-
1
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
The Huntington's Disease Collaborative Research Group
-
The Huntington's Disease Collaborative Research Group (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell, 72, 971-983.
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
2
-
-
0024311533
-
Nutritional evaluation of Huntington disease patients
-
Morales, L.M., Estevez, J., Suarez, H., Villalobos, R., Chacin de Bonilla, L. and Bonilla, E. (1989) Nutritional evaluation of Huntington disease patients. Am. J Clin. Nutr., 50, 145-150.
-
(1989)
Am. J Clin. Nutr
, vol.50
, pp. 145-150
-
-
Morales, L.M.1
Estevez, J.2
Suarez, H.3
Villalobos, R.4
Chacin de Bonilla, L.5
Bonilla, E.6
-
3
-
-
1242338792
-
Assessment of the nutrition status of patients with Huntington's disease
-
Trejo, A., Tarrats, R.M., Alonso, M.E., Boll, M.C., Ochoa, A. and Velasquez, L. (2004) Assessment of the nutrition status of patients with Huntington's disease. Nutrition, 20, 192-196.
-
(2004)
Nutrition
, vol.20
, pp. 192-196
-
-
Trejo, A.1
Tarrats, R.M.2
Alonso, M.E.3
Boll, M.C.4
Ochoa, A.5
Velasquez, L.6
-
4
-
-
0021794441
-
An anthropometric assessment of Huntington's disease patients and families
-
Fatter, L.A. and Meaney, F.J. (1985) An anthropometric assessment of Huntington's disease patients and families. Am. J. Phys. Anthropol. 67, 185-194.
-
(1985)
Am. J. Phys. Anthropol
, vol.67
, pp. 185-194
-
-
Fatter, L.A.1
Meaney, F.J.2
-
5
-
-
0019796509
-
Body weight and dietary factors in Huntington's disease patients compared with matched controls
-
Sanberg, P.R., Fibiger, H.C. and Mark, R.F. (1981) Body weight and dietary factors in Huntington's disease patients compared with matched controls. Med. J. Aust., 1, 407-409.
-
(1981)
Med. J. Aust
, vol.1
, pp. 407-409
-
-
Sanberg, P.R.1
Fibiger, H.C.2
Mark, R.F.3
-
6
-
-
0026332133
-
Factors associated with slow progression in Huntington's disease
-
Myers, R.H., Sax, D.S., Koroshetz, W.J., Mastromauro, C., Cupples, L.A., Kiely, D.K., Pettengill, F.K. and Bird, E.D. (1991) Factors associated with slow progression in Huntington's disease. Arch. Neurol., 48, 800-804.
-
(1991)
Arch. Neurol
, vol.48
, pp. 800-804
-
-
Myers, R.H.1
Sax, D.S.2
Koroshetz, W.J.3
Mastromauro, C.4
Cupples, L.A.5
Kiely, D.K.6
Pettengill, F.K.7
Bird, E.D.8
-
7
-
-
84991386183
-
Weight loss in Huntington's disease
-
Stoy, N. and McKay, E. (2000) Weight loss in Huntington's disease. Ann. Neurol., 48, 130-131.
-
(2000)
Ann. Neurol
, vol.48
, pp. 130-131
-
-
Stoy, N.1
McKay, E.2
-
8
-
-
0037069280
-
Weight loss in early stage of Huntington's disease
-
Djousse, L., Knowlton, B., Cupples, L.A., Marder, K., Shoulson, I. and Myers, R.H. (2002) Weight loss in early stage of Huntington's disease. Neurol., 59, 1325-1330.
-
(2002)
Neurol
, vol.59
, pp. 1325-1330
-
-
Djousse, L.1
Knowlton, B.2
Cupples, L.A.3
Marder, K.4
Shoulson, I.5
Myers, R.H.6
-
9
-
-
33748931457
-
Central nervous system control of food intake and body weight
-
Morton, G.J., Cummings, D.E., Baskin, D.G., Barsh, G.S. and Scwartz, M.W. (2006) Central nervous system control of food intake and body weight. Nature, 443, 289-295.
-
(2006)
Nature
, vol.443
, pp. 289-295
-
-
Morton, G.J.1
Cummings, D.E.2
Baskin, D.G.3
Barsh, G.S.4
Scwartz, M.W.5
-
10
-
-
33747602312
-
Hypothalainic-endocrine aspects in Huntington's disease
-
Petersen, A. and Bjorkqvist, M. (2006) Hypothalainic-endocrine aspects in Huntington's disease. Eur. J. Neurosci., 24, 961-967.
-
(2006)
Eur. J. Neurosci
, vol.24
, pp. 961-967
-
-
Petersen, A.1
Bjorkqvist, M.2
-
11
-
-
16044373842
-
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
Mangiarini, L., Sathasivam, K., Seller, M., Cozens, B., Harper, A., Hetherington, C., Lawton, M., Trottier, Y., Lehrach, H., Davies, S.W. et al. (1996) Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell, 87, 493-506.
-
(1996)
Cell
, vol.87
, pp. 493-506
-
-
Mangiarini, L.1
Sathasivam, K.2
Seller, M.3
Cozens, B.4
Harper, A.5
Hetherington, C.6
Lawton, M.7
Trottier, Y.8
Lehrach, H.9
Davies, S.W.10
-
12
-
-
0035862874
-
Abnormalities for the functioning of adipocytes from R6/2 mice that are transgenic for the Huntington's disease mutation
-
Fain, J.N., Del Mar,.N.A., Meade, C.A., Reiner, A. and Goldowitz, D. (2001) Abnormalities for the functioning of adipocytes from R6/2 mice that are transgenic for the Huntington's disease mutation. Hum. Mol. Genet., 10, 145-152.
-
(2001)
Hum. Mol. Genet
, vol.10
, pp. 145-152
-
-
Fain, J.N.1
Del Mar, N.A.2
Meade, C.A.3
Reiner, A.4
Goldowitz, D.5
-
13
-
-
33750437278
-
Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration
-
Weydt, P., Pinedd, V.V., Torrence, A.E., Libby, R.T., Satterfield, T.F., Lazarowski, E.R., Gilbert, M.L., Morton, G.J., Bammler, T.K., Strand, A.D. et al. (2006) Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration. Cell Metab., 4, 349-362.
-
(2006)
Cell Metab
, vol.4
, pp. 349-362
-
-
Weydt, P.1
Pinedd, V.V.2
Torrence, A.E.3
Libby, R.T.4
Satterfield, T.F.5
Lazarowski, E.R.6
Gilbert, M.L.7
Morton, G.J.8
Bammler, T.K.9
Strand, A.D.10
-
14
-
-
0037101835
-
Dysregulation of gene expression in the R6/2 model of polyglutamine disease: Parallel changes in muscle and brain
-
Luthi-Carter, R., Hanson, S.A., Strand, A.D., Bergstrom, D.A., Chun, W., Peters, N.L., Woods, A.M., Chan, E.Y., Kooperberg, C., Krainc, D. et al. (2002) Dysregulation of gene expression in the R6/2 model of polyglutamine disease: Parallel changes in muscle and brain. Hum. Mol. Genet., 11, 1911-1126.
-
(2002)
Hum. Mol. Genet
, vol.11
, pp. 1911-1126
-
-
Luthi-Carter, R.1
Hanson, S.A.2
Strand, A.D.3
Bergstrom, D.A.4
Chun, W.5
Peters, N.L.6
Woods, A.M.7
Chan, E.Y.8
Kooperberg, C.9
Krainc, D.10
-
15
-
-
25844526181
-
Gene expression in Huntington's disease skeletal muscle: A potential biomarker
-
Strand, A.D., Aragaki, A.K., Shaw, D., Bird, T., Holton, J., Turner, C., Tapscott, S.J., Tabrizi, S.J., Schapira, A.H., Kooperberg, C. et al. (2005) Gene expression in Huntington's disease skeletal muscle: A potential biomarker. Hum. Mol. Genet., 14, 1863-1876.
-
(2005)
Hum. Mol. Genet
, vol.14
, pp. 1863-1876
-
-
Strand, A.D.1
Aragaki, A.K.2
Shaw, D.3
Bird, T.4
Holton, J.5
Turner, C.6
Tapscott, S.J.7
Tabrizi, S.J.8
Schapira, A.H.9
Kooperberg, C.10
-
16
-
-
10844273236
-
Progressive abnormalities in skeletal muscle and neuromuscular junctions of transgenic mice expressing the Huntington's disease mutation
-
Ribchester, R.R., Thomson, D., Wood, N.I., Hinks, T., GillingWater, T.H., Wishart, T.M., Court, F.A. and Morton, A.J. (2004) Progressive abnormalities in skeletal muscle and neuromuscular junctions of transgenic mice expressing the Huntington's disease mutation. Eur. J. Neurosci., 20, 3092-3114.
-
(2004)
Eur. J. Neurosci
, vol.20
, pp. 3092-3114
-
-
Ribchester, R.R.1
Thomson, D.2
Wood, N.I.3
Hinks, T.4
GillingWater, T.H.5
Wishart, T.M.6
Court, F.A.7
Morton, A.J.8
-
17
-
-
20044392282
-
The R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient beta-cell mass and exocytosis
-
Bjorkqvist, M., Fex, M., Renstrom, E., Wierup, N., Petersen, A., Gil, J., Bacos, K., Popovic, N., Li, J.Y., Sundler, F. et al. (2005) The R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient beta-cell mass and exocytosis. Hum. Mol. Genet., 14, 565-574.
-
(2005)
Hum. Mol. Genet
, vol.14
, pp. 565-574
-
-
Bjorkqvist, M.1
Fex, M.2
Renstrom, E.3
Wierup, N.4
Petersen, A.5
Gil, J.6
Bacos, K.7
Popovic, N.8
Li, J.Y.9
Sundler, F.10
-
18
-
-
0037002444
-
Huntington's disease of the endocrine pancreas: Insulin deficiency and diabetes mellitus due to impaired insulin gene expression
-
Andreassen, O.A., Dedeoglu, A., Stanojevic, V., Hughes, D.B., Browne, S.E., Leech, C.A., Ferrante, R.J., Habener, J.F., Beal, M.F. and Thomas, M.K. (2002) Huntington's disease of the endocrine pancreas: Insulin deficiency and diabetes mellitus due to impaired insulin gene expression. Neurobiol. Dis., 11, 410-424.
-
(2002)
Neurobiol. Dis
, vol.11
, pp. 410-424
-
-
Andreassen, O.A.1
Dedeoglu, A.2
Stanojevic, V.3
Hughes, D.B.4
Browne, S.E.5
Leech, C.A.6
Ferrante, R.J.7
Habener, J.F.8
Beal, M.F.9
Thomas, M.K.10
-
19
-
-
0033009587
-
-
Hurlbert, M.S., Zhou, W., Wasmeier, C., Kaddis, F.G., Hutton, J.C. and Freed, C.R. ([999) Mice transgenic for an expanded CAG repeat in the Huntington's disease gene develop diabetes. Diabetes, 48, 649-651.
-
Hurlbert, M.S., Zhou, W., Wasmeier, C., Kaddis, F.G., Hutton, J.C. and Freed, C.R. ([999) Mice transgenic for an expanded CAG repeat in the Huntington's disease gene develop diabetes. Diabetes, 48, 649-651.
-
-
-
-
20
-
-
41349100027
-
The metabolic profile of early Huntington's disease - a combined human and transgenic mouse study
-
Goodman, A.O., Murgatroyd, P.R., Medina-Gomez, G., Wood, N.I., Finer, N., Vidal-Puig, A.J., Morton, A.J. and Barker, R.A. (2008) The metabolic profile of early Huntington's disease - a combined human and transgenic mouse study. Exp. Neurol., 210, 691-698.
-
(2008)
Exp. Neurol
, vol.210
, pp. 691-698
-
-
Goodman, A.O.1
Murgatroyd, P.R.2
Medina-Gomez, G.3
Wood, N.I.4
Finer, N.5
Vidal-Puig, A.J.6
Morton, A.J.7
Barker, R.A.8
-
21
-
-
36549050391
-
Increased metabolism in the R6/2 mouse model of Huntington's disease
-
van der Burg, J.M., Bacos, K., Wood, N.I., Lindqvist, A, Wierup, N., Woodman, B., Wamsteeker, J.I,, Smith, R., Deierborg, T., Kuhar, M.J. et al. (2008) Increased metabolism in the R6/2 mouse model of Huntington's disease. Neurobiol. Dis., 29, 41-51.
-
(2008)
Neurobiol. Dis
, vol.29
, pp. 41-51
-
-
van der Burg, J.M.1
Bacos, K.2
Wood, N.I.3
Lindqvist, A.4
Wierup, N.5
Woodman, B.6
Wamsteeker, J.I.7
Smith, R.8
Deierborg, T.9
Kuhar, M.J.10
-
22
-
-
40849120765
-
Obesity and lipodystrophy - where do the circles intersect?
-
Chehab, F.F. (2008) Obesity and lipodystrophy - where do the circles intersect? Endocrinol., 149, 925-934.
-
(2008)
Endocrinol
, vol.149
, pp. 925-934
-
-
Chehab, F.F.1
-
23
-
-
33746253894
-
Metabolic consequences of lipodystrophy in mouse models
-
Reue, K. and Phan, J. (2006) Metabolic consequences of lipodystrophy in mouse models. Curr. Opin. Clin. Nutr. Metabol. Care, 9, 436-441.
-
(2006)
Curr. Opin. Clin. Nutr. Metabol. Care
, vol.9
, pp. 436-441
-
-
Reue, K.1
Phan, J.2
-
24
-
-
38549111427
-
Impaired glucose tolerance in the R6/1 transgenic mouse model of Huntington's disease
-
Josefsen, K., Nielsen, M.D., Jorgensen, K.H., Bock, T., Norremolle, A., Sorensen, S.A., Naver, B. and Hasholt, L. (2008) Impaired glucose tolerance in the R6/1 transgenic mouse model of Huntington's disease. J. Neuroendocrinol., 20, 165-172.
-
(2008)
J. Neuroendocrinol
, vol.20
, pp. 165-172
-
-
Josefsen, K.1
Nielsen, M.D.2
Jorgensen, K.H.3
Bock, T.4
Norremolle, A.5
Sorensen, S.A.6
Naver, B.7
Hasholt, L.8
-
25
-
-
42249107018
-
Glucose homeostasis in Huntington disease: Abnormalities in insulin sensitivity and early-phase insulin secretion
-
Lalic, N.M., Marie, J., Svetel, M., Jotic, A., Stefanova, E., Lalic, K., Dragasevic, N., Milicic, T., Lukic, L. and Kostic, V.S. (2008) Glucose homeostasis in Huntington disease: Abnormalities in insulin sensitivity and early-phase insulin secretion. Arch. Neurol., 65, 476-480.
-
(2008)
Arch. Neurol
, vol.65
, pp. 476-480
-
-
Lalic, N.M.1
Marie, J.2
Svetel, M.3
Jotic, A.4
Stefanova, E.5
Lalic, K.6
Dragasevic, N.7
Milicic, T.8
Lukic, L.9
Kostic, V.S.10
-
26
-
-
43049096057
-
Adipokines and the peripheral and neural control of energy balance
-
Baltimore, Md
-
Ahinna, R.S. and Lazar, M.A. (2008) Adipokines and the peripheral and neural control of energy balance. Mol. Endocrinol. (Baltimore, Md. 22, 1023-1031.
-
(2008)
Mol. Endocrinol
, vol.22
, pp. 1023-1031
-
-
Ahinna, R.S.1
Lazar, M.A.2
-
27
-
-
45549086298
-
Adipose tissue hormones and the regulation of food intake
-
Henry, B.A. and Clarke, I.J. (2008) Adipose tissue hormones and the regulation of food intake. J. Neuroendocrinol., 20, 842-849.
-
(2008)
J. Neuroendocrinol
, vol.20
, pp. 842-849
-
-
Henry, B.A.1
Clarke, I.J.2
-
28
-
-
33747356154
-
Adipose tissue: From lipid storage compartment to endocrine organ
-
Scherer, P.E. (2006) Adipose tissue: From lipid storage compartment to endocrine organ. Diabetes, 55, 1537-1545.
-
(2006)
Diabetes
, vol.55
, pp. 1537-1545
-
-
Scherer, P.E.1
-
29
-
-
35348928193
-
Leptin-to-adiponectin ratio as independent predictor of insulin sensitivity during growth in overweight Hispanic youth
-
Koebnick, C., Shaibi, G.Q., Kelly, L.A., Roberts, C.K., Lane, C.J., Toledo-Corral, C., Davis, J.N., Byrd-Williams, C., Weigensberg, M.J. and Goran, M. I. (2007) Leptin-to-adiponectin ratio as independent predictor of insulin sensitivity during growth in overweight Hispanic youth. J. Endocrinol. Invest., 30, RC13-RC16.
-
(2007)
J. Endocrinol. Invest
, vol.30
-
-
Koebnick, C.1
Shaibi, G.Q.2
Kelly, L.A.3
Roberts, C.K.4
Lane, C.J.5
Toledo-Corral, C.6
Davis, J.N.7
Byrd-Williams, C.8
Weigensberg, M.J.9
Goran, M.I.10
-
30
-
-
34848832114
-
Leptin:aDiponectin ratio is an independent predictor of intima media thickness of the common carotid artery
-
Norata, G.D., Raselli, S., Grigore, L., Garlaschelli, K., Dozio, E., Magni, P. and Catapano, A.L. (2007) Leptin:aDiponectin ratio is an independent predictor of intima media thickness of the common carotid artery. Stroke, 38, 2844-2846.
-
(2007)
Stroke
, vol.38
, pp. 2844-2846
-
-
Norata, G.D.1
Raselli, S.2
Grigore, L.3
Garlaschelli, K.4
Dozio, E.5
Magni, P.6
Catapano, A.L.7
-
31
-
-
38049075329
-
The ratio of leptin to adiponectin can be used as an index of insulin resistance
-
Oda, N., Imamura, S., Fujita, T., Uchida, Y., Inagaki, K., Kakizawa, H., Hayakawa, N., Suzuki, A., Takeda, J., Horikawa, Y. et al. (2008) The ratio of leptin to adiponectin can be used as an index of insulin resistance. Metab. Clin. Exptl., 57, 268-273.
-
(2008)
Metab. Clin. Exptl
, vol.57
, pp. 268-273
-
-
Oda, N.1
Imamura, S.2
Fujita, T.3
Uchida, Y.4
Inagaki, K.5
Kakizawa, H.6
Hayakawa, N.7
Suzuki, A.8
Takeda, J.9
Horikawa, Y.10
-
32
-
-
26844498655
-
The use of the R6 transgenic mouse models of Huntington's disease in attempts to develop novel therapeutic strategies
-
Li, J.Y., Popovic, N. and Brundin, P. (2005) The use of the R6 transgenic mouse models of Huntington's disease in attempts to develop novel therapeutic strategies. NeuroRx, 2, 447-464.
-
(2005)
NeuroRx
, vol.2
, pp. 447-464
-
-
Li, J.Y.1
Popovic, N.2
Brundin, P.3
-
33
-
-
0041691176
-
Time course of varly motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats
-
Menalled, L.B., Sison, J.D., Dragatsis, L, Zeitlin, S. and Chesselet, M.F. (2003) Time course of varly motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats. J. Comp. Neurol., 465, 11-26.
-
(2003)
J. Comp. Neurol
, vol.465
, pp. 11-26
-
-
Menalled, L.B.1
Sison, J.D.2
Dragatsis, L.3
Zeitlin, S.4
Chesselet, M.F.5
-
34
-
-
54549087605
-
Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice
-
Hickey, M.A., Kosmalska, A., Enayati, J., Cohen, R., Zeitlin, S., Levine, M. and Chesselet, M.F. (2008) Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice. Neuroscience, 157, 280-295.
-
(2008)
Neuroscience
, vol.157
, pp. 280-295
-
-
Hickey, M.A.1
Kosmalska, A.2
Enayati, J.3
Cohen, R.4
Zeitlin, S.5
Levine, M.6
Chesselet, M.F.7
-
35
-
-
34247556686
-
Adipose tissue as an endocrine organ
-
Ahima, R.S. (2006) Adipose tissue as an endocrine organ. Obesity, 14 (Suppl. 5), 242S-249S.
-
(2006)
Obesity
, vol.14
, Issue.SUPPL. 5
-
-
Ahima, R.S.1
-
36
-
-
33845592201
-
Adipose tissue-derived factors: Impact on health and disease
-
Trujillo, M.E. and Scherer, P.E. (2006) Adipose tissue-derived factors: impact on health and disease. Endocrinol. Rev., 27, 762-778.
-
(2006)
Endocrinol. Rev
, vol.27
, pp. 762-778
-
-
Trujillo, M.E.1
Scherer, P.E.2
-
37
-
-
19044393872
-
Adipose tissue, inflammation, and cardiovascular disease
-
Berg, A.H. and Scherer, P.E. (2004) Adipose tissue, inflammation, and cardiovascular disease. Circ. Res., 96, 939-949.
-
(2004)
Circ. Res
, vol.96
, pp. 939-949
-
-
Berg, A.H.1
Scherer, P.E.2
-
38
-
-
33748942837
-
Transcriptional control of adipocyte formation
-
Farmer, S.R. (2006) Transcriptional control of adipocyte formation. Cell Metab., 4, 263-273.
-
(2006)
Cell Metab
, vol.4
, pp. 263-273
-
-
Farmer, S.R.1
-
39
-
-
33845325476
-
Adipocyte differentiation from the inside out
-
Rosen, E.D. and MacDougald, O.A. (2006) Adipocyte differentiation from the inside out. Nat. Rev. Mol. Cell Biol., 7, 885-896.
-
(2006)
Nat. Rev. Mol. Cell Biol
, vol.7
, pp. 885-896
-
-
Rosen, E.D.1
MacDougald, O.A.2
-
40
-
-
0033571743
-
Enhanced sensitivity to N-methyl-D-aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease
-
Levine, M.S., Klapstein, G.J., Koppel, A., Gruen, E., Cepeda, C., Vargas, M.E., Jokel, E.S., Carpenter, E.M., Zanjani, H., Hurst, R.S. et al. (1999) Enhanced sensitivity to N-methyl-D-aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease. J. Neurosci. Res., 58, 515-532.
-
(1999)
J. Neurosci. Res
, vol.58
, pp. 515-532
-
-
Levine, M.S.1
Klapstein, G.J.2
Koppel, A.3
Gruen, E.4
Cepeda, C.5
Vargas, M.E.6
Jokel, E.S.7
Carpenter, E.M.8
Zanjani, H.9
Hurst, R.S.10
-
41
-
-
33749042331
-
Transcriptional repression of PGC-1 alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration
-
Cui, L., Jeong, H., Borovecki, F., Parkhurst, C.N., Tanese, N. and Krainc, D. (2006) Transcriptional repression of PGC-1 alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration. Cell, 127, 59-69.
-
(2006)
Cell
, vol.127
, pp. 59-69
-
-
Cui, L.1
Jeong, H.2
Borovecki, F.3
Parkhurst, C.N.4
Tanese, N.5
Krainc, D.6
-
42
-
-
33749999530
-
Suppression of reactive oxygen species and nearodegeneration by the PGC-1 transcriptional coactivators
-
St-Pierre, J., Drori, S., Uldry, M., Silvaggi, J.M., Rhee, J., Jager, S., Handschin, C., Zheng, K., Lin, J., Yang, W. et al. (2006) Suppression of reactive oxygen species and nearodegeneration by the PGC-1 transcriptional coactivators. Cell, 127, 397-408.
-
(2006)
Cell
, vol.127
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
Silvaggi, J.M.4
Rhee, J.5
Jager, S.6
Handschin, C.7
Zheng, K.8
Lin, J.9
Yang, W.10
-
43
-
-
33747853190
-
Lipin I is an inducible amplifier of the hepatic PGCT-1alpha/PPARalpha regulatory pathway
-
Finck, B.N., Gropler, M.C., Chen, Z., Leone, T.C., Croce, M.A., Harris, T.E., Lawrence, J.C. Jr and Kelly, D.P. (2006) Lipin I is an inducible amplifier of the hepatic PGCT-1alpha/PPARalpha regulatory pathway. Cell Metab., 4, 199-210.
-
(2006)
Cell Metab
, vol.4
, pp. 199-210
-
-
Finck, B.N.1
Gropler, M.C.2
Chen, Z.3
Leone, T.C.4
Croce, M.A.5
Harris, T.E.6
Lawrence Jr, J.C.7
Kelly, D.P.8
-
44
-
-
24144463983
-
Metabolic control through the PGC-1 family of transcription coactivators
-
Lin, J., Handsehin, C. and Spiegelman, B.M. (2005) Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab. 11, 361-370.
-
(2005)
Cell Metab
, vol.11
, pp. 361-370
-
-
Lin, J.1
Handsehin, C.2
Spiegelman, B.M.3
-
45
-
-
1542510700
-
Acquired and inherited lipodystrophies
-
Garg, A. (2004) Acquired and inherited lipodystrophies. N. Engl. J. Med., 350, 1220-1234.
-
(2004)
N. Engl. J. Med
, vol.350
, pp. 1220-1234
-
-
Garg, A.1
-
46
-
-
7244258816
-
Circulating and cerebrospinal fluid ghrelin and leptin: Potential role in altered body weight in Huntington's disease
-
Popovic, V., Svetel, M., Djurovic, M., Petrovic, S., Doknic, M., Pekic, S., Mitjic, D., Milic, N., Glodic, J., Dieguez, C. et al. (2004) Circulating and cerebrospinal fluid ghrelin and leptin: Potential role in altered body weight in Huntington's disease. Eur. J Endocrinol. 151, 451-455.
-
(2004)
Eur. J Endocrinol
, vol.151
, pp. 451-455
-
-
Popovic, V.1
Svetel, M.2
Djurovic, M.3
Petrovic, S.4
Doknic, M.5
Pekic, S.6
Mitjic, D.7
Milic, N.8
Glodic, J.9
Dieguez, C.10
-
47
-
-
33744504676
-
Mechanisms of disease: Histone modifications in Huntington's disease
-
Sadri-Vakili, G. and Cha, J.H. (2006) Mechanisms of disease: Histone modifications in Huntington's disease. Nat. Clin. Pract. Neurol., 2, 330-338.
-
(2006)
Nat. Clin. Pract. Neurol
, vol.2
, pp. 330-338
-
-
Sadri-Vakili, G.1
Cha, J.H.2
-
48
-
-
35348877164
-
Transcriptional signatures in Huntington's disease
-
Cha, J.H. (2007) Transcriptional signatures in Huntington's disease. Prog. Neurobiol., 83, 228-248.
-
(2007)
Prog. Neurobiol
, vol.83
, pp. 228-248
-
-
Cha, J.H.1
-
49
-
-
10944265363
-
Mutant huntingtin affects the rate of transcription of striatum-specific isoforms of phosphodiesterase 10A
-
Hu, H., McCaw, E.A., Hebb, A.L., Gomez, G.T. and Denovan-Wright, E.M. (2004)Mutant huntingtin affects the rate of transcription of striatum-specific isoforms of phosphodiesterase 10A. Eur. J. Neurosci., 20, 3351-3363.
-
(2004)
Eur. J. Neurosci
, vol.20
, pp. 3351-3363
-
-
Hu, H.1
McCaw, E.A.2
Hebb, A.L.3
Gomez, G.T.4
Denovan-Wright, E.M.5
-
50
-
-
0034702030
-
Dqcreased expression of striatal signaling genes in a mouse model of Huntington's disease
-
Luthi-Carter, R., Strand, A., Peters, N.L., Solano, S.M., Hollingsworth, Z.R., Menon, A.S., Frey, A.S,., Spektor, B.S., Penney, E.B., Schilling, G. et al. (2000) Dqcreased expression of striatal signaling genes in a mouse model of Huntington's disease. Hum. Mol. Genet., 9 1259-1271.
-
(2000)
Hum. Mol. Genet
, vol.9
, pp. 1259-1271
-
-
Luthi-Carter, R.1
Strand, A.2
Peters, N.L.3
Solano, S.M.4
Hollingsworth, Z.R.5
Menon, A.S.6
Frey, A.S.7
Spektor, B.S.8
Penney, E.B.9
Schilling, G.10
-
51
-
-
11244306357
-
Structure, expression and regulation of the cannabinoid receptor gene (CB1) in Huntington's disease transgenic mice
-
McCaw, E.A., Hu, H., Gomez, G.T., Hebb, A.L., Kelly, M.E. and Denovan-Wright, E.M. (2004) Structure, expression and regulation of the cannabinoid receptor gene (CB1) in Huntington's disease transgenic mice Eur. J. Biochem., 271; 4909-4920.
-
(2004)
Eur. J. Biochem
, vol.271
, pp. 4909-4920
-
-
McCaw, E.A.1
Hu, H.2
Gomez, G.T.3
Hebb, A.L.4
Kelly, M.E.5
Denovan-Wright, E.M.6
-
52
-
-
23344448837
-
Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease
-
Borovecki, F., Lovrecic, L., Zhou, J., Jeong, H., Then, F., Rosas, H.D., Hersch, S.M., Hogarth, P., Bouzou, B., Jensen, R.V. et al. (2005) Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease. Proc. Natl Acad. Sci., 102, 11023-11028.
-
(2005)
Proc. Natl Acad. Sci
, vol.102
, pp. 11023-11028
-
-
Borovecki, F.1
Lovrecic, L.2
Zhou, J.3
Jeong, H.4
Then, F.5
Rosas, H.D.6
Hersch, S.M.7
Hogarth, P.8
Bouzou, B.9
Jensen, R.V.10
-
53
-
-
29244462838
-
In vitro analysis of huntingtin-mediated transcriptional repression reveals multiple transcription factor targets
-
Zhai, W., Jeong, H, Cui, L., Krainc, D. Ad Tjian, R. (2005) In vitro analysis of huntingtin-mediated transcriptional repression reveals multiple transcription factor targets. Cell, 123, 1241-1253.
-
(2005)
Cell
, vol.123
, pp. 1241-1253
-
-
Zhai, W.1
Jeong, H.2
Cui, L.3
Krainc, D.A.4
Tjian, R.5
-
54
-
-
49449091708
-
Huntington's disease protein contributes to RNA-mediated gene silencing through association with Argonaute and P bodies
-
Savas, J.N., Makusky, A., Ottosen, S., Baillat, D., Then, F., Krainc, D., Shiekhattar, R., Markey, S.P. and Tanese, N. (2008) Huntington's disease protein contributes to RNA-mediated gene silencing through association with Argonaute and P bodies. PNAS, 105, 10820-10825.
-
(2008)
PNAS
, vol.105
, pp. 10820-10825
-
-
Savas, J.N.1
Makusky, A.2
Ottosen, S.3
Baillat, D.4
Then, F.5
Krainc, D.6
Shiekhattar, R.7
Markey, S.P.8
Tanese, N.9
-
55
-
-
21144446106
-
-
Leone, T.C., Lehman, J.J., Finck, B.N.,-Schaeffer, P.J., Wende, A.R., Boudina, S., Courtois, M., Wozniak, D.P., Sambandam, N., Bernal-Mizrachi, C. et al. (2005) PGC-1alpha deficiency causes multi-system energy metabolic derangements: Muscle dysfunction, abnormal weight control and hepatic steatosis. PLoS Biol., 3, e101.
-
Leone, T.C., Lehman, J.J., Finck, B.N.,-Schaeffer, P.J., Wende, A.R., Boudina, S., Courtois, M., Wozniak, D.P., Sambandam, N., Bernal-Mizrachi, C. et al. (2005) PGC-1alpha deficiency causes multi-system energy metabolic derangements: Muscle dysfunction, abnormal weight control and hepatic steatosis. PLoS Biol., 3, e101.
-
-
-
-
56
-
-
5344252327
-
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice
-
Lin, J., Wu, P.H., Tarr, P.T., Lindenberg, K.S., St-Pierre, J., Zhang, C.Y., Mootha, V.K., Jager, S., Vianna, C.R., Reznick, R.M. et al. (2004) Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice. Cell, 119, 121-135.
-
(2004)
Cell
, vol.119
, pp. 121-135
-
-
Lin, J.1
Wu, P.H.2
Tarr, P.T.3
Lindenberg, K.S.4
St-Pierre, J.5
Zhang, C.Y.6
Mootha, V.K.7
Jager, S.8
Vianna, C.R.9
Reznick, R.M.10
-
57
-
-
24044442568
-
Early behavioral deficits in R6/2 mice suitable for use in preclinical drug testing
-
Hickey, M.A., Gallant, K., Gross, G.G., Levine, M.S. and Chesselet, M.F. (2005) Early behavioral deficits in R6/2 mice suitable for use in preclinical drug testing. Neurobiol. Dis., 20, 1-11.
-
(2005)
Neurobiol. Dis
, vol.20
, pp. 1-11
-
-
Hickey, M.A.1
Gallant, K.2
Gross, G.G.3
Levine, M.S.4
Chesselet, M.F.5
-
58
-
-
54449092109
-
Rosiglitazone treatment prevents mitochondrial dysfunction in mutant huntingtin expressing cells: Possible role of PPARgamma in the pathogenesis of huntington disease
-
Quintanilla, R.A., Jin, Y.N., Fuenzalida, K., Bronfman. M. and Johnson, G.V. (2008) Rosiglitazone treatment prevents mitochondrial dysfunction in mutant huntingtin expressing cells: Possible role of PPARgamma in the pathogenesis of huntington disease. J. Biol. Chem., 283, 25628-25637.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 25628-25637
-
-
Quintanilla, R.A.1
Jin, Y.N.2
Fuenzalida, K.3
Bronfman, M.4
Johnson, G.V.5
-
59
-
-
44049091481
-
Peroxisome proliferator-activated receptor-gamma in amyotrophic lateral sclerosis and Huntington's disease
-
Kjaci, M. (2008) Peroxisome proliferator-activated receptor-gamma in amyotrophic lateral sclerosis and Huntington's disease. PPAR Res., 2008, 418765.
-
(2008)
PPAR Res
, vol.2008
, pp. 418765
-
-
Kjaci, M.1
-
60
-
-
3142685480
-
Lipin expression preceding peroxisome proliferator-activated receptor-gamma is critical for adipogenesis in vivo and in vitro
-
Phan, J., Peterly, M. and Reue, K. (2004) Lipin expression preceding peroxisome proliferator-activated receptor-gamma is critical for adipogenesis in vivo and in vitro. J. Bio. Chem., 279, 29558-29564.
-
(2004)
J. Bio. Chem
, vol.279
, pp. 29558-29564
-
-
Phan, J.1
Peterly, M.2
Reue, K.3
-
61
-
-
3242723420
-
A cell-based screen for drugs to treat Huntington's disease
-
Aiken, C.T., Tobin, A.J. and Schweitzer, E.S. (2004) A cell-based screen for drugs to treat Huntington's disease. Neurobiol. Dis., 16 546-555.
-
(2004)
Neurobiol. Dis
, vol.16
, pp. 546-555
-
-
Aiken, C.T.1
Tobin, A.J.2
Schweitzer, E.S.3
-
62
-
-
0029662678
-
Safety testing of tebufenozide, a new molt-inducing insecticide, for effects on nontarget forest soil invertebrates
-
Addison, J.A. (1996) Safety testing of tebufenozide, a new molt-inducing insecticide, for effects on nontarget forest soil invertebrates. Ecotoxicol. Environ. Saf., 33, 55-61.
-
(1996)
Ecotoxicol. Environ. Saf
, vol.33
, pp. 55-61
-
-
Addison, J.A.1
-
63
-
-
0026705751
-
Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
-
Kliewer, S.A., Umesono, K., Noonan, D.J., Heyman, R.A. and Evans, R.M. (1992) Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature, 358, 771-774.
-
(1992)
Nature
, vol.358
, pp. 771-774
-
-
Kliewer, S.A.1
Umesono, K.2
Noonan, D.J.3
Heyman, R.A.4
Evans, R.M.5
|