The LXR ligand T0901317 induces severe lipogenesis in the db/db diabetic mouse

Journal of Lipid Research

Volumn 44, Issue 11, 2003, Pages 2039-2048

  Chisholm, Jeffrey W ^a   Hong, Jenny ^a   Mills, Scott A ^a   Lawn, Richard M ^a  

^a CV THERAPEUTICS INC   (United States)

Author keywords

Atherosclerosis; ATP binding cassette transporter A1; Db db; Diabetes; Leptin receptor; Liver X receptor; Triacylglycerols; Triglycerides; Very low density lipoprotein

Indexed keywords

ABC TRANSPORTER; FAS LIGAND; FATTY ACID SYNTHASE; HIGH DENSITY LIPOPROTEIN; HYPOCHOLESTEROLEMIC AGENT; INSULIN; LEPTIN; LIVER X RECEPTOR LIGAND; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); STEROL REGULATORY ELEMENT BINDING PROTEIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFECT; DRUG MECHANISM; GENE EXPRESSION; GENE TARGETING; GLUCONEOGENESIS; HYPERINSULINEMIA; HYPERTRIGLYCERIDEMIA; LIPOGENESIS; MALE; MOUSE STRAIN; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; TANGIER DISEASE; TRIACYLGLYCEROL BLOOD LEVEL; UPREGULATION;

ANIMALS; ANTICHOLESTEREMIC AGENTS; BODY WEIGHT; CHOLESTEROL; DIABETES MELLITUS; DISEASE MODELS, ANIMAL; INSULIN; LIGANDS; LIPIDS; LIPOPROTEINS; LIVER; MALE; MICE; MICE, TRANSGENIC; ORGAN SIZE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SULFONAMIDES; TRIGLYCERIDES;

EID: 0345098365     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: 10.1194/jlr.M300135-JLR200     Document Type: Article

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