2-Azidoalkoxy-7-hydro-8-oxoadenine derivatives as TLR7 agonists inducing dendritic cell maturation

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 8, 2009, Pages 2249-2251

  Weterings, Jimmy J ^a   Khan, Selina ^b   van der Heden van Noort, Gerbrand J ^a   Melief, Cornelis J M ^b   Overkleeft, Herman S ^a   van der Burg, Sjoerd H ^b   Ossendorp, Ferry ^b   van der Marel, Gijsbert A ^a   Filippov, Dmitri V ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

7 Hydro 8 oxoadenine; Dendritic cell; TLR 7

Indexed keywords

2 AZIDOALKOXY 7 HYDRO 8 OXOADENINE DERIVATIVE; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 7 AGONIST; TOLL LIKE RECEPTOR AGONIST; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MATURATION; DENDRITIC CELL; DRUG EFFECT; DRUG STRUCTURE; DRUG SYNTHESIS; MOUSE; NONHUMAN; REACTION ANALYSIS; STRUCTURE ANALYSIS;

ADENINE; AMINES; ANIMALS; AZIDES; CELL DIFFERENTIATION; DENDRITIC CELLS; MICE; TOLL-LIKE RECEPTOR 7;

EID: 63149175990     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.02.095     Document Type: Article

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