-
1
-
-
0021887991
-
Immunochemical and biochemical characterization of a glioma-associated extracellular matrix glycoprotein
-
doi: 10.1002/jcb.240280302
-
Bourdon MA, Matthews TJ, Pizzo SV, Bigner DD (1985) Immunochemical and biochemical characterization of a glioma-associated extracellular matrix glycoprotein. J Cell Biochem 28:183-195. doi: 10.1002/jcb.240280302
-
(1985)
J Cell Biochem
, vol.28
, pp. 183-195
-
-
Bourdon, M.A.1
Matthews, T.J.2
Pizzo, S.V.3
Bigner, D.D.4
-
2
-
-
0020527983
-
Human glioma-mesenchymal extracellular matrix antigen defined by monoclonal antibody
-
Bourdon MA, Wikstrand CJ, Furthmayr H, Matthews TJ, Bigner DD (1983) Human glioma-mesenchymal extracellular matrix antigen defined by monoclonal antibody. Cancer Res 43:2796-2805
-
(1983)
Cancer Res
, vol.43
, pp. 2796-2805
-
-
Bourdon, M.A.1
Wikstrand, C.J.2
Furthmayr, H.3
Matthews, T.J.4
Bigner, D.D.5
-
3
-
-
0029031343
-
Phase I studies of treatment of malignant gliomas and neoplastic meningitis with 131I-radiolabeled monoclonal antibodies anti-tenascin 81C6 and anti-chondroitin proteoglycan sulfate Me1-14 F (ab')2-a preliminary report
-
doi: 10.1007/BF01052668
-
Bigner DD, Brown M, Coleman RE, Friedman AH, Friedman HS, McLendon RE, Bigner SH, Zhao XG, Wikstrand CJ, Pegram CN et al (1995) Phase I studies of treatment of malignant gliomas and neoplastic meningitis with 131I-radiolabeled monoclonal antibodies anti-tenascin 81C6 and anti-chondroitin proteoglycan sulfate Me1-14 F (ab')2-a preliminary report. J Neurooncol 24:109-122. doi: 10.1007/BF01052668
-
(1995)
J Neurooncol
, vol.24
, pp. 109-122
-
-
Bigner, D.D.1
Brown, M.2
Coleman, R.E.3
Friedman, A.H.4
Friedman, H.S.5
McLendon, R.E.6
Bigner, S.H.7
Zhao, X.G.8
Wikstrand, C.J.9
Pegram, C.N.10
-
4
-
-
0034669697
-
Phase I trial results of iodine-131-labeled antitenascin monoclonal antibody 81C6 treatment of patients with newly diagnosed malignant gliomas
-
Cokgor I, Akabani G, Kuan CT, Friedman HS, Friedman AH, Coleman RE, McLendon RE, Bigner SH, Zhao XG, Garcia-Turner AM, Pegram CN, Wikstrand CJ, Shafman TD, Herndon JEII, Provenzale JM, Zalutsky MR, Bigner DD (2000) Phase I trial results of iodine-131-labeled antitenascin monoclonal antibody 81C6 treatment of patients with newly diagnosed malignant gliomas. J Clin Oncol 18:3862-3872
-
(2000)
J Clin Oncol
, vol.18
, pp. 3862-3872
-
-
Cokgor, I.1
Akabani, G.2
Kuan, C.T.3
Friedman, H.S.4
Friedman, A.H.5
Coleman, R.E.6
McLendon, R.E.7
Bigner, S.H.8
Zhao, X.G.9
Garcia-Turner, A.M.10
Pegram, C.N.11
Wikstrand, C.J.12
Shafman, T.D.13
Herndon, J.E.I.I.14
Provenzale, J.M.15
Zalutsky, M.R.16
Bigner, D.D.17
-
5
-
-
0023773244
-
The localisation of radiolabelled murine monoclonal antibody 81C6 and its Fab fragment in human glioma xenografts in athymic mice
-
doi: 10.3109/02688698808992668
-
Colapinto EV, Lee YS, Humphrey PA, Zalutsky MR, Friedman HS, Bullard DE, Bigner DD (1988) The localisation of radiolabelled murine monoclonal antibody 81C6 and its Fab fragment in human glioma xenografts in athymic mice. Br J Neurosurg 2:179-191. doi: 10.3109/02688698808992668
-
(1988)
Br J Neurosurg
, vol.2
, pp. 179-191
-
-
Colapinto, E.V.1
Lee, Y.S.2
Humphrey, P.A.3
Zalutsky, M.R.4
Friedman, H.S.5
Bullard, D.E.6
Bigner, D.D.7
-
6
-
-
0023892266
-
Treatment of intracranial human glioma xenografts with 131I-labeled anti-tenascin monoclonal antibody 81C6
-
Lee Y, Bullard DE, Humphrey PA, Colapinto EV, Friedman HS, Zalutsky MR, Coleman RE, Bigner DD (1988) Treatment of intracranial human glioma xenografts with 131I-labeled anti-tenascin monoclonal antibody 81C6. Cancer Res 48:2904-2910
-
(1988)
Cancer Res
, vol.48
, pp. 2904-2910
-
-
Lee, Y.1
Bullard, D.E.2
Humphrey, P.A.3
Colapinto, E.V.4
Friedman, H.S.5
Zalutsky, M.R.6
Coleman, R.E.7
Bigner, D.D.8
-
7
-
-
34248176832
-
Tumor resection cavity administered iodine-131-labeled antitenascin 81C6 radioimmunotherapy in patients with malignant glioma: Neuropathology aspects
-
doi: 10.1016/j.nucmedbio.2007.01.009
-
McLendon RE, Akabani G, Friedman HS, Reardon DA, Cleveland L, Cokgor I, Herndon JEII, Wikstrand C, Boulton ST, Friedman AH, Bigner DD, Zalutsky MR (2007) Tumor resection cavity administered iodine-131-labeled antitenascin 81C6 radioimmunotherapy in patients with malignant glioma: neuropathology aspects. Nucl Med Biol 34:405-413. doi: 10.1016/ j.nucmedbio.2007.01.009
-
(2007)
Nucl Med Biol
, vol.34
, pp. 405-413
-
-
McLendon, R.E.1
Akabani, G.2
Friedman, H.S.3
Reardon, D.A.4
Cleveland, L.5
Cokgor, I.6
Herndon, J.E.I.I.7
Wikstrand, C.8
Boulton, S.T.9
Friedman, A.H.10
Bigner, D.D.11
Zalutsky, M.R.12
-
8
-
-
0036498790
-
Phase II trial of murine (131)I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas
-
doi: 10.1200/JCO.20.5.1389
-
Reardon DA, Akabani G, Coleman RE, Friedman AH, Friedman HS, Herndon JEII, Cokgor I, McLendon RE, Pegram CN, Provenzale JM, Quinn JA, Rich JN, Regalado LV, Sampson JH, Shafman TD, Wikstrand CJ, Wong TZ, Zhao XG, Zalutsky MR, Bigner DD (2002) Phase II trial of murine (131)I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas. J Clin Oncol 20:1389-1397. doi: 10.1200/JCO.20.5.1389
-
(2002)
J Clin Oncol
, vol.20
, pp. 1389-1397
-
-
Reardon, D.A.1
Akabani, G.2
Coleman, R.E.3
Friedman, A.H.4
Friedman, H.S.5
Herndon, J.E.I.I.6
Cokgor, I.7
McLendon, R.E.8
Pegram, C.N.9
Provenzale, J.M.10
Quinn, J.A.11
Rich, J.N.12
Regalado, L.V.13
Sampson, J.H.14
Shafman, T.D.15
Wikstrand, C.J.16
Wong, T.Z.17
Zhao, X.G.18
Zalutsky, M.R.19
Bigner, D.D.20
more..
-
9
-
-
3242798990
-
Phase 1 trial study of 131I-labeled chimeric 81C6 monoclonal antibody for the treatment of patients with non-Hodgkin lymphoma
-
doi: 10.1182/blood-2003-12-4264
-
Rizzieri DA, Akabani G, Zalutsky MR, Coleman RE, Metzler SD, Bowsher JE, Toaso B, Anderson E, Lagoo A, Clayton S, Pegram CN, Moore JO, Gockerman JP, DeCastro C, Gasparetto C, Chao NJ, Bigner DD (2004) Phase 1 trial study of 131I-labeled chimeric 81C6 monoclonal antibody for the treatment of patients with non-Hodgkin lymphoma. Blood 104:642-648. doi: 10.1182/blood-2003-12-4264
-
(2004)
Blood
, vol.104
, pp. 642-648
-
-
Rizzieri, D.A.1
Akabani, G.2
Zalutsky, M.R.3
Coleman, R.E.4
Metzler, S.D.5
Bowsher, J.E.6
Toaso, B.7
Anderson, E.8
Lagoo, A.9
Clayton, S.10
Pegram, C.N.11
Moore, J.O.12
Gockerman, J.P.13
DeCastro, C.14
Gasparetto, C.15
Chao, N.J.16
Bigner, D.D.17
-
10
-
-
0017250977
-
DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA
-
doi: 10.1038/260170a0
-
Stehelin D, Varmus HE, Bishop JM, Vogt PK (1976) DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA. Nature 260:170-173. doi: 10.1038/260170a0
-
(1976)
Nature
, vol.260
, pp. 170-173
-
-
Stehelin, D.1
Varmus, H.E.2
Bishop, J.M.3
Vogt, P.K.4
-
11
-
-
0020972413
-
Cellular oncogenes and retroviruses
-
Bishop JM (1983) Cellular oncogenes and retroviruses. Ann Rev biochem 52:301-354
-
(1983)
Ann Rev Biochem
, vol.52
, pp. 301-354
-
-
Bishop, J.M.1
-
12
-
-
0025047659
-
Molecular probes in neuro-oncology: A Review
-
doi: 10.3109/07357909009012060
-
Rutka JT, Trent JM, Rosenblum ML (1990) Molecular probes in neuro-oncology: A Review. Cancer Invest 8:425-438. doi: 10.3109/ 07357909009012060
-
(1990)
Cancer Invest
, vol.8
, pp. 425-438
-
-
Rutka, J.T.1
Trent, J.M.2
Rosenblum, M.L.3
-
13
-
-
0021932240
-
Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin
-
doi: 10.1038/313144a0
-
Libermann TA, Nusbaum HR, Razon N, Kris R, Lax I, Soreq H, Whittle N, Waterfield MD, Ullrich A, Schlessinger J (1985) Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin. Nature 313:144-147. doi: 10.1038/ 313144a0
-
(1985)
Nature
, vol.313
, pp. 144-147
-
-
Libermann, T.A.1
Nusbaum, H.R.2
Razon, N.3
Kris, R.4
Lax, I.5
Soreq, H.6
Whittle, N.7
Waterfield, M.D.8
Ullrich, A.9
Schlessinger, J.10
-
14
-
-
0022372783
-
Amplification and overexpression of the EGF receptor gene in primary human glioblastomas
-
Libermann TA, Nusbaum HR, Razon N, Kris R, Lax I, Soreq H, Whittle N, Waterfield MD, Ullrich A, Schlessinger J (1985) Amplification and overexpression of the EGF receptor gene in primary human glioblastomas. J Cell Sci Suppl 3:161-172
-
(1985)
J Cell Sci Suppl
, vol.3
, pp. 161-172
-
-
Libermann, T.A.1
Nusbaum, H.R.2
Razon, N.3
Kris, R.4
Lax, I.5
Soreq, H.6
Whittle, N.7
Waterfield, M.D.8
Ullrich, A.9
Schlessinger, J.10
-
15
-
-
0023429079
-
Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification
-
doi: 10.1073/pnas.84.19.6899
-
Wong AJ, Bigner SH, Bigner DD, Kinzler KW, Hamilton SR, Vogelstein B (1987) Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification. Proc Natl Acad Sci USA 84:6899-6903. doi: 10.1073/pnas.84.19.6899
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 6899-6903
-
-
Wong, A.J.1
Bigner, S.H.2
Bigner, D.D.3
Kinzler, K.W.4
Hamilton, S.R.5
Vogelstein, B.6
-
16
-
-
0028875936
-
Transfer of genes to humans: Early lessons and obstacles to success
-
doi: 10.1126/science.270.5235.404
-
Crystal RG (1995) Transfer of genes to humans: Early lessons and obstacles to success. Science 270:404-410. doi: 10.1126/ science.270.5235.404
-
(1995)
Science
, vol.270
, pp. 404-410
-
-
Crystal, R.G.1
-
17
-
-
0027595949
-
The basic science of gene therapy
-
doi: 10.1126/science.8493530
-
Mulligan RC (1993) The basic science of gene therapy. Science 260:926-932. doi: 10.1126/science.8493530
-
(1993)
Science
, vol.260
, pp. 926-932
-
-
Mulligan, R.C.1
-
18
-
-
0031770243
-
Viral vectors for gene therapy
-
doi: 10.1016/S0163-7258(98)00020-5
-
Robbins PD, Ghivizzani SC (1998) Viral vectors for gene therapy. Pharmacol Ther 80:35-47. doi: 10.1016/S0163-7258(98)00020-5
-
(1998)
Pharmacol Ther
, vol.80
, pp. 35-47
-
-
Robbins, P.D.1
Ghivizzani, S.C.2
-
19
-
-
0025864440
-
Experimental therapy of human glioma by means of a genetically engineered virus mutant
-
doi: 10.1126/science.1851332
-
Martuza RL, Malick A, Markert JM, Ruffner KL, Coen DM (1991) Experimental therapy of human glioma by means of a genetically engineered virus mutant. Science 252:854-856. doi: 10.1126/ science.1851332
-
(1991)
Science
, vol.252
, pp. 854-856
-
-
Martuza, R.L.1
Malick, A.2
Markert, J.M.3
Ruffner, K.L.4
Coen, D.M.5
-
20
-
-
0031463632
-
Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells
-
doi: 10.1038/nm1297-1354
-
Ram Z, Culver KW, Oshiro EM, Viola JJ, DeVroom HL, Otto E, Long Z, Chiang Y, McGarrity GJ, Muul LM, Katz D, Blaese RM, Oldfield EH (1997) Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells. Nat Med 3:1354-1361. doi: 10.1038/ nm1297-1354
-
(1997)
Nat Med
, vol.3
, pp. 1354-1361
-
-
Ram, Z.1
Culver, K.W.2
Oshiro, E.M.3
Viola, J.J.4
DeVroom, H.L.5
Otto, E.6
Long, Z.7
Chiang, Y.8
McGarrity, G.J.9
Muul, L.M.10
Katz, D.11
Blaese, R.M.12
Oldfield, E.H.13
-
21
-
-
0033000339
-
Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: A pilot study in humans
-
doi: 10.1038/sj.gt.3300805
-
Palu G, Cavaggioni A, Calvi P, Franchin E, Pizzato M, Boschetto R, Parolin C, Chilosi M, Ferrini S, Zanusso A, Colombo F (1999) Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: A pilot study in humans. Gene Ther 6:330-337. doi: 10.1038/sj.gt.3300805
-
(1999)
Gene Ther
, vol.6
, pp. 330-337
-
-
Palu, G.1
Cavaggioni, A.2
Calvi, P.3
Franchin, E.4
Pizzato, M.5
Boschetto, R.6
Parolin, C.7
Chilosi, M.8
Ferrini, S.9
Zanusso, A.10
Colombo, F.11
-
22
-
-
19244362665
-
Treatment of advanced CNS malignancies with the recombinant adenovirus H5.010RSVTK: A phase I trial
-
doi: 10.1089/hum.1996.7.12-1465
-
Eck SL, Alavi JB, Alavi A, Davis A, Hackney D, Judy K, Mollman J, Phillips PC, Wheeldon EB, Wilson JM (1996) Treatment of advanced CNS malignancies with the recombinant adenovirus H5.010RSVTK: A phase I trial. Hum Gene Ther 7:1465-1482. doi: 10.1089/hum.1996.7.12-1465
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1465-1482
-
-
Eck, S.L.1
Alavi, J.B.2
Alavi, A.3
Davis, A.4
Hackney, D.5
Judy, K.6
Mollman, J.7
Phillips, P.C.8
Wheeldon, E.B.9
Wilson, J.M.10
-
23
-
-
2442767029
-
A phase I/II study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for recurrent glioblastoma. Study Group on Gene Therapy for Glioblastoma
-
doi: 10.1089/hum.1998.9.17-2595
-
Klatzmann D, Valery CA, Bensimon G, Marro B, Boyer O, Mokhtari K, Diquet B, Salzmann JL, Philippon J (1998) A phase I/II study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for recurrent glioblastoma. Study Group on Gene Therapy for Glioblastoma. Hum Gene Ther 9:2595-2604. doi: 10.1089/hum.1998.9.17-2595
-
(1998)
Hum Gene Ther
, vol.9
, pp. 2595-2604
-
-
Klatzmann, D.1
Valery, C.A.2
Bensimon, G.3
Marro, B.4
Boyer, O.5
Mokhtari, K.6
Diquet, B.7
Salzmann, J.L.8
Philippon, J.9
-
24
-
-
0029148876
-
Stereotactic injection of herpes simplex thymidine kinase vector producer cells (PA317-G1Tk1SvNa.7) and intravenous ganciclovir for the treatment of progressive or recurrent primary supratentorial pediatric malignant brain tumors
-
doi: 10.1089/hum.1995.6.9-1231
-
Kun LE, Gajjar A, Muhlbauer M, Heideman RL, Sanford R, Brenner M, Walter A, Langston J, Jenkins J, Facchini S (1995) Stereotactic injection of herpes simplex thymidine kinase vector producer cells (PA317-G1Tk1SvNa.7) and intravenous ganciclovir for the treatment of progressive or recurrent primary supratentorial pediatric malignant brain tumors. Hum Gene Ther 6:1231-1255. doi: 10.1089/hum.1995.6.9-1231
-
(1995)
Hum Gene Ther
, vol.6
, pp. 1231-1255
-
-
Kun, L.E.1
Gajjar, A.2
Muhlbauer, M.3
Heideman, R.L.4
Sanford, R.5
Brenner, M.6
Walter, A.7
Langston, J.8
Jenkins, J.9
Facchini, S.10
-
25
-
-
0027548077
-
Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir
-
doi: 10.1089/hum.1993.4.1-39
-
Oldfield EH, Ram Z, Culver KW, Blaese RM, DeVroom HL, Anderson WF (1993) Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir. Hum Gene Ther 4:39-69. doi: 10.1089/hum.1993.4.1-39
-
(1993)
Hum Gene Ther
, vol.4
, pp. 39-69
-
-
Oldfield, E.H.1
Ram, Z.2
Culver, K.W.3
Blaese, R.M.4
DeVroom, H.L.5
Anderson, W.F.6
-
26
-
-
0028124751
-
Gene therapy for the treatment of recurrent pediatric malignant astrocytomas with in vivo tumor transduction with the herpes simplex thymidine kinase gene/ganciclovir system
-
doi: 10.1089/hum.1994.5.7-863
-
Raffel C, Culver K, Kohn D, Nelson M, Siegel S, Gillis F, Link CJ, Villablanca JG, Anderson WF (1994) Gene therapy for the treatment of recurrent pediatric malignant astrocytomas with in vivo tumor transduction with the herpes simplex thymidine kinase gene/ganciclovir system. Hum Gene Ther 5:863-890. doi: 10.1089/hum.1994.5.7-863
-
(1994)
Hum Gene Ther
, vol.5
, pp. 863-890
-
-
Raffel, C.1
Culver, K.2
Kohn, D.3
Nelson, M.4
Siegel, S.5
Gillis, F.6
Link, C.J.7
Villablanca, J.G.8
Anderson, W.F.9
-
27
-
-
0033566061
-
Localization of common deletion regions on 1p and 19q in human gliomas and their association with histological subtype
-
doi: 10.1038/sj.onc.1202759
-
Smith JS, Alderete B, Minn Y, Borell TJ, Perry A, Mohapatra G, Hosek SM, Kimmel D, O'Fallon J, Yates A, Feuerstein BG, Burger PC, Scheithauer BW, Jenkins RB (1999) Localization of common deletion regions on 1p and 19q in human gliomas and their association with histological subtype. Oncogene 18:4144-4152. doi: 10.1038/sj.onc.1202759
-
(1999)
Oncogene
, vol.18
, pp. 4144-4152
-
-
Smith, J.S.1
Alderete, B.2
Minn, Y.3
Borell, T.J.4
Perry, A.5
Mohapatra, G.6
Hosek, S.M.7
Kimmel, D.8
O'Fallon, J.9
Yates, A.10
Feuerstein, B.G.11
Burger, P.C.12
Scheithauer, B.W.13
Jenkins, R.B.14
-
28
-
-
0033055970
-
Congenital disseminated malignant rhabdoid tumor: A distinct clinicopathologic entity demonstrating abnormalities of chromosome 22q11
-
doi: 10.1097/00000478-199903000-00001
-
White FV, Dehner LP, Belchis DA, Conard K, Davis MM, Stocker JT, Zuppan CW, Biegel JA, Perlman EJ (1999) Congenital disseminated malignant rhabdoid tumor: A distinct clinicopathologic entity demonstrating abnormalities of chromosome 22q11. Am J Surg Pathol 23:249-256. doi: 10.1097/00000478-199903000-00001
-
(1999)
Am J Surg Pathol
, vol.23
, pp. 249-256
-
-
White, F.V.1
Dehner, L.P.2
Belchis, D.A.3
Conard, K.4
Davis, M.M.5
Stocker, J.T.6
Zuppan, C.W.7
Biegel, J.A.8
Perlman, E.J.9
-
29
-
-
0026686674
-
Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours
-
doi: 10.1038/359162a0
-
Delattre O, Zucman J, Plougastel B, Desmaze C, Melot T, Peter M, Kovar H, Joubert I, de Jong P, Rouleau G et al (1992) Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours. Nature 359:162-165. doi: 10.1038/359162a0
-
(1992)
Nature
, vol.359
, pp. 162-165
-
-
Delattre, O.1
Zucman, J.2
Plougastel, B.3
Desmaze, C.4
Melot, T.5
Peter, M.6
Kovar, H.7
Joubert, I.8
de Jong, P.9
Rouleau, G.10
-
30
-
-
0032415086
-
Chromosomal aberrations detected by comparative genomic hybridization (CGH) in human astrocytic tumors
-
doi: 10.1016/S0304-3835(98)00266-3
-
Maruno M, Yoshimine T, Muhammad AK, Ninomiya H, Kato A, Hayakawa T (1999) Chromosomal aberrations detected by comparative genomic hybridization (CGH) in human astrocytic tumors. Cancer Lett 135:61-66. doi: 10.1016/S0304-3835(98)00266-3
-
(1999)
Cancer Lett
, vol.135
, pp. 61-66
-
-
Maruno, M.1
Yoshimine, T.2
Muhammad, A.K.3
Ninomiya, H.4
Kato, A.5
Hayakawa, T.6
-
31
-
-
0033860991
-
Molecular cytogenetic analysis of medulloblastomas and supratentorial primitive neuroectodermal tumors by using conventional banding, comparative genomic hybridization, and spectral karyotyping
-
Bayani J, Zielenska M, Marrano P, Kwan Ng Y, Taylor MD, Jay V, Rutka JT, Squire JA (2000) Molecular cytogenetic analysis of medulloblastomas and supratentorial primitive neuroectodermal tumors by using conventional banding, comparative genomic hybridization, and spectral karyotyping. J Neurosurg 93:437-448
-
(2000)
J Neurosurg
, vol.93
, pp. 437-448
-
-
Bayani, J.1
Zielenska, M.2
Marrano, P.3
Kwan Ng, Y.4
Taylor, M.D.5
Jay, V.6
Rutka, J.T.7
Squire, J.A.8
-
32
-
-
0037012881
-
Large-scale transcriptional activity in chromosomes 21 and 22
-
doi: 10.1126/science.1068597
-
Kapranov P, Cawley SE, Drenkow J, Bekiranov S, Strausberg RL, Fodor SP, Gingeras TR (2002) Large-scale transcriptional activity in chromosomes 21 and 22. Science 296:916-919. doi: 10.1126/science.1068597
-
(2002)
Science
, vol.296
, pp. 916-919
-
-
Kapranov, P.1
Cawley, S.E.2
Drenkow, J.3
Bekiranov, S.4
Strausberg, R.L.5
Fodor, S.P.6
Gingeras, T.R.7
-
33
-
-
0036132668
-
Molecular classification of human diffuse gliomas by multidimensional scaling analysis of gene expression profiles parallels morphology-based classification, correlates with survival, and reveals clinically-relevant novel glioma subsets
-
Fuller GN, Hess KR, Rhee CH, Yung WK, Sawaya RA, Bruner JM, Zhang W (2002) Molecular classification of human diffuse gliomas by multidimensional scaling analysis of gene expression profiles parallels morphology-based classification, correlates with survival, and reveals clinically-relevant novel glioma subsets. Brain Pathol 12:108-116
-
(2002)
Brain Pathol
, vol.12
, pp. 108-116
-
-
Fuller, G.N.1
Hess, K.R.2
Rhee, C.H.3
Yung, W.K.4
Sawaya, R.A.5
Bruner, J.M.6
Zhang, W.7
-
34
-
-
40749111022
-
Genomic changes and gene expression profiles reveal that established glioma cell lines are poorly representative of primary human gliomas
-
doi: 10.1158/1541-7786.MCR-07-0280
-
Li A, Walling J, Kotliarov Y, Center A, Steed ME, Ahn SJ, Rosenblum M, Mikkelsen T, Zenklusen JC, Fine HA (2008) Genomic changes and gene expression profiles reveal that established glioma cell lines are poorly representative of primary human gliomas. Mol Cancer Res 6:21-30. doi: 10.1158/1541-7786.MCR-07-0280
-
(2008)
Mol Cancer Res
, vol.6
, pp. 21-30
-
-
Li, A.1
Walling, J.2
Kotliarov, Y.3
Center, A.4
Steed, M.E.5
Ahn, S.J.6
Rosenblum, M.7
Mikkelsen, T.8
Zenklusen, J.C.9
Fine, H.A.10
-
35
-
-
0036682413
-
Gene expression microarray analysis reveals YKL-40 to be a potential serum marker for malignant character in human glioma
-
Tanwar MK, Gilbert MR, Holland EC (2002) Gene expression microarray analysis reveals YKL-40 to be a potential serum marker for malignant character in human glioma. Cancer Res 62:4364-4368
-
(2002)
Cancer Res
, vol.62
, pp. 4364-4368
-
-
Tanwar, M.K.1
Gilbert, M.R.2
Holland, E.C.3
-
36
-
-
0042425741
-
Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction
-
van den Boom J, Wolter M, Kuick R, Misek DE, Youkilis AS, Wechsler DS, Sommer C, Reifenberger G, Hanash SM (2003) Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction. Am J Pathol 163:1033-1043
-
(2003)
Am J Pathol
, vol.163
, pp. 1033-1043
-
-
van den Boom, J.1
Wolter, M.2
Kuick, R.3
Misek, D.E.4
Youkilis, A.S.5
Wechsler, D.S.6
Sommer, C.7
Reifenberger, G.8
Hanash, S.M.9
-
37
-
-
18944395853
-
Robustness of gene expression profiling in glioma specimen samplings and derived cell lines
-
doi: 10.1016/j.molbrainres.2005.01.017
-
Mehrian Shai R, Reichardt JK, Ya-Hsuan H, Kremen TJ, Liau LM, Cloughesy TF, Mischel PS, Nelson SF (2005) Robustness of gene expression profiling in glioma specimen samplings and derived cell lines. Brain Res Mol Brain Res 136:99-103. doi: 10.1016/j.molbrainres.2005.01.017
-
(2005)
Brain Res Mol Brain Res
, vol.136
, pp. 99-103
-
-
Mehrian Shai, R.1
Reichardt, J.K.2
Ya-Hsuan, H.3
Kremen, T.J.4
Liau, L.M.5
Cloughesy, T.F.6
Mischel, P.S.7
Nelson, S.F.8
-
38
-
-
34248545443
-
Gene expression profiling of breast, prostate, and glioma cells following single versus fractionated doses of radiation
-
doi: 10.1158/0008-5472.CAN-06-4250
-
Tsai MH, Cook JA, Chandramouli GV, DeGraff W, Yan H, Zhao S, Coleman CN, Mitchell JB, Chuang EY (2007) Gene expression profiling of breast, prostate, and glioma cells following single versus fractionated doses of radiation. Cancer Res 67:3845-3852. doi: 10.1158/0008-5472.CAN-06-4250
-
(2007)
Cancer Res
, vol.67
, pp. 3845-3852
-
-
Tsai, M.H.1
Cook, J.A.2
Chandramouli, G.V.3
DeGraff, W.4
Yan, H.5
Zhao, S.6
Coleman, C.N.7
Mitchell, J.B.8
Chuang, E.Y.9
-
39
-
-
68949135462
-
The role of the membrane cytoskeleton crosslinker ezrin in medulloblastoma cells
-
doi: 10.1215/15228517-2008-110
-
Osawa H, Smith C, Ra YS, Rutka JT (2009) The role of the membrane cytoskeleton crosslinker ezrin in medulloblastoma cells. Neuro-oncol. doi: 10.1215/15228517-2008-110
-
(2009)
Neuro-oncol
-
-
Osawa, H.1
Smith, C.2
Ra, Y.S.3
Rutka, J.T.4
-
40
-
-
33750441471
-
Current concepts in the molecular genetics of pediatric brain tumors: Implications for emerging therapies
-
doi: 10.1007/s00381-006-0187-3
-
Tamber MS, Bansal K, Liang ML, Mainprize TG, Salhia B, Northcott P, Taylor M, Rutka JT (2006) Current concepts in the molecular genetics of pediatric brain tumors: Implications for emerging therapies. Childs Nerv Syst 22:1379-1394. doi: 10.1007/s00381-006-0187-3
-
(2006)
Childs Nerv Syst
, vol.22
, pp. 1379-1394
-
-
Tamber, M.S.1
Bansal, K.2
Liang, M.L.3
Mainprize, T.G.4
Salhia, B.5
Northcott, P.6
Taylor, M.7
Rutka, J.T.8
-
41
-
-
2342468007
-
Application of bacterial artificial chromosome array-based comparative genomic hybridization and spectral karyotyping to the analysis of glioblastoma multiforme
-
doi: 10.1016/j.cancergencyto.2003.09.012
-
Cowell JK, Matsui S, Wang YD, LaDuca J, Conroy J, McQuaid D, Nowak NJ (2004) Application of bacterial artificial chromosome array-based comparative genomic hybridization and spectral karyotyping to the analysis of glioblastoma multiforme. Cancer Genet Cytogenet 151:36-51. doi: 10.1016/j.cancergencyto.2003.09.012
-
(2004)
Cancer Genet Cytogenet
, vol.151
, pp. 36-51
-
-
Cowell, J.K.1
Matsui, S.2
Wang, Y.D.3
LaDuca, J.4
Conroy, J.5
McQuaid, D.6
Nowak, N.J.7
-
42
-
-
24944535651
-
Identification of a novel homozygous deletion region at 6q23.1 in medulloblastomas using high-resolution array comparative genomic hybridization analysis
-
doi: 10.1158/1078-0432.CCR-05-0128
-
Hui AB, Takano H, Lo KW, Kuo WL, Lam CN, Tong CY, Chang Q, Gray JW, Ng HK (2005) Identification of a novel homozygous deletion region at 6q23.1 in medulloblastomas using high-resolution array comparative genomic hybridization analysis. Clin Cancer Res 11:4707-4716. doi: 10.1158/ 1078-0432.CCR-05-0128
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4707-4716
-
-
Hui, A.B.1
Takano, H.2
Lo, K.W.3
Kuo, W.L.4
Lam, C.N.5
Tong, C.Y.6
Chang, Q.7
Gray, J.W.8
Ng, H.K.9
-
43
-
-
32544441908
-
Array CGH analysis of pediatric medulloblastomas
-
doi: 10.1002/gcc.20292
-
Rossi MR, Conroy J, McQuaid D, Nowak NJ, Rutka JT, Cowell JK (2006) Array CGH analysis of pediatric medulloblastomas. Genes Chromosomes Cancer 45:290-303. doi: 10.1002/gcc.20292
-
(2006)
Genes Chromosomes Cancer
, vol.45
, pp. 290-303
-
-
Rossi, M.R.1
Conroy, J.2
McQuaid, D.3
Nowak, N.J.4
Rutka, J.T.5
Cowell, J.K.6
-
44
-
-
26644435531
-
Radial glia cells are candidate stem cells of ependymoma
-
doi: 10.1016/j.ccr.2005.09.001
-
Taylor MD, Poppleton H, Fuller C, Su X, Liu Y, Jensen P, Magdaleno S, Dalton J, Calabrese C, Board J, Macdonald T, Rutka J, Guha A, Gajjar A, Curran T, Gilbertson RJ (2005) Radial glia cells are candidate stem cells of ependymoma. Cancer Cell 8:323-335. doi: 10.1016/ j.ccr.2005.09.001
-
(2005)
Cancer Cell
, vol.8
, pp. 323-335
-
-
Taylor, M.D.1
Poppleton, H.2
Fuller, C.3
Su, X.4
Liu, Y.5
Jensen, P.6
Magdaleno, S.7
Dalton, J.8
Calabrese, C.9
Board, J.10
Macdonald, T.11
Rutka, J.12
Guha, A.13
Gajjar, A.14
Curran, T.15
Gilbertson, R.J.16
-
45
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Cancer genome atlas research network doi: 10.1038/nature07385
-
Cancer genome atlas research network (2008) Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455:1061-1068. doi: 10.1038/nature07385
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
46
-
-
63449115501
-
Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma
-
doi: 10.1038/ng.336
-
Northcott P, Nakahara Y, Xiaochong W, et al. (2009) Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma. Nature Genetics. doi: 10.1038/ng.336
-
(2009)
Nature Genetics
-
-
Northcott, P.1
Nakahara, Y.2
Xiaochong, W.3
-
47
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
doi: 10.1101/gad.947102
-
Bird A (2002) DNA methylation patterns and epigenetic memory. Genes Dev 16:6-21. doi: 10.1101/gad.947102
-
(2002)
Genes Dev
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
48
-
-
35848951163
-
Covalent modifications of histones during development and disease pathogenesis
-
doi: 10.1038/nsmb1337
-
Bhaumik SR, Smith E, Shilatifard A (2007) Covalent modifications of histones during development and disease pathogenesis. Nat Struct Mol Biol 14:1008-1016. doi: 10.1038/nsmb1337
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 1008-1016
-
-
Bhaumik, S.R.1
Smith, E.2
Shilatifard, A.3
-
49
-
-
36549056015
-
Epigenetic changes in cancer
-
doi: 10.1111/j.1600-0463.2007.apm_636.xml.x
-
Gronbaek K, Hother C, Jones PA (2007) Epigenetic changes in cancer. APMIS 115:1039-1059. doi: 10.1111/j.1600-0463.2007.apm_636.xml.x
-
(2007)
APMIS
, vol.115
, pp. 1039-1059
-
-
Gronbaek, K.1
Hother, C.2
Jones, P.A.3
-
50
-
-
24344509239
-
TP53 promoter methylation in human gliomas
-
doi: 10.1007/s00401-005-1041-5
-
Amatya VJ, Naumann U, Weller M, Ohgaki H (2005) TP53 promoter methylation in human gliomas. Acta Neuropathol 110:178-184. doi: 10.1007/ s00401-005-1041-5
-
(2005)
Acta Neuropathol
, vol.110
, pp. 178-184
-
-
Amatya, V.J.1
Naumann, U.2
Weller, M.3
Ohgaki, H.4
-
51
-
-
0142061145
-
PTEN methylation and expression in glioblastomas
-
doi: 10.1007/s00401-003-0748-4
-
Baeza N, Weller M, Yonekawa Y, Kleihues P, Ohgaki H (2003) PTEN methylation and expression in glioblastomas. Acta Neuropathol 106:479-485. doi: 10.1007/s00401-003-0748-4
-
(2003)
Acta Neuropathol
, vol.106
, pp. 479-485
-
-
Baeza, N.1
Weller, M.2
Yonekawa, Y.3
Kleihues, P.4
Ohgaki, H.5
-
52
-
-
34547432233
-
Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastoma
-
doi: 10.1215/15228517-2007-003
-
Wiencke JK, Zheng S, Jelluma N, Tihan T, Vandenberg S, Tamguney T, Baumber R, Parsons R, Lamborn KR, Berger MS, Wrensch MR, Haas-Kogan DA, Stokoe D (2007) Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastoma. Neuro-oncol 9:271-279. doi: 10.1215/ 15228517-2007-003
-
(2007)
Neuro-oncol
, vol.9
, pp. 271-279
-
-
Wiencke, J.K.1
Zheng, S.2
Jelluma, N.3
Tihan, T.4
Vandenberg, S.5
Tamguney, T.6
Baumber, R.7
Parsons, R.8
Lamborn, K.R.9
Berger, M.S.10
Wrensch, M.R.11
Haas-Kogan, D.A.12
Stokoe, D.13
-
53
-
-
33746163546
-
Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma
-
doi: 10.1158/0008-5472.CAN-05-4453
-
Foltz G, Ryu GY, Yoon JG, Nelson T, Fahey J, Frakes A, Lee H, Field L, Zander K, Sibenaller Z, Ryken TC, Vibhakar R, Hood L, Madan A (2006) Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma. Cancer Res 66:6665-6674. doi: 10.1158/0008-5472.CAN-05-4453
-
(2006)
Cancer Res
, vol.66
, pp. 6665-6674
-
-
Foltz, G.1
Ryu, G.Y.2
Yoon, J.G.3
Nelson, T.4
Fahey, J.5
Frakes, A.6
Lee, H.7
Field, L.8
Zander, K.9
Sibenaller, Z.10
Ryken, T.C.11
Vibhakar, R.12
Hood, L.13
Madan, A.14
-
54
-
-
33747889966
-
Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma
-
doi: 10.1158/0008-5472.CAN-05-4552
-
Kim TY, Zhong S, Fields CR, Kim JH, Robertson KD (2006) Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma. Cancer Res 66:7490-7501. doi: 10.1158/0008-5472.CAN-05-4552
-
(2006)
Cancer Res
, vol.66
, pp. 7490-7501
-
-
Kim, T.Y.1
Zhong, S.2
Fields, C.R.3
Kim, J.H.4
Robertson, K.D.5
-
55
-
-
36549077591
-
Brain cancer stem-like cell genesis from p53-deficient mouse astrocytes by oncogenic Ras
-
doi: 10.1016/j.bbrc.2007.11.005
-
Lee JS, Gil JE, Kim JH, Kim TK, Jin X, Oh SY, Sohn YW, Jeon HM, Park HJ, Park JW, Shin YJ, Chung YG, Lee JB, You S, Kim H (2008) Brain cancer stem-like cell genesis from p53-deficient mouse astrocytes by oncogenic Ras. Biochem Biophys Res Commun 365:496-502. doi: 10.1016/ j.bbrc.2007.11.005
-
(2008)
Biochem Biophys Res Commun
, vol.365
, pp. 496-502
-
-
Lee, J.S.1
Gil, J.E.2
Kim, J.H.3
Kim, T.K.4
Jin, X.5
Oh, S.Y.6
Sohn, Y.W.7
Jeon, H.M.8
Park, H.J.9
Park, J.W.10
Shin, Y.J.11
Chung, Y.G.12
Lee, J.B.13
You, S.14
Kim, H.15
-
56
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
doi: 10.1056/NEJMoa043331
-
Hegi ME, Diserens AC, Gorlia T, Hamou MF, de Tribolet N, Weller M, Kros JM, Hainfellner JA, Mason W, Mariani L, Bromberg JE, Hau P, Mirimanoff RO, Cairncross JG, Janzer RC, Stupp R (2005) MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 352:997-1003. doi: 10.1056/NEJMoa043331
-
(2005)
N Engl J Med
, vol.352
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
Hamou, M.F.4
de Tribolet, N.5
Weller, M.6
Kros, J.M.7
Hainfellner, J.A.8
Mason, W.9
Mariani, L.10
Bromberg, J.E.11
Hau, P.12
Mirimanoff, R.O.13
Cairncross, J.G.14
Janzer, R.C.15
Stupp, R.16
-
57
-
-
36749086010
-
Epigenetic aberrations in malignant gliomas: An open door leading to better understanding and treatment
-
Martinez R, Schackert G (2007) Epigenetic aberrations in malignant gliomas: An open door leading to better understanding and treatment. Epigenetics 2:147-150
-
(2007)
Epigenetics
, vol.2
, pp. 147-150
-
-
Martinez, R.1
Schackert, G.2
-
59
-
-
57149094865
-
An genome wide screen identifies SPINT2 as a novel tumor suppressor silenced by methylation in medulloblastoma
-
doi: 10.1158/0008-5472.CAN-08-2169
-
Kongkham P, Northcott P, Taylor MD, Smith C, Mainprize T, Croul S, Rutka JT (2008) An genome wide screen identifies SPINT2 as a novel tumor suppressor silenced by methylation in medulloblastoma. Cancer Res 68:9945-9953. doi: 10.1158/0008-5472.CAN-08-2169
-
(2008)
Cancer Res
, vol.68
, pp. 9945-9953
-
-
Kongkham, P.1
Northcott, P.2
Taylor, M.D.3
Smith, C.4
Mainprize, T.5
Croul, S.6
Rutka, J.T.7
-
60
-
-
34147215025
-
Dickkopf-1 is an epigenetically silenced candidate tumor suppressor gene in medulloblastoma
-
doi: 10.1215/15228517-2006-038
-
Vibhakar R, Foltz G, Yoon JG, Field L, Lee H, Ryu GY, Pierson J, Davidson B, Madan A (2007) Dickkopf-1 is an epigenetically silenced candidate tumor suppressor gene in medulloblastoma. Neuro-oncol 9:135-144. doi: 10.1215/15228517-2006-038
-
(2007)
Neuro-oncol
, vol.9
, pp. 135-144
-
-
Vibhakar, R.1
Foltz, G.2
Yoon, J.G.3
Field, L.4
Lee, H.5
Ryu, G.Y.6
Pierson, J.7
Davidson, B.8
Madan, A.9
-
61
-
-
0027751663
-
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
doi: 10.1016/0092-8674(93)90529-Y
-
Lee RC, Feinbaum RL, Ambros V (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75:843-854. doi: 10.1016/0092-8674(93)90529-Y
-
(1993)
Cell
, vol.75
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
62
-
-
0027730383
-
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
-
doi: 10.1016/0092-8674(93)90530-4
-
Wightman B, Ha I, Ruvkun G (1993) Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75:855-862. doi: 10.1016/0092-8674(93)90530-4
-
(1993)
Cell
, vol.75
, pp. 855-862
-
-
Wightman, B.1
Ha, I.2
Ruvkun, G.3
-
64
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
doi: 10.1016/S0092-8674(04)00045-5
-
Bartel DP (2004) MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell 116:281-297. doi: 10.1016/S0092-8674(04)00045-5
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
65
-
-
28044471565
-
MicroRNA functions in animal development and human disease
-
doi: 10.1242/dev.02073
-
Alvarez-Garcia I, Miska EA (2005) MicroRNA functions in animal development and human disease. Development 132:4653-4662. doi: 10.1242/ dev.02073
-
(2005)
Development
, vol.132
, pp. 4653-4662
-
-
Alvarez-Garcia, I.1
Miska, E.A.2
-
66
-
-
39749110083
-
Small non-coding RNAs in animal development
-
doi: 10.1038/nrm2347
-
Stefani G, Slack FJ (2008) Small non-coding RNAs in animal development. Nat Rev Mol Cell Biol 9:219-230. doi: 10.1038/nrm2347
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 219-230
-
-
Stefani, G.1
Slack, F.J.2
-
67
-
-
33750370444
-
MicroRNA signatures in human cancers
-
doi: 10.1038/nrc1997
-
Calin GA, Croce CM (2006) MicroRNA signatures in human cancers. Nat Rev Cancer 6:857-866. doi: 10.1038/nrc1997
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
68
-
-
33645294070
-
Oncomirs - MicroRNAs with a role in cancer
-
doi: 10.1038/nrc1840
-
Esquela-Kerscher A, Slack FJ (2006) Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer 6:259-269. doi: 10.1038/nrc1840
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 259-269
-
-
Esquela-Kerscher, A.1
Slack, F.J.2
-
69
-
-
30644475098
-
MicroRNAs as oncogenes
-
doi: 10.1016/j.gde.2005.12.005
-
Hammond SM (2006) MicroRNAs as oncogenes. Curr Opin Genet Dev 16:4-9. doi: 10.1016/j.gde.2005.12.005
-
(2006)
Curr Opin Genet Dev
, vol.16
, pp. 4-9
-
-
Hammond, S.M.1
-
70
-
-
13944282215
-
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
-
doi: 10.1038/nature03315
-
Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, Castle J, Bartel DP, Linsley PS, Johnson JM (2005) Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433:769-773. doi: 10.1038/nature03315
-
(2005)
Nature
, vol.433
, pp. 769-773
-
-
Lim, L.P.1
Lau, N.C.2
Garrett-Engele, P.3
Grimson, A.4
Schelter, J.M.5
Castle, J.6
Bartel, D.P.7
Linsley, P.S.8
Johnson, J.M.9
-
71
-
-
18744396337
-
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
-
doi: 10.1073/pnas.242606799
-
Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, Noch E, Aldler H, Rattan S, Keating M, Rai K, Rassenti L, Kipps T, Negrini M, Bullrich F, Croce CM (2002) Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 99:15524-15529. doi: 10.1073/pnas.242606799
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 15524-15529
-
-
Calin, G.A.1
Dumitru, C.D.2
Shimizu, M.3
Bichi, R.4
Zupo, S.5
Noch, E.6
Aldler, H.7
Rattan, S.8
Keating, M.9
Rai, K.10
Rassenti, L.11
Kipps, T.12
Negrini, M.13
Bullrich, F.14
Croce, C.M.15
-
72
-
-
12144290519
-
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
-
doi: 10.1073/pnas.0307323101
-
Calin GA, Sevignani C, Dumitru CD, Hyslop T, Noch E, Yendamuri S, Shimizu M, Rattan S, Bullrich F, Negrini M, Croce CM (2004) Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci USA 101:2999-3004. doi: 10.1073/pnas.0307323101
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2999-3004
-
-
Calin, G.A.1
Sevignani, C.2
Dumitru, C.D.3
Hyslop, T.4
Noch, E.5
Yendamuri, S.6
Shimizu, M.7
Rattan, S.8
Bullrich, F.9
Negrini, M.10
Croce, C.M.11
-
73
-
-
41949102707
-
miRiad roles for the miR-17-92 cluster in development and disease
-
doi: 10.1016/j.cell.2008.04.001
-
Mendell JT (2008) miRiad roles for the miR-17-92 cluster in development and disease. Cell 133:217-222. doi: 10.1016/j.cell.2008.04.001
-
(2008)
Cell
, vol.133
, pp. 217-222
-
-
Mendell, J.T.1
-
74
-
-
27544495514
-
A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation
-
doi: 10.1158/0008-5472.CAN-05-2352
-
Hayashita Y, Osada H, Tatematsu Y, Yamada H, Yanagisawa K, Tomida S, Yatabe Y, Kawahara K, Sekido Y, Takahashi T (2005) A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res 65:9628-9632. doi: 10.1158/ 0008-5472.CAN-05-2352
-
(2005)
Cancer Res
, vol.65
, pp. 9628-9632
-
-
Hayashita, Y.1
Osada, H.2
Tatematsu, Y.3
Yamada, H.4
Yanagisawa, K.5
Tomida, S.6
Yatabe, Y.7
Kawahara, K.8
Sekido, Y.9
Takahashi, T.10
-
75
-
-
20444467290
-
A microRNA polycistron as a potential human oncogene
-
doi: 10.1038/nature03552
-
He L, Thomson JM, Hemann MT, Hernando-Monge E, Mu D, Goodson S, Powers S, Cordon-Cardo C, Lowe SW, Hannon GJ, Hammond SM (2005) A microRNA polycistron as a potential human oncogene. Nature 435:828-833. doi: 10.1038/nature03552
-
(2005)
Nature
, vol.435
, pp. 828-833
-
-
He, L.1
Thomson, J.M.2
Hemann, M.T.3
Hernando-Monge, E.4
Mu, D.5
Goodson, S.6
Powers, S.7
Cordon-Cardo, C.8
Lowe, S.W.9
Hannon, G.J.10
Hammond, S.M.11
-
76
-
-
0346727383
-
High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma
-
doi: 10.1002/gcc.10316
-
Metzler M, Wilda M, Busch K, Viehmann S, Borkhardt A (2004) High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma. Genes Chromosomes Cancer 39:167-169. doi: 10.1002/gcc.10316
-
(2004)
Genes Chromosomes Cancer
, vol.39
, pp. 167-169
-
-
Metzler, M.1
Wilda, M.2
Busch, K.3
Viehmann, S.4
Borkhardt, A.5
-
77
-
-
22244467087
-
MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
-
doi: 10.1158/0008-5472.CAN-05-0137
-
Chan JA, Krichevsky AM, Kosik KS (2005) MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 65:6029-6033. doi: 10.1158/0008-5472.CAN-05-0137
-
(2005)
Cancer Res
, vol.65
, pp. 6029-6033
-
-
Chan, J.A.1
Krichevsky, A.M.2
Kosik, K.S.3
-
78
-
-
33144490646
-
A microRNA expression signature of human solid tumors defines cancer gene targets
-
doi: 10.1073/pnas.0510565103
-
Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, Petrocca F, Visone R, Iorio M, Roldo C, Ferracin M, Prueitt RL, Yanaihara N, Lanza G, Scarpa A, Vecchione A, Negrini M, Harris CC, Croce CM (2006) A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 103:2257-2261. doi: 10.1073/pnas.0510565103
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2257-2261
-
-
Volinia, S.1
Calin, G.A.2
Liu, C.G.3
Ambs, S.4
Cimmino, A.5
Petrocca, F.6
Visone, R.7
Iorio, M.8
Roldo, C.9
Ferracin, M.10
Prueitt, R.L.11
Yanaihara, N.12
Lanza, G.13
Scarpa, A.14
Vecchione, A.15
Negrini, M.16
Harris, C.C.17
Croce, C.M.18
-
79
-
-
2542626605
-
Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival
-
doi: 10.1158/0008-5472.CAN-04-0637
-
Takamizawa J, Konishi H, Yanagisawa K, Tomida S, Osada H, Endoh H, Harano T, Yatabe Y, Nagino M, Nimura Y, Mitsudomi T, Takahashi T (2004) Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res 64:3753-3756. doi: 10.1158/0008-5472.CAN-04-0637
-
(2004)
Cancer Res
, vol.64
, pp. 3753-3756
-
-
Takamizawa, J.1
Konishi, H.2
Yanagisawa, K.3
Tomida, S.4
Osada, H.5
Endoh, H.6
Harano, T.7
Yatabe, Y.8
Nagino, M.9
Nimura, Y.10
Mitsudomi, T.11
Takahashi, T.12
-
80
-
-
20044395613
-
RAS is regulated by the let-7 microRNA family
-
doi: 10.1016/j.cell.2005.01.014
-
Johnson SM, Grosshans H, Shingara J, Byrom M, Jarvis R, Cheng A, Labourier E, Reinert KL, Brown D, Slack FJ (2005) RAS is regulated by the let-7 microRNA family. Cell 120:635-647. doi: 10.1016/ j.cell.2005.01.014
-
(2005)
Cell
, vol.120
, pp. 635-647
-
-
Johnson, S.M.1
Grosshans, H.2
Shingara, J.3
Byrom, M.4
Jarvis, R.5
Cheng, A.6
Labourier, E.7
Reinert, K.L.8
Brown, D.9
Slack, F.J.10
-
81
-
-
35148900227
-
MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas
-
doi: 10.1158/0008-5472.CAN-07-1045
-
Corsten MF, Miranda R, Kasmieh R, Krichevsky AM, Weissleder R, Shah K (2007) MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas. Cancer Res 67:8994-9000. doi: 10.1158/ 0008-5472.CAN-07-1045
-
(2007)
Cancer Res
, vol.67
, pp. 8994-9000
-
-
Corsten, M.F.1
Miranda, R.2
Kasmieh, R.3
Krichevsky, A.M.4
Weissleder, R.5
Shah, K.6
-
82
-
-
48949116262
-
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
-
doi: 10.1186/1741-7015-6-14
-
Silber J, Lim DA, Petritsch C, Persson AI, Maunakea AK, Yu M, Vandenberg SR, Ginzinger DG, James CD, Costello JF, Bergers G, Weiss WA, Alvarez-Buylla A, Hodgson JG (2008) miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. BMC Med 6:14. doi: 10.1186/ 1741-7015-6-14
-
(2008)
BMC Med
, vol.6
, pp. 14
-
-
Silber, J.1
Lim, D.A.2
Petritsch, C.3
Persson, A.I.4
Maunakea, A.K.5
Yu, M.6
Vandenberg, S.R.7
Ginzinger, D.G.8
James, C.D.9
Costello, J.F.10
Bergers, G.11
Weiss, W.A.12
Alvarez-Buylla, A.13
Hodgson, J.G.14
-
83
-
-
46349109152
-
Regulation of cyclin dependent kinase 6 by microRNA 124 in medulloblastoma
-
doi: 10.1007/s11060-008-9624-3
-
Pierson J, Hostager B, Fan R, Vibhakar R (2008) Regulation of cyclin dependent kinase 6 by microRNA 124 in medulloblastoma. J Neurooncol 90:1-7. doi: 10.1007/s11060-008-9624-3
-
(2008)
J Neurooncol
, vol.90
, pp. 1-7
-
-
Pierson, J.1
Hostager, B.2
Fan, R.3
Vibhakar, R.4
-
84
-
-
56449126945
-
Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal
-
doi: 10.1158/0008-5472.CAN-08-2629
-
Godlewski J, Nowicki MO, Bronisz A, Williams S, Otsuki A, Nuovo G, Raychaudhury A, Newton HB, Chiocca EA, Lawler S (2008) Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal. Cancer Res 68:9125-9130. doi: 10.1158/ 0008-5472.CAN-08-2629
-
(2008)
Cancer Res
, vol.68
, pp. 9125-9130
-
-
Godlewski, J.1
Nowicki, M.O.2
Bronisz, A.3
Williams, S.4
Otsuki, A.5
Nuovo, G.6
Raychaudhury, A.7
Newton, H.B.8
Chiocca, E.A.9
Lawler, S.10
-
85
-
-
65249186793
-
The miR-17/92 polycistron is amplified and upregulated in Sonic Hedgehog-drive medulloblastomas and induced by N-Myc in Sonic Hedgehog-treated cerebellar neural precursors
-
(in press)
-
Northcott P, Fernandez-Li A, Hagah JP, Ellison DW, Grajkowska W, Gillespie Y, Grundy R, Van Meter T, Rutka JT, Croce CM, Kenney AM, Taylor MD (2009) The miR-17/92 polycistron is amplified and upregulated in Sonic Hedgehog-drive medulloblastomas and induced by N-Myc in Sonic Hedgehog-treated cerebellar neural precursors. Cancer Res (in press)
-
(2009)
Cancer Res
-
-
Northcott, P.1
Fernandez-Li, A.2
Hagah, J.P.3
Ellison, D.W.4
Grajkowska, W.5
Gillespie, Y.6
Grundy, R.7
Van Meter, T.8
Rutka, J.T.9
Croce, C.M.10
Kenney, A.M.11
Taylor, M.D.12
-
86
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
doi: 10.1126/science.1164382
-
Parsons DW, Jones S, Zhang X, Lin JC, Leary RJ, Angenendt P, Mankoo P, Carter H, Siu IM, Gallia GL, Olivi A, McLendon R, Rasheed BA, Keir S, Nikolskaya T, Nikolsky Y, Busam DA, Tekleab H, Diaz LA Jr, Hartigan J, Smith DR, Strausberg RL, Marie SK, Shinjo SM, Yan H, Riggins GJ, Bigner DD, Karchin R, Papadopoulos N, Parmigiani G, Vogelstein B, Velculescu VE, Kinzler KW (2008) An integrated genomic analysis of human glioblastoma multiforme. Science 321:1807-1812. doi: 10.1126/ science.1164382
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
Lin, J.C.4
Leary, R.J.5
Angenendt, P.6
Mankoo, P.7
Carter, H.8
Siu, I.M.9
Gallia, G.L.10
Olivi, A.11
McLendon, R.12
Rasheed, B.A.13
Keir, S.14
Nikolskaya, T.15
Nikolsky, Y.16
Busam, D.A.17
Tekleab, H.18
Diaz Jr., L.A.19
Hartigan, J.20
Smith, D.R.21
Strausberg, R.L.22
Marie, S.K.23
Shinjo, S.M.24
Yan, H.25
Riggins, G.J.26
Bigner, D.D.27
Karchin, R.28
Papadopoulos, N.29
Parmigiani, G.30
Vogelstein, B.31
Velculescu, V.E.32
Kinzler, K.W.33
more..
-
87
-
-
37749025169
-
Primer: Sequencing-the next generation
-
doi: 10.1038/nmeth1155
-
Rusk N, Kiermer V (2008) Primer: Sequencing-the next generation. Nat Methods 5:15. doi: 10.1038/nmeth1155
-
(2008)
Nat Methods
, vol.5
, pp. 15
-
-
Rusk, N.1
Kiermer, V.2
-
88
-
-
36549021060
-
Genome-wide in situ exon capture for selective resequencing
-
doi: 10.1038/ng.2007.42
-
Hodges E, Xuan Z, Balija V, Kramer M, Molla MN, Smith SW, Middle CM, Rodesch MJ, Albert TJ, Hannon GJ, McCombie WR (2007) Genome-wide in situ exon capture for selective resequencing. Nat Genet 39:1522-1527. doi: 10.1038/ng.2007.42
-
(2007)
Nat Genet
, vol.39
, pp. 1522-1527
-
-
Hodges, E.1
Xuan, Z.2
Balija, V.3
Kramer, M.4
Molla, M.N.5
Smith, S.W.6
Middle, C.M.7
Rodesch, M.J.8
Albert, T.J.9
Hannon, G.J.10
McCombie, W.R.11
-
89
-
-
44349191457
-
Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing
-
doi: 10.1038/ng.128
-
Campbell PJ, Stephens PJ, Pleasance ED, O'Meara S, Li H, Santarius T, Stebbings LA, Leroy C, Edkins S, Hardy C, Teague JW, Menzies A, Goodhead I, Turner DJ, Clee CM, Quail MA, Cox A, Brown C, Durbin R, Hurles ME, Edwards PA, Bignell GR, Stratton MR, Futreal PA (2008) Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing. Nat Genet 40:722-729. doi: 10.1038/ng.128
-
(2008)
Nat Genet
, vol.40
, pp. 722-729
-
-
Campbell, P.J.1
Stephens, P.J.2
Pleasance, E.D.3
O'Meara, S.4
Li, H.5
Santarius, T.6
Stebbings, L.A.7
Leroy, C.8
Edkins, S.9
Hardy, C.10
Teague, J.W.11
Menzies, A.12
Goodhead, I.13
Turner, D.J.14
Clee, C.M.15
Quail, M.A.16
Cox, A.17
Brown, C.18
Durbin, R.19
Hurles, M.E.20
Edwards, P.A.21
Bignell, G.R.22
Stratton, M.R.23
Futreal, P.A.24
more..
-
90
-
-
44649117905
-
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
-
doi: 10.1016/j.cell.2008.04.043
-
Chen X, Xu H, Yuan P, Fang F, Huss M, Vega VB, Wong E, Orlov YL, Zhang W, Jiang J, Loh YH, Yeo HC, Yeo ZX, Narang V, Govindarajan KR, Leong B, Shahab A, Ruan Y, Bourque G, Sung WK, Clarke ND, Wei CL, Ng HH (2008) Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133:1106-1117. doi: 10.1016/ j.cell.2008.04.043
-
(2008)
Cell
, vol.133
, pp. 1106-1117
-
-
Chen, X.1
Xu, H.2
Yuan, P.3
Fang, F.4
Huss, M.5
Vega, V.B.6
Wong, E.7
Orlov, Y.L.8
Zhang, W.9
Jiang, J.10
Loh, Y.H.11
Yeo, H.C.12
Yeo, Z.X.13
Narang, V.14
Govindarajan, K.R.15
Leong, B.16
Shahab, A.17
Ruan, Y.18
Bourque, G.19
Sung, W.K.20
Clarke, N.D.21
Wei, C.L.22
Ng, H.H.23
more..
-
91
-
-
57149096220
-
Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding
-
Robertson AG, Bilenky M, Tam A, Zhao Y, Zeng T, Thiessen N, Cezard T, Fejes AP, Wederell ED, Cullum R, Euskirchen G, Krzywinski M, Birol I, Snyder M, Hoodless PA, Hirst M, Marra MA, Jones SJ (2008) Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding. Genome Res 18:1906-1917
-
(2008)
Genome Res
, vol.18
, pp. 1906-1917
-
-
Robertson, A.G.1
Bilenky, M.2
Tam, A.3
Zhao, Y.4
Zeng, T.5
Thiessen, N.6
Cezard, T.7
Fejes, A.P.8
Wederell, E.D.9
Cullum, R.10
Euskirchen, G.11
Krzywinski, M.12
Birol, I.13
Snyder, M.14
Hoodless, P.A.15
Hirst, M.16
Marra, M.A.17
Jones, S.J.18
-
92
-
-
34547633677
-
Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing
-
doi: 10.1038/nmeth1068
-
Robertson G, Hirst M, Bainbridge M, Bilenky M, Zhao Y, Zeng T, Euskirchen G, Bernier B, Varhol R, Delaney A, Thiessen N, Griffith OL, He A, Marra M, Snyder M, Jones S (2007) Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing. Nat Methods 4:651-657. doi: 10.1038/nmeth1068
-
(2007)
Nat Methods
, vol.4
, pp. 651-657
-
-
Robertson, G.1
Hirst, M.2
Bainbridge, M.3
Bilenky, M.4
Zhao, Y.5
Zeng, T.6
Euskirchen, G.7
Bernier, B.8
Varhol, R.9
Delaney, A.10
Thiessen, N.11
Griffith, O.L.12
He, A.13
Marra, M.14
Snyder, M.15
Jones, S.16
-
93
-
-
46249106990
-
Mapping and quantifying mammalian transcriptomes by RNA-Seq
-
doi: 10.1038/nmeth.1226
-
Mortazavi A, Williams BA, McCue K, Schaeffer L, Wold B (2008) Mapping and quantifying mammalian transcriptomes by RNA-Seq. Nat Methods 5:621-628. doi: 10.1038/nmeth.1226
-
(2008)
Nat Methods
, vol.5
, pp. 621-628
-
-
Mortazavi, A.1
Williams, B.A.2
McCue, K.3
Schaeffer, L.4
Wold, B.5
-
94
-
-
56749098074
-
Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
-
doi: 10.1038/ng.259
-
Pan Q, Shai O, Lee LJ, Frey BJ, Blencowe BJ (2008) Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing. Nat Genet 40:1413-1415. doi: 10.1038/ng.259
-
(2008)
Nat Genet
, vol.40
, pp. 1413-1415
-
-
Pan, Q.1
Shai, O.2
Lee, L.J.3
Frey, B.J.4
Blencowe, B.J.5
|