Avicins, natural anticancer saponins, permeabilize mitochondrial membranes

Archives of Biochemistry and Biophysics

Volumn 454, Issue 2, 2006, Pages 114-122

  Lemeshko, Victor V ^a   Haridas, Valsala ^b   Quijano Pérez, Jairo C ^a   Gutterman, Jordan U ^b  

^a UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Apoptosis; Avicin; Cancer; Cytochrome c; Hydroperoxides; Mitochondria; NADPH; Outer mitochondrial membrane

Indexed keywords

ANTINEOPLASTIC AGENT; AVICIN; CYCLOSPORIN A; CYTOCHROME C; HYDROPEROXIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; ROTENONE; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LIVER MITOCHONDRION; MALE; MEMBRANE PERMEABILITY; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION SWELLING; NONHUMAN; OUTER MEMBRANE; OXIDATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE; TUMOR CELL;

ANIMALS; ANTINEOPLASTIC AGENTS; CYCLOSPORINE; CYTOCHROMES C; HYDROGEN PEROXIDE; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA, LIVER; MITOCHONDRIAL MEMBRANES; MITOCHONDRIAL SWELLING; NAD; NADP; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PERMEABILITY; RATS; RATS, SPRAGUE-DAWLEY; ROTENONE; SAPONINS;

EID: 33749647651     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2006.08.008     Document Type: Article

References (62)

1. Haridas V., Higuchi M., Jayatilake G.S., Bailey D., Mujoo K., Blake M.E., Arntzen C.J., and Gutterman J.U. Proc. Natl. Acad. Sci. USA 98 (2001) 5821-5826
2. Mujoo K., Haridas V., Hoffmann J.J., Wachter G.A., Hutter L.K., Lu Y., Blake M.E., Jayatilake G.S., Bailey D., Mills G.B., and Gutterman J.U. Cancer Res. 61 (2001) 5486-5490
3. Gaikwad A., Poblenz A., Haridas V., Zhang C., Duvic M., and Gutterman J.U. Clin. Cancer Res. 11 (2005) 1953-1962
4. N. Mitsiades, C.J. McMullan, V. Poulaki, J., Negri, J. Gutterman, K.C. Anderson, C.S. Mitsiades, Blood 104 (2004) abstract #2403.
5. Gutterman J.U., Lai H.T., Yang P., Haridas V., Gaikwad A., and Marcus S. Proc. Natl. Acad. Sci. USA 102 (2005) 12771-12776
6. Hanausek M., Ganesh P., Walaszek Z., Arntzen C.J., Slaga T.J., and Gutterman J.U. Proc. Natl. Acad. Sci. USA 98 (2001) 11551-11556
7. Haridas V., Arntzen C.J., and Gutterman J.U. Proc. Natl. Acad. Sci. USA 98 (2001) 11557-11562
8. Haridas V., Hanausek M., Nishimura G., Soehnge H., Gaikwad A., Narog M., Spears E., Zoltaszek R., Walaszek Z., and Gutterman J.U. J. Clin. Invest. 113 (2004) 65-73
9. Haridas V., Kim S.-O., Nishimura G., Hausladen A., Stamler J.S., and Gutterman J.U. Proc. Natl. Acad. Sci. USA 102 (2005) 10088-10093
10. Blackstone N.W., Kelly M.M., Haridas V., and Gutterman J.U. Proc. R. Soc. Lond. B. Biol. Sci. 272 (2005) 527-531
11. Dias N., and Bailly C. Biochem. Pharmacol. 70 (2005) 1-12
12. Armstrong J.S. Br. J. Pharmacol. 147 (2006) 239-248
13. Rostovtseva T.K., Tan W., and Colombini M. J. Bioenerg. Biomembr. 37 (2005) 129-142
14. Lemasters J.J., and Holmuhamedov E. Biochim. Biophys. Acta 1762 (2006) 119-181
15. Bouchier-Hayes L., Lartigue L., and Newmeyer D. J. Clin. Invest. 115 (2005) 2640-2647
16. Kowaltowski A.J., Castilho R.F., and Vercesi A.E. FEBS Lett. 495 (2001) 12-15
17. Rigobello M.P., Folda A., Scutari G., and Bindoli A. Arch. Biochem. Biophys. 441 (2005) 112-122
18. Szatrowski T.P., and Nathan C.F. Cancer Res. 51 (1991) 794-798
19. Gupta A., Rosenberger S.F., and Bowden G.T. Carcinogenesis 20 (1999) 2063-2073
20. Schoene N.W., and Kamara K.S. Free Radic. Biol. Med. 27 (1999) 364-369
21. Jackson A.L., and Loeb L.A. Mutat Res. 477 (2001) 7-21
22. Laurent A., Nicco C., Chereau C., Goulvestre C., Alexandre J., Alves A., Levy E., Goldwasser F., Panis Y., Soubrane O., Weill B., and Batteux F. Cancer Res. 65 (2005) 948-956
23. Jayatilake G.S., Freeberg D.R., Liu Z., Richheimer S.L., Blake M.E., NietoBailey D.T., Haridas V., and Gutterman J.U. J. Nat. Prod. 66 (2003) 779-783
24. Schneider W.C., and Hogeboom G.H. J. Biol. Chem. 183 (1950) 123-128
25. Lemeshko V.V. J. Biol. Chem. 277 (2002) 17751-17757
26. Lemeshko V.V. Arch. Biochem. Biophys. 388 (2001) 60-66
27. Lemeshko V.V. Biochem. Biophys. Res. Commun. 291 (2002) 170-175
28. Lemeshko V.V., Arias M., and Orduz S. J. Biol. Chem. 280 (2005) 15579-15586
29. Facundo H.T., Fornazari M., and Kowaltowski A.J. Biochim. Biophys. Acta 1762 (2006) 202-212
30. Castilho R.F., Kowaltowski A.J., Meinicke A.R., Bechara E.J., and Vercesi A.E. Free Radic. Biol. Med. 18 (1995) 479-486
31. Gunter T.E., and Pfeiffer D.R. Am. J. Physiol. 258 (1990) C755-C786
32. Nieminen A.-L., Byrne A.M., Herman B., and Lemasters J.J. Am. J. Physiol. 272 (1997) C1286-C1294
33. Byrne A.M., Lemasters J.J., and Nieminen A.L. Hepatology 29 (1999) 1523-1531
34. Kowaltowski A.J., Netto L.E., and Vercesi A.E. J. Biol. Chem. 273 (1998) 12766-12769
35. Griffin J.L., and Shocker J.P. Nat. Rev. Cancer 4 (2004) 551-561
36. Ramanathan A., Wang C., and Schreiber S.L. Proc. Natl. Acad. Sci. USA 102 (2005) 5992-5997
37. Zamzami N., and Kroemer G. Nat. Rev. Mol. Cell. Biol. 2 (2001) 67-71
38. Brumatti G., Weinlich R., Chehab C.F., Yon M., and Amarante-Mendes G.P. FEBS Lett. 541 (2003) 57-63
39. Don A.S., and Hogg P.J. Trends Mol. Med. 10 (2004) 372-378
40. Appaix F., Guerrero K., Rampal D., Izikki M., Kaambre T., Sikk P., Brdiczka D., Riva-Lavieille C., Olivares J., Longuet M., Antonsson B., and Saks V.A. Biochim. Biophys. Acta 1556 (2002) 155-167
41. Skulachev V.P. FEBS Lett. 423 (1998) 275-280
42. Pan Z., Voehringer D.W., and Meyn R.E. Cell Death Differ. 6 (1999) 683-688
43. Bernardi P., and Azzone G.F. J. Biol. Chem. 256 (1981) 7187-7192
44. Hochachka P.W., Rupert J.L., Goldenberg L., Gleave M., and Kozlowski P. BioEssays 24 (2002) 749-757
45. Schnaitman C., and Greenawalt J.W. J. Cell. Biol. 38 (1968) 158-175
46. Li X.X., Davis B., Haridas V., Gutterman J.U., and Colombini M. Biophys. J. 88 (2005) 2577-2584
47. Dourmashkin R.R., Dougherty R.M., and Harris R.J. Nature 194 (1962) 1116-1119
48. Bangham A.D., Horne R.W., Glauert A.M., Dingle J.T., and Lucy J.A. Nature 196 (1962) 952-955
49. Antonsson B., Montessuit S., Sanchez B., and Martinou J.-C. J. Biol. Chem. 276 (2001) 11615-11623
50. Grinberg M., Sarig R., Zaltsman Y., Frumkin D., Grammatikakis N., Reuveny E., and Gross A. J. Biol. Chem. 277 (2002) 12237-12245
51. Mikhailov V., Mikhailova M., Degenhardt K., Venkatachalam M.A., White E., and Saikumar P. J. Biol. Chem. 278 (2003) 5367-5376
52. Yi X., Yin X.-M., and Dong Z. J. Biol. Chem. 278 (2003) 16992-16999
53. Annis M.G., Soucie E.L., Dlugosz P.J., Cruz-Aguado J.A., Penn L.Z., Leber B., and Andrews D.W. EMBO J. 24 (2005) 2096-2103
54. Yethon J.A., Epand R.F., Leber B., Epand R.M., and Andrews D.W. J. Biol. Chem. 278 (2003) 48935-48941
55. Yamaji-Hasegawa A., Makino A., Baba T., Senoh Y., Kimura-Suda H., Sato S.B., Terada N., Ohno S., Kiyokawa E., Umeda M., and Kobayashi T. J. Biol. Chem. 278 (2003) 22762-22770
56. Crompton M. Biochem. J. 341 (1999) 233-249
57. Chernyak B.V., and Bernardi P. Eur. J. Biochem. 238 (1996) 623-630
58. McStay G.P., Clarke S.J., and Halestrap A.P. Biochem. J. 367 Pt 2 (2002) 541-548
59. Petit P.X., Gendron M.C., Schrantz N., Metivier D., Kroemer G., Maciorowska Z., Sureau F., and Koester S. Biochem. J. 353 (2001) 357-367
60. Zhou L., Jing Y., Styblo M., Chen Z., and Waxman S. Blood 105 (2005) 1198-1203
61. Giorgio M., Migliaccio E., Orsini F., Paolucci D., Moroni M., Contursi C., Pelliccia G., Luzi L., Minucci S., Marcaccio M., Pinton P., Rizzuto R., Bernardi P., Paolucci F., and Pelicci P.G. Cell 122 (2005) 221-233
62. Bernardi P., Petronilli V., Di Lisa F., and Forte M. Trends Biochem. Sci. 26 (2001) 112-117