Synthesis of 2-alkoxy-8-hydroxyadenylpeptides: Towards synthetic epitope-based vaccines

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 12, 2006, Pages 3258-3261

  Weterings, Jimmy J ^a   Khan, Selina ^b   van der Heden, Gerbrand J ^a   Drijfhout, Jan W ^b   Melief, Cornelis J M ^b   Overkleeft, Herman S ^a   van der Burg, Sjoerd H ^b   Ossendorp, Ferry ^b   van der Marel, Gijsbert A ^a   Filippov, Dmitri V ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Antigen presentation; Dendritic cells; Huisgen cycloaddition; Peptide synthesis; TLR 7

Indexed keywords

2 ALKOXY 8 HYDROXYADENYLPEPTIDE; EPITOPE; INTERLEUKIN 12; PEPTIDE DERIVATIVE; RESIN; UNCLASSIFIED DRUG; VACCINE;

ANTIGEN PRESENTATION; ARTICLE; CATALYSIS; CYCLOADDITION; CYTOKINE PRODUCTION; IMMUNOGENICITY; SOLID PHASE SYNTHESIS;

ADENINE; ANTIGEN PRESENTATION; DENDRITIC CELLS; EPITOPES; HISTOCOMPATIBILITY ANTIGENS CLASS I; INTERLEUKIN-12; MOLECULAR STRUCTURE; PEPTIDES; VACCINES;

EID: 33646187923     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.03.034     Document Type: Article

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