Hydrolysis and photolysis of 4-acetoxy-4-(benzothiazol-2-yl)-2,5- cyclohexadien-1-one, a model anti-tumor quinol ester

Journal of Organic Chemistry

Volumn 74, Issue 12, 2009, Pages 4463-4471

  Wang, Yue Ting ^a   Kyoung, Joo Jin ^a   Myers, Lauren R ^a   Glover, Stephen A ^b   Novak, Michael ^a  

^a MIAMI UNIVERSITY   (United States)

^b UNIVERSITY OF NEW ENGLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-TUMOR; ANTI-TUMOR ACTIVITIES; ANTI-TUMOR AGENTS; AQUEOUS ENVIRONMENT; AQUEOUS SOLUTIONS; B3LYP/6-31G; BENZOTHIAZOLE; BENZOTHIAZOLE DERIVATIVES; CANCER CELL LINES; CHEMICAL EQUATIONS; ELECTRON-DONATING; ELECTRON-WITHDRAWING EFFECTS; HUMAN BREAST; P-TOLYL; PHOTOLYSIS PRODUCTS; POSITIVE CHARGES; REACTIVE INTERMEDIATE; RESONANCE EFFECT;

CELL CULTURE; DERIVATIVES; ESTERIFICATION; ESTERS; IONIZATION; PHENOLS; PHOTOLYSIS; TUMORS;

HYDROLYSIS;

1,8 BIS(BENZOTHIAZOL 2 YL) 4,5 DIOXO 1,4,4A,4B,5,8,8A,8B OCTAHYDROBIPHENYLENE 1,8 DIYL DIACETATE; 2 (4 AMINOPHENYL)BENZOTHIAZOLE; 4 (6 AZIDOBENZOTHIAZOL 2 YL)PHENOL; 4 (BENZOTHIAZOL 2 YL) 2 METHYLPHENOL; 4 (BENZOTHIAZOL 2 YL) 4 (METHYLPEROXY)CYCLOHEXA 2,5 DIENONE; 4 (BENZOTHIAZOL 2 YL) 4 HYDROXY 2,5 CYCLOHEXADIEN 1 ONE; 4 ACETOXY 3 (BENZOTHIAZOL 2 YL)PHENOL; 4 ACETOXY 4 (BENZOTHIAZOL 2 YL) 2,5 CYCLOHEXADIEN 1 ONE; ANTINEOPLASTIC AGENT; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CANCER CELL; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROLYSIS; IONIZATION; PHOTOLYSIS; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTINEOPLASTIC AGENTS; BENZOTHIAZOLES; CYCLOHEXANONES; ESTERS; HYDROLYSIS; HYDROQUINONES; KINETICS; PHOTOLYSIS; THERMODYNAMICS;

EID: 67249131671     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo9008436     Document Type: Article

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