Repair-deficient 3-methyladenine DNA glycosylase homozygous mutant mouse cells have increased sensitivity to alkylation-induced chromosome damage and cell killing

EMBO Journal

Volumn 15, Issue 4, 1996, Pages 945-952

  Engelward, Bevin P ^a   Dreslin, Andrew ^a   Christensen, Julie ^b   Huszar, Dennis ^b,c   Kurahara, Carole ^b   Samson, Leona ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b GenPharm International   (United States)

^c MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

3 methyladenine; Chemotherapy; DNA alkylation repair; Gene targeting; Null embryonic stem cells

Indexed keywords

3 METHYLADENINE; ALKYLATING AGENT; CARMUSTINE; COMPLEMENTARY DNA; DNA GLYCOSYLTRANSFERASE; MITOMYCIN C;

ANIMAL CELL; ARTICLE; CELL KILLING; CHROMOSOME DAMAGE; CONTROLLED STUDY; CYTOTOXICITY; DNA ALKYLATION; DNA DAMAGE; DNA RECOMBINATION; DNA REPAIR; DNA REPLICATION; ENZYME ACTIVITY; HOMOZYGOTE; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEM CELL;

EID: 0030041960     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00429.x     Document Type: Article

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