-
1
-
-
0020632173
-
Identification of a hypoxic population of bone marrow cells
-
Allalunis, M.J., Chapman, J.D. and Turner, A.R. 1983. Identification of a hypoxic population of bone marrow cells. Int. J. Radiat. Oncol. Biol. Phys, 9:227-32.
-
(1983)
Int. J. Radiat. Oncol. Biol. Phys
, vol.9
, pp. 227-232
-
-
Allalunis, M.J.1
Chapman, J.D.2
Turner, A.R.3
-
2
-
-
36549088609
-
HIF1α regulation of Sox9 is necessary to maintain differentiation of hypoxic prechondrogenic cells during early skeletogenesis
-
Amarilio, R., Viukov, S.V., Sharir, A., Eshkar-Oren, I., Johnson, R.S. and Zelzer, E, 2007. HIF1α regulation of Sox9 is necessary to maintain differentiation of hypoxic prechondrogenic cells during early skeletogenesis. Development, 134:3917-28.
-
(2007)
Development
, vol.134
, pp. 3917-3928
-
-
Amarilio, R.1
Viukov, S.V.2
Sharir, A.3
Eshkar-Oren, I.4
Johnson, R.S.5
Zelzer, E.6
-
3
-
-
34247582208
-
Evolution. Oxygen and evolution
-
Berner, R. A., Vandenbrooks, J.M. and Ward, P.D. 2007. Evolution. Oxygen and evolution. Science, 316:557-8.
-
(2007)
Science
, vol.316
, pp. 557-558
-
-
Berner, R.A.1
Vandenbrooks, J.M.2
Ward, P.D.3
-
4
-
-
0015076322
-
Oxygen tension in zones of the epiphyseal plate, the metaphysis and diaphysis. An in vitro and in vivo study in rats and rabbits
-
Brighton, C.T. and Heppenstall, R.B. 1971a. Oxygen tension in zones of the epiphyseal plate, the metaphysis and diaphysis. An in vitro and in vivo study in rats and rabbits. J. Bone Joint Surg., 53:719-28.
-
(1971)
J. Bone Joint Surg
, vol.53
, pp. 719-728
-
-
Brighton, C.T.1
Heppenstall, R.B.2
-
5
-
-
0015130399
-
Oxygen tension of the epiphyseal plate distal to an arteriovenous fistula
-
Brighton, C.T. and Heppenstall, R.B. 1971b. Oxygen tension of the epiphyseal plate distal to an arteriovenous fistula. Clin. Orthop. Rel. Res., 80:167-73.
-
(1971)
Clin. Orthop. Rel. Res
, vol.80
, pp. 167-173
-
-
Brighton, C.T.1
Heppenstall, R.B.2
-
6
-
-
0034100836
-
Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFβ3
-
Caniggia, I., Mostachfi, H., Winter, J., Gassmann, M., Lye, S.J., Kuliszewski, M. and Post, M. 2000. Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFβ3. J. Clin. Invest., 105:577-87.
-
(2000)
J. Clin. Invest
, vol.105
, pp. 577-587
-
-
Caniggia, I.1
Mostachfi, H.2
Winter, J.3
Gassmann, M.4
Lye, S.J.5
Kuliszewski, M.6
Post, M.7
-
7
-
-
0032581277
-
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
-
Carmeliet, P., Dor, Y., Herbert, J.M., Fukumura, D., Brusselmans, K., Dewerchin, M., Neeman, M., Bono, F., Abramovitch, R., Maxwell, P. et al. 1998. Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature, 394:485-90.
-
(1998)
Nature
, vol.394
, pp. 485-490
-
-
Carmeliet, P.1
Dor, Y.2
Herbert, J.M.3
Fukumura, D.4
Brusselmans, K.5
Dewerchin, M.6
Neeman, M.7
Bono, F.8
Abramovitch, R.9
Maxwell, P.10
-
8
-
-
4043184065
-
Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
-
Ceradini, D.J., Kulkarni, A.R., Callaghan, M.J., Tepper, O.M., Bastidas, N., Kleinman, M.E., Capla, J.M., Galiano, R.D., Levine, J.P. and Gurtner, G.C. 2004. Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nat. Med., 10:858-64.
-
(2004)
Nat. Med
, vol.10
, pp. 858-864
-
-
Ceradini, D.J.1
Kulkarni, A.R.2
Callaghan, M.J.3
Tepper, O.M.4
Bastidas, N.5
Kleinman, M.E.6
Capla, J.M.7
Galiano, R.D.8
Levine, J.P.9
Gurtner, G.C.10
-
9
-
-
0027443181
-
The role of hypoxia in the maintenance of hematopoietic stem cells
-
Cipolleschi, M.G., Dello Sbarba, P. and Olivotto, M. 1993. The role of hypoxia in the maintenance of hematopoietic stem cells. Blood, 82:2031-7.
-
(1993)
Blood
, vol.82
, pp. 2031-2037
-
-
Cipolleschi, M.G.1
Dello Sbarba, P.2
Olivotto, M.3
-
10
-
-
0035983324
-
Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice
-
Compernolle, V., Brusselmans, K., Acker, T., Hoet, P., Tjwa, M., Beck, H., Plaisance, S., Dor, Y., Keshet, E., Lupu, F. et al. 2002. Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice. Nat. Med., 8:702-10.
-
(2002)
Nat. Med
, vol.8
, pp. 702-710
-
-
Compernolle, V.1
Brusselmans, K.2
Acker, T.3
Hoet, P.4
Tjwa, M.5
Beck, H.6
Plaisance, S.7
Dor, Y.8
Keshet, E.9
Lupu, F.10
-
11
-
-
0032506010
-
Dissociation between bone resorption and bone formation in osteopenic transgenic mice
-
Corral, D.A., Amling, M., Priemel, M., Loyer, E., Fuchs, S., Ducy, P., Baron, R. and Karsenty, G. 1998. Dissociation between bone resorption and bone formation in osteopenic transgenic mice. Proc. Natl. Acad. Sci. U.S.A., 95:13835-40.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A
, vol.95
, pp. 13835-13840
-
-
Corral, D.A.1
Amling, M.2
Priemel, M.3
Loyer, E.4
Fuchs, S.5
Ducy, P.6
Baron, R.7
Karsenty, G.8
-
12
-
-
33644747418
-
HIF-2α regulates Oct-4: Effects of hypoxia on stem cell function, embryonic development, and tumor growth
-
Covello, K.L., Kehler, J., Yu, H., Gordan, J.D., Arsham, A.M., Hu, C.J., Labosky, P.A., Simon, M.C. and Keith, B. 2006. HIF-2α regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth. Genes. Dev., 20:557-70.
-
(2006)
Genes. Dev
, vol.20
, pp. 557-570
-
-
Covello, K.L.1
Kehler, J.2
Yu, H.3
Gordan, J.D.4
Arsham, A.M.5
Hu, C.J.6
Labosky, P.A.7
Simon, M.C.8
Keith, B.9
-
13
-
-
4344645792
-
Marrow-isolated adult multilineage inducible (MIAMI) cells, a unique population of postnatal young and old human cells with extensive expansion and differentiation potential
-
D'Ippolito, G., Diabira, S., Howard, G.A., Menei, P., Roos, B.A. and Schiller, P.C. 2004. Marrow-isolated adult multilineage inducible (MIAMI) cells, a unique population of postnatal young and old human cells with extensive expansion and differentiation potential. J. Cell. Sci., 117:2971-81.
-
(2004)
J. Cell. Sci
, vol.117
, pp. 2971-2981
-
-
D'Ippolito, G.1
Diabira, S.2
Howard, G.A.3
Menei, P.4
Roos, B.A.5
Schiller, P.C.6
-
14
-
-
33646016858
-
Low oxygen tension inhibits osteogenic differentiation and enhances stemness of human MIAMI cells
-
D'Ippolito, G., Diabira, S., Howard, G.A., Roos, B.A. and Schiller, P.C. 2006, Low oxygen tension inhibits osteogenic differentiation and enhances stemness of human MIAMI cells. Bone, 39:513-22.
-
(2006)
Bone
, vol.39
, pp. 513-522
-
-
D'Ippolito, G.1
Diabira, S.2
Howard, G.A.3
Roos, B.A.4
Schiller, P.C.5
-
15
-
-
85047692887
-
Expansion of human SCID-repopulating cells under hypoxic conditions
-
Danet, G.H., Pan, Y., Luongo, J.L., Bonnet, D.A. and Simon, M.C. 2003. Expansion of human SCID-repopulating cells under hypoxic conditions. J. Clin. Invest., 112:126-35.
-
(2003)
J. Clin. Invest
, vol.112
, pp. 126-135
-
-
Danet, G.H.1
Pan, Y.2
Luongo, J.L.3
Bonnet, D.A.4
Simon, M.C.5
-
16
-
-
0031000736
-
A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1α regulates the VEGF expression and is potentially involved in lung and vascular development
-
Ema, M., Taya, S., Yokotani, N., Sogawa, K., Matsuda, Y. and Fujii-Kuriyama, Y. 1997. A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1α regulates the VEGF expression and is potentially involved in lung and vascular development. Proc. Natl. Acad. Sci. U.S.A., 94:4273-8.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A
, vol.94
, pp. 4273-4278
-
-
Ema, M.1
Taya, S.2
Yokotani, N.3
Sogawa, K.4
Matsuda, Y.5
Fujii-Kuriyama, Y.6
-
17
-
-
25844440767
-
The rise of oxygen over the past 205 million years and the evolution of large placental mammals
-
Falkowski, P.G., Katz, M.E., Milligan, A.J., Fennel, K., Cramer, B.S., Aubry, M.P., Berner, R.A., Novacek, M.J. and Zapol, W.M. 2005. The rise of oxygen over the past 205 million years and the evolution of large placental mammals. Science, 309:2202-4.
-
(2005)
Science
, vol.309
, pp. 2202-2204
-
-
Falkowski, P.G.1
Katz, M.E.2
Milligan, A.J.3
Fennel, K.4
Cramer, B.S.5
Aubry, M.P.6
Berner, R.A.7
Novacek, M.J.8
Zapol, W.M.9
-
18
-
-
0030879909
-
Regulation of human placental development by oxygen tension
-
Genbacev, O., Zhou, Y., Ludlow, J.W. and Fisher, S.J. 1997. Regulation of human placental development by oxygen tension. Science, 277:1669-72
-
(1997)
Science
, vol.277
, pp. 1669-1672
-
-
Genbacev, O.1
Zhou, Y.2
Ludlow, J.W.3
Fisher, S.J.4
-
19
-
-
34249113091
-
Hypoxia enhances proliferation and tissue formation of human mesenchymal stem cells
-
Grayson, W.L., Zhao, F., Bunnell, B. and Ma, T. 2007. Hypoxia enhances proliferation and tissue formation of human mesenchymal stem cells. Biochem. Biophys. Res. Commun., 358:948-53.
-
(2007)
Biochem. Biophys. Res. Commun
, vol.358
, pp. 948-953
-
-
Grayson, W.L.1
Zhao, F.2
Bunnell, B.3
Ma, T.4
-
20
-
-
31744442047
-
Effects of hypoxia on human mesenchymal stem cell expansion and plasticity in 3D constructs
-
Grayson, W.L., Zhao, F., Izadpanah, R., Bunnell, B. and Ma, T. 2006. Effects of hypoxia on human mesenchymal stem cell expansion and plasticity in 3D constructs. J. Cell. Physiol., 207:331-9.
-
(2006)
J. Cell. Physiol
, vol.207
, pp. 331-339
-
-
Grayson, W.L.1
Zhao, F.2
Izadpanah, R.3
Bunnell, B.4
Ma, T.5
-
21
-
-
27644561755
-
Hypoxia requires notch signaling to maintain the undifferentiated cell state
-
Gustafsson, M.V., Zheng, X., Pereira, T., Gradin, K., Jin, S., Lundkvist, J., Ruas, J.L., Poellinger, L., Lendahl, U. and Bondesson, M. 2005. Hypoxia requires notch signaling to maintain the undifferentiated cell state. Dev. Cell., 9:617-28.
-
(2005)
Dev. Cell
, vol.9
, pp. 617-628
-
-
Gustafsson, M.V.1
Zheng, X.2
Pereira, T.3
Gradin, K.4
Jin, S.5
Lundkvist, J.6
Ruas, J.L.7
Poellinger, L.8
Lendahl, U.9
Bondesson, M.10
-
22
-
-
0026445208
-
Megascopic eukaryotic algae from the 2.1-billion-year-old negaunee iron-formation, Michigan
-
Han, T.M. and Runnegar, B. 1992. Megascopic eukaryotic algae from the 2.1-billion-year-old negaunee iron-formation, Michigan. Science, 257:232-5.
-
(1992)
Science
, vol.257
, pp. 232-235
-
-
Han, T.M.1
Runnegar, B.2
-
23
-
-
0036359548
-
Hypoxia - a key regulatory factor in tumour growth
-
Harris, A.L. 2002. Hypoxia - a key regulatory factor in tumour growth. Nat. Rev. Cancer, 2:38-47.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
24
-
-
34447616779
-
Oxygen saturation in the bone marrow of healthy volunteers
-
Harrison, J.S., Rameshwar, P., Chang, V. and Bandari, P. 2002. Oxygen saturation in the bone marrow of healthy volunteers. Blood, 99:394.
-
(2002)
Blood
, vol.99
, pp. 394
-
-
Harrison, J.S.1
Rameshwar, P.2
Chang, V.3
Bandari, P.4
-
25
-
-
0035917313
-
2 sensing
-
2 sensing. Science, 292:464-8.
-
(2001)
Science
, vol.292
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
Kim, W.4
Valiando, J.5
Ohh, M.6
Salic, A.7
Asara, J.M.8
Lane, W.S.9
Kaelin Jr., W.G.10
-
26
-
-
0034011611
-
Incubation of murine bone marrow cells in hypoxia ensures the maintenance of marrow-repopulating ability together with the expansion of committed progenitors
-
Ivanovic, Z., Bartolozzi, B., Bernabei, P.A., Cipolleschi, M.G., Rovida, E., Milenkovic, P., Praloran, V. and Dello Sbarba, P. 2000. Incubation of murine bone marrow cells in hypoxia ensures the maintenance of marrow-repopulating ability together with the expansion of committed progenitors. Br. J. Haematol., 108:424-9.
-
(2000)
Br. J. Haematol
, vol.108
, pp. 424-429
-
-
Ivanovic, Z.1
Bartolozzi, B.2
Bernabei, P.A.3
Cipolleschi, M.G.4
Rovida, E.5
Milenkovic, P.6
Praloran, V.7
Dello Sbarba, P.8
-
27
-
-
0036143605
-
Hypoxia maintains and interleukin-3 reduces the pre-colony-forming cell potential of dividing CD34(+) murine bone marrow cells
-
Ivanovic, Z., Belloc, F., Faucher, J.L., Cipolleschi, M.G., Praloran, V. and Dello Sbarba, P. 2002. Hypoxia maintains and interleukin-3 reduces the pre-colony-forming cell potential of dividing CD34(+) murine bone marrow cells. Exp. Hematol., 30:67-73.
-
(2002)
Exp. Hematol
, vol.30
, pp. 67-73
-
-
Ivanovic, Z.1
Belloc, F.2
Faucher, J.L.3
Cipolleschi, M.G.4
Praloran, V.5
Dello Sbarba, P.6
-
28
-
-
15444342958
-
2 homeostasis by hypoxia-inducible factor 1α
-
2 homeostasis by hypoxia-inducible factor 1α. Genes. Dev., 12:149-62.
-
(1998)
Genes. Dev
, vol.12
, pp. 149-162
-
-
Iyer, N.V.1
Kotch, L.E.2
Agani, F.3
Leung, S.W.4
Laughner, E.5
Wenger, R.H.6
Gassmann, M.7
Gearhart, J.D.8
Lawler, A.M.9
Yu, A.Y.10
-
29
-
-
0035917808
-
2-regulated prolyl hydroxylation
-
2-regulated prolyl hydroxylation. Science, 292:468-72.
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
Kriegsheim, A.7
Hebestreit, H.F.8
Mukherji, M.9
Schofield, C.J.10
-
30
-
-
32544438499
-
The regulation of trophoblast differentiation by oxygen in the first trimester of pregnancy
-
James, I.L., Stone, P.R. and Chamley, L.W. 2006. The regulation of trophoblast differentiation by oxygen in the first trimester of pregnancy. Human Reprod. Update, 12:137-44.
-
(2006)
Human Reprod. Update
, vol.12
, pp. 137-144
-
-
James, I.L.1
Stone, P.R.2
Chamley, L.W.3
-
31
-
-
0035062024
-
Evaluation of respiratory gases and acid-base gradients in human fetal fluids and uteroplacental tissue between 7 and 16 weeks gestation
-
Jauniaux, E., Watson, A. and Burton, G. 2001. Evaluation of respiratory gases and acid-base gradients in human fetal fluids and uteroplacental tissue between 7 and 16 weeks gestation. Am. J. Obst. Gynecol., 184:998-1003.
-
(2001)
Am. J. Obst. Gynecol
, vol.184
, pp. 998-1003
-
-
Jauniaux, E.1
Watson, A.2
Burton, G.3
-
32
-
-
21344442127
-
Hypoxia inhibits adipocyte differentiation in a HDAC-independent manner
-
Kim, K.H., Song, M.J., Chung, J., Park, H. and Kim, J.B. 2005. Hypoxia inhibits adipocyte differentiation in a HDAC-independent manner. Biochem. Biophys. Res. Commun., 333:1178-84.
-
(2005)
Biochem. Biophys. Res. Commun
, vol.333
, pp. 1178-1184
-
-
Kim, K.H.1
Song, M.J.2
Chung, J.3
Park, H.4
Kim, J.B.5
-
33
-
-
0037133250
-
Abnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1α-deficient chimeric mice
-
Kojima, H., Gu, H., Nomura, S., Caldwell, C.C., Kobata, T., Carmeliet, P., Semenza, G.L. and Sitkovsky, M.V. 2002. Abnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1α-deficient chimeric mice. Proc. Natl. Acad. Sci. U.S.A., 99:2170-4.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A
, vol.99
, pp. 2170-2174
-
-
Kojima, H.1
Gu, H.2
Nomura, S.3
Caldwell, C.C.4
Kobata, T.5
Carmeliet, P.6
Semenza, G.L.7
Sitkovsky, M.V.8
-
34
-
-
0043180527
-
HIF-1α deficiency perturbs T and B cell functions
-
Kojima, H., Sitkovsky, M.V. and Cascalho, M. 2003. HIF-1α deficiency perturbs T and B cell functions. Curr. Pharm. Des., 9:1827-32.
-
(2003)
Curr. Pharm. Des
, vol.9
, pp. 1827-1832
-
-
Kojima, H.1
Sitkovsky, M.V.2
Cascalho, M.3
-
35
-
-
17544384815
-
ARNT-deficient mice and placental differentiation
-
Kozak, K.R., Abbott, B. and Hankinson, O. 1997. ARNT-deficient mice and placental differentiation. Dev. Biol., 191:297-305.
-
(1997)
Dev. Biol
, vol.191
, pp. 297-305
-
-
Kozak, K.R.1
Abbott, B.2
Hankinson, O.3
-
36
-
-
33750038847
-
Differentiation arrest by hypoxia
-
Lin, Q., Lee, Y.J. and Yun, Z. 2006. Differentiation arrest by hypoxia. J. Biol. Chem., 281:30678-83.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 30678-30683
-
-
Lin, Q.1
Lee, Y.J.2
Yun, Z.3
-
37
-
-
33645125788
-
Effect of reduced oxygen tension on chondrogenesis and osteogenesis in adipose-derived mesenchymal cells
-
Malladi, P., Xu, Y., Chiou, M., Giaccia, A.J. and Longaker, M.T. 2006. Effect of reduced oxygen tension on chondrogenesis and osteogenesis in adipose-derived mesenchymal cells. Am. J. Physiol. Cell. Physiol., 290:C1139-1146.
-
(2006)
Am. J. Physiol. Cell. Physiol
, vol.290
-
-
Malladi, P.1
Xu, Y.2
Chiou, M.3
Giaccia, A.J.4
Longaker, M.T.5
-
38
-
-
34250857921
-
Hypoxia inducible factor-1α deficiency affects chondrogenesis of adipose-derived adult stromal cells
-
Malladi, P., Xu, Y., Chiou, M., Giaccia, A.J. and Longaker, M.T. 2007. Hypoxia inducible factor-1α deficiency affects chondrogenesis of adipose-derived adult stromal cells, Tissue Eng., 13:1159-71.
-
(2007)
Tissue Eng
, vol.13
, pp. 1159-1171
-
-
Malladi, P.1
Xu, Y.2
Chiou, M.3
Giaccia, A.J.4
Longaker, M.T.5
-
39
-
-
0014402817
-
Origin in repopulating cells after localized bone marrow depletion
-
Maloney, M.A. and Patt, H.M. 1968. Origin in repopulating cells after localized bone marrow depletion. Science. 165:71-3
-
(1968)
Science
, vol.165
, pp. 71-73
-
-
Maloney, M.A.1
Patt, H.M.2
-
40
-
-
24344502368
-
Hypoxia-inducible factor-dependent histone deacetylase activity determines stem cell fate in the placenta
-
Maltepe, E., Krampitz, G.W., Okazaki, K.M., Red-Horse, K., Mak, W., Simon, M.C. and Fisher, S.J. 2005. Hypoxia-inducible factor-dependent histone deacetylase activity determines stem cell fate in the placenta. Development, 132:3393-403.
-
(2005)
Development
, vol.132
, pp. 3393-3403
-
-
Maltepe, E.1
Krampitz, G.W.2
Okazaki, K.M.3
Red-Horse, K.4
Mak, W.5
Simon, M.C.6
Fisher, S.J.7
-
41
-
-
0030943461
-
Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT
-
Maltepe, E., Schmidt, J.V., Baunoch, D., Bradfield, C.A. and Simon, M.C. 1997. Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT. Nature, 386:403-7.
-
(1997)
Nature
, vol.386
, pp. 403-407
-
-
Maltepe, E.1
Schmidt, J.V.2
Baunoch, D.3
Bradfield, C.A.4
Simon, M.C.5
-
42
-
-
34147144960
-
Transcriptional profiling of human cord blood CD133+ and cultured bone marrow mesenchymal stem cells in response to hypoxia
-
Martin-Rendon, E., Hale, S.J., Ryan, D., Baban, D., Forde, S.P., Roubelakis, M., Sweeney, D., Moukayed, M., Harris, A.L., Davies, K. et al. 2007. Transcriptional profiling of human cord blood CD133+ and cultured bone marrow mesenchymal stem cells in response to hypoxia. Stem Cells, 25:1003-12.
-
(2007)
Stem Cells
, vol.25
, pp. 1003-1012
-
-
Martin-Rendon, E.1
Hale, S.J.2
Ryan, D.3
Baban, D.4
Forde, S.P.5
Roubelakis, M.6
Sweeney, D.7
Moukayed, M.8
Harris, A.L.9
Davies, K.10
-
43
-
-
0141518586
-
Primitive, and protective, our cellular oxygenation status?
-
Massabuau, J.C. 2003. Primitive, and protective, our cellular oxygenation status? Mech. Ageing Dev., 124:857-63.
-
(2003)
Mech. Ageing Dev
, vol.124
, pp. 857-863
-
-
Massabuau, J.C.1
-
44
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
Maxwell, P.H., Wiesener, M.S., Chang, G.W., Clifford, S.C., Vaux, E.C., Cockman, M.E., Wykoff, C.C., Pugh, C.W., Maher, E.R. and Ratcliffe, P.J. 1999. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature, 399:271-5.
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
Clifford, S.C.4
Vaux, E.C.5
Cockman, M.E.6
Wykoff, C.C.7
Pugh, C.W.8
Maher, E.R.9
Ratcliffe, P.J.10
-
45
-
-
0037033095
-
Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes
-
Miyazaki, K., Kawamoto, T., Tanimoto, K., Nishiyama, M., Honda, H. and Kato, Y. 2002. Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes. J. Biol. Chem., 277:47014-21.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 47014-47021
-
-
Miyazaki, K.1
Kawamoto, T.2
Tanimoto, K.3
Nishiyama, M.4
Honda, H.5
Kato, Y.6
-
46
-
-
33644845081
-
Microenvironmental niches in the bone marrow required for B-cell development
-
Nagasawa, T. 2006. Microenvironmental niches in the bone marrow required for B-cell development. Nat. Rev. Immunol., 6:107-16.
-
(2006)
Nat. Rev. Immunol
, vol.6
, pp. 107-116
-
-
Nagasawa, T.1
-
47
-
-
0033776536
-
Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel-Lindau protein
-
Ohh, M., Park, C.W., Ivan, M., Hoffman, M.A., Kim, T.Y., Huang, L.E., Pavletich, N., Chau, V. and Kaelin, W.G. 2000. Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel-Lindau protein. Nat. Cell. Biol., 2:423-7.
-
(2000)
Nat. Cell. Biol
, vol.2
, pp. 423-427
-
-
Ohh, M.1
Park, C.W.2
Ivan, M.3
Hoffman, M.A.4
Kim, T.Y.5
Huang, L.E.6
Pavletich, N.7
Chau, V.8
Kaelin, W.G.9
-
48
-
-
33744959141
-
Expression of vascular endothelial growth factor receptor I in bone marrow-derived mesenchymal cells is dependent on hypoxia-inducible factor 1
-
Okuyama, H., Krishnamachary, B., Zhou, Y.F., Nagasawa, H., Bosch-Marce, M. and Semenza, G.L. 2006. Expression of vascular endothelial growth factor receptor I in bone marrow-derived mesenchymal cells is dependent on hypoxia-inducible factor 1. J. Biol. Chem., 281:15554-63.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 15554-15563
-
-
Okuyama, H.1
Krishnamachary, B.2
Zhou, Y.F.3
Nagasawa, H.4
Bosch-Marce, M.5
Semenza, G.L.6
-
49
-
-
33847050240
-
Non-heme dioxygenases: Cellular sensors and regulators jelly rolled into one?
-
Ozer, A. and Bruick, R.K. 2007. Non-heme dioxygenases: cellular sensors and regulators jelly rolled into one? Nat. Chem. Biol., 3:144-53.
-
(2007)
Nat. Chem. Biol
, vol.3
, pp. 144-153
-
-
Ozer, A.1
Bruick, R.K.2
-
50
-
-
34248359065
-
Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia
-
Parmar, K., Mauch, P., Vergilio, J.A., Sackstein, R. and Down, J.D. 2007. Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia. Proc. Natl. Acad. Sci. U.S.A.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A
-
-
Parmar, K.1
Mauch, P.2
Vergilio, J.A.3
Sackstein, R.4
Down, J.D.5
-
51
-
-
0034682513
-
The transcription factor EPAS-1/hypoxia-inducible factor 2α plays an important role in vascular remodeling
-
Peng, J., Zhang, L., Drysdale, L. and Fong, G.H. 2000. The transcription factor EPAS-1/hypoxia-inducible factor 2α plays an important role in vascular remodeling. Proc. Natl. Acad. Sci. U.S.A., 97:8386-91.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A
, vol.97
, pp. 8386-8391
-
-
Peng, J.1
Zhang, L.2
Drysdale, L.3
Fong, G.H.4
-
52
-
-
34248222569
-
Hif-1α regulates differentiation of limb bud mesenchyme and joint development
-
Provot, S., Zinyk, D., Gunes, Y., Kathri, R., Le, Q., Kronenberg, H.M., Johnson, R.S., Longaker, M.T., Giaccia, A.J. and Schipani, E. 2007. Hif-1α regulates differentiation of limb bud mesenchyme and joint development. J Cell. Biol., 177:451-64.
-
(2007)
J Cell. Biol
, vol.177
, pp. 451-464
-
-
Provot, S.1
Zinyk, D.2
Gunes, Y.3
Kathri, R.4
Le, Q.5
Kronenberg, H.M.6
Johnson, R.S.7
Longaker, M.T.8
Giaccia, A.J.9
Schipani, E.10
-
53
-
-
0033873636
-
Expression, ontogeny, and regulation of hypoxia-inducible transcription factors in the human placenta
-
Rajakumar, A. and Conrad, K.P. 2000. Expression, ontogeny, and regulation of hypoxia-inducible transcription factors in the human placenta. Biology Reprod., 63:559-69.
-
(2000)
Biology Reprod
, vol.63
, pp. 559-569
-
-
Rajakumar, A.1
Conrad, K.P.2
-
54
-
-
23844493183
-
Hypoxia induces chondrocyte-specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9
-
Robins, J.C., Akeno, N., Mukherjee, A., Dalal, R.R., Aronow, B.J., Koopman, P. and Clemens, T.L. 2005. Hypoxia induces chondrocyte-specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9. Bone, 37:313-22.
-
(2005)
Bone
, vol.37
, pp. 313-322
-
-
Robins, J.C.1
Akeno, N.2
Mukherjee, A.3
Dalal, R.R.4
Aronow, B.J.5
Koopman, P.6
Clemens, T.L.7
-
55
-
-
0026782588
-
Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy
-
Rodesch, F., Simon, P., Donner, C. and Jauniaux, E. 1992. Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy. Obstet. Gynecol., 80:283-5.
-
(1992)
Obstet. Gynecol
, vol.80
, pp. 283-285
-
-
Rodesch, F.1
Simon, P.2
Donner, C.3
Jauniaux, E.4
-
56
-
-
0017599669
-
Bone marrow regeneration from cortex following segmental fractioned irradiation
-
Rubin, P., Elbadawi, N.A., Thomson, R.A. and Cooper, R.A. 1977. Bone marrow regeneration from cortex following segmental fractioned irradiation. Int. J. Radiat. Oncol. Biol. Phys., 2:27-38.
-
(1977)
Int. J. Radiat. Oncol. Biol. Phys
, vol.2
, pp. 27-38
-
-
Rubin, P.1
Elbadawi, N.A.2
Thomson, R.A.3
Cooper, R.A.4
-
57
-
-
0032100732
-
HIF-1α is required for solid tumor formation and embryonic vascularizition
-
Ryan, H.E.,Lo,J. and Johnson, R.S. 1998. HIF-1α is required for solid tumor formation and embryonic vascularizition. EMBO J., 17:3005-15.
-
(1998)
EMBO J
, vol.17
, pp. 3005-3015
-
-
Ryan, H.E.1
Lo, J.2
Johnson, R.S.3
-
58
-
-
0028225356
-
Chronic hypoxia impairs the differentiation of 3T3-L1 fibroblast in culture: Role of sustained limtein kinase C activation
-
Sahai, A., Patel, M.S., Zavosh, A.S. and Tannen, R.L. 1994. Chronic hypoxia impairs the differentiation of 3T3-L1 fibroblast in culture: role of sustained limtein kinase C activation. J. Cell. Physiol., 160:107-12.
-
(1994)
J. Cell. Physiol
, vol.160
, pp. 107-112
-
-
Sahai, A.1
Patel, M.S.2
Zavosh, A.S.3
Tannen, R.L.4
-
59
-
-
0035499204
-
Hypoxia in cartilage: HIF-1α is essential for chondrocyte growth arrest and survival
-
Schipani, E., Ryan, H.E., Didrickson, S., Kobayashi, T., Knight, M. and Johnson, R.S. 2001. Hypoxia in cartilage: HIF-1α is essential for chondrocyte growth arrest and survival. Genes Dev., 15:2865-76.
-
(2001)
Genes Dev
, vol.15
, pp. 2865-2876
-
-
Schipani, E.1
Ryan, H.E.2
Didrickson, S.3
Kobayashi, T.4
Knight, M.5
Johnson, R.S.6
-
60
-
-
0041440036
-
The HIF family member EPAS1/HIF-2α is required for normal hematopoiesis in mice
-
Scortegagna, M., Morris, M.A., Oktay, Y., Bennett, M. and Garcia, J.A. 2003. The HIF family member EPAS1/HIF-2α is required for normal hematopoiesis in mice. Blood, 102:1634-40.
-
(2003)
Blood
, vol.102
, pp. 1634-1640
-
-
Scortegagna, M.1
Morris, M.A.2
Oktay, Y.3
Bennett, M.4
Garcia, J.A.5
-
61
-
-
0034006016
-
HIF- 1: Mediator of physiological and pathophysiological responses to hypoxia
-
Semenza, G.L. 2000. HIF- 1: mediator of physiological and pathophysiological responses to hypoxia. J. Appl. Physiol., 88:1474-80.
-
(2000)
J. Appl. Physiol
, vol.88
, pp. 1474-1480
-
-
Semenza, G.L.1
-
62
-
-
0142166332
-
Targeting HIF-1 for can can therapy
-
Semenza, G.L. 2003. Targeting HIF-1 for can can therapy. Nat. Rev. Cancer, 3:721-32.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
63
-
-
4644368368
-
EPAS1 promotes adipose differentiation in 3T3-L1 cells
-
Shimba, S., Wada, T., Hara, S. and Tezuka, M. 2004. EPAS1 promotes adipose differentiation in 3T3-L1 cells. J Biol. Chem., 279:40946-53.
-
(2004)
J Biol. Chem
, vol.279
, pp. 40946-40953
-
-
Shimba, S.1
Wada, T.2
Hara, S.3
Tezuka, M.4
-
64
-
-
0027245963
-
Pref-1, a protein. containing EGF-like repeats, inhibits adipocyte differentiation
-
Smas, C.M. and Sul, H.S. 1993. Pref-1, a protein. containing EGF-like repeats, inhibits adipocyte differentiation. Cell., 73:725-34.
-
(1993)
Cell
, vol.73
, pp. 725-734
-
-
Smas, C.M.1
Sul, H.S.2
-
65
-
-
0032213236
-
The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development
-
Tian, H., Hammer, R.E., Matsumoto, A.M., Russell, D.W. and McKnight, S.L. 1998. The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development. Genes. Dev., 12:3320-4.
-
(1998)
Genes. Dev
, vol.12
, pp. 3320-3324
-
-
Tian, H.1
Hammer, R.E.2
Matsumoto, A.M.3
Russell, D.W.4
McKnight, S.L.5
-
66
-
-
33744926266
-
Quantitative proteomics reveals posttranslational control as a regulatory factor in primary hematopoietic stem cells
-
Unwin, R.D., Smith, D.L., Blinco, D., Wilson, C.L.,Miller, C.J., Evans, C.A., Jaworska, E., Baldwin, S.A., Barnes, K., Pierce, A. et al. 2006. Quantitative proteomics reveals posttranslational control as a regulatory factor in primary hematopoietic stem cells. Blood, 107:4687-94.
-
(2006)
Blood
, vol.107
, pp. 4687-4694
-
-
Unwin, R.D.1
Smith, D.L.2
Blinco, D.3
Wilson, C.L.4
Miller, C.J.5
Evans, C.A.6
Jaworska, E.7
Baldwin, S.A.8
Barnes, K.9
Pierce, A.10
-
67
-
-
0025913227
-
Oxygen in mammalian tissue: Methods of measurement and affinities of various reactions
-
Vanderkooi, J.M., Erecinska, M. and Silver, I.A. 1991. Oxygen in mammalian tissue: methods of measurement and affinities of various reactions. Am. J. Physiol., 260:C1131-50.
-
(1991)
Am. J. Physiol
, vol.260
-
-
Vanderkooi, J.M.1
Erecinska, M.2
Silver, I.A.3
-
69
-
-
1942457308
-
Hematopoiesis is severely altered in mice with an induced osteoblast deficiency
-
Visnjic, D., Kalajzic, Z., Rowe, D.W., Katavic, V., Lorenzo, J. and Aguila, H.L. 2004. Hematopoiesis is severely altered in mice with an induced osteoblast deficiency. Blood, 103:3258-64.
-
(2004)
Blood
, vol.103
, pp. 3258-3264
-
-
Visnjic, D.1
Kalajzic, Z.2
Rowe, D.W.3
Katavic, V.4
Lorenzo, J.5
Aguila, H.L.6
-
71
-
-
33845322632
-
Pref-1, a preadipocyte secreted factor that inhibits adipogenesis
-
Wang, Y., Kim, K.A., Kim, J.H. and Sul, H.S. 2006. Pref-1, a preadipocyte secreted factor that inhibits adipogenesis. J. Nutr., 136:2953-6.
-
(2006)
J. Nutr
, vol.136
, pp. 2953-2956
-
-
Wang, Y.1
Kim, K.A.2
Kim, J.H.3
Sul, H.S.4
-
72
-
-
0037315337
-
Widespread hypoxia-inducible expression of HIF-2α in distinct cell populations of different organs
-
Wiesener, M.S., Jurgensen, J.S., Rosenberger, C., Scholze, C.K., Horstrup, J.H., Warnecke, C., Mandriota, S., Bechmann, I., Frei, U.A, Pugh, C.W. et al. 2003. Widespread hypoxia-inducible expression of HIF-2α in distinct cell populations of different organs. FASEB. J., 17:271-3.
-
(2003)
FASEB. J
, vol.17
, pp. 271-273
-
-
Wiesener, M.S.1
Jurgensen, J.S.2
Rosenberger, C.3
Scholze, C.K.4
Horstrup, J.H.5
Warnecke, C.6
Mandriota, S.7
Bechmann, I.8
Frei, U.A.9
Pugh, C.W.10
-
73
-
-
33644827383
-
Bone-marrow haermatopoietic-stem-cell niches
-
Wilson, A. and Trumpp, A. 2006. Bone-marrow haermatopoietic-stem-cell niches. Nat. Rev. Immunol., 6:93-106.
-
(2006)
Nat. Rev. Immunol
, vol.6
, pp. 93-106
-
-
Wilson, A.1
Trumpp, A.2
-
74
-
-
0034649507
-
Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling
-
Wykoff, C.C., Pugh, C.W., Maxwell, P.H., Harris, A.L., and Ratcliffe, P.J. 2000. Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling. Oncogene, 19:6297-305.
-
(2000)
Oncogene
, vol.19
, pp. 6297-6305
-
-
Wykoff, C.C.1
Pugh, C.W.2
Maxwell, P.H.3
Harris, A.L.4
Ratcliffe, P.J.5
-
75
-
-
33646435309
-
The stem cell niches in bone
-
Yin, T. and Li, L. 2006. The stem cell niches in bone. J. Clin. Invest., 116:1195-201.
-
(2006)
J. Clin. Invest
, vol.116
, pp. 1195-1201
-
-
Yin, T.1
Li, L.2
-
76
-
-
16244406228
-
Adaptive myogenesis underhypoxia
-
Yun, Z., Lin, Q. and Giaccia, A.J. 2005. Adaptive myogenesis underhypoxia. Mol. Cell. Biol., 25:3040-55.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 3040-3055
-
-
Yun, Z.1
Lin, Q.2
Giaccia, A.J.3
-
77
-
-
0036198010
-
Inhibition of PPARγ2 gene expression by the HIF-1-regulated gene DEC1/Stra13: A mechanism for regulation of adipogenesis by hypoxia
-
Yun, Z., Maecker, H.L., Johnson, R.S. and Giaccia, A.J. 2002. Inhibition of PPARγ2 gene expression by the HIF-1-regulated gene DEC1/Stra13: a mechanism for regulation of adipogenesis by hypoxia. Dev. Cell., 2:331-41.
-
(2002)
Dev. Cell
, vol.2
, pp. 331-341
-
-
Yun, Z.1
Maecker, H.L.2
Johnson, R.S.3
Giaccia, A.J.4
-
78
-
-
20744449945
-
Hypoxia inhibition of adipocytogenesis in human bone marrow stromal cells requires transforming growth factor-beta/Smad3 signaling
-
Zhou, S., Lechpammer, S., Greenberger, J.S. and Glowacki, J. 2005. Hypoxia inhibition of adipocytogenesis in human bone marrow stromal cells requires transforming growth factor-beta/Smad3 signaling. J Biol. Chem., 280:22688-96.
-
(2005)
J Biol. Chem
, vol.280
, pp. 22688-22696
-
-
Zhou, S.1
Lechpammer, S.2
Greenberger, J.S.3
Glowacki, J.4
|