Antitumour benzothiazoles. Part 10: The synthesis and antitumour activity of benzothiazole substituted quinol derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 5, 2000, Pages 513-515

  Wells, Geoffrey ^a   Bradshaw, Tracey D ^a   Diana, Patrizia ^a   Seaton, Angela ^a   Shi, Dong Fang ^a   Westwell, Andrew D ^a   Stevens, Malcolm F G ^a  

^a Theoretical Mechanics Section   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 (3 HYDROXYPHENYL)BENZOTHIAZOLE; 2 (4 HYDROXYPHENYL)BENZOTHIAZOLE; 6 HYDROXY 2 PHENYLBENZOTHIAZOLE; BENZOTHIAZOLE DERIVATIVE; ESTER; ETHER; IODOBENZENE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CHEMICAL MODIFICATION; COLON CANCER; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; OXIDATION; TUMOR CELLS AND CELL LINES;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; COLONIC NEOPLASMS; DRUG SCREENING ASSAYS, ANTITUMOR; HT29 CELLS; HUMANS; HYDROQUINONES; OXIDATION-REDUCTION; THIAZOLES; TUMOR CELLS, CULTURED;

EID: 0034611437     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00027-5     Document Type: Article

References (14)

1. Pelter, A.; Elgendy, S. M. A. J. Chem. Soc. Perkin Trans. 1, 1993, 1891.
2. Rambas L., McMurray J.S., Budde R.J.A. Cancer Res. 54:1994;867.
3. Wells, G. PhD thesis, University of Nottingham, 1998.
4. Stevens M.F.G., McCall C.J., Lelieveld P., Alexander P., Richter A., Davies D.E. J. Med. Chem. 37:1994;1689.
5. Wells, G.; Seaton, A.; Stevens, M. F. G. J. Med. Chem., in press.
6. Bradshaw T.D., Wrigley S., Shi D.-F., Schultz R.J., Paull K.D., Stevens M.F.G. Brit. J. Cancer. 77:1998;745.
7. Ben-Allum A., Bakkas S., Soufiaoui M. Tetrahedron Lett. 38:1997;6395.
8. 2), 2.57 (1H, t, J 2.5 Hz, CCH).
9. Mitchell A.S., Russell R.A. Tetrahedron Lett. 34:1993;545.
10. Callinan A., Chen Y., Morrow G.W., Swenton J.S. Tetrahedron Lett. 31:1990;4551.
11. DeSchepper R.E., Swenton J.S. Tetrahedron Lett. 26:1985;4831.
12. 3O).
13. Shi, D.-F. PhD thesis, University of Nottingham, 1995.
14. 3).