-
2
-
-
0342905433
-
Risks of leukaemia and solid tumours in individuals with Down's syndrome
-
Hasle H, Clemmensen IH, Mikkelsen M. Risks of leukaemia and solid tumours in individuals with Down's syndrome. Lancet 2000;355:165-169.
-
(2000)
Lancet
, vol.355
, pp. 165-169
-
-
Hasle, H.1
Clemmensen, I.H.2
Mikkelsen, M.3
-
3
-
-
33644872564
-
Cancer incidence of persons with Down syndrome in Finland: A population-based study
-
Patja K, Pukkala E, Sund R et al. Cancer incidence of persons with Down syndrome in Finland: A population-based study. Int J Cancer 2006;118: 1769-1772.
-
(2006)
Int J Cancer
, vol.118
, pp. 1769-1772
-
-
Patja, K.1
Pukkala, E.2
Sund, R.3
-
4
-
-
0037160991
-
Mortality associated with Down's syndrome in the USA from 1983 to 1997: A population-based study
-
Yang Q, Rasmussen SA, Friedman JM. Mortality associated with Down's syndrome in the USA from 1983 to 1997: A population-based study. Lancet 2002;359:1019-1025.
-
(2002)
Lancet
, vol.359
, pp. 1019-1025
-
-
Yang, Q.1
Rasmussen, S.A.2
Friedman, J.M.3
-
5
-
-
0001430504
-
Acute lymphatic leukemia: Report of a case in eleventh month mongolian idiot
-
Brewster HF, Cannon HE. Acute lymphatic leukemia: Report of a case in eleventh month mongolian idiot. New Orleans Med Surg J 1930;82:872-873.
-
(1930)
New Orleans Med Surg J
, vol.82
, pp. 872-873
-
-
Brewster, H.F.1
Cannon, H.E.2
-
6
-
-
0000638625
-
Simultaneous occurrence of mongolism and leukemia; report of a nationwide survey
-
Krivit W, Good RA. Simultaneous occurrence of mongolism and leukemia; report of a nationwide survey. AMA J Dis Child 1957;94:289-293.
-
(1957)
AMA J Dis Child
, vol.94
, pp. 289-293
-
-
Krivit, W.1
Good, R.A.2
-
7
-
-
0142089730
-
Increased age at diagnosis has a significantly negative effect on outcome in children with Down syndrome and acute myeloid leukemia: A report from the Children's Cancer Group Study 2891
-
Gamis AS, Woods WG, Alonzo TA et al. Increased age at diagnosis has a significantly negative effect on outcome in children with Down syndrome and acute myeloid leukemia: A report from the Children's Cancer Group Study 2891. J Clin Oncol 2003;21:3415-3422.
-
(2003)
J Clin Oncol
, vol.21
, pp. 3415-3422
-
-
Gamis, A.S.1
Woods, W.G.2
Alonzo, T.A.3
-
8
-
-
35648968664
-
Acute megakaryoblastic leukemia in Down syndrome
-
Hitzler JK. Acute megakaryoblastic leukemia in Down syndrome. Pediatr Blood Cancer 2007;49(7 suppl):1066-1069.
-
(2007)
Pediatr Blood Cancer
, vol.49
, Issue.7 SUPPL.
, pp. 1066-1069
-
-
Hitzler, J.K.1
-
9
-
-
18944404989
-
AML patients with Down syndrome have a high cure rate with AML-BFM therapy with reduced dose intensity
-
Creutzig U, Reinhardt D, Diekamp S et al. AML patients with Down syndrome have a high cure rate with AML-BFM therapy with reduced dose intensity. Leukemia 2005;19:1355-1360.
-
(2005)
Leukemia
, vol.19
, pp. 1355-1360
-
-
Creutzig, U.1
Reinhardt, D.2
Diekamp, S.3
-
10
-
-
0028213440
-
Myelodysplasia and acute megakaryoblastic leukemia in Down's syndrome
-
Zipursky A, Thorner P, De Harven E et al. Myelodysplasia and acute megakaryoblastic leukemia in Down's syndrome. Leuk Res 1994;18:163-171.
-
(1994)
Leuk Res
, vol.18
, pp. 163-171
-
-
Zipursky, A.1
Thorner, P.2
De Harven, E.3
-
11
-
-
17144444346
-
Environmental factors contributing to the development of childhood leukemia in children with Down's syndrome
-
Mejia-Arangure JM, Fajardo-Gutierrez A, Flores-Aguilar H et al. Environmental factors contributing to the development of childhood leukemia in children with Down's syndrome. Leukemia 2003;17:1905-1907.
-
(2003)
Leukemia
, vol.17
, pp. 1905-1907
-
-
Mejia-Arangure, J.M.1
Fajardo-Gutierrez, A.2
Flores-Aguilar, H.3
-
12
-
-
33747889357
-
Child and maternal household chemical exposure and the risk of acute leukemia in children with Down's syndrome: A report from the Children's Oncology Group
-
Alderton LE, Spector LG, Blair CK et al. Child and maternal household chemical exposure and the risk of acute leukemia in children with Down's syndrome: A report from the Children's Oncology Group. Am J Epidemiol 2006;164:212-221.
-
(2006)
Am J Epidemiol
, vol.164
, pp. 212-221
-
-
Alderton, L.E.1
Spector, L.G.2
Blair, C.K.3
-
14
-
-
35649002050
-
Reproductive history, infertility treatment, and the risk of acute leukemia in children with Down syndrome: A report from the Children's Oncology Group
-
Puumala SE, Ross JA, Olshan AF et al. Reproductive history, infertility treatment, and the risk of acute leukemia in children with Down syndrome: A report from the Children's Oncology Group. Cancer 2007;110:2067-2074.
-
(2007)
Cancer
, vol.110
, pp. 2067-2074
-
-
Puumala, S.E.1
Ross, J.A.2
Olshan, A.F.3
-
15
-
-
22244448021
-
Periconceptional vitamin use and leukemia risk in children with Down syndrome: A Children's Oncology Group study
-
Ross JA, Blair CK, Olshan AF et al. Periconceptional vitamin use and leukemia risk in children with Down syndrome: A Children's Oncology Group study. Cancer 2005;104:405-410.
-
(2005)
Cancer
, vol.104
, pp. 405-410
-
-
Ross, J.A.1
Blair, C.K.2
Olshan, A.F.3
-
16
-
-
42249101930
-
Vitamin supplement use among children with Down's syndrome and risk of leukaemia: A Children's Oncology Group (COG) study
-
Blair CK, Roesler M, Xie Y et al. Vitamin supplement use among children with Down's syndrome and risk of leukaemia: A Children's Oncology Group (COG) study. Paediatr PerinatEpidemiol 2008;22:288-295.
-
(2008)
Paediatr PerinatEpidemiol
, vol.22
, pp. 288-295
-
-
Blair, C.K.1
Roesler, M.2
Xie, Y.3
-
17
-
-
33750958358
-
Exposure to medical test irradiation and acute leukemia among children with Down syndrome: A report from the Children's Oncology Group
-
Linabery AM, Olshan AF, Gamis AS et al. Exposure to medical test irradiation and acute leukemia among children with Down syndrome: A report from the Children's Oncology Group. Pediatrics 2006;118:e1499-e1508.
-
(2006)
Pediatrics
, vol.118
-
-
Linabery, A.M.1
Olshan, A.F.2
Gamis, A.S.3
-
18
-
-
19944428648
-
Childhood and maternal infections and risk of acute leukaemia in children with Down syndrome: A report from the Children's Oncology Group
-
Canfield KN, Spector LG, Robison LL et al. Childhood and maternal infections and risk of acute leukaemia in children with Down syndrome: A report from the Children's Oncology Group. Br J Cancer 2004;91:1866-1872.
-
(2004)
Br J Cancer
, vol.91
, pp. 1866-1872
-
-
Canfield, K.N.1
Spector, L.G.2
Robison, L.L.3
-
19
-
-
33745076542
-
A prospective study of the natural history of transient leukemia (TL) in neonates with Down syndrome (DS): Children's Oncology Group (COG) study POG-9481
-
Massey GV, Zipursky A, Chang MN et al. A prospective study of the natural history of transient leukemia (TL) in neonates with Down syndrome (DS): Children's Oncology Group (COG) study POG-9481. Blood 2006; 107:4606-4613.
-
(2006)
Blood
, vol.107
, pp. 4606-4613
-
-
Massey, G.V.1
Zipursky, A.2
Chang, M.N.3
-
20
-
-
0942287758
-
Recent insights into the mechanisms of myeloid leukemogenesis in Down syndrome
-
Gurbuxani S, Vyas P, Crispino JD. Recent insights into the mechanisms of myeloid leukemogenesis in Down syndrome. Blood 2004;103:399-406.
-
(2004)
Blood
, vol.103
, pp. 399-406
-
-
Gurbuxani, S.1
Vyas, P.2
Crispino, J.D.3
-
21
-
-
0032845227
-
Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome
-
James SJ, Pogribna M, Pogribny IP et al. Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome. Am J Clin Nutr 1999;70:495-501.
-
(1999)
Am J Clin Nutr
, vol.70
, pp. 495-501
-
-
James, S.J.1
Pogribna, M.2
Pogribny, I.P.3
-
22
-
-
0346966836
-
Role of MTHFR genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia
-
Krajinovic M, Lamothe S, Labuda D et al. Role of MTHFR genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia. Blood 2004;103:252-257.
-
(2004)
Blood
, vol.103
, pp. 252-257
-
-
Krajinovic, M.1
Lamothe, S.2
Labuda, D.3
-
23
-
-
38049069895
-
Trisomy represses Apc(Min)-mediated tumours in mouse models of Down's syndrome
-
Sussan TE, Yang A, Li F et al. Trisomy represses Apc(Min)-mediated tumours in mouse models of Down's syndrome. Nature 2008;451:73-75.
-
(2008)
Nature
, vol.451
, pp. 73-75
-
-
Sussan, T.E.1
Yang, A.2
Li, F.3
-
24
-
-
0035667067
-
High serum endostatin levels in Down syndrome: Implications for improved treatment and prevention of solid tumours
-
Zorick TS, Mustacchi Z, Bando SY et al. High serum endostatin levels in Down syndrome: Implications for improved treatment and prevention of solid tumours. Eur J Hum Genet 2001;9:811-814.
-
(2001)
Eur J Hum Genet
, vol.9
, pp. 811-814
-
-
Zorick, T.S.1
Mustacchi, Z.2
Bando, S.Y.3
-
25
-
-
42449104896
-
Treatment and prognostic impact of transient leukemia in neonates with Down syndrome
-
Klusmann JH, Creutzig U, Zimmermann M et al. Treatment and prognostic impact of transient leukemia in neonates with Down syndrome. Blood 2008;111:2991-2998.
-
(2008)
Blood
, vol.111
, pp. 2991-2998
-
-
Klusmann, J.H.1
Creutzig, U.2
Zimmermann, M.3
-
26
-
-
24744433943
-
GATA1 as a new target to detect minimal residual disease in both transient leukemia and megakaryoblastic leukemia of Down syndrome
-
Pine SR, Guo Q, Yin C et al. GATA1 as a new target to detect minimal residual disease in both transient leukemia and megakaryoblastic leukemia of Down syndrome. Leuk Res 2005;29:1353-1356.
-
(2005)
Leuk Res
, vol.29
, pp. 1353-1356
-
-
Pine, S.R.1
Guo, Q.2
Yin, C.3
-
27
-
-
0026808789
-
Acute myeloid leukemia (AML) in Down's syndrome is highly responsive to chemotherapy: Experience on Pediatric Oncology Group AML Study 8498
-
Ravindranath Y, Abella E, Krischer JP et al. Acute myeloid leukemia (AML) in Down's syndrome is highly responsive to chemotherapy: Experience on Pediatric Oncology Group AML Study 8498. Blood 1992;80: 2210-2214.
-
(1992)
Blood
, vol.80
, pp. 2210-2214
-
-
Ravindranath, Y.1
Abella, E.2
Krischer, J.P.3
-
28
-
-
0030035997
-
A population-based study of 272 children with acute myeloid leukaemia treated on two consecutive protocols with different intensity: Best outcome in girls, infants, and children with Down's syndrome. Nordic Society of Paediatric Haematology and Oncology (NOPHO)
-
Lie SO, Jonmundsson G, Mellander L et al. A population-based study of 272 children with acute myeloid leukaemia treated on two consecutive protocols with different intensity: Best outcome in girls, infants, and children with Down's syndrome. Nordic Society of Paediatric Haematology and Oncology (NOPHO). Br J Haematol 1996;94:82-88.
-
(1996)
Br J Haematol
, vol.94
, pp. 82-88
-
-
Lie, S.O.1
Jonmundsson, G.2
Mellander, L.3
-
29
-
-
0035878006
-
Biology and outcome ofchild - hood acute megakaryoblastic leukemia: A single institution's experience
-
Athale UH, Razzouk BI, Raimondi SC et al. Biology and outcome ofchild - hood acute megakaryoblastic leukemia: A single institution's experience. Blood 2001;97:3727-3732.
-
(2001)
Blood
, vol.97
, pp. 3727-3732
-
-
Athale, U.H.1
Razzouk, B.I.2
Raimondi, S.C.3
-
30
-
-
10044278287
-
Acute myeloid leukemia and Down syndrome evolution of modern therapy-state of the art review
-
Gamis AS. Acute myeloid leukemia and Down syndrome evolution of modern therapy-state of the art review. Pediatr Blood Cancer 2005;44: 13-20.
-
(2005)
Pediatr Blood Cancer
, vol.44
, pp. 13-20
-
-
Gamis, A.S.1
-
31
-
-
16744366910
-
Distinctive demography, biology, and outcome of acute myeloid leukemia and myelodysplastic syndrome in children with Down syndrome: Children's Cancer Group Studies 2861 and 2891
-
Lange BJ, Kobrinsky N, Barnard DR et al. Distinctive demography, biology, and outcome of acute myeloid leukemia and myelodysplastic syndrome in children with Down syndrome: Children's Cancer Group Studies 2861 and 2891. Blood 1998;91:608-615.
-
(1998)
Blood
, vol.91
, pp. 608-615
-
-
Lange, B.J.1
Kobrinsky, N.2
Barnard, D.R.3
-
32
-
-
33646676254
-
Optimal treatment intensity in children with Down syndrome and myeloid leukaemia: Data from 56 children treated on NOPHO-AML protocols and a review of the literature
-
Abildgaard L, Ellebaek E, Gustafsson G et al. Optimal treatment intensity in children with Down syndrome and myeloid leukaemia: Data from 56 children treated on NOPHO-AML protocols and a review of the literature. Ann Hematol 2006;85:275-280.
-
(2006)
Ann Hematol
, vol.85
, pp. 275-280
-
-
Abildgaard, L.1
Ellebaek, E.2
Gustafsson, G.3
-
33
-
-
0033780541
-
The management of neoplastic disorders of haematopoiesis in children with Down's syndrome
-
Lange B. The management of neoplastic disorders of haematopoiesis in children with Down's syndrome. Br J Haematol 2000;110:512-524.
-
(2000)
Br J Haematol
, vol.110
, pp. 512-524
-
-
Lange, B.1
-
34
-
-
0034094596
-
Aneffective chemotherapeuticregimenfor acute myeloid leukemia and myelodysplastic syndrome in children with Down's syndrome
-
KojimaS, Sako M, Kato K et al. Aneffective chemotherapeuticregimenfor acute myeloid leukemia and myelodysplastic syndrome in children with Down's syndrome. Leukemia 2000;14:786-791.
-
(2000)
Leukemia
, vol.14
, pp. 786-791
-
-
Kojima, S.1
Sako, M.2
Kato, K.3
-
35
-
-
36849053313
-
Prospective study of a irarubicin, intermediate-dose cytarabine, and etoposide regimen in children with Down syndrome and acute myeloid leukemia: The Japanese Childhood AML Cooperative Study Group
-
Kudo K, Kojima S, Tabuchi K et al. Prospective study of a irarubicin, intermediate-dose cytarabine, and etoposide regimen in children with Down syndrome and acute myeloid leukemia: The Japanese Childhood AML Cooperative Study Group. J Clin Oncol 2007;25:5442-5447.
-
(2007)
J Clin Oncol
, vol.25
, pp. 5442-5447
-
-
Kudo, K.1
Kojima, S.2
Tabuchi, K.3
-
36
-
-
33646701894
-
Long-term results ofan ultra low-dose cytarabine-based regimen for the treatment of acute megakaryoblastic leukaemia in children with Down syndrome
-
Al-Ahmari A, Shah N, Sung L et al. Long-term results ofan ultra low-dose cytarabine-based regimen for the treatment of acute megakaryoblastic leukaemia in children with Down syndrome. Br J Haematol 2006;133:646-648.
-
(2006)
Br J Haematol
, vol.133
, pp. 646-648
-
-
Al-Ahmari, A.1
Shah, N.2
Sung, L.3
-
38
-
-
0036727413
-
Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome
-
Wechsler J, Greene M, McDevitt MA et al. Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome. Nat Genet 2002;32: 148 - 152.
-
(2002)
Nat Genet
, vol.32
, pp. 148-152
-
-
Wechsler, J.1
Greene, M.2
McDevitt, M.A.3
-
39
-
-
0038142390
-
Mutagenesis ofGATA1 is an initiating event in Down syndrome leukemogenesis
-
Mundschau G, Gurbuxani S, Gamis AS et al. Mutagenesis ofGATA1 is an initiating event in Down syndrome leukemogenesis. Blood 2003;101: 4298-4300.
-
(2003)
Blood
, vol.101
, pp. 4298-4300
-
-
Mundschau, G.1
Gurbuxani, S.2
Gamis, A.S.3
-
40
-
-
0037325661
-
A pediatric approach to the WHO classification of myelodysplastic and myeloproliferative diseases
-
Hasle H, Niemeyer CM, Chessells JM et al. A pediatric approach to the WHO classification of myelodysplastic and myeloproliferative diseases. Leukemia 2003;17:277-282.
-
(2003)
Leukemia
, vol.17
, pp. 277-282
-
-
Hasle, H.1
Niemeyer, C.M.2
Chessells, J.M.3
-
41
-
-
12144287045
-
Natural history of GATA1 mutations in Down syndrome
-
Ahmed M, Sternberg A, Hall G et al. Natural history of GATA1 mutations in Down syndrome. Blood 2004;103:2480-2489.
-
(2004)
Blood
, vol.103
, pp. 2480-2489
-
-
Ahmed, M.1
Sternberg, A.2
Hall, G.3
-
42
-
-
0042243593
-
Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21
-
Rainis L, Bercovich D, Strehl S et al. Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21. Blood 2003;102:981-986.
-
(2003)
Blood
, vol.102
, pp. 981-986
-
-
Rainis, L.1
Bercovich, D.2
Strehl, S.3
-
43
-
-
20044381309
-
Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1
-
Li Z, Godinho FJ, Klusmann JH et al. Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1. Nat Genet 2005;37:613-619.
-
(2005)
Nat Genet
, vol.37
, pp. 613-619
-
-
Li, Z.1
Godinho, F.J.2
Klusmann, J.H.3
-
44
-
-
33745579586
-
An inherited mutation leading to production of only the short isoform of GATA-1 is associated with impaired erythropoiesis
-
Hollanda LM, Lima CS, Cunha AF et al. An inherited mutation leading to production of only the short isoform of GATA-1 is associated with impaired erythropoiesis. Nat Genet 2006;38:807-812.
-
(2006)
Nat Genet
, vol.38
, pp. 807-812
-
-
Hollanda, L.M.1
Lima, C.S.2
Cunha, A.F.3
-
45
-
-
30144433626
-
Early block to erythromegakaryocytic development conferred by loss of transcription factor GATA-1
-
Stachura DL, Chou ST, Weiss MJ. Early block to erythromegakaryocytic development conferred by loss of transcription factor GATA-1. Blood 2006;107:87-97.
-
(2006)
Blood
, vol.107
, pp. 87-97
-
-
Stachura, D.L.1
Chou, S.T.2
Weiss, M.J.3
-
46
-
-
0141889275
-
Frequent mutations in the GATA-1 gene in the transientmyeloproliferative disorderofDown syndrome
-
Xu G, Nagano M, Kanezaki R et al. Frequent mutations in the GATA-1 gene in the transientmyeloproliferative disorderofDown syndrome. Blood 2003;102:2960-2968.
-
(2003)
Blood
, vol.102
, pp. 2960-2968
-
-
Xu, G.1
Nagano, M.2
Kanezaki, R.3
-
48
-
-
6344281019
-
Distinct gene signatures of transient and acute megakaryoblastic leukemia in Down syndrome
-
Lightfoot J, Hitzler JK, Zipursky A et al. Distinct gene signatures of transient and acute megakaryoblastic leukemia in Down syndrome. Leukemia 2004;18:1617-1623.
-
(2004)
Leukemia
, vol.18
, pp. 1617-1623
-
-
Lightfoot, J.1
Hitzler, J.K.2
Zipursky, A.3
-
49
-
-
3042636440
-
Microarray transcriptprofiling distinguishes the transient from the acute type of megakaryoblastic leukaemia (M7) in Down's syndrome, revealing PRAME as a specific discriminating marker
-
McElwaine S, Mulligan C, Groet J et al. Microarray transcriptprofiling distinguishes the transient from the acute type of megakaryoblastic leukaemia (M7) in Down's syndrome, revealing PRAME as a specific discriminating marker. Br J Haematol 2004;125:729-742.
-
(2004)
Br J Haematol
, vol.125
, pp. 729-742
-
-
McElwaine, S.1
Mulligan, C.2
Groet, J.3
-
50
-
-
33745713168
-
Activating alleles of JAK3 in acute megakaryoblastic leukemia
-
Walters DK, Mercher T, Gu TL et al. Activating alleles of JAK3 in acute megakaryoblastic leukemia. Cancer Cell 2006;10:65-75.
-
(2006)
Cancer Cell
, vol.10
, pp. 65-75
-
-
Walters, D.K.1
Mercher, T.2
Gu, T.L.3
-
51
-
-
33847202261
-
JAK3 mutations occur in acute megakaryoblastic leukemia both in Down syndrome children and non - Down syndrome adults
-
Kiyoi H, Yamaji S, Kojima S et al. JAK3 mutations occur in acute megakaryoblastic leukemia both in Down syndrome children and non - Down syndrome adults. Leukemia 2007;21:574-576.
-
(2007)
Leukemia
, vol.21
, pp. 574-576
-
-
Kiyoi, H.1
Yamaji, S.2
Kojima, S.3
-
52
-
-
34250733916
-
Janus kinase mutations in the development of acute megakaryoblastic leukemia in children with and without Down's syndrome
-
Klusmann JH, Reinhardt D, Hasle H et al. Janus kinase mutations in the development of acute megakaryoblastic leukemia in children with and without Down's syndrome. Leukemia 2007;21:1584-1587.
-
(2007)
Leukemia
, vol.21
, pp. 1584-1587
-
-
Klusmann, J.H.1
Reinhardt, D.2
Hasle, H.3
-
53
-
-
34547946210
-
Analysis ofJAK3, JAK2, and C-MPL mutations in transient myeloproliferative disorder and myeloid leukemia of Down syndrome blasts in children with Down syndrome
-
Norton A, Fisher C, Liu H et al. Analysis ofJAK3, JAK2, and C-MPL mutations in transient myeloproliferative disorder and myeloid leukemia of Down syndrome blasts in children with Down syndrome. Blood 2007;110:1077-1079.
-
(2007)
Blood
, vol.110
, pp. 1077-1079
-
-
Norton, A.1
Fisher, C.2
Liu, H.3
-
54
-
-
54049107944
-
Activating mutations in human acute megakaryoblastic leukemia
-
Malinge S, Ragu C, Della-Valle V et al. Activating mutations in human acute megakaryoblastic leukemia. Blood 2008;112:4220-4226.
-
(2008)
Blood
, vol.112
, pp. 4220-4226
-
-
Malinge, S.1
Ragu, C.2
Della-Valle, V.3
-
55
-
-
0027276321
-
Immunophenotypes and karyotypes of leukemic cells in children with Down syndrome and acute lymphoblastic leukemia
-
Pui CH, Raimondi SC, Borowitz MJ et al. Immunophenotypes and karyotypes of leukemic cells in children with Down syndrome and acute lymphoblastic leukemia. J Clin Oncol 1993;11:1361-1367.
-
(1993)
J Clin Oncol
, vol.11
, pp. 1361-1367
-
-
Pui, C.H.1
Raimondi, S.C.2
Borowitz, M.J.3
-
57
-
-
0034809324
-
Down's syndrome and acute lymphoblastic leukaemia: Clinical features and response to treatment
-
Chessells JM, Harrison G, Richards SM et al. Down's syndrome and acute lymphoblastic leukaemia: Clinical features and response to treatment. Arch Dis Child 2001;85:321-325.
-
(2001)
Arch Dis Child
, vol.85
, pp. 321-325
-
-
Chessells, J.M.1
Harrison, G.2
Richards, S.M.3
-
58
-
-
20144388603
-
Acute leukaemia in children with Down syndrome: A population-based Nordic study
-
Zeller B, Gustafsson G, Forestier E et al. Acute leukaemia in children with Down syndrome: A population-based Nordic study. Br J Haematol 2005;128:797-804.
-
(2005)
Br J Haematol
, vol.128
, pp. 797-804
-
-
Zeller, B.1
Gustafsson, G.2
Forestier, E.3
-
59
-
-
10044239576
-
Lymphoblast biology and outcome among children with Down syndrome and ALL treated on CCG-1952
-
Bassal M, La MK, Whitlock JA et al. Lymphoblast biology and outcome among children with Down syndrome and ALL treated on CCG-1952. Pediatr Blood Cancer 2005;44:21-28.
-
(2005)
Pediatr Blood Cancer
, vol.44
, pp. 21-28
-
-
Bassal, M.1
MK, L.2
Whitlock, J.A.3
-
60
-
-
28844446288
-
Clinical characteristics and outcome of children with Down syndrome and acute lymphoblastic leukemia: A Children's Cancer Group study
-
Whitlock JA, Sather HN, Gaynon P et al. Clinical characteristics and outcome of children with Down syndrome and acute lymphoblastic leukemia: A Children's Cancer Group study. Blood 2005;106:4043-4049.
-
(2005)
Blood
, vol.106
, pp. 4043-4049
-
-
Whitlock, J.A.1
Sather, H.N.2
Gaynon, P.3
-
61
-
-
49049105472
-
Acute lymphoblastic leukemia and Down syndrome: Presenting features and treatment outcome in the experience of the Italian Association of Pediatric Hematology and Oncology (AIEOP)
-
Arico M, Ziino O, Valsecchi MG et al. Acute lymphoblastic leukemia and Down syndrome: Presenting features and treatment outcome in the experience of the Italian Association of Pediatric Hematology and Oncology (AIEOP). Cancer 2008;113:515-521.
-
(2008)
Cancer
, vol.113
, pp. 515-521
-
-
Arico, M.1
Ziino, O.2
Valsecchi, M.G.3
-
62
-
-
38949098169
-
Cytogenetic features of acute lymphoblastic and myeloid leukemias in pediatric patients with Down syndrome: AniBFM-SG study
-
Forestier E, Izraeli S, Beverloo B et al. Cytogenetic features of acute lymphoblastic and myeloid leukemias in pediatric patients with Down syndrome: AniBFM-SG study. Blood 2008;111:1575-1583.
-
(2008)
Blood
, vol.111
, pp. 1575-1583
-
-
Forestier, E.1
Izraeli, S.2
Beverloo, B.3
-
63
-
-
64149096544
-
Comparison of the biology of Down syndrome (DS) acute lymphoblastic leukemia (ALL) and non-DS ALL: Children's Oncology Group study P9900
-
Maloney KW, Carroll WL, Carroll A et al. Comparison of the biology of Down syndrome (DS) acute lymphoblastic leukemia (ALL) and non-DS ALL: Children's Oncology Group study P9900. J Clin Oncol 2008;26(15 suppl):10003a.
-
(2008)
J Clin Oncol
, vol.26
, Issue.15 SUPPL.
-
-
Maloney, K.W.1
Carroll, W.L.2
Carroll, A.3
-
64
-
-
54349086521
-
Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome
-
Bercovich D, Ganmore I, Scott LM et al. Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome. Lancet 2008; 372:1484-1492.
-
(2008)
Lancet
, vol.372
, pp. 1484-1492
-
-
Bercovich, D.1
Ganmore, I.2
Scott, L.M.3
-
65
-
-
17844383458
-
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
-
James C, Ugo V, Le Couedic JP et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 2005;434: 1144-1148.
-
(2005)
Nature
, vol.434
, pp. 1144-1148
-
-
James, C.1
Ugo, V.2
Le Couedic, J.P.3
-
66
-
-
77953368910
-
Improved outcome of children with Down syndrome and high risk acute lymphocytic leukemia: A report of CCG-1961
-
Hastings C, Whitlock JA, La M et al. Improved outcome of children with Down syndrome and high risk acute lymphocytic leukemia: A report of CCG-1961. Blood 2007;110:586a.
-
(2007)
Blood
, vol.110
-
-
Hastings, C.1
Whitlock2
JA, L.M.3
-
67
-
-
33750547601
-
Down syndrome and acute lymphoblastic leukaemia
-
Whitlock JA. Down syndrome and acute lymphoblastic leukaemia. Br J Haematol 2006;135:595-602.
-
(2006)
Br J Haematol
, vol.135
, pp. 595-602
-
-
Whitlock, J.A.1
-
68
-
-
0036098159
-
Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome
-
Zwaan CM, Kaspers GJ, Pieters R et al. Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome. Blood 2002;99:245-251.
-
(2002)
Blood
, vol.99
, pp. 245-251
-
-
Zwaan, C.M.1
Kaspers, G.J.2
Pieters, R.3
-
69
-
-
0033566994
-
Expression of chromosome 21-localized genes in acute myeloid leukemia: Differences between Down syndrome and non-Down syndrome blast cells and relationship to in vitro sensitivity to cytosine arabinoside and daunorubicin
-
Taub JW, Huang X, Matherly LH et al. Expression of chromosome 21-localized genes in acute myeloid leukemia: Differences between Down syndrome and non-Down syndrome blast cells and relationship to in vitro sensitivity to cytosine arabinoside and daunorubicin. Blood 1999;94:1393-1400.
-
(1999)
Blood
, vol.94
, pp. 1393-1400
-
-
Taub, J.W.1
Huang, X.2
Matherly, L.H.3
-
70
-
-
32644453700
-
Differential gene expression, GATA1 target genes, and the chemotherapy sensitivity of Down syndrome megakaryocyticleukemia
-
Ge Y, Dombkowski AA, LaFiura KM et al. Differential gene expression, GATA1 target genes, and the chemotherapy sensitivity of Down syndrome megakaryocyticleukemia Blood 2006;107:1570-1581.
-
(2006)
Blood
, vol.107
, pp. 1570-1581
-
-
Ge, Y.1
Dombkowski, A.A.2
LaFiura, K.M.3
-
71
-
-
10044264623
-
Down syndrome, drug metabolism and chromosome 21
-
Taub JW, Ge Y. Down syndrome, drug metabolism and chromosome 21. Pediatr Blood Cancer 2005;44:33-39.
-
(2005)
Pediatr Blood Cancer
, vol.44
, pp. 33-39
-
-
Taub, J.W.1
Ge, Y.2
-
72
-
-
1642475113
-
The role of cytidine deaminase and GATA1 mutations in the increased cytosine arabinoside sensitivity of Down syndrome myeloblasts and leukemia cell lines
-
Ge Y, Jensen TL, Stout ML et al. The role of cytidine deaminase and GATA1 mutations in the increased cytosine arabinoside sensitivity of Down syndrome myeloblasts and leukemia cell lines. Cancer Res 2004;64: 728-735.
-
(2004)
Cancer Res
, vol.64
, pp. 728-735
-
-
Ge, Y.1
Jensen, T.L.2
Stout, M.L.3
-
73
-
-
0030904457
-
Clinical cardiotoxicity following anthracycline treatment for childhood cancer: The Pediatric Oncology Groupexperience
-
Krischer JP, Epstein S, Cuthbertson DD et al. Clinical cardiotoxicity following anthracycline treatment for childhood cancer: The Pediatric Oncology Groupexperience. J Clin Oncol 1997;15:1544-1552.
-
(1997)
J Clin Oncol
, vol.15
, pp. 1544-1552
-
-
Krischer, J.P.1
Epstein, S.2
Cuthbertson, D.D.3
-
74
-
-
38649095184
-
-
O'Brien MM, Taub JW, Chang MN et al. Cardiomyopathy in children with Down syndrome treated for acute myeloid leukemia: A report from the Children's OncologyGroupStudy POG 9421. JClinOncol2008;26:414-420.
-
O'Brien MM, Taub JW, Chang MN et al. Cardiomyopathy in children with Down syndrome treated for acute myeloid leukemia: A report from the Children's OncologyGroupStudy POG 9421. JClinOncol2008;26:414-420.
-
-
-
-
75
-
-
37148999073
-
DNA damage and repair in children with Down's syndrome
-
Morawiec Z, Janik K, Kowalski M et al. DNA damage and repair in children with Down's syndrome. MutatRes 2008;637:118-123.
-
(2008)
MutatRes
, vol.637
, pp. 118-123
-
-
Morawiec, Z.1
Janik, K.2
Kowalski, M.3
-
76
-
-
34248205623
-
Longitudinal evaluation of early and late anthracycline cardiotoxicity in children with AML
-
Creutzig U, Diekamp S, Zimmermann M et al. Longitudinal evaluation of early and late anthracycline cardiotoxicity in children with AML. Pediatr Blood Cancer 2007;48:651-662.
-
(2007)
Pediatr Blood Cancer
, vol.48
, pp. 651-662
-
-
Creutzig, U.1
Diekamp, S.2
Zimmermann, M.3
-
77
-
-
0034106858
-
Cellular cytotoxic drug sensitivity in children with acute leukemia and Down's syndrome: An explanation to differences in clinical outcome?
-
Frost BM, Gustafsson G, Larsson R et al. Cellular cytotoxic drug sensitivity in children with acute leukemia and Down's syndrome: An explanation to differences in clinical outcome? Leukemia 2000;14:943-944.
-
(2000)
Leukemia
, vol.14
, pp. 943-944
-
-
Frost, B.M.1
Gustafsson, G.2
Larsson, R.3
-
78
-
-
0025580086
-
Clinical and biological characteristics ofacute lymphocyticleukemiainchildrenwithDownsyndrome
-
Kalwinsky DK, Raimondi SC, Bunin NJ et al. Clinical and biological characteristics ofacute lymphocyticleukemiainchildrenwithDownsyndrome. Am J Med GenetSuppl 1990;7:267-271.
-
(1990)
Am J Med GenetSuppl
, vol.7
, pp. 267-271
-
-
Kalwinsky, D.K.1
Raimondi, S.C.2
Bunin, N.J.3
-
79
-
-
0023200576
-
Pharmacokinetics and toxicity of methotrexate in children with Down syndrome and acute lymphocytic leukemia
-
Garre ML, Relling MV, Kalwinsky D et al. Pharmacokinetics and toxicity of methotrexate in children with Down syndrome and acute lymphocytic leukemia. J Pediatr1987;111:606-612.
-
J Pediatr1987;111
, pp. 606-612
-
-
Garre, M.L.1
Relling, M.V.2
Kalwinsky, D.3
-
80
-
-
0023187384
-
Down syndrome and leukemia: Unusual clinical aspects and unexpected methotrexate sensitivity
-
Peeters M, Poon A. Down syndrome and leukemia: Unusual clinical aspects and unexpected methotrexate sensitivity. Eur J Pediatr 1987;146: 416-422.
-
(1987)
Eur J Pediatr
, vol.146
, pp. 416-422
-
-
Peeters, M.1
Poon, A.2
-
81
-
-
0023006905
-
Excessive chemotherapy-related myelotoxicity in children with Down syndrome and acute lymphoblastic leukaemia
-
Blatt J, Albo V, Prin W et al. Excessive chemotherapy-related myelotoxicity in children with Down syndrome and acute lymphoblastic leukaemia. Lancet1986;2:914.
-
Lancet1986;2
, vol.914
-
-
Blatt, J.1
Albo, V.2
Prin, W.3
-
82
-
-
0031669954
-
Reduced folate carrier gene expression in childhood acute lymphoblastic leukemia: Relationship to immunophenotype and ploidy
-
Zhang L, Taub JW, Williamson M et al. Reduced folate carrier gene expression in childhood acute lymphoblastic leukemia: Relationship to immunophenotype and ploidy. Clin Cancer Res 1998;4:2169-2177.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 2169-2177
-
-
Zhang, L.1
Taub, J.W.2
Williamson, M.3
-
84
-
-
56949088952
-
Differential in vitro cytotoxicity does notexplain increased host toxicities from chemotherapy in Down syndrome acute lymphoblastic leukemia
-
Valle M, Plon SE, Rabin KR. Differential in vitro cytotoxicity does notexplain increased host toxicities from chemotherapy in Down syndrome acute lymphoblastic leukemia. Leuk Res 2009;33:336-339.
-
(2009)
Leuk Res
, vol.33
, pp. 336-339
-
-
Valle, M.1
Plon, S.E.2
Rabin, K.R.3
-
85
-
-
0015521803
-
Leucocyte function in Down's syndrome and acute leukaemia
-
Gregory L, Williams R, Thompson E. Leucocyte function in Down's syndrome and acute leukaemia. Lancet1972;1:1359-1361.
-
Lancet1972;1
, pp. 1359-1361
-
-
Gregory, L.1
Williams, R.2
Thompson, E.3
-
86
-
-
0019474669
-
KornEet al. Altered cellular immune functions inpatients with Down's syndrome
-
SpinaCA, SmithD, KornEet al. Altered cellular immune functions inpatients with Down's syndrome. Am J Dis Child 1981;135:251-255.
-
(1981)
Am J Dis Child
, vol.135
, pp. 251-255
-
-
SpinaCA1
SmithD2
-
87
-
-
0025685042
-
Humoral immunodeficiencies in Down syndrome: Serum IgG subclass and antibody response to hepatitis B vaccine
-
Avanzini MA, Monafo V, De Amici M et al. Humoral immunodeficiencies in Down syndrome: Serum IgG subclass and antibody response to hepatitis B vaccine. Am J Med GenetSuppl 1990;7:231-233.
-
(1990)
Am J Med GenetSuppl
, vol.7
, pp. 231-233
-
-
Avanzini, M.A.1
Monafo, V.2
De Amici, M.3
-
89
-
-
0033016392
-
Improved outcome of acute my-eloid leukaemia in Down's syndrome
-
Craze JL, Harrison G, Wheatley K et al. Improved outcome of acute my-eloid leukaemia in Down's syndrome. Arch Dis Child 1999;81:32-37.
-
(1999)
Arch Dis Child
, vol.81
, pp. 32-37
-
-
Craze, J.L.1
Harrison, G.2
Wheatley, K.3
-
90
-
-
28544443076
-
ClausenNet al. Long-termresultsinchildrenwith AML: NOPHO-AML Study Group-report of three consecutive trials
-
LieSO, AbrahamssonJ, ClausenNet al. Long-termresultsinchildrenwith AML: NOPHO-AML Study Group-report of three consecutive trials. Leukemia 2005;19:2090-2100.
-
(2005)
Leukemia
, vol.19
, pp. 2090-2100
-
-
LieSO1
AbrahamssonJ2
-
91
-
-
9344226161
-
Autologous bone marrow transplantation versus intensive consolidation chemotherapy for acute myeloid leukemia in childhood. Pediatric Oncology Group
-
Ravindranath Y, Yeager AM, Chang MN et al. Autologous bone marrow transplantation versus intensive consolidation chemotherapy for acute myeloid leukemia in childhood. Pediatric Oncology Group. N Engl J Med 1996;334:1428-1434.
-
(1996)
N Engl J Med
, vol.334
, pp. 1428-1434
-
-
Ravindranath, Y.1
Yeager, A.M.2
Chang, M.N.3
|