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Volumn 180, Issue 4, 2008, Pages 2277-2293

Ultraconserved elements: Analyses of dosage sensitivity, motifs and boundaries

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CONSERVATION GENETICS; DNA RESPONSIVE ELEMENT; DNA SEQUENCE; GENE DELETION; GENE DUPLICATION; GENE EXPRESSION; GENE INSERTION; GENE SEQUENCE; HUMAN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 61849165014     PISSN: 00166731     EISSN: 00166731     Source Type: Journal    
DOI: 10.1534/genetics.108.096537     Document Type: Article
Times cited : (32)

References (67)
  • 1
    • 35448987034 scopus 로고    scopus 로고
    • Statistical information characterization of conserved non-coding elements in vertebrates
    • ABNIZOVA, I., K. WALTER, R. TE BOEKHORST, G. ELGAR and W. R. GILKS, 2007 Statistical information characterization of conserved non-coding elements in vertebrates. J. Bioinform. Comput. Biol. 5: 533-547.
    • (2007) J. Bioinform. Comput. Biol , vol.5 , pp. 533-547
    • ABNIZOVA, I.1    WALTER, K.2    TE BOEKHORST, R.3    ELGAR, G.4    GILKS, W.R.5
  • 2
    • 34548697503 scopus 로고    scopus 로고
    • Deletion of ultraconserved elements yields viable mice
    • AHITUV, N., Y. ZHU, A. VISEL, A. HOLT, V. AFZAL et al., 2007 Deletion of ultraconserved elements yields viable mice. PLoS Biol. 5: e234.
    • (2007) PLoS Biol , vol.5
    • AHITUV, N.1    ZHU, Y.2    VISEL, A.3    HOLT, A.4    AFZAL, V.5
  • 3
    • 33745373606 scopus 로고    scopus 로고
    • Primate segmental duplications: Crucibles of evolution, diversity and disease
    • BAILEY, J. A., and E. E. EICHLER, 2006 Primate segmental duplications: crucibles of evolution, diversity and disease. Nat. Rev. Genet. 7: 552-564.
    • (2006) Nat. Rev. Genet , vol.7 , pp. 552-564
    • BAILEY, J.A.1    EICHLER, E.E.2
  • 5
    • 34250632677 scopus 로고    scopus 로고
    • The gene balance hypothesis: From classical genetics to modern genomics
    • BIRCHLER, J. A., and R. A. VEITIA, 2007 The gene balance hypothesis: from classical genetics to modern genomics. Plant Cell 19: 395-402.
    • (2007) Plant Cell , vol.19 , pp. 395-402
    • BIRCHLER, J.A.1    VEITIA, R.A.2
  • 6
    • 3042740671 scopus 로고    scopus 로고
    • Comparative genomics at the vertebrate extremes
    • BOFFELLI, D., M. A. NOBREGA and E. M. RUBIN, 2004 Comparative genomics at the vertebrate extremes. Nat. Rev. Genet. 5: 456-465.
    • (2004) Nat. Rev. Genet , vol.5 , pp. 456-465
    • BOFFELLI, D.1    NOBREGA, M.A.2    RUBIN, E.M.3
  • 7
    • 34147151710 scopus 로고    scopus 로고
    • The strength of selection on ultraconserved elements in the human genome
    • CHEN, C. T., J. C. WANG and B. A. COHEN, 2007 The strength of selection on ultraconserved elements in the human genome. Am. J. Hum. Genet. 80: 692-704.
    • (2007) Am. J. Hum. Genet , vol.80 , pp. 692-704
    • CHEN, C.T.1    WANG, J.C.2    COHEN, B.A.3
  • 8
    • 0037837485 scopus 로고    scopus 로고
    • Genome-wide detection of segmental duplications and potential assembly errors in the human genome sequence
    • CHEUNG, J., X. ESTIVILL, R. KHAJA, J. R. MACDONALD, K. LAU et al., 2003 Genome-wide detection of segmental duplications and potential assembly errors in the human genome sequence. Genome Biol. 4: R25.
    • (2003) Genome Biol , vol.4
    • CHEUNG, J.1    ESTIVILL, X.2    KHAJA, R.3    MACDONALD, J.R.4    LAU, K.5
  • 9
    • 34347354302 scopus 로고    scopus 로고
    • Mutational and selective effects on copy-number variants in the human genome
    • COOPER, G. M., D. A. NICKERSON and E. E. EICHLER, 2007 Mutational and selective effects on copy-number variants in the human genome. Nat. Genet. 39: S22-S29.
    • (2007) Nat. Genet , vol.39
    • COOPER, G.M.1    NICKERSON, D.A.2    EICHLER, E.E.3
  • 10
    • 52949093111 scopus 로고    scopus 로고
    • Systematic assessment of copy number variant detection via genome-wide SNP genotyping
    • COOPER, G. M., T. ZERR, J. M. KIDD, E. E. EICHLER and D. A. NICKERSON, 2008 Systematic assessment of copy number variant detection via genome-wide SNP genotyping. Nat. Genet. 40: 1199-1203.
    • (2008) Nat. Genet , vol.40 , pp. 1199-1203
    • COOPER, G.M.1    ZERR, T.2    KIDD, J.M.3    EICHLER, E.E.4    NICKERSON, D.A.5
  • 11
    • 23744502709 scopus 로고    scopus 로고
    • A functional survey of the enhancer activity of conserved non-coding sequences from vertebrate Iroquois cluster gene deserts
    • DE LA CALLE-MUSTIENES, E., C. G. FEIJOO, M. MANZANARES, J. J. TENA, E. RODRIGUEZ-SEGUEL et al., 2005 A functional survey of the enhancer activity of conserved non-coding sequences from vertebrate Iroquois cluster gene deserts. Genome Res. 15: 1061-1072.
    • (2005) Genome Res , vol.15 , pp. 1061-1072
    • LA CALLE-MUSTIENES, D.E.1    FEIJOO, E.C.G.2    MANZANARES, M.3    TENA, J.J.4    RODRIGUEZ-SEGUEL, E.5
  • 12
    • 2442695243 scopus 로고    scopus 로고
    • Comparison of human chromosome 21 conserved nongenic sequences (CNGs) with the mouse and dog genomes shows that their selective constraint is independent of their genic environment
    • DERMITZAKIS, E. T., E. KIRKNESS, S. SCHWARZ, E. BIRNEY, A. REYMOND et al., 2004 Comparison of human chromosome 21 conserved nongenic sequences (CNGs) with the mouse and dog genomes shows that their selective constraint is independent of their genic environment. Genome Res. 14: 852-859.
    • (2004) Genome Res , vol.14 , pp. 852-859
    • DERMITZAKIS, E.T.1    KIRKNESS, E.2    SCHWARZ, S.3    BIRNEY, E.4    REYMOND, A.5
  • 13
    • 33749122708 scopus 로고    scopus 로고
    • Mammalian ultraconserved elements are strongly depleted among segmental duplications and copy number variants
    • DERTI, A., F. P. ROTH, G. M. CHURCH and C. T. WU, 2006 Mammalian ultraconserved elements are strongly depleted among segmental duplications and copy number variants. Nat. Genet. 38: 1216-1220.
    • (2006) Nat. Genet , vol.38 , pp. 1216-1220
    • DERTI, A.1    ROTH, F.P.2    CHURCH, G.M.3    WU, C.T.4
  • 14
    • 35748971743 scopus 로고    scopus 로고
    • Array CGH analysis of copy number variation identifies 1284 new genes variant in healthy white males: Implications for association studies of complex diseases
    • DE SMITH, A. J., A. TSALENKO, N. SAMPAS, A. SCHEFFER, N. A. YAMADA et al., 2007 Array CGH analysis of copy number variation identifies 1284 new genes variant in healthy white males: implications for association studies of complex diseases. Hum. Mol. Genet. 16: 2783-2794.
    • (2007) Hum. Mol. Genet , vol.16 , pp. 2783-2794
    • DE SMITH, A.J.1    TSALENKO, A.2    SAMPAS, N.3    SCHEFFER, A.4    YAMADA, N.A.5
  • 15
    • 31744448843 scopus 로고    scopus 로고
    • Conserved noncoding sequences are selectively constrained and not mutation cold spots
    • DRAKE, J. A., C. BIRD, J. NEMESH, D. J. THOMAS, C. NEWTON-CHEH et al., 2006 Conserved noncoding sequences are selectively constrained and not mutation cold spots. Nat. Genet. 38: 223-227.
    • (2006) Nat. Genet , vol.38 , pp. 223-227
    • DRAKE, J.A.1    BIRD, C.2    NEMESH, J.3    THOMAS, D.J.4    NEWTON-CHEH, C.5
  • 16
    • 0036957751 scopus 로고    scopus 로고
    • Transvection effects in Drosophila
    • DUNCAN, I. W., 2002 Transvection effects in Drosophila. Annu. Rev. Genet. 36: 521-556.
    • (2002) Annu. Rev. Genet , vol.36 , pp. 521-556
    • DUNCAN, I.W.1
  • 17
    • 33744804277 scopus 로고    scopus 로고
    • The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator
    • FENG, J., C. BI, B. S. CLARK, R. MADY, P. SHAH et al., 2006 The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator. Genes Dev. 20: 1470-1484.
    • (2006) Genes Dev , vol.20 , pp. 1470-1484
    • FENG, J.1    BI, C.2    CLARK, B.S.3    MADY, R.4    SHAH, P.5
  • 18
    • 33645833857 scopus 로고    scopus 로고
    • Conservation of RET regulatory function from human to zebrafish without sequence similarity
    • FISHER, S., E. A. GRICE, R. M. VINTON, S. L. BESSLING and A. S. MCCALLION, 2006 Conservation of RET regulatory function from human to zebrafish without sequence similarity. Science 312: 276-279.
    • (2006) Science , vol.312 , pp. 276-279
    • FISHER, S.1    GRICE, E.A.2    VINTON, R.M.3    BESSLING, S.L.4    MCCALLION, A.S.5
  • 19
    • 0032573434 scopus 로고    scopus 로고
    • Engrailed homeodomain-DNA complex at 2.2 A resolution: A detailed view of the interface and comparison with other engrailed structures
    • FRAENKEL, E., M. A. ROULD, K. A. CHAMBERS and C. O. PABO, 1998 Engrailed homeodomain-DNA complex at 2.2 A resolution: a detailed view of the interface and comparison with other engrailed structures. J. Mol. Biol. 284: 351-361.
    • (1998) J. Mol. Biol , vol.284 , pp. 351-361
    • FRAENKEL, E.1    ROULD, M.A.2    CHAMBERS, K.A.3    PABO, C.O.4
  • 20
    • 33646252228 scopus 로고    scopus 로고
    • Genomic data analysis using DNA structure: An analysis of conserved nongenic sequences and ultraconserved elements
    • GARDINER, E. J., L. HIRONS, C. A. HUNTER and P. WILLETT, 2006 Genomic data analysis using DNA structure: an analysis of conserved nongenic sequences and ultraconserved elements. J. Chem. Inf. Model. 46: 753-761.
    • (2006) J. Chem. Inf. Model , vol.46 , pp. 753-761
    • GARDINER, E.J.1    HIRONS, L.2    HUNTER, C.A.3    WILLETT, P.4
  • 21
    • 1642286026 scopus 로고    scopus 로고
    • Plants, pairing and phenotypes: Two's company?
    • GRANT-DOWNTON, R. T., and H. G. DICKINSON, 2004 Plants, pairing and phenotypes: Two's company? Trends Genet. 20: 188-195.
    • (2004) Trends Genet , vol.20 , pp. 188-195
    • GRANT-DOWNTON, R.T.1    DICKINSON, H.G.2
  • 22
    • 10644283823 scopus 로고    scopus 로고
    • Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution
    • INTERNATIONAL CHICKEN GENOME SEQUENCING CONSORTIUM
    • INTERNATIONAL CHICKEN GENOME SEQUENCING CONSORTIUM, 2004 Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature 432: 695-716.
    • (2004) Nature , vol.432 , pp. 695-716
  • 23
    • 79959524146 scopus 로고    scopus 로고
    • A haplotype map of the human genome
    • INTERNATIONAL HAPMAP CONSORTIUM
    • INTERNATIONAL HAPMAP CONSORTIUM, 2005 A haplotype map of the human genome. Nature 437: 1299-1320.
    • (2005) Nature , vol.437 , pp. 1299-1320
  • 24
    • 39749197456 scopus 로고    scopus 로고
    • Genotype, haplotype and copy-number variation in worldwide human populations
    • JAKOBSSON, M., S. W. SCHOLZ, P. SCHEET, J. R. GIBBS, J. M. VANLIERE et al., 2008 Genotype, haplotype and copy-number variation in worldwide human populations. Nature 451: 998-1003.
    • (2008) Nature , vol.451 , pp. 998-1003
    • JAKOBSSON, M.1    SCHOLZ, S.W.2    SCHEET, P.3    GIBBS, J.R.4    VANLIERE, J.M.5
  • 25
    • 34548131708 scopus 로고    scopus 로고
    • Human genome ultraconserved elements are ultraselected
    • KATZMAN, S., A. D. KERN, G. BEJERANO, G. FEWELL, L. FULTON et al., 2007 Human genome ultraconserved elements are ultraselected. Science 317: 915.
    • (2007) Science , vol.317 , pp. 915
    • KATZMAN, S.1    KERN, A.D.2    BEJERANO, G.3    FEWELL, G.4    FULTON, L.5
  • 26
    • 0033832676 scopus 로고    scopus 로고
    • KENT, W. J., and A. M. ZAHLER, 2000 Conservation, regulation, synteny, and introns in a large-scale C. briggsae-C. elegans genomic alignment. Genome Res. 10: 1115-1125.
    • KENT, W. J., and A. M. ZAHLER, 2000 Conservation, regulation, synteny, and introns in a large-scale C. briggsae-C. elegans genomic alignment. Genome Res. 10: 1115-1125.
  • 27
    • 43049143055 scopus 로고    scopus 로고
    • Mapping and sequencing of structural variation from eight human genomes
    • KIDD, J. M., G. M. COOPER, W. F. DONAHUE, H. S. HAYDEN, N. SAMPAS et al., 2008 Mapping and sequencing of structural variation from eight human genomes. Nature 453: 56-64.
    • (2008) Nature , vol.453 , pp. 56-64
    • KIDD, J.M.1    COOPER, G.M.2    DONAHUE, W.F.3    HAYDEN, H.S.4    SAMPAS, N.5
  • 28
    • 35348988679 scopus 로고    scopus 로고
    • Paired-end mapping reveals extensive structural variation in the human genome
    • KORBEL, J. O., A. E. URBAN, J. P. AFFOURTIT, B. GODWIN, F. GRUBERT et al., 2007 Paired-end mapping reveals extensive structural variation in the human genome. Science 318: 420-426.
    • (2007) Science , vol.318 , pp. 420-426
    • KORBEL, J.O.1    URBAN, A.E.2    AFFOURTIT, J.P.3    GODWIN, B.4    GRUBERT, F.5
  • 29
    • 34247330971 scopus 로고    scopus 로고
    • Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements
    • LAREAU, L. F., M. INADA, R. E. GREEN, J. C. WENGROD and S. E. BRENNER, 2007 Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements. Nature 446: 926-929.
    • (2007) Nature , vol.446 , pp. 926-929
    • LAREAU, L.F.1    INADA, M.2    GREEN, R.E.3    WENGROD, J.C.4    BRENNER, S.E.5
  • 30
    • 33845742990 scopus 로고    scopus 로고
    • Enhancer-promoter communication at the yellow gene of Drosophila melanogaster: Diverse promoters participate in and regulate trans interactions
    • LEE, A. M., and C. T. WU, 2006 Enhancer-promoter communication at the yellow gene of Drosophila melanogaster: diverse promoters participate in and regulate trans interactions. Genetics 174: 1867-1880.
    • (2006) Genetics , vol.174 , pp. 1867-1880
    • LEE, A.M.1    WU, C.T.2
  • 31
    • 40149095913 scopus 로고    scopus 로고
    • Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm
    • LI, X. Y., S. MACARTHUR, R. BOURGON, D. NIX, D. A. POLLARD et al., 2008 Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm. PLoS Biol. 6: e27.
    • (2008) PLoS Biol , vol.6
    • LI, X.Y.1    MACARTHUR, S.2    BOURGON, R.3    NIX, D.4    POLLARD, D.A.5
  • 32
    • 0036324753 scopus 로고    scopus 로고
    • An algorithm for finding protein-DNA binding sites with applications to chromatin-immunoprecipitation microarray experiments
    • LIU, X. S., D. L. BRUTLAG and J. S. LIU, 2002 An algorithm for finding protein-DNA binding sites with applications to chromatin-immunoprecipitation microarray experiments. Nat. Biotechnol. 20: 835-839.
    • (2002) Nat. Biotechnol , vol.20 , pp. 835-839
    • LIU, X.S.1    BRUTLAG, D.L.2    LIU, J.S.3
  • 34
    • 52949141845 scopus 로고    scopus 로고
    • Integrated detection and population-genetic analysis of SNPs and copy number variation
    • MCCARROLL, S. A., F. G. KURUVILLA, J. M. KORN, S. CAWLEY, J. NEMESH et al., 2008 Integrated detection and population-genetic analysis of SNPs and copy number variation. Nat. Genet. 40: 1166-1174.
    • (2008) Nat. Genet , vol.40 , pp. 1166-1174
    • MCCARROLL, S.A.1    KURUVILLA, F.G.2    KORN, J.M.3    CAWLEY, S.4    NEMESH, J.5
  • 35
    • 33645519275 scopus 로고    scopus 로고
    • Ancient duplicated conserved noncoding elements in vertebrates: A genomic and functional analysis
    • MCEWEN, G. K., A. WOOLFE, D. GOODE, T. VAVOURI, H. CALLAWAY et al., 2006 Ancient duplicated conserved noncoding elements in vertebrates: a genomic and functional analysis. Genome Res. 16: 451-465.
    • (2006) Genome Res , vol.16 , pp. 451-465
    • MCEWEN, G.K.1    WOOLFE, A.2    GOODE, D.3    VAVOURI, T.4    CALLAWAY, H.5
  • 36
    • 39049147650 scopus 로고    scopus 로고
    • Metrics of sequence constraint overlook regulatory sequences in an exhaustive analysis at phox2b
    • MCGAUGHEY, D. M., R. M. VINTON, J. HUYNH, A. AL-SAIF, M. A. BEER et al., 2008 Metrics of sequence constraint overlook regulatory sequences in an exhaustive analysis at phox2b. Genome Res. 18: 252-260.
    • (2008) Genome Res , vol.18 , pp. 252-260
    • MCGAUGHEY, D.M.1    VINTON, R.M.2    HUYNH, J.3    AL-SAIF, A.4    BEER, M.A.5
  • 37
    • 1542328265 scopus 로고    scopus 로고
    • Homologous pairing and chromosome dynamics in meiosis and mitosis
    • MCKEE, B. D., 2004 Homologous pairing and chromosome dynamics in meiosis and mitosis. Biochim. Biophys. Acta 1677: 165-180.
    • (2004) Biochim. Biophys. Acta , vol.1677 , pp. 165-180
    • MCKEE, B.D.1
  • 38
    • 33748271469 scopus 로고    scopus 로고
    • An initial map of insertion and deletion (INDEL) variation in the human genome
    • MILLS, R. E., C. T. LUTTIG, C. E. LARKINS, A. BEAUCHAMP, C. TSUI et al., 2006 An initial map of insertion and deletion (INDEL) variation in the human genome. Genome Res. 16: 1182-1190.
    • (2006) Genome Res , vol.16 , pp. 1182-1190
    • MILLS, R.E.1    LUTTIG, C.T.2    LARKINS, C.E.3    BEAUCHAMP, A.4    TSUI, C.5
  • 39
    • 3042681300 scopus 로고    scopus 로고
    • Information content and complexity in the high-order organization of DNA
    • MINSKY, A., 2004 Information content and complexity in the high-order organization of DNA. Annu. Rev. Biophys. Biomol. Struct. 33: 317-342.
    • (2004) Annu. Rev. Biophys. Biomol. Struct , vol.33 , pp. 317-342
    • MINSKY, A.1
  • 41
    • 33947305594 scopus 로고    scopus 로고
    • Ultraconserved elements are associated with homeostatic control of splicing regulators by alternative splicing and non-sense-mediated decay
    • NI, J. Z., L. GRATE, J. P. DONOHUE, C. PRESTON, N. NOBIDA et al., 2007 Ultraconserved elements are associated with homeostatic control of splicing regulators by alternative splicing and non-sense-mediated decay. Genes Dev. 21: 708-718.
    • (2007) Genes Dev , vol.21 , pp. 708-718
    • NI, J.Z.1    GRATE, L.2    DONOHUE, J.P.3    PRESTON, C.4    NOBIDA, N.5
  • 42
    • 34547459097 scopus 로고    scopus 로고
    • Ultraconserved non-coding sequence element controls a subset of spatiotemporal GLI3 expression
    • PAPARIDIS, Z., A. A. ABBASI, S. MALIK, D. K. GOODE, H. CALLAWAY et al., 2007 Ultraconserved non-coding sequence element controls a subset of spatiotemporal GLI3 expression. Dev. Growth Differ. 49: 543-553.
    • (2007) Dev. Growth Differ , vol.49 , pp. 543-553
    • PAPARIDIS, Z.1    ABBASI, A.A.2    MALIK, S.3    GOODE, D.K.4    CALLAWAY, H.5
  • 43
    • 3242884167 scopus 로고    scopus 로고
    • Weeder web: Discovery of transcription factor binding sites in a set of sequences from co-regulated genes
    • PAVESI, G., P. MEREGHETTI, G. MAURI and G. PESOLE, 2004 Weeder web: discovery of transcription factor binding sites in a set of sequences from co-regulated genes. Nucleic Acids Res. 32: W199-W203.
    • (2004) Nucleic Acids Res , vol.32
    • PAVESI, G.1    MEREGHETTI, P.2    MAURI, G.3    PESOLE, G.4
  • 44
    • 33751316959 scopus 로고    scopus 로고
    • In vivo enhancer analysis of human conserved non-coding sequences
    • PENNACCHIO, L. A., N. AHITUV, A. M. MOSES, S. PRABHAKAR, M. A. NOBREGA et al., 2006 In vivo enhancer analysis of human conserved non-coding sequences. Nature 444: 499-502.
    • (2006) Nature , vol.444 , pp. 499-502
    • PENNACCHIO, L.A.1    AHITUV, N.2    MOSES, A.M.3    PRABHAKAR, S.4    NOBREGA, M.A.5
  • 46
    • 38449122025 scopus 로고    scopus 로고
    • PINTO, D., C. MARSHALL, L. FEUK and S. W. SCHERER, 2007 Copynumber variation in control population cohorts. Hum. Mol. Genet. 16 (Spec. no. 2): R168-R173.
    • PINTO, D., C. MARSHALL, L. FEUK and S. W. SCHERER, 2007 Copynumber variation in control population cohorts. Hum. Mol. Genet. 16 (Spec. no. 2): R168-R173.
  • 47
    • 44349089659 scopus 로고    scopus 로고
    • The words of the regulatory code are arranged in a variable manner in highly conserved enhancers
    • RASTEGAR, S., I. HESS, T. DICKMEIS, J. C. NICOD, R. ERTZER et al., 2008 The words of the regulatory code are arranged in a variable manner in highly conserved enhancers. Dev. Biol. 318: 366-377.
    • (2008) Dev. Biol , vol.318 , pp. 366-377
    • RASTEGAR, S.1    HESS, I.2    DICKMEIS, T.3    NICOD, J.C.4    ERTZER, R.5
  • 48
    • 33751329250 scopus 로고    scopus 로고
    • Global variation in copy number in the human genome
    • REDON, R., S. ISHIKAWA, K. R. FITCH, L. FEUK, G. H. PERRY et al., 2006 Global variation in copy number in the human genome. Nature 444: 444-454.
    • (2006) Nature , vol.444 , pp. 444-454
    • REDON, R.1    ISHIKAWA, S.2    FITCH, K.R.3    FEUK, L.4    PERRY, G.H.5
  • 49
    • 34347348166 scopus 로고    scopus 로고
    • Challenges and standards in integrating surveys of structural variation
    • SCHERER, S. W., C. LEE, E. BIRNEY, D. M. ALTSHULER, E. E. EICHLER et al., 2007 Challenges and standards in integrating surveys of structural variation. Nat. Genet. 39: S7-S15.
    • (2007) Nat. Genet , vol.39
    • SCHERER, S.W.1    LEE, C.2    BIRNEY, E.3    ALTSHULER, D.M.4    EICHLER, E.E.5
  • 50
    • 27944499451 scopus 로고    scopus 로고
    • An iterative statistical approach to the identification of protein phosphorylation motifs from large-scale data sets
    • SCHWARTZ, D., and S. P. GYGI, 2005 An iterative statistical approach to the identification of protein phosphorylation motifs from large-scale data sets. Nat. Biotechnol. 23: 1391-1398.
    • (2005) Nat. Biotechnol , vol.23 , pp. 1391-1398
    • SCHWARTZ, D.1    GYGI, S.P.2
  • 52
    • 7244247384 scopus 로고    scopus 로고
    • Shotgun sequence assembly and recent segmental duplications within the human genome
    • SHE, X., Z. JIANG, R. A. CLARK, G. LIU, Z. CHENG et al., 2004 Shotgun sequence assembly and recent segmental duplications within the human genome. Nature 431: 927-930.
    • (2004) Nature , vol.431 , pp. 927-930
    • SHE, X.1    JIANG, Z.2    CLARK, R.A.3    LIU, G.4    CHENG, Z.5
  • 53
    • 23744458086 scopus 로고    scopus 로고
    • SIEPEL, A., G. BEJERANO, J. S. PEDERSEN, A. S. HINRICHS, M. HOU et al., 2005 Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes. Genome Res. 15: 1034-1050.
    • SIEPEL, A., G. BEJERANO, J. S. PEDERSEN, A. S. HINRICHS, M. HOU et al., 2005 Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes. Genome Res. 15: 1034-1050.
  • 54
    • 33846531959 scopus 로고    scopus 로고
    • Genome-wide SNP assay reveals structural genomic variation, extended homozygosity and cell-line induced alterations in normal individuals
    • SIMON-SANCHEZ, J., S. SCHOLZ, H. C. FUNG, M. MATARIN, D. HERNANDEZ et al., 2007 Genome-wide SNP assay reveals structural genomic variation, extended homozygosity and cell-line induced alterations in normal individuals. Hum. Mol. Genet. 16: 1-14.
    • (2007) Hum. Mol. Genet , vol.16 , pp. 1-14
    • SIMON-SANCHEZ, J.1    SCHOLZ, S.2    FUNG, H.C.3    MATARIN, M.4    HERNANDEZ, D.5
  • 55
    • 38949097100 scopus 로고    scopus 로고
    • Largescale appearance of ultraconserved elements in tetrapod genomes and slowdown of the molecular clock
    • STEPHEN, S., M. PHEASANT, I. V. MAKUNIN and J. S. MATTICK, 2008 Largescale appearance of ultraconserved elements in tetrapod genomes and slowdown of the molecular clock. Mol. Biol. Evol. 25: 402-408.
    • (2008) Mol. Biol. Evol , vol.25 , pp. 402-408
    • STEPHEN, S.1    PHEASANT, M.2    MAKUNIN, I.V.3    MATTICK, J.S.4
  • 56
    • 34447500684 scopus 로고    scopus 로고
    • Parallel evolution of conserved non-coding elements that target a common set of developmental regulatory genes from worms to humans
    • VAVOURI, T., K. WALTER, W. R. GILKS, B. LEHNER and G. ELGAR, 2007 Parallel evolution of conserved non-coding elements that target a common set of developmental regulatory genes from worms to humans. Genome Biol. 8: R15.
    • (2007) Genome Biol , vol.8
    • VAVOURI, T.1    WALTER, K.2    GILKS, W.R.3    LEHNER, B.4    ELGAR, G.5
  • 57
    • 38649123306 scopus 로고    scopus 로고
    • Ultraconservation identifies a small subset of extremely constrained developmental enhancers
    • VISEL, A., S. PRABHAKAR, J. A. AKIYAMA, M. SHOUKRY, K. D. LEWIS et al., 2008 Ultraconservation identifies a small subset of extremely constrained developmental enhancers. Nat. Genet. 40: 158-160.
    • (2008) Nat. Genet , vol.40 , pp. 158-160
    • VISEL, A.1    PRABHAKAR, S.2    AKIYAMA, J.A.3    SHOUKRY, M.4    LEWIS, K.D.5
  • 58
    • 22144494134 scopus 로고    scopus 로고
    • Striking nucleotide frequency pattern at the borders of highly conserved vertebrate non-coding sequences
    • WALTER, K., I. ABNIZOVA, G. ELGAR and W. R. GILKS, 2005 Striking nucleotide frequency pattern at the borders of highly conserved vertebrate non-coding sequences. Trends Genet. 21: 436-440.
    • (2005) Trends Genet , vol.21 , pp. 436-440
    • WALTER, K.1    ABNIZOVA, I.2    ELGAR, G.3    GILKS, W.R.4
  • 59
    • 35948984173 scopus 로고    scopus 로고
    • PennCNV: An integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data
    • WANG, K., M. LI, D. HADLEY, R. LIU, J. GLESSNER et al., 2007 PennCNV: an integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data. Genome Res. 17: 1665-1674.
    • (2007) Genome Res , vol.17 , pp. 1665-1674
    • WANG, K.1    LI, M.2    HADLEY, D.3    LIU, R.4    GLESSNER, J.5
  • 60
    • 43449123631 scopus 로고    scopus 로고
    • Genome analysis of the platypus reveals unique signatures of evolution
    • WARREN, W. C., L. W. HILLIER, J. A. MARSHALL GRAVES, E. BIRNEY, C. P. PONTING et al., 2008 Genome analysis of the platypus reveals unique signatures of evolution. Nature 453: 175-183.
    • (2008) Nature , vol.453 , pp. 175-183
    • WARREN, W.C.1    HILLIER, L.W.2    MARSHALL GRAVES, J.A.3    BIRNEY, E.4    PONTING, C.P.5
  • 61
    • 33846006596 scopus 로고    scopus 로고
    • A comprehensive analysis of common copy-number variations in the human genome
    • WONG, K. K., R. J. DELEEUW, N. S. DOSANJH, L. R. KIMM, Z. CHENG et al., 2007 A comprehensive analysis of common copy-number variations in the human genome. Am. J. Hum. Genet. 80: 91-104.
    • (2007) Am. J. Hum. Genet , vol.80 , pp. 91-104
    • WONG, K.K.1    DELEEUW, R.J.2    DOSANJH, N.S.3    KIMM, L.R.4    CHENG, Z.5
  • 62
    • 20044366725 scopus 로고    scopus 로고
    • Highly conserved non-coding sequences are associated with vertebrate development
    • WOOLFE, A., M. GOODSON, D. K. GOODE, P. SNELL, G. K. MCEWEN et al., 2005 Highly conserved non-coding sequences are associated with vertebrate development. PLoS Biol. 3: e7.
    • (2005) PLoS Biol , vol.3
    • WOOLFE, A.1    GOODSON, M.2    GOODE, D.K.3    SNELL, P.4    MCEWEN, G.K.5
  • 63
    • 0033118341 scopus 로고    scopus 로고
    • Transvection and other homology effects
    • WU, C. T., and J. R. MORRIS, 1999 Transvection and other homology effects. Curr. Opin. Genet. Dev. 9: 237-246.
    • (1999) Curr. Opin. Genet. Dev , vol.9 , pp. 237-246
    • WU, C.T.1    MORRIS, J.R.2
  • 64
    • 34249848791 scopus 로고    scopus 로고
    • Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites
    • XIE, X., T. S. MIKKELSEN, A. GNIRKE, K. LINDBLAD-TOH, M. KELLIS et al., 2007 Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites. Proc. Natl. Acad. Sci. USA 104: 7145-7150.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 7145-7150
    • XIE, X.1    MIKKELSEN, T.S.2    GNIRKE, A.3    LINDBLAD-TOH, K.4    KELLIS, M.5
  • 66
    • 33645967473 scopus 로고    scopus 로고
    • From early homologue recognition to synaptonemal complex formation
    • ZICKLER, D., 2006 From early homologue recognition to synaptonemal complex formation. Chromosoma 115: 158-174.
    • (2006) Chromosoma , vol.115 , pp. 158-174
    • ZICKLER, D.1
  • 67
    • 35448992970 scopus 로고    scopus 로고
    • Germ-line DNA copy number variation frequencies in a large North American population
    • ZOGOPOULOS, G., K. C. HA, F. NAQIB, S. MOORE, H. KIM et al., 2007 Germ-line DNA copy number variation frequencies in a large North American population. Hum. Genet. 122: 345-353.
    • (2007) Hum. Genet , vol.122 , pp. 345-353
    • ZOGOPOULOS, G.1    HA, K.C.2    NAQIB, F.3    MOORE, S.4    KIM, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.