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Volumn 42, Issue 4, 2009, Pages 185-188

UAP56- a key player with surprisingly diverse roles in pre-mRNA splicing and nuclear export

Author keywords

MRNA nuclear export; Pre mRNA splicing; UAP56

Indexed keywords

BAT1 PROTEIN, HUMAN; DEAD BOX PROTEIN;

EID: 66849083719     PISSN: 19766696     EISSN: 1976670X     Source Type: Journal    
DOI: 10.5483/BMBRep.2009.42.4.185     Document Type: Short Survey
Times cited : (55)

References (49)
  • 1
    • 0030611640 scopus 로고    scopus 로고
    • U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction
    • Fleckner, J., Zhang, M., Valcarcel, J. and Green, M. R. (1997) U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction. Genes Dev. 11, 1864-1872.
    • (1997) Genes Dev. , vol.11 , pp. 1864-1872
    • Fleckner, J.1    Zhang, M.2    Valcarcel, J.3    Green, M.R.4
  • 2
    • 46249107277 scopus 로고    scopus 로고
    • Distinct activities of the DExD/H-box splicing factor hUAP56 facilitate stepwise assembly of the spliceosome
    • Shen, H., Zheng, X., Shen, J., Zhang, L., Zhao, R. and Green, M. R. (2008) Distinct activities of the DExD/H-box splicing factor hUAP56 facilitate stepwise assembly of the spliceosome. Genes Dev. 22, 1796-1803.
    • (2008) Genes Dev. , vol.22 , pp. 1796-1803
    • Shen, H.1    Zheng, X.2    Shen, J.3    Zhang, L.4    Zhao, R.5    Green, M.R.6
  • 3
    • 34547931108 scopus 로고    scopus 로고
    • Biochemical characterization of the ATPase and helicase activity of UAP56, an essential pre-mRNA splicing and mRNA export factor
    • Shen, J., Zhang, L. and Zhao, R. (2007) Biochemical characterization of the ATPase and helicase activity of UAP56, an essential pre-mRNA splicing and mRNA export factor. J. Biol. Chem. 282, 22544-22550.
    • (2007) J. Biol. Chem. , vol.282 , pp. 22544-22550
    • Shen, J.1    Zhang, L.2    Zhao, R.3
  • 4
    • 0035177309 scopus 로고    scopus 로고
    • Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for sub2, an essential spliceosomal ATPase
    • Kistler, A. L. and Guthrie, C. (2001) Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for sub2, an essential spliceosomal ATPase. Genes Dev. 15, 42-49.
    • (2001) Genes Dev. , vol.15 , pp. 42-49
    • Kistler, A.L.1    Guthrie, C.2
  • 5
  • 6
    • 0033592896 scopus 로고    scopus 로고
    • Splicing is required for rapid and efficient mRNA export in metazoans
    • Luo, M-J. and Reed, R. (1999) Splicing is required for rapid and efficient mRNA export in metazoans. Proc. Natl. Acad. Sci. U.S.A. 96, 14937-14942.
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 14937-14942
    • Luo, M.-J.1    Reed, R.2
  • 7
    • 0035846138 scopus 로고    scopus 로고
    • Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly
    • Luo, M. L., Zhou, Z., Magni, K., Christoforides, C., Rappsilber, J., Mann, M. and Reed, R. (2001) Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly. Nature 413, 644-647.
    • (2001) Nature , vol.413 , pp. 644-647
    • Luo, M.L.1    Zhou, Z.2    Magni, K.3    Christoforides, C.4    Rappsilber, J.5    Mann, M.6    Reed, R.7
  • 8
    • 39249083167 scopus 로고    scopus 로고
    • UAP56 RNA helicase is required for axis specification and cytoplasmic mRNA localization in Drosophila
    • Meignin, C. and Davis, I. (2008) UAP56 RNA helicase is required for axis specification and cytoplasmic mRNA localization in Drosophila. Dev. Biol. 315, 89-98.
    • (2008) Dev. Biol. , vol.315 , pp. 89-98
    • Meignin, C.1    Davis, I.2
  • 9
    • 4143076853 scopus 로고    scopus 로고
    • Crystal structure of UAP56, a DExD/H-box protein involved in pre-mRNA splicing and mRNA export
    • Zhao, R., Shen, J., Green, M. R., MacMorris, M. and Blumenthal, T. (2004) Crystal structure of UAP56, a DExD/H-box protein involved in pre-mRNA splicing and mRNA export. Structure 12, 1373-1381.
    • (2004) Structure , vol.12 , pp. 1373-1381
    • Zhao, R.1    Shen, J.2    Green, M.R.3    MacMorris, M.4    Blumenthal, T.5
  • 10
    • 0010456859 scopus 로고    scopus 로고
    • Crystal structure of the ATPase domain of translation initiation factor 4A from Saccharo- myces cerevisiae - the prototype of the DEAD box protein family
    • Benz, J., Trachsel, H. and Baumann, U. (1999) Crystal structure of the ATPase domain of translation initiation factor 4A from Saccharo- myces cerevisiae - the prototype of the DEAD box protein family. Struct. Fold. Des. 7, 671-679.
    • (1999) Struct. Fold. Des. , vol.7 , pp. 671-679
    • Benz, J.1    Trachsel, H.2    Baumann, U.3
  • 13
    • 0033762534 scopus 로고    scopus 로고
    • Selection of alternative 5' splice sites: role of U1 snRNP and models for the antagonistic effects of SF2/ASF and hnRNP A1
    • Eperon, I. C., Makarova, O. V., Mayeda, A., Munroe, S. H., Caceres, J. F., Hayward, D. G. and Krainer, A. R. (2000) Selection of alternative 5' splice sites: role of U1 snRNP and models for the antagonistic effects of SF2/ASF and hnRNP A1. Mol. Cell Biol. 20, 8303-8318.
    • (2000) Mol. Cell Biol. , vol.20 , pp. 8303-8318
    • Eperon, I.C.1    Makarova, O.V.2    Mayeda, A.3    Munroe, S.H.4    Caceres, J.F.5    Hayward, D.G.6    Krainer, A.R.7
  • 14
    • 14744290800 scopus 로고    scopus 로고
    • RS domains contact the pre-mRNA throughout spliceosome assembly
    • Hertel, K. J. and Graveley, B. R. (2005) RS domains contact the pre-mRNA throughout spliceosome assembly. Trends Biochem. Sci. 30, 115-118.
    • (2005) Trends Biochem. Sci. , vol.30 , pp. 115-118
    • Hertel, K.J.1    Graveley, B.R.2
  • 15
    • 0033557806 scopus 로고    scopus 로고
    • Pre-mRNA splicing of IgM exons M1 and M2 is directed by a juxtaposed splicing enhancer and inhibitor
    • Kan, J. L. and Green, M. R. (1999) Pre-mRNA splicing of IgM exons M1 and M2 is directed by a juxtaposed splicing enhancer and inhibitor. Genes Dev. 13, 462-471.
    • (1999) Genes Dev. , vol.13 , pp. 462-471
    • Kan, J.L.1    Green, M.R.2
  • 16
    • 1242316952 scopus 로고    scopus 로고
    • Arginine-serine-rich domains bound at splicing enhancers contact the branchpoint to promote prespliceosome assembly
    • Shen, H., Kan, J. L. and Green, M. R. (2004) Arginine-serine-rich domains bound at splicing enhancers contact the branchpoint to promote prespliceosome assembly. Mol. Cell 13, 367-376.
    • (2004) Mol. Cell , vol.13 , pp. 367-376
    • Shen, H.1    Kan, J.L.2    Green, M.R.3
  • 17
    • 34447130937 scopus 로고    scopus 로고
    • RS domain-splicing signal interactions in splicing of U12-type and U2-type introns
    • Shen, H. and Green, M. R. (2007) RS domain-splicing signal interactions in splicing of U12-type and U2-type introns. Nat. Struct. Mol. Biol. 14, 597-603.
    • (2007) Nat. Struct. Mol. Biol. , vol.14 , pp. 597-603
    • Shen, H.1    Green, M.R.2
  • 18
    • 33745609509 scopus 로고    scopus 로고
    • RS domains contact splicing signals and promote splicing by a common mechanism in yeast through humans
    • Shen, H. and Green, M. R. (2006) RS domains contact splicing signals and promote splicing by a common mechanism in yeast through humans. Genes Dev. 20, 1755-1765.
    • (2006) Genes Dev. , vol.20 , pp. 1755-1765
    • Shen, H.1    Green, M.R.2
  • 19
    • 1942501651 scopus 로고    scopus 로고
    • A single polypyrimidine tract binding protein (PTB) binding site mediates splicing inhibition at mouse IgM exons M1 and M2
    • Shen, H., Kan, J. L., Ghigna, C., Biamonti, G. and Green, M. R. (2004) A single polypyrimidine tract binding protein (PTB) binding site mediates splicing inhibition at mouse IgM exons M1 and M2. RNA 10, 787-794.
    • (2004) RNA , vol.10 , pp. 787-794
    • Shen, H.1    Kan, J.L.2    Ghigna, C.3    Biamonti, G.4    Green, M.R.5
  • 20
    • 0036544654 scopus 로고    scopus 로고
    • Disruption of an SF2/ASF-dependent exonic splicing enhancer in SMN2 causes spinal muscular atrophy in the absence of SMN1
    • Cartegni, L. and Krainer, A. R. (2002) Disruption of an SF2/ASF-dependent exonic splicing enhancer in SMN2 causes spinal muscular atrophy in the absence of SMN1. Nat. Genet. 30, 377-384.
    • (2002) Nat. Genet. , vol.30 , pp. 377-384
    • Cartegni, L.1    Krainer, A.R.2
  • 21
    • 4444272979 scopus 로고    scopus 로고
    • Cell signalling and the control of pre-mRNA splicing
    • Shin, C. and Manley, J. L. (2004) Cell signalling and the control of pre-mRNA splicing. Nat. Rev. Mol. Cell Biol. 5, 727-738.
    • (2004) Nat. Rev. Mol. Cell Biol. , vol.5 , pp. 727-738
    • Shin, C.1    Manley, J.L.2
  • 22
    • 33344473656 scopus 로고    scopus 로고
    • The DEAD-box protein family of RNA helicases
    • Cordin, O., Banroques, J., Tanner, N. K. and Linder, P. (2006) The DEAD-box protein family of RNA helicases. Gene 367, 17-37.
    • (2006) Gene , vol.367 , pp. 17-37
    • Cordin, O.1    Banroques, J.2    Tanner, N.K.3    Linder, P.4
  • 24
    • 0032515969 scopus 로고    scopus 로고
    • The human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplices in vitro
    • Laggerbauer, B., Achsel, T. and Luhrmann, R. (1998) The human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplices in vitro. Proc. Natl. Acad. Sci. U.S.A. 95, 4188-4192.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 4188-4192
    • Laggerbauer, B.1    Achsel, T.2    Luhrmann, R.3
  • 25
    • 33749139723 scopus 로고    scopus 로고
    • Dead-box proteins: a family affair-active and passive players in RNP-remodeling
    • Linder, P. (2006) Dead-box proteins: a family affair-active and passive players in RNP-remodeling. Nucleic. Acids Res. 34, 4168-4180.
    • (2006) Nucleic. Acids Res. , vol.34 , pp. 4168-4180
    • Linder, P.1
  • 26
    • 0032537739 scopus 로고    scopus 로고
    • RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2
    • Raghunathan, P. L. and Guthrie, C. (1998) RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2. Curr. Biol. 8, 847-855.
    • (1998) Curr. Biol. , vol.8 , pp. 847-855
    • Raghunathan, P.L.1    Guthrie, C.2
  • 27
    • 1542344429 scopus 로고    scopus 로고
    • DEAD-box proteins: the driving forces behind RNA metabolism
    • Rocak, S. and Linder, P. (2004) DEAD-box proteins: the driving forces behind RNA metabolism. Nat. Rev. Mol. Cell Biol. 5, 232-241.
    • (2004) Nat. Rev. Mol. Cell Biol. , vol.5 , pp. 232-241
    • Rocak, S.1    Linder, P.2
  • 28
    • 33646017369 scopus 로고    scopus 로고
    • Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa
    • Sengoku, T., Nureki, O., Nakamura, A., Kobayashi, S. and Yokoyama, S. (2006) Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa. Cell 125, 287-300.
    • (2006) Cell , vol.125 , pp. 287-300
    • Sengoku, T.1    Nureki, O.2    Nakamura, A.3    Kobayashi, S.4    Yokoyama, S.5
  • 29
    • 0141430073 scopus 로고    scopus 로고
    • DExD/H-box proteins and their partners: helping RNA helicases unwind
    • Silverman, E., Edwalds-Gilbert, G. and Lin, R. J. (2003) DExD/H-box proteins and their partners: helping RNA helicases unwind. Gene 312, 1-16.
    • (2003) Gene , vol.312 , pp. 1-16
    • Silverman, E.1    Edwalds-Gilbert, G.2    Lin, R.J.3
  • 30
    • 0032489021 scopus 로고    scopus 로고
    • Mechanical devices of the spliceosome: motors, clocks, springs, and things
    • Staley, J. P. and Guthrie, C. (1998) Mechanical devices of the spliceosome: motors, clocks, springs, and things. Cell 92, 315-326.
    • (1998) Cell , vol.92 , pp. 315-326
    • Staley, J.P.1    Guthrie, C.2
  • 31
    • 0032525149 scopus 로고    scopus 로고
    • The DEAH-box protein PRP22 is an ATPase that mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes
    • Wagner, J. D., Jankowsky, E., Company, M., Pyle, A. M. and Abelson, J. N. (1998) The DEAH-box protein PRP22 is an ATPase that mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes. EMBO J. 17, 2926-2937.
    • (1998) EMBO J. , vol.17 , pp. 2926-2937
    • Wagner, J.D.1    Jankowsky, E.2    Company, M.3    Pyle, A.M.4    Abelson, J.N.5
  • 32
    • 0032499075 scopus 로고    scopus 로고
    • The DEAH-box splicing factor Prp16 unwinds RNA duplexes in vitro
    • Wang, Y., Wagner, J. D. and Guthrie, C. (1998) The DEAH-box splicing factor Prp16 unwinds RNA duplexes in vitro. Curr. Biol. 8, 441-451.
    • (1998) Curr. Biol. , vol.8 , pp. 441-451
    • Wang, Y.1    Wagner, J.D.2    Guthrie, C.3
  • 33
    • 0035187881 scopus 로고    scopus 로고
    • Identification and characterization of yUAP/Sub2p, a yeast homolog of the essential human pre-mRNA splicing factor hUAP56
    • Zhang, M. and Green, M. R. (2001) Identification and characterization of yUAP/Sub2p, a yeast homolog of the essential human pre-mRNA splicing factor hUAP56. Genes Dev. 15, 30-35.
    • (2001) Genes Dev. , vol.15 , pp. 30-35
    • Zhang, M.1    Green, M.R.2
  • 36
    • 33845626622 scopus 로고    scopus 로고
    • Human mRNA export machinery recruited to the 5_ end of mRNA
    • Cheng, H., Dufu, K., Lee, C. S., Hsu, J. L., Dias, A. and Reed, R. (2006) Human mRNA export machinery recruited to the 5_ end of mRNA. Cell 127, 1389-1400.
    • (2006) Cell , vol.127 , pp. 1389-1400
    • Cheng, H.1    Dufu, K.2    Lee, C.S.3    Hsu, J.L.4    Dias, A.5    Reed, R.6
  • 37
    • 0037062982 scopus 로고    scopus 로고
    • Alternative pre-mRNA splicing and proteome expansion in metazoans
    • Maniatis, T. and Tasic, B. (2002) Alternative pre-mRNA splicing and proteome expansion in metazoans. Nature 418, 236-243.
    • (2002) Nature , vol.418 , pp. 236-243
    • Maniatis, T.1    Tasic, B.2
  • 38
    • 42449084129 scopus 로고    scopus 로고
    • Protein factors in pre-mRNA 3'-end processing
    • Mandel, C. R., Bai, Y. and Tong, L. (2008) Protein factors in pre-mRNA 3'-end processing. Cell Mol. Life Sci. 65, 1099-1122.
    • (2008) Cell Mol. Life Sci. , vol.65 , pp. 1099-1122
    • Mandel, C.R.1    Bai, Y.2    Tong, L.3
  • 39
    • 0035975969 scopus 로고    scopus 로고
    • The DECD box putative ATPase Sub2p is an early mRNA export factor
    • Jensen, T. H., Boulay, J., Rosbash, M. and Libri, D. (2001) The DECD box putative ATPase Sub2p is an early mRNA export factor. Curr. Biol. 11, 1711-1715.
    • (2001) Curr. Biol. , vol.11 , pp. 1711-1715
    • Jensen, T.H.1    Boulay, J.2    Rosbash, M.3    Libri, D.4
  • 40
  • 41
    • 0035960716 scopus 로고    scopus 로고
    • mRNA export: travelling with DEAD box proteins
    • Linder, P. and Stutz, F. (2001) mRNA export: travelling with DEAD box proteins. Curr. Biol. 11, R961-963.
    • (2001) Curr. Biol. , vol.11
    • Linder, P.1    Stutz, F.2
  • 43
    • 0037076221 scopus 로고    scopus 로고
    • HEL/UAP56 binds cotranscriptionally to the Balbiani ring pre-mRNA in an intron-independent manner and accompanies the BR mRNP to the nuclear pore
    • Kiesler, E., Miralles, F. and Visa, N. (2002) HEL/UAP56 binds cotranscriptionally to the Balbiani ring pre-mRNA in an intron-independent manner and accompanies the BR mRNP to the nuclear pore. Curr. Biol. 12, 859-862.
    • (2002) Curr. Biol. , vol.12 , pp. 859-862
    • Kiesler, E.1    Miralles, F.2    Visa, N.3
  • 44
    • 0037566678 scopus 로고    scopus 로고
    • Genomewide analysis of nuclear mRNA export pathways in Drosophila
    • Herold, A., Teixeira, L. and Izaurralde, E. (2003) Genomewide analysis of nuclear mRNA export pathways in Drosophila. EMBO J. 22, 2472-2483.
    • (2003) EMBO J. , vol.22 , pp. 2472-2483
    • Herold, A.1    Teixeira, L.2    Izaurralde, E.3
  • 45
    • 0038719952 scopus 로고    scopus 로고
    • UAP56 levels affect viability and mRNA export in Caenorhabditis elegans
    • MacMorris, M., Brocker, C. and Blumenthal, T. (2003) UAP56 levels affect viability and mRNA export in Caenorhabditis elegans. RNA 9, 847-857.
    • (2003) RNA , vol.9 , pp. 847-857
    • MacMorris, M.1    Brocker, C.2    Blumenthal, T.3
  • 46
    • 34547099097 scopus 로고    scopus 로고
    • The nuclear export signal of splicing factor Uap56p interacts with nuclear pore-associated protein Rae1p for mRNA export in Schizosaccharomyces pombe
    • Thakurta, A. G., Selvanathan, S. P., Patterson, A. D., Gopal, G. and Dhar, R. (2007) The nuclear export signal of splicing factor Uap56p interacts with nuclear pore-associated protein Rae1p for mRNA export in Schizosaccharomyces pombe. J. Biol. Chem. 282, 17507-17516.
    • (2007) J. Biol. Chem. , vol.282 , pp. 17507-17516
    • Thakurta, A.G.1    Selvanathan, S.P.2    Patterson, A.D.3    Gopal, G.4    Dhar, R.5
  • 47
    • 37849054264 scopus 로고    scopus 로고
    • ATP-dependent recruitment of export factor Aly/REF onto intronless mRNAs by RNA helicase UAP56
    • Taniguchi, I. and Ohno, M. (2008) ATP-dependent recruitment of export factor Aly/REF onto intronless mRNAs by RNA helicase UAP56. Mol. Cell Biol. 28, 601-608.
    • (2008) Mol. Cell Biol. , vol.28 , pp. 601-608
    • Taniguchi, I.1    Ohno, M.2
  • 48
    • 39249083167 scopus 로고    scopus 로고
    • UAP56 RNA helicase is required for axis specification and cytoplasmic mRNA localization in Drosophila
    • Meignin, C. and Davis, I. (2008) UAP56 RNA helicase is required for axis specification and cytoplasmic mRNA localization in Drosophila. Dev. Biol. 315, 89-98.
    • (2008) Dev. Biol. , vol.315 , pp. 89-98
    • Meignin, C.1    Davis, I.2
  • 49
    • 0036826885 scopus 로고    scopus 로고
    • 5' exon interactions within the human spliceosome establish a framework for exon junction complex structure and assembly
    • Reichert, V. L., Le Hir, H., Jurica, M. S. and Moore, M. J. (2002) 5' exon interactions within the human spliceosome establish a framework for exon junction complex structure and assembly. Genes Dev. 16, 2778-2791.
    • (2002) Genes Dev. , vol.16 , pp. 2778-2791
    • Reichert, V.L.1    Le Hir, H.2    Jurica, M.S.3    Moore, M.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.