-
1
-
-
0033969766
-
TAFs revisited: More data reveal new twists and confirm old ideas
-
S.R. Albright, and R. Tjian TAFs revisited: more data reveal new twists and confirm old ideas Gene 242 2000 1 13
-
(2000)
Gene
, vol.242
, pp. 1-13
-
-
Albright, S.R.1
Tjian, R.2
-
2
-
-
0034283877
-
Transcriptional dysregulation in Huntington's disease
-
J.H. Cha Transcriptional dysregulation in Huntington's disease Trends Neurosci. 23 2000 387 392
-
(2000)
Trends Neurosci.
, vol.23
, pp. 387-392
-
-
Cha, J.H.1
-
3
-
-
0028108925
-
Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators
-
J.L. Chen, L.D. Attardi, C.P. Verrijzer, K. Yokomori, and R. Tjian Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators Cell 79 1994 93 105
-
(1994)
Cell
, vol.79
, pp. 93-105
-
-
Chen, J.L.1
Attardi, L.D.2
Verrijzer, C.P.3
Yokomori, K.4
Tjian, R.5
-
5
-
-
0024276524
-
Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif
-
A.J. Courey, and R. Tjian Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif Cell 55 1988 887 898
-
(1988)
Cell
, vol.55
, pp. 887-898
-
-
Courey, A.J.1
Tjian, R.2
-
6
-
-
0028989602
-
Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons
-
M. DiFiglia, E. Sapp, K. Chase, C. Schwarz, A. Meloni, C. Young, E. Martin, J.P. Vonsattel, R. Carraway, and S.A. Reeves Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons Neuron 14 1995 1075 1081
-
(1995)
Neuron
, vol.14
, pp. 1075-1081
-
-
Difiglia, M.1
Sapp, E.2
Chase, K.3
Schwarz, C.4
Meloni, A.5
Young, C.6
Martin, E.7
Vonsattel, J.P.8
Carraway, R.9
Reeves, S.A.10
-
7
-
-
0030752709
-
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
-
M. DiFiglia, E. Sapp, K.O. Chase, S.W. Davies, G.P. Bates, J.P. Vonsattel, and N. Aronin Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain Science 277 1997 1990 1993
-
(1997)
Science
, vol.277
, pp. 1990-1993
-
-
Difiglia, M.1
Sapp, E.2
Chase, K.O.3
Davies, S.W.4
Bates, G.P.5
Vonsattel, J.P.6
Aronin, N.7
-
8
-
-
0037150687
-
Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease
-
A.W. Dunah, H. Jeong, A. Griffin, Y.M. Kim, D.G. Standaert, S.M. Hersch, M.M. Mouradian, A.B. Young, N. Tanese, and D. Krainc Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease Science 296 2002 2238 2243
-
(2002)
Science
, vol.296
, pp. 2238-2243
-
-
Dunah, A.W.1
Jeong, H.2
Griffin, A.3
Kim, Y.M.4
Standaert, D.G.5
Hersch, S.M.6
Mouradian, M.M.7
Young, A.B.8
Tanese, N.9
Krainc, D.10
-
9
-
-
0035805497
-
Heat shock factor-4 (HSF-4a) represses basal transcription through interaction with TFIIF
-
W. Frejtag, Y. Zhang, R. Dai, M.G. Anderson, and N.F. Mivechi Heat shock factor-4 (HSF-4a) represses basal transcription through interaction with TFIIF J. Biol. Chem. 276 2001 14685 14694
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 14685-14694
-
-
Frejtag, W.1
Zhang, Y.2
Dai, R.3
Anderson, M.G.4
Mivechi, N.F.5
-
10
-
-
0034613012
-
Novel dimerization fold of RAP30/RAP74 in human TFIIF at 1.7 Å resolution
-
F. Gaiser, S. Tan, and T.J. Richmond Novel dimerization fold of RAP30/RAP74 in human TFIIF at 1.7 Å resolution J. Mol. Biol. 302 2000 1119 1127
-
(2000)
J. Mol. Biol.
, vol.302
, pp. 1119-1127
-
-
Gaiser, F.1
Tan, S.2
Richmond, T.J.3
-
11
-
-
0027103173
-
The carboxyl terminus of RAP30 is similar in sequence to region 4 of bacterial sigma factors and is required for function
-
K.P. Garrett, H. Serizawa, J.P. Hanley, J.N. Bradsher, A. Tsuboi, N. Arai, T. Yokota, K. Arai, R.C. Conaway, and J.W. Conaway The carboxyl terminus of RAP30 is similar in sequence to region 4 of bacterial sigma factors and is required for function J. Biol. Chem. 267 1992 23942 23949
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 23942-23949
-
-
Garrett, K.P.1
Serizawa, H.2
Hanley, J.P.3
Bradsher, J.N.4
Tsuboi, A.5
Arai, N.6
Yokota, T.7
Arai, K.8
Conaway, R.C.9
Conaway, J.W.10
-
12
-
-
23444458415
-
Transcriptional activation modulated by homopolymeric glutamine and proline stretches
-
H.P. Gerber, K. Seipel, O. Georgiev, M. Hofferer, M. Hug, S. Rusconi, and W. Schaffner Transcriptional activation modulated by homopolymeric glutamine and proline stretches Science 263 1994 808 811
-
(1994)
Science
, vol.263
, pp. 808-811
-
-
Gerber, H.P.1
Seipel, K.2
Georgiev, O.3
Hofferer, M.4
Hug, M.5
Rusconi, S.6
Schaffner, W.7
-
13
-
-
0346220220
-
General transcriptional repression by polyglutamine disease proteins is not directly linked to the presence of inclusion bodies
-
M. Hoshino, K. Tagawa, T. Okuda, and H. Okazawa General transcriptional repression by polyglutamine disease proteins is not directly linked to the presence of inclusion bodies Biochem. Biophys. Res. Commun. 313 2004 110 116
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.313
, pp. 110-116
-
-
Hoshino, M.1
Tagawa, K.2
Okuda, T.3
Okazawa, H.4
-
14
-
-
0035924326
-
Selectivity of chromatin-remodelling cofactors for ligand-activated transcription
-
B. Lemon, C. Inouye, D.S. King, and R. Tjian Selectivity of chromatin-remodelling cofactors for ligand-activated transcription Nature 414 2001 924 928
-
(2001)
Nature
, vol.414
, pp. 924-928
-
-
Lemon, B.1
Inouye, C.2
King, D.S.3
Tjian, R.4
-
15
-
-
0036173896
-
Interaction of Huntington disease protein with transcriptional activator Sp1
-
S.H. Li, A.L. Cheng, H. Zhou, S. Lam, M. Rao, H. Li, and X.J. Li Interaction of Huntington disease protein with transcriptional activator Sp1 Mol. Cell. Biol. 22 2002 1277 1287
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 1277-1287
-
-
Li, S.H.1
Cheng, A.L.2
Zhou, H.3
Lam, S.4
Rao, M.5
Li, H.6
Li, X.J.7
-
16
-
-
0037101835
-
Dysregulation of gene expression in the R6/2 model of polyglutamine disease: Parallel changes in muscle and brain
-
R. Luthi-Carter, S.A. Hanson, A.D. Strand, D.A. Bergstrom, W. Chun, N.L. Peters, A.M. Woods, E.Y. Chan, C. Kooperberg, and D. Krainc Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain Hum. Mol. Genet. 11 2002 1911 1926
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1911-1926
-
-
Luthi-Carter, R.1
Hanson, S.A.2
Strand, A.D.3
Bergstrom, D.A.4
Chun, W.5
Peters, N.L.6
Woods, A.M.7
Chan, E.Y.8
Kooperberg, C.9
Krainc, D.10
-
17
-
-
0037101837
-
Polyglutamine and transcription: Gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects
-
R. Luthi-Carter, A.D. Strand, S.A. Hanson, C. Kooperberg, G. Schilling, A.R. La Spada, D.E. Merry, A.B. Young, C.A. Ross, D.R. Borchelt, and J.M. Olson Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects Hum. Mol. Genet. 11 2002 1927 1937
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1927-1937
-
-
Luthi-Carter, R.1
Strand, A.D.2
Hanson, S.A.3
Kooperberg, C.4
Schilling, G.5
La Spada, A.R.6
Merry, D.E.7
Young, A.B.8
Ross, C.A.9
Borchelt, D.R.10
Olson, J.M.11
-
18
-
-
16044373842
-
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
L. Mangiarini, K. Sathasivam, M. Seller, B. Cozens, A. Harper, C. Hetherington, M. Lawton, Y. Trottier, H. Lehrach, S.W. Davies, and G.P. Bates Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice Cell 87 1996 493 506
-
(1996)
Cell
, vol.87
, pp. 493-506
-
-
Mangiarini, L.1
Sathasivam, K.2
Seller, M.3
Cozens, B.4
Harper, A.5
Hetherington, C.6
Lawton, M.7
Trottier, Y.8
Lehrach, H.9
Davies, S.W.10
Bates, G.P.11
-
19
-
-
0025834732
-
Related RNA polymerase-binding regions in human RAP30/74 and Escherichia coli sigma 70
-
S. McCracken, and J. Greenblatt Related RNA polymerase-binding regions in human RAP30/74 and Escherichia coli sigma 70 Science 253 1991 900 902
-
(1991)
Science
, vol.253
, pp. 900-902
-
-
McCracken, S.1
Greenblatt, J.2
-
20
-
-
0041691176
-
Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats
-
L.B. Menalled, J.D. Sison, I. Dragatsis, S. Zeitlin, and M.F. Chesselet Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats J. Comp. Neurol. 465 2003 11 26
-
(2003)
J. Comp. Neurol.
, vol.465
, pp. 11-26
-
-
Menalled, L.B.1
Sison, J.D.2
Dragatsis, I.3
Zeitlin, S.4
Chesselet, M.F.5
-
21
-
-
0040368298
-
Composite co-activator ARC mediates chromatin-directed transcriptional activation
-
A.M. Naar, P.A. Beaurang, S. Zhou, S. Abraham, W. Solomon, and R. Tjian Composite co-activator ARC mediates chromatin-directed transcriptional activation Nature 398 1999 828 832
-
(1999)
Nature
, vol.398
, pp. 828-832
-
-
Naar, A.M.1
Beaurang, P.A.2
Zhou, S.3
Abraham, S.4
Solomon, W.5
Tjian, R.6
-
22
-
-
0042869974
-
Polyglutamine diseases: A transcription disorder?
-
H. Okazawa Polyglutamine diseases: a transcription disorder? Cell. Mol. Life Sci. 60 2003 1427 1439
-
(2003)
Cell. Mol. Life Sci.
, vol.60
, pp. 1427-1439
-
-
Okazawa, H.1
-
24
-
-
0037174879
-
Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization
-
M.A. Poirer, H. Li, J. Macosko, S. Cai, M. Amzel, and C.A. Ross Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization J. Biol. Chem. 277 2002 41032 41037
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 41032-41037
-
-
Poirer, M.A.1
Li, H.2
MacOsko, J.3
Cai, S.4
Amzel, M.5
Ross, C.A.6
-
25
-
-
0027519511
-
Analysis of the huntingtin gene reveals a trinucleotide-length polymorphism in the region of the gene that contains two CCG-rich stretches and a correlation between decreased age of onset of Huntington's disease and CAG repeat number
-
D.C. Rubinsztein, D.E. Barton, B.C. Davison, and M.A. Ferguson-Smith Analysis of the huntingtin gene reveals a trinucleotide-length polymorphism in the region of the gene that contains two CCG-rich stretches and a correlation between decreased age of onset of Huntington's disease and CAG repeat number Hum. Mol. Genet. 2 1993 1713 1715
-
(1993)
Hum. Mol. Genet.
, vol.2
, pp. 1713-1715
-
-
Rubinsztein, D.C.1
Barton, D.E.2
Davison, B.C.3
Ferguson-Smith, M.A.4
-
26
-
-
0033521956
-
The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1
-
S. Ryu, S. Zhou, A.G. Ladurner, and R. Tjian The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1 Nature 397 1999 446 450
-
(1999)
Nature
, vol.397
, pp. 446-450
-
-
Ryu, S.1
Zhou, S.2
Ladurner, A.G.3
Tjian, R.4
-
27
-
-
0032475931
-
Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions
-
F. Saudou, S. Finkbeiner, D. Devys, and M.E. Greenberg Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions Cell 95 1998 55 66
-
(1998)
Cell
, vol.95
, pp. 55-66
-
-
Saudou, F.1
Finkbeiner, S.2
Devys, D.3
Greenberg, M.E.4
-
28
-
-
18544400323
-
Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo
-
E. Scherzinger, R. Lurz, M. Turmaine, L. Mangiarini, B. Hollenback, R. Hasenbank, G.P. Bates, S.W. Davies, H. Lehrach, and E.E. Wanker Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo Cell 90 1997 549 558
-
(1997)
Cell
, vol.90
, pp. 549-558
-
-
Scherzinger, E.1
Lurz, R.2
Turmaine, M.3
Mangiarini, L.4
Hollenback, B.5
Hasenbank, R.6
Bates, G.P.7
Davies, S.W.8
Lehrach, H.9
Wanker, E.E.10
-
29
-
-
0034791680
-
Modeling Huntington's disease in cells, flies, and mice
-
S. Sipione, and E. Cattaneo Modeling Huntington's disease in cells, flies, and mice Mol. Neurobiol. 23 2001 21 51
-
(2001)
Mol. Neurobiol.
, vol.23
, pp. 21-51
-
-
Sipione, S.1
Cattaneo, E.2
-
30
-
-
0035909330
-
Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila
-
J.S. Steffan, L. Bodai, J. Pallos, M. Poelman, A. McCampbell, B.L. Apostol, A. Kazantsev, E. Schmidt, Y.Z. Zhu, and M. Greenwald Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila Nature 413 2001 739 743
-
(2001)
Nature
, vol.413
, pp. 739-743
-
-
Steffan, J.S.1
Bodai, L.2
Pallos, J.3
Poelman, M.4
McCampbell, A.5
Apostol, B.L.6
Kazantsev, A.7
Schmidt, E.8
Zhu, Y.Z.9
Greenwald, M.10
-
31
-
-
0037408279
-
Transcriptional abnormalities in Huntington disease
-
K.L. Sugars, and D.C. Rubinsztein Transcriptional abnormalities in Huntington disease Trends Genet. 19 2003 233 238
-
(2003)
Trends Genet.
, vol.19
, pp. 233-238
-
-
Sugars, K.L.1
Rubinsztein, D.C.2
-
32
-
-
0029034913
-
Dissection of transcription factor TFIIF functional domains required for initiation and elongation
-
S. Tan, R.C. Conaway, and J.W. Conaway Dissection of transcription factor TFIIF functional domains required for initiation and elongation Proc. Natl. Acad. Sci. USA 92 1995 6042 6046
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 6042-6046
-
-
Tan, S.1
Conaway, R.C.2
Conaway, J.W.3
-
33
-
-
0025786590
-
Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex
-
N. Tanese, B.F. Pugh, and R. Tjian Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex Genes Dev. 5 1991 2212 2224
-
(1991)
Genes Dev.
, vol.5
, pp. 2212-2224
-
-
Tanese, N.1
Pugh, B.F.2
Tjian, R.3
-
34
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
The Huntington's Disease Collaborative Research Group
-
The Huntington's Disease Collaborative Research Group A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes Cell 72 1993 971 983
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
|