Chapter 5 Applying the Genetics of Secondary Metabolism in Model Actinomycetes to the Discovery of New Antibiotics

Methods in Enzymology

Volumn 458, Issue A, 2009, Pages 117-141

  van Wezel, Gilles P ^a   McKenzie, Nancy L ^b   Nodwell, Justin R ^b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTINORHODINE; ANTIBIOTIC AGENT; BLASTICIDIN S; CALCIUM DEPENDENT ANTIBIOTIC; CHLORAMPHENICOL; CLAVULANIC ACID; DACTINOMYCIN; DAPTOMYCIN; ERYTHROMYCIN; METHYLENOMYCIN; NATURAL PRODUCT; NOVOBIOCIN; PHOSPHATE; STREPTOMYCIN; TEICOPLANIN; UNCLASSIFIED DRUG; UNDECYLPRODIGIOSIN; VALANIMYCIN;

ACTINOBACTERIA; ALLELE; ANTIBIOTIC BIOSYNTHESIS; ANTIMICROBIAL ACTIVITY; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIAL STRAIN; BACTERIUM CULTURE; BACTERIUM ISOLATE; CELL METABOLISM; DNA BINDING; DRUG MANUFACTURE; DRUG SCREENING; GENE CLUSTER; GENETIC ENGINEERING; GENETIC MANIPULATION; GENETIC REGULATION; HETEROLOGOUS EXPRESSION; METABOLITE; MOLECULAR GENETICS; MOLECULAR INTERACTION; MORPHOLOGY; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PLEIOTROPY; PRIORITY JOURNAL; PROKARYOTE; PROMOTER REGION; REGULATORY MECHANISM; REGULON; REVIEW; SILENT GENE; STREPTOMYCES; STREPTOMYCES COELICOLOR; STREPTOMYCETACEAE; TRANSCRIPTION REGULATION;

ACTINOBACTERIA; ANTI-BACTERIAL AGENTS; DRUG EVALUATION, PRECLINICAL; GENE EXPRESSION REGULATION, BACTERIAL; GENETIC TECHNIQUES;

ACTINOBACTERIA (CLASS); STREPTOMYCES; STREPTOMYCINEAE;

EID: 64249163186     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0076-6879(09)04805-8     Document Type: Review

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