Synthesis and structure-activity relationships of 2-amino-8- hydroxyadenines as orally active interferon inducing agents

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 24, 2003, Pages 5501-5508

  Kurimoto, Ayumu ^a   Ogino, Tetsuhiro ^a   Ichii, Shinji ^a   Isobe, Yoshiaki ^a   Tobe, Masanori ^a   Ogita, Haruhisa ^a   Takaku, Haruo ^a   Sajiki, Hironao ^b   Hirota, Kosaku ^b   Kawakami, Hajime ^a  

^a DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

^b GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 8 HYDROXYADENINE DERIVATIVE; 9 BENZYL 8 HYDROXY 2 [(2 METHOXYMETHYL)AMINO]ADENINE; ADENINE DERIVATIVE; CARBON; IMIQUIMOD; INTERFERON; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG SYNTHESIS; MALE; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

EID: 0344851553     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2003.09.032     Document Type: Article

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