Studies on the condensation of depolymerized chitosans with DNA for preparing chitosan-DNA nanoparticles for gene delivery applications

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 89, Issue 2, 2009, Pages 282-292

  Morris, Viola B ^a,b   Neethu, S ^a   Abraham, T E ^a   Pillai, C K S ^a,b   Sharma, Chandra P ^b  

^a NATIONAL CHEMICAL LABORATORY   (India)

^b SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES AND TECHNOLOGY   (India)

Author keywords

Chitosan; Depolymerization; DNA; Gene therapy delivery; Nanomaterial; Polymer

Indexed keywords

AFM; BIOLOGICAL STUDIES; CHARGE RATIO; DEGREE OF DEACETYLATION; FTIR; GENE DELIVERY; GENE TRANSFECTION; HELA CELL; HIGH MOLECULAR WEIGHT; LOW MOLECULAR WEIGHT; NANO-SIZED; NANOMATERIAL; OXIDATIVE DEGRADATION; PEGFP PLASMID; POLYPLEXES; ROOM TEMPERATURE; SEM; STRONG BINDING; UNIFORM-SIZED; UV SPECTROSCOPY;

BINDING ENERGY; BIOLOGICAL MEMBRANES; CHITIN; CHITOSAN; CONDENSATION; DERIVATIVES; DNA; FOURIER TRANSFORM INFRARED SPECTROSCOPY; GENE TRANSFER; GENES; HYDROGELS; MULTILAYERS; NANOPARTICLES; NANOSTRUCTURED MATERIALS; NUCLEIC ACIDS; ULTRAVIOLET SPECTROSCOPY; WEIGHING;

MOLECULAR WEIGHT;

CHITOSAN DERIVATIVE; ENHANCED GREEN FLUORESCENT PROTEIN; NANOPARTICLE; PLASMID DNA; SODIUM NITRATE;

ARTICLE; ATOMIC FORCE MICROSCOPY; BINDING AFFINITY; CHEMICAL STRUCTURE; CIRCULAR DICHROISM; COMPLEX FORMATION; CONTROLLED STUDY; DEACETYLATION; DEPOLYMERIZATION; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; MOLECULAR WEIGHT; OXIDATION; PH MEASUREMENT; POLYMERIZATION; ROOM TEMPERATURE; SCANNING ELECTRON MICROSCOPY; ULTRAVIOLET SPECTROSCOPY; VISCOSITY;

ANIMALS; CARBOHYDRATE CONFORMATION; CARBOHYDRATE SEQUENCE; CATTLE; CHITOSAN; DNA; DRUG CARRIERS; GENE THERAPY; GENE TRANSFER TECHNIQUES; HELA CELLS; HUMANS; MACROMOLECULAR SUBSTANCES; MATERIALS TESTING; MICROSCOPY, ATOMIC FORCE; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; NANOPARTICLES; PARTICLE SIZE; VISCOSITY;

EID: 65949084232     PISSN: 15524973     EISSN: 15524981     Source Type: Journal    
DOI: 10.1002/jbm.b.31214     Document Type: Article

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