Antiviral, haemolytic and molluscicidal activities of triterpenoid saponins from Maesa lanceolata: Establishment of structure-activity relationships

Planta Medica

Volumn 67, Issue 6, 2001, Pages 528-532

  Apers, S ^a   Baronikova, S ^a   Sindambiwe, J B ^a   Witvrouw, M ^b   De Clercq, E ^b   Vanden Berghe, D ^a   Van Marck, E ^a   Vlietinck, A ^a   Pieters, L ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Antiviral activity; Haemolytic activity; Maesa lanceolata; Molluscicidal activity; Saponin esters; Triterpenoid saponins

Indexed keywords

3BETA O [[ALPHA LEVO RHAMNOPYRANOSYL(1-2) BETA DEXTRO GALACTOPYRANOSYL(1-3)][BETA DEXTRO GALACTOPYRANOSYL(1-2)] BETA DEXTRO GLUCOPYRANURONYL] 21BETA,22ALPHA DIANGELOYLOXY 13BETA,28 EPOXYOLEAN 16ALPHA,28ALPHA DIOL; MAESA LANCEOLATA EXTRACT; MAESASAPONIN VI 2; PLANT EXTRACT; SAPONIN DERIVATIVE; TRITERPENOID; UNCLASSIFIED DRUG;

ACYLATION; ANTIVIRAL ACTIVITY; ARTICLE; DRUG ACTIVITY; DRUG ISOLATION; DRUG SCREENING; HEMOLYSIS; NONHUMAN; PLANT LEAF; STRUCTURE ACTIVITY RELATION;

ANGIOSPERMS; ANIMALS; ANTI-HIV AGENTS; ANTIVIRAL AGENTS; CARBOHYDRATE SEQUENCE; HEMOLYSIS; HERPESVIRUS 1, HUMAN; HIV; HUMANS; MEDICINE, AFRICAN TRADITIONAL; MOLECULAR SEQUENCE DATA; MOLLUSCACIDES; PHYTOTHERAPY; PLANT EXTRACTS; PLANTS, MEDICINAL; SAPONINS; SNAILS; STRUCTURE-ACTIVITY RELATIONSHIP; TREES; TRITERPENES;

LANCEOLATA; MAESA; MAESA LANCEOLATA;

EID: 0034861504     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2001-16489     Document Type: Article

References (16)

1. Triterpenoid saponins from Maesa lanceolata
2. Evaluation of biological activities of triterpenoid saponins from Maesa lanceolata
3. Separation of a triterpenoid saponin mixture from Maesa lanceolata: Semipreparative reversed-phase wide pore high performance liquid chromatography with temperature control
4. New acylated triterpenoid saponins from Maesa lanceolata
5. Antiviral agents from higher plants and an example of structure-activity relationship of 3-methoxyflavones
6. The monomesylates of 1-(2′-deoxy-β-D-lyxofuranosyl) thymine
7. The glomerulopathy associated with Schistosoma mansoni infection. An experimental study in the mouse
8. Preliminary studies of antiviral activity of triterpenoid saponins: Relationships between their chemical structure and antiviral activity
9. The effects of saikosaponins on biological membranes. 1. The relationship between the structures of saikosaponins and haemolytic activity
10. Schistosomiasis
11. Search for antifungal, molluscicidal and larvicidal compounds from African medicinal plants
12. Saponins
13. A semi-quantitative approach to the selection of appropriate candidate plant molluscicides - A South African application