Conformationally Constrained Dipeptide Surrogates with Aromatic Side-Chains: Synthesis of 4-Aryl Indolizidin-9-one Amino Acids by Conjugate Addition to a Common α,ω-Diaminoazelate Enone Intermediate

Journal of Organic Chemistry

Volumn 69, Issue 5, 2004, Pages 1504-1512

  Cluzeau, Jérôme ^a   Lubell, William D ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADDITION REACTIONS; AMINATION; AMINO ACIDS; CONFORMATIONS; ESTERS; HYDROGENATION; HYDROLYSIS; STEREOCHEMISTRY;

CONFORMATION ACTIVITY; CYCLIZATION;

SYNTHESIS (CHEMICAL);

4 PHENYLINDOLIZIDIN 9 ONE N (BUTYLOXYCARBONYL)AMINO ACID; 6 PHENYLAZELATE DERIVATIVE; 9 OXO 8 [N (BUTOXYCARBONYL)AMINO] 4 PHENYL 1 AZABICYCLO[4.3.0]NONANE CARBOXYLATE; ALPHA,OMEGA DIAMINOAZELATE; AMINO ACID; AMMONIUM ACETATE; AZELAIC ACID; CARBOXYLIC ACID DERIVATIVE; DIPEPTIDE; INDOLIZIDINE DERIVATIVE; PIPECOLIC ACID; UNCLASSIFIED DRUG;

ADDITION REACTION; AMINATION; ARTICLE; CHEMICAL ANALYSIS; CHROMATOGRAPHY; CONFORMATION; CYCLIZATION; GRIGNARD REACTION; HYDROGENATION; PROTEIN CONFORMATION; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

AMINATION; AMINO ACIDS; DICARBOXYLIC ACIDS; DIPEPTIDES; HYDROCARBONS, AROMATIC; HYDROGENATION; INDOLIZINES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR MIMICRY; MOLECULAR STRUCTURE; STEREOISOMERISM;

EID: 1442275544     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0355855     Document Type: Article

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