Selectively N-protected enantiopure 2,5-disubstituted piperazines: Avoiding the pitfalls in solid-phase Fukuyama-Mitsunobu cyclizations

Chemistry - A European Journal

Volumn 15, Issue 12, 2009, Pages 2966-2978

  Ottesen, Lars K ^a   Olsen, Christian A ^a,b   Witt, Matthias ^c   Jaroszewski, Jerzy W ^a   Franzyk, Henrik ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c BRUKER DALTONIK GMBH   (Germany)

Author keywords

Aminolysis; Aziridines; Fukuyama Mitsunobu cyclization; Piperazines; Solid phase synthesis

Indexed keywords

ALDEHYDES; AMINATION; AMINES; AMINO ACIDS; AROMATIC HYDROCARBONS; CHEMICAL COMPOUNDS; GROUP TECHNOLOGY; METHANOL; MICROWAVES; ORGANIC ACIDS; RESINS; SYNTHESIS (CHEMICAL); UREA;

AMINOLYSIS; AZIRIDINES; FUKUYAMA-MITSUNOBU CYCLIZATION; PIPERAZINES; SOLID-PHASE SYNTHESIS;

CYCLIZATION;

AZIRIDINE DERIVATIVE; PIPERAZINE DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; COMBINATORIAL CHEMISTRY; CYCLIZATION; MICROWAVE RADIATION; STEREOISOMERISM; SYNTHESIS;

AZIRIDINES; COMBINATORIAL CHEMISTRY TECHNIQUES; CYCLIZATION; MICROWAVES; MOLECULAR STRUCTURE; PIPERAZINES; STEREOISOMERISM;

EID: 62349101581     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.200802044     Document Type: Article

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