A population-based study of 272 children with acute myeloid leukaemia treated on two consecutive protocols with different intensity: Best outcome in girls, infants, and children with Down's syndrome

British Journal of Haematology

Volumn 94, Issue 1, 1996, Pages 82-88

  Lie, Sverre O ^a   Jonmundsson, Gudmundur ^b   Mellander, Lotta ^c   Siimes, Martti A ^d   Yssing, Minna ^e   Gustafsson, Göran ^f  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b LANDSPITALI UNIVERSITY HOSPITAL   (Iceland)

^c SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^d UNIVERSITY OF HELSINKI   (Finland)

^e Rigshospitalet   (Denmark)

^f KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Children; Leukaemia; Myeloid; Nordic; Therapy

Indexed keywords

CYTARABINE; DOXORUBICIN; ETOPOSIDE; METHOTREXATE; MITOXANTRONE; TIOGUANINE;

ACUTE GRANULOCYTIC LEUKEMIA; ADOLESCENT; ARTICLE; CANCER INCIDENCE; CANCER RECURRENCE; CHILD; CHILDHOOD LEUKEMIA; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOWN SYNDROME; FEMALE; HUMAN; INFANT; INTRATHECAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PRIORITY JOURNAL; PROGNOSIS; SCANDINAVIA; SEX DIFFERENCE;

EID: 0030035997     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1996.d01-1761.x     Document Type: Article

References (27)

1. Amadori, S., Testi, A.M., Arico, M., Gomelli, A., Giuilano, M., Madon, E., Masera, G., Randelli, R., Zanesco, L., & Mandelli, F. (1993) Prospective comparative study of bone marrow transplantation and postremission chemotherapy for childhood acute myelogenous leukaemia. Journal of Clinical Oncology, 11, 1046-1054.
2. Boulad, F. & Kernan, N.A. (1993) Treatment of childhood acute nonlymphoblastic leukemia: a review. Cancer Investigation, 11, 534-553.
3. Cox, D. (1972) Regression models and life-tables. Journal of the Royal Statistical Society, B4, 187-202.
4. Creutzig, U., Ritter, J. & Schellong, G. (1990) Identification of two risk groups in childhood acute myelogenous leukemia after therapy intensification in study AML-BFM-83 as compared with study AML-BFM-78. Blood, 75, 1932-1940.
5. Creutzig, U., Ritter, J., Zimmermann, M. & Schellong, G. (1993) Does cranial irradiation reduce the risk for bone marrow relapse in acute myelogenous leukaemia? Unexpected results of the childhood acute myelogenous leukaemia study BFM-87. Journal of Clinical Oncology, 11, 279-286.
6. Kaplan, E.L. & Meier, P. (1958) Non-parametric estimation from incomplete observations. Journal of the American Statistical Association, 53, 457-481.
7. Lanning, M., Garwicz, S., Hertz, H., Jonmundsson, G., Kreuger. A., Lie, S.O., Moe, P.J., Salmi, T.T., Schrøder, H., Siimes, M.A., Wesenberg, F., Yssing, M., Åhstrøm, L. & Gustafsson, G. (1992) Superior treatment results in females with high-risk acute lymphoblastic leukemia in childhood. Acta Paediatrica, 81, 66-68.
8. Lie, S.O. (1989) Acute myelogenous leukaemia in children. European Journal of Pediatrics, 148, 382-388.
9. Lie, S.O., Berglund, G., Gustafsson, G., Jonmundsson, G., Siimes, M. & Yssing, M. (1990) High-dose Ara-C as a single-agent consolidation therapy in childhood acute myelogenous leukaemia. Haematology and Blood Transfusion, 33, 215-221.
10. Lie, S.O. & Gustafsson, G. (1992) Progress in the treatment of childhood leukaemias. Annals of Medicine, 24, 319-323.
11. Mantel, N. (1966) Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemotherapy, 50, 163-170.
12. Neglia, J.P. & Robison, L.L. (1988) Epidemiology of the childhood acute leukemias. Pediatric Clinics of North America, 35, 674-692.
13. Nesbit, M.E., Buckley, I.D., Feig, S.A., Anderson, J.R., Lampkin, B., Bernstein. I.D., Kirn. T.H., Piomelli, S., Kersey, J.H., Coccia, P.F., O'Reilly, R.C., August, C., Thomas, E.D. & Hammond, G.D. (1994) Chemotherapy for induction of remission of childhood acute myeloid leukaemia followed by marrow transplantation or multiagent chemotherapy: a report from the Childrens Cancer Group. Journal of Clinical Oncology, 12, 127-135.
14. Norusis, M.J. (1992) SPSS Statistical Software 5.0 for Windows. SPSS Inc., Chicago, Ill.
15. Novakovic, B. (1994) U.S. childhood cancer survival, 1973-1987. Medical and Pediatric Oncology, 23, 480-486.
16. Ravindranath, Y., Abella, E., Krischer, J.P., Wiley, J., Inoue, S., Harris, M., Chauvenet, A., Alvarado, C.S., Dubowy, R., Ritchey, A.K., Land, V., Steuber, C.P. & Weinstein, H. (1992) Acute myeloid leukemia (AML) in Down's syndrome is highly responsive to chemotherapy: experience on Pediatric Oncology Group AML Study 8498. Blood, 80, 2210-2214.
17. Ravindranath, Y. & Schultz, K.R. (1994) Acute myeloid leukaemias. Neoplastic Diseases of Childhood (ed. by C. Pochedly), Vol. 1, pp. 519-540. Harwood Academic Publishers, London.
18. Ravindranath, Y., Steuber, C.P., Krischer, J., Civin, C.I., Ducore, J., Vega, R., Pitel, P., Inoue, S., Bleher, K., Sexauer, C., Hutter, J. & Vietti, T. (1991) High-dose cytarabine for intensification of early therapy of childhood acute myeloid leukaemia: a Pediatric Oncology Group Study. Journal of Clinical Oncology, 9, 572-580.
19. Robison, L.L., Nesbit, M.E., Sather, H.N., Level, C., Shahidi, N., Kennedy, A. & Hammond, D. (1984) Down syndrome and acute leukemia in children: a 10-year retrospective survey from Childrens Cancer Study Group. Journal of Pediatrics, 105, 235-242.
20. Slørdahl, S.H., Gustafsson, G., Jonmundsson, G., Mellander, L., Siimes, M.A., Yssing, M. & Lie, S.O. (1992) Down's syndrome (DS) and acute myelogenous leukemia (AML): a population-based study in the live Nordic countries. (Abstract). Medical and Pediatric Oncology, 20, 573.
21. Slørdahl, S.H., Smeland, E.B., Holte, H., Grønn, M., Lie, S.O. & Seip, M. (1993) Leukemic blasts with markers of four cell lineages in Down's syndrome ('megakaryoblastic leukemia'). Medical and Pediatric Oncology, 21, 254-258.
22. Stevens, R.F., Hann, I.M., Burnett, A.K., Goldstone, A.H., Wheatley, K. & Gray, R.G. (1994) Improved outcome in pediatric acute myeloid leukemia: results of the MRC AML 10 Trial. (Abstract). Medical and Pediatric Oncology, 23, 172.
23. Stiller, C.A. & Eatock, E.M. (1994) Survival from acute non-lymphocytic leukaemia, 1971-88: a population-based study. Archives of Disease in Childhood, 70, 219-223.
24. Wells, R.J., Woods, W.G., Buckley, J.D., Odom, L.F., Benjamin, D., Bernstein, J., Betcher, D., Feig, S., Kim, T., Ruymann, F., Smithson, W., Srivastava, A., Tannous, R., Buckley, C.M., Whitt, J.K., Wolff, L. & Lampkin, B.C. (1994) Treatment of newly diagnosed children and adolescents with acute myeloid leukaemia: a Childrens Cancer Group Study. Journal of Clinical Oncology, 12, 2367-2377.
25. Woods, W.G., Kobrinsky, N., Buckley, J., Neudorf, S., Sanders, J., Miller, L., Barnard, D., Benjamin, D., DeSwarte, J., Kalousek, D. & Lange, B.J. (1994) Timing intensive induction therapy improves post-remission outcome in acute myeloid leukemia (AML) irrespective of the use of bone marrow transplantation (BMT). Blood, 84, (Suppl. 1), 232a.
26. Woods, W.G., Kobrinsky, N., Buckley, J., Neudorf, S., Sanders, J., Miller, L., Barnard, D., Benjamin, D., de Swarte, J., Kalousek, D., Shina, D., Hammond, G.D. & Lange, B.J. (1993) Intensively timed induction therapy followed by autologous or allogeneic bone marrow transplantation for children with acute myeloid leukaemia or myelodysplastic syndrome: a Childrens Cancer Group pilot study. Journal of Clinical Oncology, 11, 1448-1457.
27. Zipursky, A., Poon, A. & Doyle, J. (1992) Leukemia in Down syndrome: a review. Pediatric Hematology and Oncology, 9, 139-149.