-
1
-
-
5444235922
-
LXR-dependent gene expression is important for macrophage survival and the innate immune response
-
Joseph SB, Bradley MN, Castrillo A, Bruhn KW, Mak PA, Pei L, Hogenesch J, O'Connell RM, Cheng G, Saez E, Miller JF, Tontonoz P 2004 LXR-dependent gene expression is important for macrophage survival and the innate immune response. Cell 119:299-309
-
(2004)
Cell
, vol.119
, pp. 299-309
-
-
Joseph, S.B.1
Bradley, M.N.2
Castrillo, A.3
Bruhn, K.W.4
Mak, P.A.5
Pei, L.6
Hogenesch, J.7
O'Connell, R.M.8
Cheng, G.9
Saez, E.10
Miller, J.F.11
Tontonoz, P.12
-
2
-
-
24144490445
-
LXRs regulate the balance between fat storage and oxidation
-
Kalaany NY, Gauthier KC, Zavacki AM, Mammen PP, Kitazume T, Peterson JA, Horton JD, Garry DJ, Bianco AC, Mangelsdorf DJ 2005 LXRs regulate the balance between fat storage and oxidation. Cell Metab 1:231-244
-
(2005)
Cell Metab
, vol.1
, pp. 231-244
-
-
Kalaany, N.Y.1
Gauthier, K.C.2
Zavacki, A.M.3
Mammen, P.P.4
Kitazume, T.5
Peterson, J.A.6
Horton, J.D.7
Garry, D.J.8
Bianco, A.C.9
Mangelsdorf, D.J.10
-
3
-
-
0013199471
-
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR α
-
Peet DJ, Turley SD, Ma W, Janowski BA, Lobaccaro JM, Hammer RE, Mangelsdorf DJ 1998 Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR α. Cell 93:693-704
-
(1998)
Cell
, vol.93
, pp. 693-704
-
-
Peet, D.J.1
Turley, S.D.2
Ma, W.3
Janowski, B.A.4
Lobaccaro, J.M.5
Hammer, R.E.6
Mangelsdorf, D.J.7
-
4
-
-
0035895202
-
LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes
-
Laffitte BA, Repa JJ, Joseph SB, Wilpitz DC, Kast HR, Mangelsdorf DJ, Tontonoz P 2001 LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes. Proc Natl Acad Sci USA 98:507- 512
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 507-512
-
-
Laffitte, B.A.1
Repa, J.J.2
Joseph, S.B.3
Wilpitz, D.C.4
Kast, H.R.5
Mangelsdorf, D.J.6
Tontonoz, P.7
-
5
-
-
33644865172
-
Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo
-
Naik SU, Wang X, Da Silva JS, Jaye M, Macphee CH, Reilly MP, Billheimer JT, Rothblat GH, Rader DJ 2006 Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo. Circulation 113:90-97
-
(2006)
Circulation
, vol.113
, pp. 90-97
-
-
Naik, S.U.1
Wang, X.2
Da Silva, J.S.3
Jaye, M.4
Macphee, C.H.5
Reilly, M.P.6
Billheimer, J.T.7
Rothblat, G.H.8
Rader, D.J.9
-
6
-
-
1842614391
-
Expression of the liver X receptor α and β in embryonic and adult mice. Anat Rec A Discov Mol Cell
-
Annicotte JS, SchoonjansK, Auwerx J 2004 Expression of the liver X receptor α and β in embryonic and adult mice. Anat Rec A Discov Mol Cell Evol Biol 277:312-316
-
(2004)
Evol Biol
, vol.277
, pp. 312-316
-
-
Annicotte, J.S.1
Schoonjans, K.2
Auwerx, J.3
-
7
-
-
0029805887
-
An oxysterol signalling pathway mediated by the nuclear receptor LXRα
-
Janowski BA, Willy PJ, Devi TR, Falck JR, Mangelsdorf DJ 1996 An oxysterol signalling pathway mediated by the nuclear receptor LXRα. Nature 383:728-731
-
(1996)
Nature
, vol.383
, pp. 728-731
-
-
Janowski, B.A.1
Willy, P.J.2
Devi, T.R.3
Falck, J.R.4
Mangelsdorf, D.J.5
-
8
-
-
0037046543
-
Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines
-
Collins JL, Fivush AM, Watson MA, Galardi CM, Lewis MC, Moore LB, Parks DJ, Wilson JG, Tippin TK, Binz JG, Plunket KD, Morgan DG, Beaudet EJ, Whitney KD, Kliewer SA, Willson TM 2002 Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines. J Med Chem 45:1963-1966
-
(2002)
J Med Chem
, vol.45
, pp. 1963-1966
-
-
Collins, J.L.1
Fivush, A.M.2
Watson, M.A.3
Galardi, C.M.4
Lewis, M.C.5
Moore, L.B.6
Parks, D.J.7
Wilson, J.G.8
Tippin, T.K.9
Binz, J.G.10
Plunket, K.D.11
Morgan, D.G.12
Beaudet, E.J.13
Whitney, K.D.14
Kliewer, S.A.15
Willson, T.M.16
-
9
-
-
0037503924
-
Liver X receptor signaling pathways in cardiovascular disease
-
Tontonoz P, Mangelsdorf DJ 2003 Liver X receptor signaling pathways in cardiovascular disease. Mol Endocrinol 17:985-993
-
(2003)
Mol Endocrinol
, vol.17
, pp. 985-993
-
-
Tontonoz, P.1
Mangelsdorf, D.J.2
-
10
-
-
0035047709
-
Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter
-
Yoshikawa T, Shimano H, Amemiya-Kudo M, Yahagi N, Hasty AH, Matsuzaka T, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, Kimura S, Ishibashi S, Yamada N 2001 Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter. Mol Cell Biol 21:2991-3000
-
(2001)
Mol Cell Biol
, vol.21
, pp. 2991-3000
-
-
Yoshikawa, T.1
Shimano, H.2
Amemiya-Kudo, M.3
Yahagi, N.4
Hasty, A.H.5
Matsuzaka, T.6
Okazaki, H.7
Tamura, Y.8
Iizuka, Y.9
Ohashi, K.10
Osuga, J.11
Harada, K.12
Gotoda, T.13
Kimura, S.14
Ishibashi, S.15
Yamada, N.16
-
11
-
-
0037192797
-
Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors
-
Joseph SB, Laffitte BA, Patel PH, Watson MA, Matsukuma KE, Walczak R, Collins JL, Osborne TF, Tontonoz P 2002 Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors. J Biol Chem 277:11019-11025
-
(2002)
J Biol Chem
, vol.277
, pp. 11019-11025
-
-
Joseph, S.B.1
Laffitte, B.A.2
Patel, P.H.3
Watson, M.A.4
Matsukuma, K.E.5
Walczak, R.6
Collins, J.L.7
Osborne, T.F.8
Tontonoz, P.9
-
12
-
-
33847006599
-
The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR
-
ChaJY,Repa JJ 2007 The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR. J Biol Chem 282:743-751
-
(2007)
J Biol Chem
, vol.282
, pp. 743-751
-
-
Cha, J.Y.1
Repa, J.J.2
-
13
-
-
0345098365
-
The LXR ligand T0901317 induces severe lipogenesis in the db/db diabetic mouse
-
Chisholm JW, Hong J, Mills SA, Lawn RM 2003 The LXR ligand T0901317 induces severe lipogenesis in the db/db diabetic mouse. J Lipid Res 44:2039- 2048
-
(2003)
J Lipid Res
, vol.44
, pp. 2039-2048
-
-
Chisholm, J.W.1
Hong, J.2
Mills, S.A.3
Lawn, R.M.4
-
14
-
-
34249682775
-
Chronic activation of liver X receptor induces β-cell apoptosis through hyperactivation of lipogenesis: Liver X receptor-mediated lipotoxicity in pancreatic β-cells
-
Choe SS, Choi AH, Lee JW, Kim KH, Chung JJ, Park J, Lee KM, Park KG, Lee IK, Kim JB 2007 Chronic activation of liver X receptor induces β-cell apoptosis through hyperactivation of lipogenesis: liver X receptor-mediated lipotoxicity in pancreatic β-cells. Diabetes 56:1534-1543
-
(2007)
Diabetes
, vol.56
, pp. 1534-1543
-
-
Choe, S.S.1
Choi, A.H.2
Lee, J.W.3
Kim, K.H.4
Chung, J.J.5
Park, J.6
Lee, K.M.7
Park, K.G.8
Lee, I.K.9
Kim, J.B.10
-
15
-
-
0033119162
-
Coactivator and corepressor complexes in nuclear receptor function
-
Xu L, Glass CK, Rosenfeld MG 1999 Coactivator and corepressor complexes in nuclear receptor function. Curr Opin Genet Dev 9:140-147
-
(1999)
Curr Opin Genet Dev
, vol.9
, pp. 140-147
-
-
Xu, L.1
Glass, C.K.2
Rosenfeld, M.G.3
-
16
-
-
0033525687
-
Competition between thyroid hormone receptor-associated protein (TRAP) 220 and transcriptional intermediary factor (TIF) 2 for binding to nuclear receptors. Implications for the recruitment of TRAP and p160 coactivator complexes
-
Treuter E, Johansson L, ThomsenJS, Warnmark A, Leers J, Pelto-Huikko M, Sjoberg M, Wright AP, Spyrou G, Gustafsson JA 1999 Competition between thyroid hormone receptor-associated protein (TRAP) 220 and transcriptional intermediary factor (TIF) 2 for binding to nuclear receptors. Implications for the recruitment of TRAP and p160 coactivator complexes. J Biol Chem 274: 6667-6677
-
(1999)
J Biol Chem
, vol.274
, pp. 6667-6677
-
-
Treuter, E.1
Johansson, L.2
Thomsen, J.S.3
Warnmark, A.4
Leers, J.5
Pelto-Huikko, M.6
Sjoberg, M.7
Wright, A.P.8
Spyrou, G.9
Gustafsson, J.A.10
-
17
-
-
0038517917
-
Liver X receptors interact with corepressors to regulate gene expression
-
Hu X, Li S, Wu J, Xia C, Lala DS 2003 Liver X receptors interact with corepressors to regulate gene expression. Mol Endocrinol 17:1019-1026
-
(2003)
Mol Endocrinol
, vol.17
, pp. 1019-1026
-
-
Hu, X.1
Li, S.2
Wu, J.3
Xia, C.4
Lala, D.S.5
-
18
-
-
0141737105
-
Crystal structure of the heterodimeric complex of LXRα and RXRβ ligand-binding domains in a fully agonistic conformation
-
Svensson S, Ostberg T, Jacobsson M, Norstrom C, Stefansson K, Hallen D, Johansson IC, ZachrissonK,OggD,Jendeberg L 2003 Crystal structure of the heterodimeric complex of LXRα and RXRβ ligand-binding domains in a fully agonistic conformation. EMBO J 22:4625-4633
-
(2003)
EMBO J
, vol.22
, pp. 4625-4633
-
-
Svensson, S.1
Ostberg, T.2
Jacobsson, M.3
Norstrom, C.4
Stefansson, K.5
Hallen, D.6
Johansson, I.C.7
Zachrisson, K.8
Ogg, D.9
Jendeberg, L.10
-
19
-
-
26444471700
-
A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ
-
Pascual G, Fong AL, Ogawa S, Gamliel A, Li AC, Perissi V, Rose DW, Willson TM, Rosenfeld MG, Glass CK 2005 A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ. Nature 437:759-763
-
(2005)
Nature
, vol.437
, pp. 759-763
-
-
Pascual, G.1
Fong, A.L.2
Ogawa, S.3
Gamliel, A.4
Li, A.C.5
Perissi, V.6
Rose, D.W.7
Willson, T.M.8
Rosenfeld, M.G.9
Glass, C.K.10
-
20
-
-
0242637101
-
Direct acetylation of the estrogen receptor α hinge region by p300 regulates transactivation and hormone sensitivity
-
Wang C, Fu M, Angeletti RH, Siconolfi-Baez L, Reutens AT, Albanese C, Lisanti MP, Katzenellenbogen BS, Kato S, Hopp T, Fuqua SA, Lopez GN, Kushner PJ, Pestell RG 2001 Direct acetylation of the estrogen receptor α hinge region by p300 regulates transactivation and hormone sensitivity. J Biol Chem 276:18375-18383
-
(2001)
J Biol Chem
, vol.276
, pp. 18375-18383
-
-
Wang, C.1
Fu, M.2
Angeletti, R.H.3
Siconolfi-Baez, L.4
Reutens, A.T.5
Albanese, C.6
Lisanti, M.P.7
Katzenellenbogen, B.S.8
Kato, S.9
Hopp, T.10
Fuqua, S.A.11
Lopez, G.N.12
Kushner, P.J.13
Pestell, R.G.14
-
21
-
-
10844286471
-
Phosphorylation of estrogen receptor α blocks its acetylation and regulates estrogen sensitivity
-
Cui Y, Zhang M, Pestell R, Curran EM, Welshons WV, Fuqua SA 2004 Phosphorylation of estrogen receptor α blocks its acetylation and regulates estrogen sensitivity. Cancer Res 64:9199-9208
-
(2004)
Cancer Res
, vol.64
, pp. 9199-9208
-
-
Cui, Y.1
Zhang, M.2
Pestell, R.3
Curran, E.M.4
Welshons, W.V.5
Fuqua, S.A.6
-
23
-
-
33745658056
-
Acetylation of estrogen receptor α by p300 at lysines 266 and 268 enhances the deoxyribonucleic acid binding and transactivation activities of the receptor
-
Kim MY, Woo EM, Chong YT, Homenko DR, Kraus WL 2006 Acetylation of estrogen receptor α by p300 at lysines 266 and 268 enhances the deoxyribonucleic acid binding and transactivation activities of the receptor. Mol Endocrinol 20:1479-1493
-
(2006)
Mol Endocrinol
, vol.20
, pp. 1479-1493
-
-
Kim, M.Y.1
Woo, E.M.2
Chong, Y.T.3
Homenko, D.R.4
Kraus, W.L.5
-
24
-
-
19944428232
-
Ligand-dependent switching of ubiquitin-proteasome pathways for estrogen receptor
-
Tateishi Y, Kawabe Y, Chiba T, Murata S, IchikawaK, Murayama A, Tanaka K, Baba T, Kato S, Yanagisawa J 2004 Ligand-dependent switching of ubiquitin-proteasome pathways for estrogen receptor. EMBO J 23:4813-4823
-
(2004)
EMBO J
, vol.23
, pp. 4813-4823
-
-
Tateishi, Y.1
Kawabe, Y.2
Chiba, T.3
Murata, S.4
Ichikawa, K.5
Murayama, A.6
Tanaka, K.7
Baba, T.8
Kato, S.9
Yanagisawa, J.10
-
25
-
-
8344241132
-
Inhibiting proteasomal proteolysis sustains estrogen receptor-a activation
-
Fan M, Nakshatri H, Nephew KP 2004 Inhibiting proteasomal proteolysis sustains estrogen receptor-a activation. Mol Endocrinol 18:2603-2615
-
(2004)
Mol Endocrinol
, vol.18
, pp. 2603-2615
-
-
Fan, M.1
Nakshatri, H.2
Nephew, K.P.3
-
27
-
-
34249721531
-
Protein kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver
-
Yamamoto T, Shimano H, Inoue N, Nakagawa Y, Matsuzaka T, Takahashi A, Yahagi N, Sone H, Suzuki H, Toyoshima H, Yamada N 2007 Protein kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver. J Biol Chem 282:11687- 11695
-
(2007)
J Biol Chem
, vol.282
, pp. 11687-11695
-
-
Yamamoto, T.1
Shimano, H.2
Inoue, N.3
Nakagawa, Y.4
Matsuzaka, T.5
Takahashi, A.6
Yahagi, N.7
Sone, H.8
Suzuki, H.9
Toyoshima, H.10
Yamada, N.11
-
28
-
-
33845970925
-
Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARγ
-
Ghisletti S, Huang W, Ogawa S, Pascual G, Lin ME, Willson TM, Rosenfeld MG, Glass CK 2007 Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARγ. Mol Cell 25: 57-70
-
(2007)
Mol Cell
, vol.25
, pp. 57-70
-
-
Ghisletti, S.1
Huang, W.2
Ogawa, S.3
Pascual, G.4
Lin, M.E.5
Willson, T.M.6
Rosenfeld, M.G.7
Glass, C.K.8
-
29
-
-
0037324340
-
Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
-
Joseph SB, Castrillo A, Laffitte BA, Mangelsdorf DJ, Tontonoz P 2003 Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nat Med 9:213-219
-
(2003)
Nat Med
, vol.9
, pp. 213-219
-
-
Joseph, S.B.1
Castrillo, A.2
Laffitte, B.A.3
Mangelsdorf, D.J.4
Tontonoz, P.5
-
30
-
-
0036467574
-
The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity
-
Baer R, Ludwig T 2002 The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity. Curr Opin Genet Dev 12:86-91
-
(2002)
Curr Opin Genet Dev
, vol.12
, pp. 86-91
-
-
Baer, R.1
Ludwig, T.2
-
31
-
-
0037684805
-
The multiple nuclear functions of BRCA1: Transcription, ubiquitination and DNA repair
-
Starita LM, Parvin JD 2003 The multiple nuclear functions of BRCA1: transcription, ubiquitination and DNA repair. Curr Opin Cell Biol 15:345-350
-
(2003)
Curr Opin Cell Biol
, vol.15
, pp. 345-350
-
-
Starita, L.M.1
Parvin, J.D.2
-
32
-
-
33845315093
-
Prevention of Brca1- mediated mammary tumorigenesis in mice by a progesterone antagonist
-
Poole AJ, Li Y, Kim Y, Lin SC, Lee WH, Lee EY 2006 Prevention of Brca1- mediated mammary tumorigenesis in mice by a progesterone antagonist. Science 314:1467-1470
-
(2006)
Science
, vol.314
, pp. 1467-1470
-
-
Poole, A.J.1
Li, Y.2
Kim, Y.3
Lin, S.C.4
Lee, W.H.5
Lee, E.Y.6
-
33
-
-
0029035278
-
LXR, a nuclear receptor that defines a distinct retinoid response pathway
-
Willy PJ, Umesono K, Ong ES, Evans RM, Heyman RA, Mangelsdorf DJ 1995 LXR, a nuclear receptor that defines a distinct retinoid response pathway. Genes Dev 9:1033-1045
-
(1995)
Genes Dev
, vol.9
, pp. 1033-1045
-
-
Willy, P.J.1
Umesono, K.2
Ong, E.S.3
Evans, R.M.4
Heyman, R.A.5
Mangelsdorf, D.J.6
-
34
-
-
19344376244
-
Tissue-specific autoregulation of the LXRα gene facilitates induction of apoE in mouse adipose tissue
-
Ulven SM, Dalen KT, Gustafsson JA, Nebb HI 2004 Tissue-specific autoregulation of the LXRα gene facilitates induction of apoE in mouse adipose tissue. J Lipid Res 45:2052-2062
-
(2004)
J Lipid Res
, vol.45
, pp. 2052-2062
-
-
Ulven, S.M.1
Dalen, K.T.2
Gustafsson, J.A.3
Nebb, H.I.4
-
35
-
-
0043133791
-
Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression
-
Wagner BL, Valledor AF, Shao G, Daige CL, Bischoff ED, Petrowski M, Jepsen K, Baek SH, Heyman RA, Rosenfeld MG, Schulman IG, Glass CK 2003 Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression. Mol Cell Biol 23:5780- 5789
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5780-5789
-
-
Wagner, B.L.1
Valledor, A.F.2
Shao, G.3
Daige, C.L.4
Bischoff, E.D.5
Petrowski, M.6
Jepsen, K.7
Baek, S.H.8
Heyman, R.A.9
Rosenfeld, M.G.10
Schulman, I.G.11
Glass, C.K.12
-
36
-
-
11144356074
-
Activated liver X receptors stimulate adipocyte differentiation through induction of peroxisome proliferator-activated receptor γ expression
-
Seo JB, Moon HM, Kim WS, Lee YS, Jeong HW, Yoo EJ, Ham J, Kang H, Park MG, Steffensen KR, Stulnig TM, Gustafsson JA, Park SD, Kim JB 2004 Activated liver X receptors stimulate adipocyte differentiation through induction of peroxisome proliferator-activated receptor γ expression. Mol Cell Biol 24:3430-3444
-
(2004)
Mol Cell Biol
, vol.24
, pp. 3430-3444
-
-
Seo, J.B.1
Moon, H.M.2
Kim, W.S.3
Lee, Y.S.4
Jeong, H.W.5
Yoo, E.J.6
Ham, J.7
Kang, H.8
Park, M.G.9
Steffensen, K.R.10
Stulnig, T.M.11
Gustafsson, J.A.12
Park, S.D.13
Kim, J.B.14
-
37
-
-
0031431599
-
Androgen responsive adult human prostatic epithelial cell lines immortalized by human papillomavirus 18
-
Bello D, Webber MM, Kleinman HK, Wartinger DD, Rhim JS 1997 Androgen responsive adult human prostatic epithelial cell lines immortalized by human papillomavirus 18. Carcinogenesis 18:1215-1223
-
(1997)
Carcinogenesis
, vol.18
, pp. 1215-1223
-
-
Bello, D.1
Webber, M.M.2
Kleinman, H.K.3
Wartinger, D.D.4
Rhim, J.S.5
-
38
-
-
34249696521
-
Block of nuclear receptor ubiquitination. A mechanism of ligand-dependent control of peroxisome proliferator-activated receptor δ activity
-
Genini D, Catapano CV 2007 Block of nuclear receptor ubiquitination. A mechanism of ligand-dependent control of peroxisome proliferator-activated receptor δ activity. J Biol Chem 282:11776-11785
-
(2007)
J Biol Chem
, vol.282
, pp. 11776-11785
-
-
Genini, D.1
Catapano, C.V.2
-
39
-
-
0033304612
-
1,25-Dihydroxyvitamin D3 increases nuclear vitamin D3 receptors by blocking ubiquitin/proteasome-mediated degradation in human skin
-
Li XY, Boudjelal M, XiaoJH, Peng ZH, Asuru A, Kang S, Fisher GJ, Voorhees JJ 1999 1,25-Dihydroxyvitamin D3 increases nuclear vitamin D3 receptors by blocking ubiquitin/proteasome-mediated degradation in human skin. Mol Endocrinol 13:1686-1694
-
(1999)
Mol Endocrinol
, vol.13
, pp. 1686-1694
-
-
Li, X.Y.1
Boudjelal, M.2
Xiao, J.H.3
Peng, Z.H.4
Asuru, A.5
Kang, S.6
Fisher, G.J.7
Voorhees, J.J.8
-
40
-
-
0037020156
-
Peroxisome proliferator-activated receptor α (PPARα) turnover by the ubiquitin-proteasome system controls the ligand-induced expression level of its target genes
-
Blanquart C, Barbier O, Fruchart JC, Staels B, Glineur C 2002 Peroxisome proliferator-activated receptor α (PPARα) turnover by the ubiquitin-proteasome system controls the ligand-induced expression level of its target genes. J Biol Chem 277:37254-37259
-
(2002)
J Biol Chem
, vol.277
, pp. 37254-37259
-
-
Blanquart, C.1
Barbier, O.2
Fruchart, J.C.3
Staels, B.4
Glineur, C.5
-
41
-
-
0033514930
-
Proteasome-dependent degradation of the human estrogen receptor
-
Nawaz Z, Lonard DM, Dennis AP, Smith CL, O'Malley BW 1999 Proteasome-dependent degradation of the human estrogen receptor. Proc Natl Acad Sci USA 96:1858-1862
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 1858-1862
-
-
Nawaz, Z.1
Lonard, D.M.2
Dennis, A.P.3
Smith, C.L.4
O'Malley, B.W.5
-
42
-
-
0035900780
-
Proteasome-mediated glucocorticoid receptor degradation restricts transcriptional signaling by glucocorticoids
-
Wallace AD, Cidlowski JA 2001 Proteasome-mediated glucocorticoid receptor degradation restricts transcriptional signaling by glucocorticoids. J Biol Chem 276:42714-42721
-
(2001)
J Biol Chem
, vol.276
, pp. 42714-42721
-
-
Wallace, A.D.1
Cidlowski, J.A.2
-
43
-
-
0034674567
-
Degradation of the peroxisome proliferator-activated receptor 7 is linked to ligand-dependent activation
-
Hauser S, Adelmant G, Sarraf P, Wright HM, Mueller E, Spiegelman BM 2000 Degradation of the peroxisome proliferator-activated receptor 7 is linked to ligand-dependent activation. J Biol Chem 275:18527-18533
-
(2000)
J Biol Chem
, vol.275
, pp. 18527-18533
-
-
Hauser, S.1
Adelmant, G.2
Sarraf, P.3
Wright, H.M.4
Mueller, E.5
Spiegelman, B.M.6
-
44
-
-
2642528530
-
Different ways to regulate the PPARα stability
-
Blanquart C, Mansouri R, Fruchart JC, Staels B, Glineur C 2004 Different ways to regulate the PPARα stability. Biochem Biophys Res Commun 319: 663-670
-
(2004)
Biochem Biophys Res Commun
, vol.319
, pp. 663-670
-
-
Blanquart, C.1
Mansouri, R.2
Fruchart, J.C.3
Staels, B.4
Glineur, C.5
-
46
-
-
0034002793
-
Fatty-acid synthase and human cancer: New perspectives on its role in tumor biology
-
Kuhajda FP 2000 Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology. Nutrition 16:202-208
-
(2000)
Nutrition
, vol.16
, pp. 202-208
-
-
Kuhajda, F.P.1
-
47
-
-
0034697973
-
BRCA1 is associated with a human SWI/SNF-related complex: Linking chromatin remodeling to breast cancer
-
Bochar DA, Wang L, Beniya H, Kinev A, Xue Y, Lane WS, Wang W, Kashanchi F, Shiekhattar R 2000 BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer. Cell 102:257-265
-
(2000)
Cell
, vol.102
, pp. 257-265
-
-
Bochar, D.A.1
Wang, L.2
Beniya, H.3
Kinev, A.4
Xue, Y.5
Lane, W.S.6
Wang, W.7
Kashanchi, F.8
Shiekhattar, R.9
-
48
-
-
18844407814
-
BRCA1/BARD1 inhibition of mRNA 3' processing involves targeted degradation of RNA polymerase II
-
Kleiman FE, Wu-Baer F, Fonseca D, Kaneko S, Baer R, Manley JL 2005 BRCA1/BARD1 inhibition of mRNA 3' processing involves targeted degradation of RNA polymerase II. Genes Dev 19:1227-1237
-
(2005)
Genes Dev
, vol.19
, pp. 1227-1237
-
-
Kleiman, F.E.1
Wu-Baer, F.2
Fonseca, D.3
Kaneko, S.4
Baer, R.5
Manley, J.L.6
-
49
-
-
0037122004
-
Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains
-
Mallery DL, Vandenberg CJ, Hiom K 2002 Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains. EMBO J 21: 6755-6762
-
(2002)
EMBO J
, vol.21
, pp. 6755-6762
-
-
Mallery, D.L.1
Vandenberg, C.J.2
Hiom, K.3
-
50
-
-
0033609057
-
BRCA1 interacts with components of the histone deacetylase complex
-
Yarden RI, Brody LC 1999 BRCA1 interacts with components of the histone deacetylase complex. Proc Natl Acad Sci USA 96:4983-4988
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 4983-4988
-
-
Yarden, R.I.1
Brody, L.C.2
-
51
-
-
34948883324
-
SIRT1 deacetylates and positively regulates the nuclear receptor LXR
-
Li X, Zhang S, Blander G, Tse JG, Krieger M, Guarente L 2007 SIRT1 deacetylates and positively regulates the nuclear receptor LXR. Mol Cell 28:91-106
-
(2007)
Mol Cell
, vol.28
, pp. 91-106
-
-
Li, X.1
Zhang, S.2
Blander, G.3
Tse, J.G.4
Krieger, M.5
Guarente, L.6
-
52
-
-
33748423356
-
Selective LXRα inhibitory effects observed in plant extracts of MEH184 (Parthenocissua tricuspidata) and MEH185 (Euscaphis japonica)
-
Kim KH, Choi SH, Lee TS, Oh WK, Kim DS, Kim JB 2006 Selective LXRα inhibitory effects observed in plant extracts of MEH184 (Parthenocissua tricuspidata) and MEH185 (Euscaphis japonica). Biochem Biophys Res Commun 349:513-518
-
(2006)
Biochem Biophys Res Commun
, vol.349
, pp. 513-518
-
-
Kim, K.H.1
Choi, S.H.2
Lee, T.S.3
Oh, W.K.4
Kim, D.S.5
Kim, J.B.6
|