in large-scale production of usefulchemicals in Japan
-
Ogawa J., and Shimizu S. Industrial microbial enzymes: their discovery by screening and use in large-scale production of usefulchemicals in Japan. Curr. Opin. Biotechnol. 13 (2002) 1-9
-
(2002)
Curr. Opin. Biotechnol.
, vol.13
, pp. 1-9
-
-
Ogawa, J.1
Shimizu, S.2
-
109
-
-
36749063615
-
The micro-Petri dish, a million-well growth chip for the culture and high-throughput screening of microorganisms
-
Ingham C.J., et al. The micro-Petri dish, a million-well growth chip for the culture and high-throughput screening of microorganisms. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 18217-18222
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 18217-18222
-
-
Ingham, C.J.1
-
110
-
-
0037131390
-
Microfluidic large-scale integration
-
Thorsen T., et al. Microfluidic large-scale integration. Science 298 (2002) 580-584
-
(2002)
Science
, vol.298
, pp. 580-584
-
-
Thorsen, T.1
-
112
-
-
33748595526
-
Mechanism-based profiling of enzyme families
-
Evans M.J., and Cravatt B.F. Mechanism-based profiling of enzyme families. Chem. Rev. 106 (2006) 3279-3301
-
(2006)
Chem. Rev.
, vol.106
, pp. 3279-3301
-
-
Evans, M.J.1
Cravatt, B.F.2
-
114
-
-
1942503297
-
Controlling the enantioselectivity of enzymes by directed evolution: practical and theoretical ramifications
-
Reetz M.T. Controlling the enantioselectivity of enzymes by directed evolution: practical and theoretical ramifications. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 5716-5722
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 5716-5722
-
-
Reetz, M.T.1
-
115
-
-
0035313593
-
Improved biocatalysts by directed evolution and rational protein design
-
Bornscheuer U.T., and Pohl M. Improved biocatalysts by directed evolution and rational protein design. Curr. Opin. Chem. Biol. 5 (2001) 137-143
-
(2001)
Curr. Opin. Chem. Biol.
, vol.5
, pp. 137-143
-
-
Bornscheuer, U.T.1
Pohl, M.2
-
116
-
-
36849048228
-
Intrinsic motions along an enzymatic reaction trajectory
-
Henzler-Wildman K.A., et al. Intrinsic motions along an enzymatic reaction trajectory. Nature 450 (2007) 838-844
-
(2007)
Nature
, vol.450
, pp. 838-844
-
-
Henzler-Wildman, K.A.1
-
117
-
-
43449098518
-
Kemp elimination catalysts by computational enzyme design
-
Röthlisberger D., et al. Kemp elimination catalysts by computational enzyme design. Nature 453 (2008) 190-194
-
(2008)
Nature
, vol.453
, pp. 190-194
-
-
Röthlisberger, D.1
-
118
-
-
50549096107
-
Enhancing activity and controlling stereoselectivity in a designed PLP-dependent aldolase
-
Toscano M.D., et al. Enhancing activity and controlling stereoselectivity in a designed PLP-dependent aldolase. Angew. Chem. 119 (2007) 4552-4554
-
(2007)
Angew. Chem.
, vol.119
, pp. 4552-4554
-
-
Toscano, M.D.1
-
119
-
-
34547958191
-
Selection and evolution of enzymes from a partially randomized non-catalytic scaffold
-
Seelig B., and Szostak J.W. Selection and evolution of enzymes from a partially randomized non-catalytic scaffold. Nature 448 (2007) 828-831
-
(2007)
Nature
, vol.448
, pp. 828-831
-
-
Seelig, B.1
Szostak, J.W.2
-
120
-
-
0034566364
-
Industrial wastewater bioreactors: sources of novel microorganisms for biotechnology
-
Bramucci M.G., and Nagarajan V. Industrial wastewater bioreactors: sources of novel microorganisms for biotechnology. Trends Biotechnol. 18 (2000) 501-505
-
(2000)
Trends Biotechnol.
, vol.18
, pp. 501-505
-
-
Bramucci, M.G.1
Nagarajan, V.2
-
121
-
-
34249881329
-
Microbial metagenomes: moving forward industrial biotechnology
-
Ferrer M., et al. Microbial metagenomes: moving forward industrial biotechnology. J. Chem. Technol. Biotechnol. 82 (2007) 421-423
-
(2007)
J. Chem. Technol. Biotechnol.
, vol.82
, pp. 421-423
-
-
Ferrer, M.1
-
122
-
-
0042313850
-
The Impact of non-cultivated biodiversity on enzyme discovery and evolution
-
Lorenz P., et al. The Impact of non-cultivated biodiversity on enzyme discovery and evolution. Biocatal. Biotransform. 21 (2003) 87-91
-
(2003)
Biocatal. Biotransform.
, vol.21
, pp. 87-91
-
-
Lorenz, P.1
-
123
-
-
27844462042
-
Novel biocatalysts: recent developments
-
Bommarius A., and Polizzi K.M. Novel biocatalysts: recent developments. Chem. Eng. Sci. 61 (2005) 1004-1016
-
(2005)
Chem. Eng. Sci.
, vol.61
, pp. 1004-1016
-
-
Bommarius, A.1
Polizzi, K.M.2
-
124
-
-
27844612307
-
Extreme environments as a resource for micro-organisms and novel biocatalysts
-
Anthranikian G., et al. Extreme environments as a resource for micro-organisms and novel biocatalysts. Adv. Biochem. Eng. Biotechnol. 96 (2005) 219-262
-
(2005)
Adv. Biochem. Eng. Biotechnol.
, vol.96
, pp. 219-262
-
-
Anthranikian, G.1
-
125
-
-
11144354360
-
Environmental genome shotgun sequencing of the Sargasso sea
-
Venter J.C., et al. Environmental genome shotgun sequencing of the Sargasso sea. Science 304 (2004) 66-74
-
(2004)
Science
, vol.304
, pp. 66-74
-
-
Venter, J.C.1
-
126
-
-
19944426100
-
The enigma of prokaryotic life in deep hypersaline anoxic basins
-
van der Wielen P.W.J.J., et al. The enigma of prokaryotic life in deep hypersaline anoxic basins. Science 307 (2005) 121-123
-
(2005)
Science
, vol.307
, pp. 121-123
-
-
van der Wielen, P.W.J.J.1
-
127
-
-
34547939672
-
Structure-based activity prediction for an enzyme of unknown function
-
Herrmann J.C., et al. Structure-based activity prediction for an enzyme of unknown function. Nature 448 (2007) 775-779
-
(2007)
Nature
, vol.448
, pp. 775-779
-
-
Herrmann, J.C.1
-
128
-
-
8544253237
-
Assignment of endogenous substrates to enzymes by global metabolite profiling
-
Saghatelian A., et al. Assignment of endogenous substrates to enzymes by global metabolite profiling. Biochemistry 43 (2004) 14332-14339
-
(2004)
Biochemistry
, vol.43
, pp. 14332-14339
-
-
Saghatelian, A.1
-
129
-
-
15944426144
-
Enzyme genomics: application of general enzymatic screens to discover new enzymes
-
Kuznetsova E., et al. Enzyme genomics: application of general enzymatic screens to discover new enzymes. FEMS Microbiol. Rev. 29 (2006) 263-279
-
(2006)
FEMS Microbiol. Rev.
, vol.29
, pp. 263-279
-
-
Kuznetsova, E.1
-
130
-
-
27144443964
-
Discovery of enzymatic activity using stable isotope metabolite labeling and liquid chromatography-mass spectrometry
-
Dalluge J.J., et al. Discovery of enzymatic activity using stable isotope metabolite labeling and liquid chromatography-mass spectrometry. Anal. Chem. 77 (2005) 6737-6740
-
(2005)
Anal. Chem.
, vol.77
, pp. 6737-6740
-
-
Dalluge, J.J.1
-
131
-
-
33747169854
-
Metabolomics approach for enzyme discovery
-
Natsumi S., et al. Metabolomics approach for enzyme discovery. J. Proteome Res. 5 (2006) 1979-1987
-
(2006)
J. Proteome Res.
, vol.5
, pp. 1979-1987
-
-
Natsumi, S.1
-
132
-
-
33745756312
-
Semiquantitative process screening for the biocatalytic synthesis of d-xylulose-5-phosphate
-
Shaeri J., et al. Semiquantitative process screening for the biocatalytic synthesis of d-xylulose-5-phosphate. Org. Proc. Res. Dev. 10 (2006) 605-610
-
(2006)
Org. Proc. Res. Dev.
, vol.10
, pp. 605-610
-
-
Shaeri, J.1
-
133
-
-
55549092473
-
Characterisation of enzymatic d-xylulose 5-phosphate synthesis
-
Shaeri J., et al. Characterisation of enzymatic d-xylulose 5-phosphate synthesis. Biotech. Bioeng. 101 (2008) 761-767
-
(2008)
Biotech. Bioeng.
, vol.101
, pp. 761-767
-
-
Shaeri, J.1
-
134
-
-
67349183315
-
Synthesis of pyridoxamine 5′-phosphate using an MBA: pyruvate transaminase as biocatalyst
-
10.1016/j.molcatb.2008.10.005
-
Schell U., et al. Synthesis of pyridoxamine 5′-phosphate using an MBA: pyruvate transaminase as biocatalyst. J. Mol. Catal. B: Enzymatic (2008) 10.1016/j.molcatb.2008.10.005
-
(2008)
J. Mol. Catal. B: Enzymatic
-
-
Schell, U.1
-
135
-
-
77952472624
-
Modular and scalable biocatalytic tools for practical safety, health and environmental improvements in the production of specialty chemicals
-
Wohlgemuth R. Modular and scalable biocatalytic tools for practical safety, health and environmental improvements in the production of specialty chemicals. Biocatal. Biotransform. 25 (2007) 178-185
-
(2007)
Biocatal. Biotransform.
, vol.25
, pp. 178-185
-
-
Wohlgemuth, R.1
-
136
-
-
36248991352
-
Producing bio-based bulk chemicals using industrial biotechnology saves energy and combats climate change
-
Hermann B.G. Producing bio-based bulk chemicals using industrial biotechnology saves energy and combats climate change. Environ. Sci. Technol. 41 (2007) 7915-7921
-
(2007)
Environ. Sci. Technol.
, vol.41
, pp. 7915-7921
-
-
Hermann, B.G.1
|