Stereocontrolled conjugate additions to dihydroindolizinone systems. Synthesis of enantiopure polysubstituted tetrahydropyrrolo[2,1-a]isoquinolones

Tetrahedron

Volumn 65, Issue 29-30, 2009, Pages 5787-5798

  Camarero, Cristina ^a   González Temprano, Inés ^a   Gómez SanJuan, Asier ^a   Arrasate, Sonia ^a   Lete, Esther ^a   Sotomayor, Nuria ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

1 (1,3 DITHIAN 2 YL) 8,9 DIMETHOXY 10B METHYL 1,5,6,10B TETRAHYDROPYRROLO[2,1 A]ISOQUINOLIN 3 ONE; 1 BENZYLAMINO 2 N BENZYLCARBAMOYL 10B METHYL 8,9 DIMETHOXY 1,5,6,10B TETRAHYDROPYRROLO[2,1 A]ISOQUINOLIN 3 ONE; 1 BUTYL 2 [BIS(THIOPHENYL)METHYL] 8,9 DIMETHOXY 1,5,6,10B TETRAHYDROPYRROLO[2,1 A]ISOQUINOLIN 3 ONE; 1 BUTYL 2 BUTOXYCARBONYL 8,9 DIMETHOXY 10B METHYL 1,5,6,10B TETRAHYDROPYRROLO[2,1 A]ISOQUINOLIN 3 ONE; 1,10B DIBUTYL 2 BUTOXYCARBONYL 8,9 DIMETHOXY 1,5,6,10B TETRAHYDROPYRROLO[2,1 A]ISOQUINOLIN 3 ONE; 10B BUTYL 2 BUTOXYCARBONYL 8,9 DIMETHOXY 1 METHYL 1,5,6,10B TETRAHYDROPYRROLO[2,1 A]ISOQUINOLIN 3 ONE; 10B BUTYL 8,9 DIMETHOXY 1 METHYL 1,5,6,10B TETRAHYDROPYRROLO[2,1 A]ISOQUINOLIN 3 ONE; 2 (2 HYDROXY 7,7 DIMETHYLBICYCLO[2.2.1]HEPTAN 1 YLMETHYLSULFINYL) 8,9 DIMETHOXY 1,10B DIMETHYL 1,5,6,10B TETRAHYDROPYRROLO[2,1 A]ISOQUINOLIN 3 ONE; 2 ALLYL 2 BENZYLOXYCARBONYL 8,9 DIMETHOXY 1,10B DIMETHYL 1,5,6,10B TETRAHYDROPYRROLO[2,1 A]ISOQUINOLIN 3 ONE; 2 BENZYLCARBONYL 1 (1,1,1,3,3,3 HEXAMETHYLDISILAZAN 2 YL) 10B METHYL 8,9 DIMETHOXY 1,5,6,10B TETRAHYDROPYRROLO[2,1 A]ISOQUINOLIN 3 ONE; 2 BENZYLOXYCARBONYL 1 (CYANOMETHOXYCARBONYLMETHYL) 8,9 DIMETHOXY 10B METHYL 1,5,6,10B TETRAHYDROPYRROLO[2,1 A]ISOQUINOLIN 3 ONE; 2 BENZYLOXYCARBONYL 1 [BIS(METHOXYCARBONYL)METHYL] 10B BUTYL 8,9 DIMETHOXY 1,5,6,10B TETRAHYDROPYRROLO[2,1 A]ISOQUINOLIN 3 ONE; 2 BENZYLOXYCARBONYL 1 [BIS(METHOXYCARBONYL)METHYL] 8,9 DIMETHOXY 10B METHYL 1,5,6,10B TETRAHYDROPYRROLO[2,1 A]ISOQUINOLIN 3 ONE; 2 BENZYLOXYCARBONYL 1 BUTYL 8,9 DIMETHOXY 10B METHYL 1,5,6,10B TETRAHYDROPYRROLO[2,1 A]ISOQUINOLIN 3 ONE; 2 BENZYLOXYCARBONYL 1,10B DIBUTYL 8,9 DIMETHOXY 1,5,6,10B TETRAHYDROPYRROLO[2,1 A]ISOQUINOLIN 3 ONE; 2 BENZYLOXYCARBONYL 10B BUTYL 1 (CYANOMETHOXYCARBONYLMETHYL) 8,9 DIMETHOXY 1,5,6,10B TETRAHYDROPYRROLO[2,1 A]ISOQUINOLIN 3 ONE; 2 BENZYLOXYCARBONYL 10B BUTYL 8,9 DIMETHOXY 1 METHYL 1,5,6,10B TETRAHYDROPYRROLO[2,1 A]ISOQUINOLIN 3 ONE; 2 BENZYLOXYCARBONYL 8,9 DIMETHOXY 1,10B DIMETHYL 1,5,6,10B TETRAHYDROPYRROLO[2,1 A]ISOQUINOLIN 3 ONE; 2 BENZYLOXYCARBONYL 8,9 DIMETHOXY 1,2,10B TRIMETHYL 1,5,6,10B TETRAHYDROPYRROLO[2,1 A]ISOQUINOLIN 3 ONE; 2 BUTOXYCARBONYL 10B BUTYL 8,9 DIMETHOXY 5,6 DIHYDROPYRROLO[2,1 A]ISOQUINOLIN 3 ONE; 8,9 DIMETHOXY 1,10B DIMETHYL 1,5,6,10B TETRAHYDROPYRROLO[2,1 A]ISOQUINOLIN 3 ONE; ISOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; MICHAEL ADDITION; PRIORITY JOURNAL; STEREOCHEMISTRY; SUBSTITUTION REACTION;

EID: 66949146092     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2009.05.011     Document Type: Article

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