Mutational Analysis of the Transferrin Receptor Reveals Overlapping HFE and Transferrin Binding Sites

Journal of Molecular Biology

Volumn 313, Issue 2, 2001, Pages 385-397

  West, Anthony P ^a   Giannetti, Anthony M ^a   Herr, Andrew B ^a   Bennett, Melanie J ^a   Nangiana, Jasvinder S ^a,b   Pierce, James R ^a,c   Weiner, Leslie P ^a,d   Snow, Peter M ^a   Bjorkman, Pamela J ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b University of California Berkeley   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Class I MHC homolog; Functional epitope; HFE; Iron overload; Surface plasmon resonance

Indexed keywords

HFE PROTEIN, HUMAN; HLA ANTIGEN; HLA ANTIGEN CLASS 1; LIGAND; MEMBRANE PROTEIN; TRANSFERRIN; TRANSFERRIN RECEPTOR;

ARTICLE; BINDING COMPETITION; CHEMICAL STRUCTURE; CHEMISTRY; GEL CHROMATOGRAPHY; GENETICS; HUMAN; KINETICS; MACROMOLECULE; METABOLISM; MOLECULAR WEIGHT; MUTATION; PROTEIN CONFORMATION; SURFACE PLASMON RESONANCE; THERMODYNAMICS; ULTRACENTRIFUGATION;

BINDING, COMPETITIVE; CHROMATOGRAPHY, GEL; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; KINETICS; LIGANDS; MACROMOLECULAR SUBSTANCES; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR WEIGHT; MUTATION; PROTEIN CONFORMATION; RECEPTORS, TRANSFERRIN; SURFACE PLASMON RESONANCE; THERMODYNAMICS; TRANSFERRIN; ULTRACENTRIFUGATION;

EID: 0035914480     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.5048     Document Type: Article

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