Structural Insights into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2

Molecular Cell

Volumn 34, Issue 2, 2009, Pages 223-233

  Bunney, Tom D ^a   Opaleye, Olaniyi ^a   Roe, S Mark ^a   Vatter, Petra ^b   Baxendale, Rhona W ^a   Walliser, Claudia ^b   Everett, Katy L ^a   Josephs, Michelle B ^a   Christow, Carolin ^b   Rodrigues Lima, Fernando ^c   Gierschik, Peter ^b   Pearl, Laurence H ^a   Katan, Matilda ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY HOSPITAL ULM   (Germany)

^c UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

SIGNALING

Indexed keywords

EPIDERMAL GROWTH FACTOR; GUANOSINE DIPHOSPHATE; PHOSPHOLIPASE C GAMMA2; PLECKSTRIN; RAC2 PROTEIN;

ARTICLE; BINDING AFFINITY; CELL STRAIN COS7; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVATION; INSECT CELL; NONHUMAN; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHOLIPASE C GAMMA; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; RAC GTP-BINDING PROTEINS; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 64749102105     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2009.02.023     Document Type: Article

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