Antitumor quinols: Role of glutathione in modulating quinol-induced apoptosis and identification of putative cellular protein targets

Biochemical and Biophysical Research Communications

Volumn 346, Issue 1, 2006, Pages 242-251

  Chew, Eng Hui ^a   Matthews, Charles S ^a   Zhang, Jihong ^a   McCarroll, Andrew J ^a   Hagen, Thilo ^a   Stevens, Malcolm F G ^a   Westwell, Andrew D ^a   Bradshaw, Tracey D ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Apoptosis induction; BSO; Glutathione; Quinols

Indexed keywords

4 (1 BENZENESULFONYL 1H INDOL 2 YL) 4 HYDROXYCYCLOHEXA 2,5 DIENONE; 4 (BENZOTHIAZOL 2 YL) 4 HYDROXYCYCLOHEXA 2,5 DIENONE; ANTINEOPLASTIC AGENT; ANTIOXIDANT; AW 464; BETA TUBULIN; BUTHIONINE SULFOXIMINE; BW 114; CASPASE 3; CELL PROTEIN; GLUTATHIONE; GLUTATHIONE ETHYL ESTER; HEAT SHOCK PROTEIN 60; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PEROXIREDOXIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL STRAIN HCT116; CELL STRAIN HT29; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG POTENCY; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BENZOTHIAZOLES; CASPASE 3; CASPASES; CELL LINE, TUMOR; CYCLOHEXANONES; GLUTATHIONE; HUMANS; HYDROQUINONES; POLY(ADP-RIBOSE) POLYMERASES; REACTIVE OXYGEN SPECIES; SULFONES; THIAZOLES;

EID: 33744983297     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.05.106     Document Type: Article

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