Saponins as tool for improved targeted tumor therapies

Current Drug Targets

Volumn 10, Issue 2, 2009, Pages 140-151

  Fuchs, Hendrik ^a   Bachran, D ^a   Panjideh, H ^a   Schellmann, N ^a   Weng, A ^b   Melzig, M F ^b   Sutherland, M ^c   Bachran, C ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c UNIVERSITY OF BRADFORD   (United Kingdom)

Author keywords

Cancer; Chimeric toxins; Cleavable adapters; Epidermal growth factor receptor; Glycosylated triterpenoids; Ribosome inactivating proteins; Saponins; Targeted tumor therapy

Indexed keywords

AVICIN D; AVICIN G; CELL PENETRATING PEPTIDE; CISPLATIN; CYCLIN DEPENDENT KINASE 2 INHIBITOR; CYCLOPHOSPHAMIDE; DIOSCIN; DIPHTHERIA TOXIN; GINSENOSIDE RB 1; GINSENOSIDE RD; GINSENOSIDE RE; GINSENOSIDE RH 2; JULIBROSIDE; PACLITAXEL; PENETRATIN; PEPTIDE DERIVATIVE; PROTEIN TRANSDUCTION DOMAIN; QUIL A; RIBOSOME INACTIVATING PROTEIN 1; SAIKOSAPONIN; SAIKOSAPONIN A; SAIKOSAPONIN D; SAPONIN; SAPONIN DERIVATIVE; SOYASAPONIN I; TRANSACTIVATOR PROTEIN; TRITERPENOID; TROJAN PEPTIDE; TUBEIMOSIDE 1; UNCLASSIFIED DRUG; UNINDEXED DRUG; ANTINEOPLASTIC AGENT;

ANTIFUNGAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; APOPTOSIS; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER SURVIVAL; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CLINICAL TRIAL; DRUG EFFICACY; DRUG ISOLATION; DRUG POTENTIATION; DRUG PURIFICATION; DRUG TARGETING; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; IC 50; LEUKEMIA; MALIGNANT NEOPLASTIC DISEASE; NONHUMAN; PAPILLOMA; POLYGONATUM; POLYGONATUM ZANLANSCIANENSE; REVIEW; SKIN TUMOR; SMILACINA; SMILACINA ATROPURPUREA; DRUG DELIVERY SYSTEM; NEOPLASM;

ANTINEOPLASTIC AGENTS; DRUG DELIVERY SYSTEMS; HUMANS; NEOPLASMS; SAPONINS;

EID: 64249172406     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/138945009787354584     Document Type: Review

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