Lentiviral vectors encoding human MUC1-specific, MHC-unrestricted single-chain TCR and a fusion suicide gene: Potential for universal and safe cancer immunotherapy

Cancer Immunology, Immunotherapy

Volumn 58, Issue 6, 2009, Pages 977-987

  Chen, Xiaochuan ^a,b   Gao, Wentao ^a   Gambotto, Andrea ^a   Finn, Olivera J ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b CENTER FOR MOLECULAR MEDICINE AND IMMUNOLOGY   (United States)

Author keywords

Cancer immunotherapy; Lentiviral vector; MUC1; T cell receptor (TCR)

Indexed keywords

GANCICLOVIR; LENTIVIRUS VECTOR; MUCIN 1; SING CHAIN T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER IMMUNOTHERAPY; CELL LINE; CONTROLLED STUDY; FUSION GENE; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUICIDE GENE; T LYMPHOCYTE; T LYMPHOCYTE RECEPTOR GENE; TRANSGENE; VIRUS TITRATION;

ANIMALS; ANTIVIRAL AGENTS; CELL SURVIVAL; FLOW CYTOMETRY; GANCICLOVIR; GENES, TRANSGENIC, SUICIDE; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; LENTIVIRUS; MICE; MICE, TRANSGENIC; MUCIN-1; RECEPTORS, ANTIGEN, T-CELL; RETROVIRIDAE; SIMPLEXVIRUS; T-LYMPHOCYTES; THYMIDINE KINASE; TRANSDUCTION, GENETIC;

EID: 63949084695     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-008-0624-0     Document Type: Article

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